I (X;Y) = S(X) - S(X|Y) in c ≈ p + N r V(t) = V0 + ∫dτZ 1(τ)I(t-τ) P(N) = V= R I 1 N! λ N e -λ www.cosyne.org R j = γ R = P( Ψ, υ) + M(Ψ, υ) σ n D n +∑ j k D n k WORKSHOPS Snowbird, UT Mar 3 - 4 ................................................................................................................................................................................................................. COSYNE 2014 Workshops Snowbird, UT Mar 3-4, 2014 Organizers: Tatyana Sharpee Robert Froemke 1 COSYNE 2014 Workshops March 3 & 4, 2014 Snowbird, Utah Monday, March 3, 2014 Organizer(s) Location 1. Computational psychiatry – Day 1 Q. Huys Wasatch A T. Maia 2. Information sampling in behavioral optimization – B. Averbeck Wasatch B Day 1 R.C. Wilson M. R. Nassar 3. Rogue states: Altered Dynamics of neural activity in C. O’Donnell Magpie A brain disorders T. Sejnowski 4. Scalable models for high dimensional neural data I. M. Park Superior A E. Archer J. Pillow 5. Homeostasis and self-regulation of developing J. Gjorgjieva White Pine circuits: From single neurons to networks M. Hennig 6. Theories of mammalian perception: Open and closed E. Ahissar Magpie B loop modes of brain-world interactions E. Assa 7. Noise correlations in the cortex: Quantification, J. Fiser Superior B origins, and functional significance M. Lengyel A. Pouget 8. Excitatory and inhibitory synaptic conductances: M. Lankarany Maybird Functional roles and inference methods T. Toyoizumi Workshop Co-Chairs Email Cell Robert Froemke, NYU [email protected] 510-703-5702 Tatyana Sharpee, Salk [email protected] 858-610-7424 Maps of Snowbird are at the end of this booklet (page 38). COSYNE 2014 Workshops March 3 & 4, 2014 Snowbird, Utah Tuesday, March 4, 2014 Organizer(s) Location 1. Computational psychiatry – Day 2 Q. Huys Wasatch A T. Maia 2. Information sampling in behavioral optimization – B. Averbeck Wasatch B Day 2 R.C. Wilson M. R. Nassar 3. Discovering structure in neural data E. Jonas Superior A S. Linderman R. Adams K. Körding 4. Thalamocortical network mechanisms for cortical M. Sherman Superior B functioning W. M. Usrey 5. Canonical circuits, canonical computations A. Disney Magpie A K. Padmanabhan 6. From the actome to the ethome: Systems A. Faisal Magpie B neuroscience of behavioral ecology C. Rothkopf 7. Sequence generation and timing signals in neural K. Rajan Maybird circuits C. D. Harvey D. W. Tank 8. Multisensory computations in the cortex J. Makin White Pine P. Sabes Workshop Co-Chairs Email Cell Rob Froemke, NYU [email protected] 510-703-5702 Tatyana Sharpee, Salk [email protected] 858-610-7424 Maps of Snowbird are at the end of this booklet (page 38). 3 Schedule Each workshop group will meet in two sessions from ~8–11 am and from 4:30–7:30 pm. Workshop summaries and schedules are available starting on page 3 of this booklet. Transportation Marriott Downtown to Snowbird: Free shuttle provided for registered attendees (first shuttle leaves @ 4pm, last @ 5pm on Sunday, 2 Mar 2014). Snowbird to Salt Lake City Airport: Shuttle can also be arranged at Snowbird, or online at: https://store.snowbird.com/ground_transport/ Further information about transportation to/from Snowbird is available at: http://www.snowbird.com/about/accessibility.html For further information on transportation or other logistics please contact Denise Soudan ([email protected]). Lift tickets Discounted workshop rates Snowbird Chairlifts only: $62 Snowbird Tram & Chairlifts: $72 Pick up at the Cliff ticket window (level 1 of the Cliff Lodge next to the ski rental shop) or at the ticket window on the top level of the Snowbird Center (the plaza deck). Meals included with registration Breakfast (Day 1 and Day 2) - The Cliff Ballroom Dinner (Day 2) - The Cliff Ballroom Coffee breaks during morning and afternoon sessions 5 1. Computational Psychiatry – Day 1 Monday, March 3, 2014 Organizers: Quentin Huys, ETH Zurich Tiago Maia Computational techniques have become increasingly important to neuroscience. Over the past few years, researchers have started to fruitfully apply such techniques to mental health, with applications in clinical practice now coming into reach. The approaches are fascinatingly diverse, spanning many