Name of Product Lepinox Plus Registration Number 2018-03-15 P01 Bacillus thuringensis subspecies kurstaki strain EG 2348 Active Substance 37.5% w/w Authorisation Holder CBC (Europe) S.r.l Expiry Date of Authorisation 15/03/2022 Type of Authorisation Mutual Recognition (Italy) Type of Plant Protection Product Insecticide Administrative Status Authorised FRUIT CROPS - Pome fruits (apple, pear, quince): Tortricid Crop – Relevant Pest – Relevant moths (Argyrotaenia spp., Pandemis spp., Archips podana, Dose – Preharvest Interval (PHI) Adoxophyes orana), Rusty tussock moth (Orgyia antiqua), Quince moth (Euzophera bigella) 0.75 - 1.5 Kg/ha, with water volume of 600-1500 L/ha. - Stone fruits (peach, nectarine, processing peach, apricot, plum, cherry): Oriental fruit moth (Cydia molesta), Peach twig borer (Anarsia lineatella) 0.75 - 1.5 Kg/ha, with water volume of 600-1500 L/ha. - Kiwifruit: Grape tortrix moth (Argyrotaenia pulchellana), Copper underwing moth (Amphipyra pyramidea) 0.75 - 1.5 Kg/ha, with water volume of 600-1500 L/ha. GRAPE VINE AND TABLE GRAPE: Grape berry moths (Eupoecilia ambiguella, Lobesia botrana) 0.75 - 1.5 Kg/ha, with water volume of 100-1500 L/ha. VEGETABLES - Cabbages (cauliflower, broccoli, savoy cabbage, head cabbage, Chinese cabbage, Brussels sprouts, turnip cabbage): Large (cabbage) white (Pieris brassicae), Noctuid moths (Spodoptera littoralis), Diamond back moth (Plutella xylostella) 0.75 - 1.5 Kg/ha, with water volume of 500-1500 L/ha; Cabbage moth (Mamestra brassicae) 1 - 1.5 Kg/ha, with water volume of 500-1500 L/ha. Open field and protected use. - Artichoke: Artichoke moth (Gortyna xanthenes) 0.75 - 1.5 Kg/ha, with water volume of 500-1500 L/ha. - Leaf vegetables (lettuce, chicory, endive, radicchio, escarole, garden rocket, corn salad, spinach, leaf beet and chard, cardoon, celery, fennel, parsley, chive, basil): Noctuid moths (Spodoptera littoralis, Helicoverpa armigera, Chrysodeixis chalcites) 0.75 - 1.5 Kg/ha, with water volume of 500-1000 L/ha. Open field and protected use. - Bean and French bean: Noctuid moth (Helicoverpa armigera) 0.75 - 1.5 Kg/ha, with water volume of 500-1000 L/ha. Open field and protected use. - Cucurbits (water melon, melon, pumpkin, courgette, cucumber): Noctuid moths (Spodoptera littoralis, Helicoverpa armigera) 0.75 - 1.5 Kg/ha, with water volume 600-1500 L/ha. Open field and protected use.- Solanaceous fruits (tomato, aubergine, sweet pepper): Noctuid moths (Spodoptera littoralis, Spodoptera exigua), Tomato leafminer (Tuta absoluta) 0.75 - 1.5 Kg/ha, with water volume of 500-1500 L/ha; Cotton bollworm (Helicoverpa armigera), Cabbage moth (Mamestra brassicae, Mamestra olearacea) 1 - 1.5 Kg/ha, with water volume of 500-1500 L/ha. Open field and protected use. STRAWBERRY: Noctuid moths (Spodoptera littoralis) 0.75 - 1.5 Kg/ha, with water volume of 500-1500 L/ha. Open field and protected use. FLOWERS AND ORNAMENTALS: Noctuid moths 0.75 - 1.5 Kg/ha, with water volume of 600- 1500 L/ha. Open field and protected use. HOP: European corn borer (Ostrinia nubilalis) 0.75 - 1.5 Kg/ha, with water volume of 600-1500 L/ha. COTTON, TOBACCO: Cotton bollworm (Helicoverpa armigera) 1 - 1.5 Kg/ha, with water volume of 500-1500 L/ha. Apply at hatched eggs and young larvae stages (1st stage). Repeat treatments after 7 - 10 days if the critical