<p> Name______Date______Period______Genetic Technology WebQuest</p><p>LinkLink #1 #1: http://www.ornl.gov/sci/techresources/Human_Geno me/home.shtml 1. When was the Human Genome Project completed?</p><p>2. Fill in the blanks that address the goals of the human genome project:  identify all the approximately ______genes in human DNA,  determine the sequences of the ______chemical base pairs that make up human DNA,  store this information in ______,  improve tools for ______,  transfer related technologies to the ______,  Address the ______(ELSI) that may arise from the project.  Link #2: http://www.vtaide.com/png/cloning.htm  Central Dogma of Biochemistry 3.Link Finish #2 this sentence: The central theme underlying all of biochemistry is that…</p><p>4. Which molecule serves as an intermediate between a gene and a protein?</p><p>Link #3 Link #3: Go http://learn.genetics.utah.edu/content/cloning/clickandclone/ (If this link doesn’t work- you can Google “Mimi the Mouse” and it is the first link). 5. What are you asked to remove from the egg?</p><p>6. What are you asked to remove from the somatic cell?</p><p>7. Where are you asked to put the nucleus from the somatic cell?</p><p>8. How is Mimi involved in the process of cloning Mimi?</p><p>9. What color is the baby mouse (pup)?</p><p>10. When and where was this procedure used in science? What did scientists learn from their research?</p><p>LinkLink #4 #4 Go back to http://www.medicalnewstoday.com/info/stem_cell/ Name______Date______Period______</p><p>11. Where are stem cells?</p><p>12. What are the two types of stem cells and what are the differences between them?</p><p>LinkLink #5 #6: http://www.dnai.org/d/index.html  DNA Applications  Human Application Click on “Profiling”</p><p>15. List some places you could take a DNA sample from.</p><p>Click on “Family” 16. Describe the first practical test of DNA fingerprinting.</p><p>Go through the slides, click on A: Try the comparison. </p><p>17. What was the outcome of this case?</p><p> Click on the “Murder” Read the case of the state of Florida vs. Jones and Reesh, Murder at Rodman Dam, 1988</p><p>18. Click on Letter A to match the fingerprints yourself. Who raped Perry?</p><p>LinkLink #6 #7: http://learn.genetics.utah.edu/content/labs/gel/ Continue to click through the animation to answer the following questions. 19. What does the liquid contain?</p><p>20. How can we sort the DNA samples even though we can’t see them?</p><p>21. How can we make DNA move through the gel? 22. What kind of charge is on the end with the wells? ______</p><p>23. What size strands move most quickly through the gel?</p><p>24. What shows up as bands in the gel? Now it’s your turn… Name______Date______Period______</p><p>25. What are the 5 steps to making a gel electrophoresis? (Hint: look at the top right of the screen).</p><p>26. What is needed to make the gel?</p><p>27. What does the buffer do for the gel?</p><p>28. What forms the holes, or “wells” in gel?</p><p>29. Explain the purpose of putting the “DNA Standard” into one of the wells. </p><p>30. What kind of charge does DNA have?</p><p>31. What lets us know that the current is running through the gel?</p><p>32. What do we add to the DNA in order to see the bands?</p><p>33. How do we measure the estimated length of the bands?</p><p>33. What is you estimate for the size of the first band? Second band? Third band? Name______Date______Period______</p><p>LinkLink #7 #8: //http://www.csa.com/discoveryguides/gmfood/overview.php</p><p>34. Describe what “GM” means.</p><p>35. What is used to create GMOs?</p><p>36. . What were the two most harvested crops in America in 2000?</p><p>37. According to data taken in 2000, who was the leading producer of transgenic crops?</p><p>38. What are the possible outcomes (positive or negative) for using GMOs?</p><p>39. What do scientists predict are future transgenic crops and what is their purpose?</p><p>40. What percentage of cross contamination is accepted in GMO?</p><p>41. Out of all of the possible benefits to GM crops, 42. Out of all the possible controversies of GM </p><p> which three do you think are most important? crops, which three do you think are most </p><p> important?</p><p> </p><p> </p><p></p><p>Extra Credit:  Take “The Cloning Quiz” on the following link: http://www.vtaide.com/png/cloning.htm Score: ______ Try “Is it cloning or not?” from the following link: http://learn.genetics.utah.edu/content/tech/cloning/cloningornot/  How’d you do? OR  Go to http://www.ornl.gov/sci/techresources/Human_Geno me/home.shtml  Research  Gene Gateway  Genetic Disorder Guide  Genes and Disease. Look up the one of the following genetic disorders and briefly describe it below: (i.e. what causes it, how does it affect the individual, what is the mode of inheritance, can it be cured, etc).  List of Diseases to research: Hemophilia, muscular dystrophy, color blindness, Huntington’s, PKU, Tay-Sachs, Sickle Cell Anemia, and Cystic Fibrosis. </p>