<p> Microbiology Lecture 9: Microbial Pathogenesis</p><p>I. Microbial Pathogenesis a. Step I: Attachment b. Step II: Surviving Within the Host c. Step III: Deploying Toxins and Effectors</p><p>II. Attachment</p><p> a. Pili a.i. Type I</p><p> a.ii. Type III</p><p> a.iii. Type IV</p><p> b. Nonpilus Adhesins b.i. General Concepts</p><p> b.ii. MAM7</p><p> b.iii. Host Susceptibility</p><p> c. Biofilms and Infections</p><p>III. Surviving Within the Host a. Where am I?</p><p> b. Extracellular Immune Avoidance</p><p> c. Intracellular Pathogens d. Sleeping With The Enemy d.i. Molecular Mimicry</p><p> d.ii. Flipping Cytokine Profiles</p><p> d.iii. Stopping Programmed Cell Death</p><p> d.iv. Redirecting Host Ubiquitylation Signals</p><p>IV. Deploying Toxins and Effectors a. Exotoxins</p><p> a.i. Plasma Membrane Disruption</p><p> a.ii. Cytoskeleton Alterations</p><p> a.iii. Protein Synthesis Disruption</p><p> a.iv. Cell Cycle Disruption</p><p> a.v. Signal Transduction Disruption a.vi. Cell-Cell Adherence</p><p> a.vii. Vesicle Traffic</p><p> a.viii. Exocytosis</p><p> a.ix. Superantigens</p><p> b. Endotoxins </p>
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