period (i.e. Hatching and presence of early larval stages) exceeds this duration. Local conditions may suggest the use of LEPINOX® PLUS at specific times, in this case follow local technical instructions. Maximum number of treatments: 3. PRECAUTIONARY STATEMENTS LEPINOX PLUS In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible). In case of poisoning call a doctor for first aid treatments. Wear suitable BIOLOGICAL INSECTICIDE FOR THE CONTROL OF LEPIDOPTERAN respiratory protective equipment during treatments. PESTS - WETTABLE POWDER (WP) FORMULATION CHARACTERISTICS LEPINOX® PLUS is a highly selective biological insecticide for use against the lepidopteran COMPOSITION 100 grams of product contain: larvae. Larvae need ingest the product to become infected: treat young larvae that feed voraciously before there has been an excessive foliar injury. Make target treatments against early larval stages just after hatching (stages I and II) and, in particular, while the larvae are outside the plant.After Bacillus thuringiensis subspecies kurstaki strain EG 2348 g 37,50 ® Coformulants up to g 100 consuming a lethal dose of LEPINOX PLUS, larvae will cease to feed, but may remain alive on ® foliage for several days before dying. Immediately after ingestion of a lethal dose of LEPINOX Potency: 32.000 I.U. T.ni/mg of formulated product. PLUS, larvae begin to move slowly, become discolored, shrivel and blacken prior death. End-use product acts by ingestion against Lepidopteran larvae. CROPS, APPLICATION RATES AND DIRECTION FOR USE CAUTION HANDLE WITH CARE FRUIT CROPS - Pome fruits (apple, pear, quince): Tortricid moths (Argyrotaenia spp., Pandemis spp., Archips PRECAUTIONARY STATEMENTS: podana, Adoxophyes orana), Rusty tussock moth (Orgyia antiqua), Quince moth (Euzophera P102: Keep out of reach of children. bigella) 0.75 - 1.5 Kg/ha, with water volume of 600-1500 L/ha. P260: Do not breathe spray. - Stone fruits (peach, nectarine, processing peach, apricot, plum, cherry): Oriental fruit moth P270: Do no eat, drink or smoke when using this product. (Cydia molesta), Peach twig borer (Anarsia lineatella) 0.75 - 1.5 Kg/ha, with water volume of 600- P271: Use only outdoors or in a well-ventilated area. 1500 L/ha. - Kiwifruit: Grape tortrix moth (Argyrotaenia pulchellana), Copper underwing moth (Amphipyra SUPPLEMENTARY STATEMENTS: pyramidea) 0.75 - 1.5 Kg/ha, with water volume of 600-1500 L/ha. EUH401: To avoid risks to human health and the environment, comply with the instructions for use. SP1: Do not contaminate water with product or its container. GRAPE VINE AND TABLE GRAPE: Grape berry moths (Eupoecilia ambiguella, Lobesia Contains Bacillus thuringiensis subspecies kurstaki strain EG2348. Micro-organisms may have the botrana) 0.75 - 1.5 Kg/ha, with water volume of 100-1500 L/ha. potential to provoke sensitizing reactions. Wear protective clothing for biological agents, classified as personal protective equipment with related VEGETABLES EC marking for protection against biological agents, and gloves, such as personal protective - Cabbages (cauliflower, broccoli, savoy cabbage, head cabbage, Chinese cabbage, Brussels equipment with relevant EC marking and with compliance to EN 374. sprouts, turnip cabbage): Large (cabbage) white (Pieris brassicae), Noctuid moths (Spodoptera littoralis), Diamond