CURRICULUM VITAE FOR ACADEMIC PROMOTION The Johns Hopkins University School of Medicine Larry William Chang, MD, MPH (Signature) _____________________________ July 2, 2014 (Typed Name) Larry William Chang (Date of this version) DEMOGRAPHIC AND PERSONAL INFORMATION Current Primary Appointment Assistant Professor Division of Infectious Diseases, Department of Medicine Johns Hopkins University School of Medicine Baltimore, MD Joint Appointments Social and Behavioral Interventions Program, Department of International Health Johns Hopkins Bloomberg School of Public Health Baltimore, MD Department of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore, MD Personal Data Business Address 725 N. Wolfe Street, Suite 216 Baltimore, MD 21205 Phone: (410) 929-2001 Fax: (410) 685-0031 E-mail: [email protected] EDUCATION AND TRAINING Undergraduate 1997 B.A., English Emory University, Atlanta, GA 1997 B.A., Biology Emory University, Atlanta, GA Doctoral/graduate 2002 M.P.H., Epidemiology Emory University Rollins School of Public Health, Atlanta, GA 2002 M.D., Medicine Emory University School of Medicine, Atlanta, GA Postdoctoral 2002-2005 Internship/Residency University of California, San Francisco, San Francisco, CA 2006-2009 I.D. Fellowship Johns Hopkins School of Medicine, Baltimore, MD PROFESSIONAL EXPERIENCE Dates Positions and Institutions 2002-2003 Categorical Internal Medicine Intern, Department of Medicine, University of California, San Francisco, San Francisco, CA 2003-2005 Categorical Internal Medicine Resident, Department of Medicine, University of California, San Francisco, San Francisco, CA 2004-2005 Hospitalist Physician, IPC—The Hospitalist Company, Doctor’s Medical Center, San Pablo, CA 2005-2006 Lead Research Analyst and Coordinator, Cochrane HIV/AIDS Group, Institute of Global Health, University of California, San Francisco for the World Health Organization Conference: Creating guidelines on essential prevention and care interventions for adults and adolescents living with HIV in resource-limited settings 2006-2009 Fellow in Infectious Diseases, Department of Medicine, Johns Hopkins University, Baltimore, MD 2009-2010 Instructor, Division of Infectious Diseases, Department of Medicine, Johns Hopkins University, Baltimore, MD 2009-Present Research Faculty, Center for Clinical Global Health Education (CCGHE), Johns Hopkins University, Baltimore, MD 2009-Present Active Staff, John Hopkins Hospital, Baltimore, MD 2010-Present Assistant Professor, Division of Infectious Diseases, Department of Medicine, Johns Hopkins University, Baltimore, MD 2012-Present Assistant Professor, Social and Behavioral Interventions Program, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 2013-Present Assistant Professor, Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 2013-Present Associate Director, Johns Hopkins University Global mHealth Initiative RESEARCH ACTIVITIES My primary research focus is HIV implementation science, specifically how to best implement HIV/AIDS engagement and care interventions (e.g. antiretroviral therapy) in resource-constrained settings. I have conducted randomized-controlled trials, observational studies, and systematic reviews in this field. A related research area of mine is mHealth (mobile health technology) strategies for improving global health and clinical care. My research is multidisciplinary, using mixed methods (quantitative and qualitative), and integrating behavioral science and economic evaluations with patient-oriented outcomes research. Peer-Reviewed Publications 1. Aberg JA, Watson J, Segal M, Chang LW. Clinical utility of monitoring serum cryptococcal antigen (sCRAG) titers in patients with AIDS-related cryptococcal disease. HIV Clinical Trials 2000;1:1-6. 2. Chang LW, Osei-Kwasi M, Boakye D, Aidoo S, Hagy A, Curran JW, Vermund SH. HIV-1 and HIV-2 Seroprevalence and risk factors among hospital outpatients in the Eastern Region of Ghana, West Africa. JAIDS 2002;29:511-516. 3. Macharia DK, Chang LW, Lule G, Owili DM, Tesfaledet G, Patel S, Silverstein DM, Ng’ang’a L, Bush T, De Cock KM, Weidle PJ. Antiretroviral therapy in the private sector of Nairobi, Kenya: a review of the experience of five physicians. AIDS 2003;17(6):938-940. 4. Chang LW, Phipps WP, Kennedy GF, Rutherford GW. Antifungal interventions for the primary prevention of cryptococcal disease in adults with HIV. Cochrane Database Syst Rev 2005;Jul 20(3):CD004773. 5. Chang LW, Vidyarthi AR, Kohlwes RJ. Baseline duty hours recorded with time-cards: a pre- regulation study of internal medicine residents. Medical Education 2006;40(7):662-667. 