<p>Table S5. Overlap of the gene lists for contrasts. The numbers above the diagonal denote the overlapping genes between lists, below the diagonal are P-values, and at the diagonal is the number of unique genes in the lists. Genes responding to aging in control lines at day 19 (AC19) and 35 (AC35); genes responding to aging in longevity-selected lines at day 19 (ALS19), 35 </p><p>(ALS35), and ≥ 60 (ALS60); genes responding to selection for increased longevity at the same chronological age at day 3 (Ch3), </p><p>19 (Ch19), and 35 (Ch35); genes responding to selection for increased longevity at the same physiological age at days 3-19 (P3), </p><p>19-35 (P19), and 35-60 (P35); the overlap between the genes responding to selection at the same chronological and physiological age (OL).</p><p>AC19 AL19 Ch3 P3 AC35 AL35 Ch19 P19 AL60 Ch35 P35 OL AC19 267 160 0 0 73 24 7 2 30 13 4 1 AL19 <0.0001 259 3 0 57 17 1 2 36 6 2 0 Ch3 NS NS 125 20 4 4 55 8 2 93 10 25 P3 NS NS <0.0001 23 0 0 17 8 1 15 8 20 AC35 <0.0001 <0.0001 NS NS 269 56 5 3 29 16 3 1 AL35 <0.0001 <0.0001 <0.01 NS <0.0001 88 3 4 14 3 2 0 Ch19 <0.01 NS <0.0001 <0.0001 <0.05 <0.01 99 12 3 77 13 28 P19 <0.05 <0.05 <0.0001 <0.0001 <0.01 <0.0001 <0.0001 38 0 13 15 17 AL60 <0.0001 <0.0001 NS NS <0.0001 <0.0001 NS NS 290 53 3 1 Ch35 NS NS <0.0001 <0.0001 <0.05 NS <0.0001 <0.0001 <0.0001 486 18 32 P35 <0.01 NS <0.0001 <0.0001 <0.05 <0.01 <0.0001 <0.0001 <0.05 <0.0001 50 22 OL NS NS <0.0001 <0.0001 NS NS <0.0001 <0.0001 NS <0.0001 <0.0001 40</p>