<p>DNA: A Summary of Important Historical Discoveries Bio 12 Allen</p><p>Outcomes addressed: (315-1) summarize the main scientific discoveries that led to the modern concept of the gene (114-2) explain the role of evidence, theories, and paradigms in the development of this scientific knowledge (115-3) explain how a major scientific milestone revolutionized thinking in the scientific communities </p><p>Using your notes and text, complete the cart below Scientist(s) year brief summary of experiment (if details are Conclusions made from experiment available to you)</p><p>Friedrich 1869 Miescher</p><p>Walter Sutton 1902</p><p>Thomas Hunt 1910 Morgan</p><p>Joachim 1930 Hammerling </p><p>Frederick 1931 • Griffith</p><p>Oswald Avery 1944 & associates</p><p>Hershey & 1952 • Chase</p><p>DNA: A Summary of Important Historical Discoveries Bio 12 Allen Using your notes and text, complete the cart below</p><p>Scientist(s) year brief summary of experiment (if details are Conclusions made from experiment available to you)</p><p>Friedrich 1869 Isolated the nuclei from pus cells nuclein  rich in phosphorus, contained no Miescher • Discovered a chemical that didn`t act sulfur (so it wasn’t protein) like protein. He named it “nuclein”</p><p>Walter Sutton 1902 observed that chromosomes obey Mendel's rules of inheritance -Suggested that “genes” are located on chromosomes. Noticed that “genes” are inherited in the same fashion as chromosomes Thomas Hunt 1910 Stated that each “gene” had a locus on a Morgan particular chromosome</p><p>Joachim 1930 Studied Acetabularia. Cut off foot/stalk hereditary information is localized to nuclei Hammerling </p><p>Frederick 1931 • Injected mice with smooth virulent and Coined the term, ‘transforming principle”. Griffith rough avirulent strains of bacteria.</p><p>Oswald Avery 1944 • experiment led Avery to design his own Results suggested that DNA was the & associates experiments to identify the “transforming transforming agent agent.” Enzymes that degrade proteins and RNA did not prevent transformation. Enzymes that digest DNA did prevent transformation. Hershey & 1952 • grew two batches of phages in DNA is the genetic information. NOT protein Chase radioactive sulfur/phosphorous</p>