<p>Obesity in pediatric kidney transplant recipients and the risks of acute rejection, graft loss and death.</p><p>Maleeka Ladhani MPH1,2</p><p>Samantha Lade MBBS3 </p><p>Stephen I Alexander PhD1,4</p><p>Louise A Baur PhD1,4</p><p>Philip A Clayton PhD5</p><p>Stephen McDonald PhD5</p><p>Jonathan C Craig PhD1,2,4</p><p>Germaine Wong PhD1,2,6</p><p>Affiliations:</p><p>1 Sydney School of Public Health, University of Sydney</p><p>2 Centre for Kidney Research, The Children’s Hospital at Westmead</p><p>3 Department of General Medicine, The Children’s Hospital at Westmead</p><p>4 The Children’s Hospital at Westmead Clinical School, University of Sydney</p><p>5 ANZDATA Registry SA Health & Medical Research Institute, Adelaide & </p><p>Faculty of Health Sciences, University of Adelaide</p><p>6 Centre for Renal and Transplant Research, Westmead Hospital, NSW, </p><p>Australia</p><p>Correspondence: </p><p>Dr Maleeka Ladhani,</p><p>C/- Centre for Kidney Research, Children's Hospital at Westmead,</p><p>Westmead NSW 2145 Australia</p><p>Email: [email protected] Tel no: +61 411 332 456 eTable 1: Univariate and multivariate hazard ratios for patient survival, graft survival and acute rejection within 6 months</p><p>Univariate Multivariate Acute rejection N = 628 (102) N = 628 (102) Underweight 1.04 (0.53, 2.03) 1.07 (0.54, 2.09) Normal weight 1 1 Overweight 1.26 (0.77, 2.08) 1.42 (0.86, 2.34) Obesity 1.48 (0.78, 2.81) 1.83 (0.95, 3.51) Graft survival N = 750 (235) N = 733 (235) Underweight 1.26 (0.84, 1.91) 1.05 (0.70, 1.60) Normal weight 1 1 Overweight 0.96 (0.67, 1.38) 1.03 (0.71, 1.49) Obesity 1.46 (0.96, 2.23) 1.61 (1.05, 2.47)* Patient survival N = 750 (53) N = 738 (53) Underweight 1.51 (0.70, 3.26) 1.18 (0.54, 2.58) Normal weight 1 1 Overweight 0.78 (0.35, 1.77) 0.85 (0.38, 1.92) Obesity 0.66 (0.20, 2.16) 0.80 (0.25, 2.61)</p><p>N = Number of patients (number of events) * p=0.03</p>