back moth (Plutella xylostella) 0.75 - 1.5 Kg/ha, with water volume of 500- REGISTRATION HOLDER 1500 L/ha; Cabbage moth (Mamestra brassicae) 1 - 1.5 Kg/ha, with water volume of 500-1500 CBC (Europe) S.r.l. L/ha. Via E. Majorana, 2 - 20834 Nova Milanese (MB) - Tel. 0362 - 365079 Open field and protected use. - Artichoke: Artichoke moth (Gortyna xanthenes) 0.75 - 1.5 Kg/ha, with water volume of 500- MANUFACTURING PLANTS (PRODUCTION AND PACKING) 1500 L/ha. Sinapak S.r.l. - Via dell’Industria e dell’Artigianato, 7 - 27049 Stradella (PV) - Leaf vegetables (lettuce, chicory, endive, radicchio, escarole, garden rocket, corn salad, spinach, S.T.I. Solfotecnica Italiana S.p.A.- Via Evangelista Torricelli, 2 - 48010 Cotignola (RA) leaf beet and chard, cardoon, celery, fennel, parsley, chive, basil): Noctuid moths (Spodoptera littoralis, Helicoverpa armigera, Chrysodeixis chalcites) 0.75 - 1.5 Kg/ha, with water volume of Registration n. 12888 of 17.01.2007 by Ministry of Health 500-1000 L/ha. Open field and protected use. Net weight: 0.5 - 1 kg - Bean and French bean: Noctuid moth (Helicoverpa armigera) 0.75 - 1.5 Kg/ha, with water volume of 500-1000 L/ha. Batch n. _______________ Production date ________________ Open field and protected use. - Cucurbits (water melon, melon, pumpkin, courgette, cucumber): Noctuid moths (Spodoptera LEPINOX® PLUS is a trademark of CBC (Europe) S.r.l. littoralis, Helicoverpa armigera) 0.75 - 1.5 Kg/ha, with water volume 600-1500 L/ha. Open field and protected use. Rev. 1215 Label authorized by official decree dated 19/01/2016 - Solanaceous fruits (tomato, aubergine, sweet pepper): Noctuid moths (Spodoptera littoralis, PRE-HARVEST INTERVAL: NOT RELEVANT Spodoptera exigua), Tomato leafminer (Tuta absoluta) 0.75 - 1.5 Kg/ha, with water volume of 500-1500 L/ha; Cotton bollworm (Helicoverpa armigera), Cabbage moth (Mamestra brassicae, WARNING: When mixed with other plant protection products, the longest waiting period should Mamestra olearacea) 1 - 1.5 Kg/ha, with water volume of 500-1500 L/ha. be respected. Follow safety directions for dangerous products. In case of intoxication, inform Open field and protected use. doctors about the mixing done. STRAWBERRY: Noctuid moths (Spodoptera littoralis) 0.75 - 1.5 Kg/ha, with water volume of WARNING 500-1500 L/ha. Intended for agricultural usage only, it is dangerous for other purposes. Open field and protected use. The responsibility of using the product remain to the end user. All direction of use should be followed in order to ensure the proper use of the product, as well as FLOWERS AND ORNAMENTALS: Noctuid moths 0.75 - 1.5 Kg/ha, with water volume of 600- the security and health of treated crops, persons and protection of the environment. 1500 L/ha. Do not apply with aircraft. Open field and protected use. Do not apply against the wind. For end use only. HOP: European corn borer (Ostrinia nubilalis) 0.75 - 1.5 Kg/ha, with water volume of 600-1500 Dispose empty container according to local regulation. L/ha. Avoid contamination of the environment by empty containers. Do not reuse empty container. COTTON, TOBACCO: Cotton bollworm (Helicoverpa armigera) 1 - 1.5 Kg/ha, with water volume of 500-1500 L/ha. st Apply at hatched eggs and young larvae stages (1 stage). Repeat treatments after 7 - 10 days if the critical period (i.e.