<p>The Central Dogma Dry Lab</p><p>Following is the base sequence of a gene on one strand of a DNA molecule (the SENSE STRAND):</p><p>A A T G C C A G T G G T T C G C A C</p><p>1. What is the sequence of the complementary DNA strand (i.e. the NONSENSE STRAND)?</p><p>2. What is the sequence of the mRNA transcribed from this gene?</p><p>3. Use the provided genetic code, to determine what amino acids will be in the protein coded for by this gene.</p><p>4. If the fourth nucleotide in the original DNA strand was changed from G to C, what sequence of mRNA would result? i.e., the DNA sequence is now A A T C C C A G T G G T T C G C A C</p><p>5. What sequence of amino acids would this code for?</p><p>6. If a G were added to the original DNA strand after the third nucleotide, what sequence of mRNA would result? i.e., the DNA sequence is now A A T G G C C A G T G G T T C G C A C</p><p>7. What sequence of amino acids would this code for?</p><p>8. If the eighth nucleotide in the original DNA strand was changed from a G to a C, what mRNA sequence would result? i.e., the DNA sequence is now A A T G C C A C T G G T T C G C A C</p><p>9. What sequence of amino acids would this code for? Why is this sequence so short? Second mRNA Base U C A G t s U phenylalanine Serine Tyrosine Cysteine U r i</p><p>F phenylalanine Serine Tyrosine Cysteine C A</p><p>N leucine Serine STOP STOP A R</p><p> m leucine Serine STOP tryptophan G e s a</p><p>C leucine proline Histidine arginine U T B h</p><p> leucine proline Histidine arginine C i r d</p><p> leucine proline Glutamine arginine A m</p><p> leucine proline Glutamine arginine G R N</p><p>A isoleucine threonine Aspragine serine U A</p><p>B</p><p> isoleucine threonine Asparagines serine C a s isoleucine threonine Lysine arginine A e Methionine (start) threonine Lysine arginine G G valine alanine Aspartic acid glycine U valine alanine Asprartic acid glycine C valine alanine Glutamic acid glycine A valine alanine Glutamic acid glycine G</p>
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