6. Chang LW, Kagaayi J, Nakigozi G, Galiwango R, Mulamba J, Ruwangula A, Gray RH, Quinn TC, Bollinger RC, Reynolds SJ. Telecommunications and health care: An HIV/AIDS Warmline for communication and consultation in Rakai, Uganda. J Int Assoc Physicians AIDS Care 2008;7(3):130- 132. PMCID: PMC2674571 7. Chang LW, Slamo S, Guma S, Christopher J, Suntoke T, Omeste R, Montis J, Quinn T, Juncker M, Reynolds SJ. Two year virologic outcomes of an alternative AIDS care model: evaluation of a peer health worker and nurse-staffed community-based program in Uganda. JAIDS 2009;50:276-282. PMCID: PMC2662625 8. Chang LW, Kennedy CE, Kennedy GE, Lindegren ML, Marston BJ, Kaplan JE, Sweat MD, Bunnell RE, O’Reilly K, Rutherford GW, Mermin JH. Developing WHO guidelines with pragmatic, structured, evidence-based processes: a case study. Global Public Health 2010;5(4):395-412. 9. Chang LW, Harris J, Humphreys E. Optimal monitoring strategies for guiding when to switch first-line antiretroviral therapy regimens for treatment failure among adults and adolescents living with HIV in low-resource settings. Cochrane Database Syst Rev 2010;Apr 13(4):CD008494. 10. Chang LW, Kagaayi J, Nakigozi G, Ssempijja V, Packer A, Serwadda D, Quinn TC, Gray RH, Bollinger RC, Reynolds SJ. Effect of Peer Health Workers on AIDS Care in Rakai, Uganda: a Cluster-Randomized Trial. PLoS ONE 2010;5(6):e10923. PMCID: PMC2880005 11. Humphreys EH, Chang LW, Harris J. Antiretroviral regimens for patients with HIV who fail first-line antiretroviral therapy. Cochrane Database Syst Rev 2010; Jun 16(6):CD006517. 12. Chang LW, Kaye D, Muhwezi WW, Nabirye RC, Mbalinda S, Okullo I, Groves S, Kennedy CE, Bollinger RC, Sisson S, Burnham G, Mwanika A. Perceptions and Valuation of a Community-Based Education and Service (COBES) Program in Uganda. Medical Teacher 2011;33:e9-e15. 13. Kaye D, Mwanika A, Burnham G, Chang LW, Mbalinda S, Okullo I, Nabirye RC, Muhwezi W, Oria H, Kijjambu S, Atuyambe L, Aryeija W. The organization and implementation of community-based education programs for health worker training institutions in Uganda. BMC International Health and Human Rights 2011;11(Suppl 1):S4. PMCID: PMC3059476 14. Mwanika A, Okullo I, Kaye D, Muhwezi W, Atuyambe L, Nabirye RC, Groves S., Mbalinda S, Burnham G, Chang LW, Oria H, Sewankambo N. Perception and valuations of community-based education and service by alumni at Makerere University College of Health Sciences. BMC International Health and Human Rights 2011;11(Suppl 1):S5. PMCID: PMC3059477 15. Arem H*, Nakyanjo N, Kagaayi J, Mulamba J, Nakigozi G, Serwadda D, Quinn TC, Gray RH, Bollinger RC, Reynolds SJ, Chang LW. Peer Health Workers and AIDS Care in Rakai, Uganda: a Mixed Methods Operations Research Evaluation of a Cluster-Randomized Trial. AIDS Patient Care and STDs 2011;25(12):719-724. PMCID: PMC3216066 16. Chang LW, Kagaayi J, Arem H*, Nakigozi G, Ssempijja V, Serwadda D, Quinn TC, Gray RH, Bollinger RC, Reynolds SJ. Impact of a mHealth Intervention for Peer Health Workers on AIDS Care in Rural Uganda: a Mixed Methods Evaluation of a Cluster-Randomized Trial. AIDS and Behavior 2011;15:1776-1784. PMCID: PMC3265752. 17. Njie-Carr V*, Kalenge S, Kelley J, Wilson A, Muliira JK, Nabirye RC, Glass N, Bollinger RC, Alamo- Talisun S, Chang LW. Research Capacity Building Program for Clinicians and Staff at a Community- Based HIV/AIDS Clinic in Uganda: A Pre/Post Evaluation. Journal of the Association of Nurses in AIDS Care 2012;23:431-441. PMCID: PMC3875907. 18. Chang LW, Mwanika A, Kaye D, Muhwezi W, Nabirye RC, Mbalinda S, Okullo I, Kennedy CE Groves S, Sisson SD, Burnham G, Bollinger RC. Information and communication technology and community-based health sciences training in Uganda: perceptions and experiences of educators and students. Informatics for Health and Social Care 2012;37(1):1-11. PMC Journal - In Process 19. Thompson MA, Mugavero MJ, Amico KR, Cargill VA, Chang LW, Gross R, Orrell C, Altice FL, Bangsberg DR, Bartlett JG, Beckwith CG, Dowshen N, Gordon CM, Horn T, Kumar P, Scott JD, Stirratt MJ, Remien RH, Simoni JM, Nachega JB. Guidelines for Improving Entry Into and Retention in Care and Antiretroviral Adherence for Persons With HIV: Evidence-Based Recommendations From an International Association of Physicians in AIDS Care Panel. Annals of Internal Medicine 2012;156:817-833. 20. Chang LW, Kadam DB, Sangle S, Narayanan S, Borse RT, McKenzie-White J, Bowen CW, Sisson SD, Bollinger RC. Evaluation of a Multimodal, Distance Learning HIV Management Course for Clinical Care Providers in India. J Int Assoc Physicians AIDS Care 2012;11(5):277-82. PMCID: PMC3856228. 21. H Tumwebaze, Tumwesigye E, Baeten JM, Kurth AE, Revall J, Murnane PM, Chang LW, Celum C. Household-based HIV counseling and testing as a platform for targeted referral to HIV care and medical male circumcision in Uganda: a pilot