<p>MLAB 1227 Coagulation</p><p>Coagulation Disorders: Primary Hemostasis</p><p>Learning Objectives</p><p>At the end of this unit, the student should be able to:</p><p>1. Explain the pathophysiologic processes that cause thrombocytopenia.</p><p>2. List specific thrombocytopenic disorders caused by each process.</p><p>3. Compare ITP and thrombocytopenic purpura (TTP).</p><p>4. Discuss the characteristics of the inherited platelet membrane defects.</p><p>5. Summarize the differences between Bernard-Soulier syndrome and Glanzmann’s thrombasthenia.</p><p>6. Differentiate among the vascular disorders associated with purpura.</p><p>7. Define the terms thrombocytopenia and thrombocytosis.</p><p>8. Name the acquired coagulation disorders.</p><p>9. Define and differentiate between petechiae, purpura, ecchymosis and hematoma.</p><p>10. Identify laboratory tests that can be ordered to screen for abnormalities of the hemostatic system.</p><p>11. Explain the expected clinical outcomes when a patient has an abnormality of platelets or blood vessels.</p><p>12. Distinguish between primary and secondary(reactive) thrombocytosis.</p><p>13. Explain the effect of aspirin and its duration on platelet function.</p><p>14. Predict the type of bleeding symptoms in patients with disorders of primary hemostasis.</p><p>4/5/2018 MLAB 1227 Coagulation</p><p>15. Estimate the percentage of circulating platelets found in the spleen.</p><p>16. Identify expected laboratory results in patients with ITP.</p><p>17. Cite an example of a drug that causes thrombocytopenia.</p><p>4/5/2018</p>