<p>Surveillance of spontaneous breast cancer metastasis by TRAIL-expressing CD34+ cells in a xenograft model</p><p>Breast Cancer Research and Treatment</p><p>Anna Rossini, Marta Giussani, Arianna Giacomini, Carla Guarnotta, Elda Tagliabue and 1,2Andrea Balsari</p><p>1Dipartimento di Scienze biomediche per la salute, Università di Milano, Italy, 2Molecular Targeting Unit, Department of Experimental Oncology, Fondazione IRCCS – Istituto Nazionale dei Tumori, 20133 Milano, Italy.</p><p>Corresponding author: Prof. Andrea Balsari, Dipartimento di Scienze biomediche per la salute, Via</p><p>Mangiagalli 31, Milano, Italia. Phone number: +39-02-23902564; FAX number: +39-02-23902692; E- mail: [email protected] Supplemental Table 1</p><p>Sensitivity to CD34-TRAIL+ cells and soluble TRAIL in breast cancer cell lines</p><p>Cell death (%)</p><p>Cell line Soluble TRAIL CD34-TRAIL+ cells l a MDA-MD-231 25.8±1.6* 43.5±3.6 m y h c n</p><p> e MDA-MD-157 31.1±3.1 56.7±3.6 s e m</p><p>N SUM-159 72.5±8.8 75.0±4.8 T l a s</p><p> a MDA-MD-468 6.2±3.9 27.7±2.2 b</p><p>N T HCC-1937 9.1±4.6 45.6±8.9 l a n i ZR-75-1 4.5±3.5 44.0±5.5 m u l</p><p>+</p><p>R T47D 3.8±3.8 33.0±2.8 E</p><p>MCF7 1.6±1.5 28.5±12.2</p><p>BT-474 1.6±1.6 7.9±1.2</p><p>MDA-MD-361 0.4±0.3 0.1±0.1 + 2</p><p>R SKBR3 7.2±4.2 42.7±13.4 E H MDA-MD-453 0.47±0.4 13.8±0.5</p><p>*Data, given as mean +/- S.E.M. in 3 independent experiments, represent the percentage of soluble TRAIL and CD34- TRAIL+cell cytotoxicity corrected for that of untreated and non-transfected CD34+ cells, respectively.</p>