
<p> Bartlett 2005 Basad 2004 Bentley 2003 Dozin 2005 Gooding 2006 Horas 2003 Knutsen 2004 Knutsen 2007 Saris 2008 Saris 2009 Visna 2004 ACI-C MACI MACI MF ACI MP ACI-P MP ACI-P ACI-C ACI-P MP ACI-P MF ACI-P MF CCI MF CCI MF ACT abration N 44 47 10 9 58 42 22 22 33 35 20 20 40 40 40 40 57 61 57 61 25 25 s</p><p> h 59/6, t 51/6,12 n</p><p> o Clinical 44/12 47/12 58/12 42/12 19/10 18/10 33/24 35/24 40/3,6,12,24 80/12,24 80/60 57/12, 39/36 43/36 25/12 25/12 44/18 m</p><p>/ 51/18</p><p> s</p><p> r Arthrosc 31/12 29/12 e</p><p> t 24/12 18/12 37/12 23/12 77/24 4/3-5 e</p><p> l opy 9/24 11/24 p 14/12 13/12 m Biopsy 14/12 11/12 19/12 6 5 32/24 35/24 25/12 38/12 o</p><p> c 3/24 7/24 14/12 13/12 pre 14/12 11/12 19/12 24.9 28.45 57.4 55.4 47.6 52.6 3/24 7/24</p><p>5 m 1 l , o 0</p><p>2 27.6/3 28/3,53.5/6 77.2/5 , h 1 78/12 </p><p>0 s , 45.8/6 68.3/12 69.2/12 86.5/12 69.2/5 5 y 5</p><p> post +48 +15 75.4/24 p= 0.23 9 L ,</p><p>2 57.5/12 72.7/24 70.8/24 p<0.001/1 74.5/12 1 . p=0.092 * 0 66.8/24 p<0.05/all 2 = p pre 1.6 1.6 3.28 3.16 3.2** 2.3***</p><p> r e</p><p> n 1.6/3, 3.6/6</p><p> g 1.6/3, 3/6, 4.36/60 6/12 </p><p> e post +1.6 +0 5/6, 5.2/24 4.05/60 4.2/12</p><p>T 4.3/6, 5.1/24 p=0.3 p<0.01 p>0.05 15,19,7, Modified 10,16,10 23,28,7,0 10,12,7,4/ 12,14,5,4 6 9,20,6,7 Cincinnati ,8 p$=0.28 12 p$>0.05/12 p$=0.32 pre 53.9 53.7</p><p>S 40.3/12 A 35.5/12</p><p>V post -1.7 -1.9 35.2/24 p=0.278 31.3/24 p=0.292 pre 7.2 7.85 s</p><p> r 7.9/3, 3.8/6, e 8.5/3, 12.1/6, y 15.9/12, a post + 6.5 +1.9 4.2/12,</p><p>M 16.8/24 15.9/24 p>0.05</p><p> d pre 56.3 59.5 e S i f i O 70.6/6, 72.6/6, +21.25 +15.8 d O o post 73.3/12, 73.10/12, p=0.05 K M 74.7/18 75/18 pre 41.1 37.4 6 3</p><p>- 42.9/12,</p><p>F 42.6/12,</p><p>S post 46/24 P=0.054 42/24 p=0.004</p><p>0 , 2 2 5 l 4 4 , 1 l 1 / / 2 2 a 5 / / / 1 1 S 1 1 , , 1 0 , , 5</p><p>, , 9.1/12</p><p> . R 5 5 4 5 , ,</p><p>6,24,6,1 0,8,10,5 3 2</p><p> post , 0 8.1/12 $ 8.5 , , C 2 0 8 3 I</p><p>> p =0.170</p><p>$ 5 8 , . 2 2 $ , , p <0.01 , , 4 0 p 0 1 3 3 = $ p hyaline like 4/12 3/12 7/12 2/12, 1/24 3/12, 1/24 6/24 4/24 y</p><p> s mixed 2/12 1/12 7/12 4/12, 2/24 6/12, 4/24 10/24 6/24 p o i Fibro</p><p>B 8/12 7/12 5/12 8/12, 0/24 4/12, 2/24 11/24 18/24 cartilage Fibrous 5/24 7/24 pre 41.3 45 C</p><p>D 67/5,76.5/12 62.3/5,</p><p>K post I p<0.05/12 68.1/12 Stanmore post -0.8 -0.6 Appendix Table. Data as reported in studies included in the review. The mean values at each follow-up in months are reported (mean/months) for Lysholm, Tegner, VAS, Mayers, KOOS, SF-36, ICRS, IKDC and Stanmore scores. For biopsies counts/months are reported. Cincinatti score and ICRS in three studies are reported as number of participants in categories excellent, good, fair, poor. P-values refer to comparisons between arms and are printed in the arm they favour. </p><p>* Number of patients in each group according to Lysholn score, with cutpoints 60 and 90 units ** retrospectively measured at 12 patients ***retrospectively measured at 10 patients Modified Cincinnati is classified as excellent, good, fair, and poor and refers to postoperative values only. Similarly for ICRS in three trials. $ p values refer to comparison between good or excellent group versus fair and poor. Estimated from four patients only</p>
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