imaging modalities, multiple levels of characterization of brain function and a vast array of computational and machine learning techniques. The workshop at Cosyne will bring together a large fraction of the key workers from across the spectrum of the field. Though nascent, computational psychiatry is a rapidly growing field and now is maybe the last opportunity for a reasonably comprehensive overview. Given the scope and breadth of questions and methods, such an overview is hard to fit into one day in a cohesive manner, and we have thus prepared a two-day workshop. It is important that this workshop should be held as part of Cosyne: it is one of the conferences with the most applicable broad technical skill sets for the problem at hand; the neuroscience of mental health is of genuine interest to the Cosyne community at large; and it is probably the main health sector to which insights gained in the Cosyne community can be applied. We hope to contribute to the consolidation of the field and the clarification of the key solvable questions by bringing together scientists using different techniques and working on different aspects of the same problem at this critical time of expansion. The first day will focus particularly on reinforcement learning and decision-making approaches, while the second day will broaden the scope and encompass work ranging from explicit neural network models to large-scale models of social interactions in psychiatric populations. 6 Computational Psychiatry – Day 1 Wasatch A Morning session Decision-making approaches 8:00–8:05 am Quentin Huys and Tiago Maia, Welcome and overview 8:05–8:45 am Martin Paulus, The utility of computational psychiatry 8:45–9:25 am Angela Yu, Learning and decision-making in inhibitory control 9:25–9:40 am Coffee break 9:40–10:20 am Quentin Huys. Decision-theoretic psychiatry Afternoon session Impulsivitty & Compulsivity 4:30–5:10 pm Tiago Maia, Reinforcement learning in avoidance, habits, and tics 5:10–5:50 pm Nathaniel Daw. Reinforcement learning and compulsion 5:50–6:10 pm Coffee break 6:10–6:35 pm Frederike Petzchner. Impulsive gambling 6:50–7:30 pm Valerie Voon. Recent studies in impulsivity and compulsivity across disorders of addiction. 7 2. Information Sampling in Behavioral Optimization – Day 1 Monday, March 3, 2014 Organizers: Bruno Averbeck, National Institutes of Mental Health Robert C. Wilson, Princeton Neuroscience Institute Matthew R. Nassar, University of Pennsylvania All learning depends on information - without information there is nothing to learn. But gathering information can be costly and the desire to learn can be opposed by the need for speed or the desire for immediate reward. In this workshop we will examine the role of information sampling in two well-known behavioral problems: the speed-accuracy tradeoff and the explore-exploit dilemma. We will hear from researchers studying these problems across a wide range of species, from monkeys and humans to rats and worms. We will look at information sampling algorithms that solve these problems optimally and the extent to which neural circuits and neuromodulators support these algorithms in the brain. Our aim is to bring together a diverse set of participants, from the usual reinforcement learning and decision making crowd, to researchers interested in foraging and theorists interested in algorithms. In the spirit of exploration, most of the talks will be given by non-faculty members -- i.e. postdocs and graduate students. We believe that this focus on the first authors, rather than the last, will not only provide a welcome forum for new voices, but will also encourage fresh perspectives on these classic problems. To highlight the similarity of the two behavioral problems, we will interleave talks on the explore-exploit dilemma with talks on the speed-accuracy tradeoff and several talks will combine both. 8 Information Sampling in Behavioral Optimization – Day 1 Wasatch B Morning session 8:30–9:00 am Robert Wilson, Human strategies for solving the exploration-exploitation dilemma 9:05–9:35 am Steven Flavell, Serotonin and the neuropeptide PDF initiate and extend opposing behavioral states in C. elegans 9:55–10:25 am Shunan Zhang, Forgetful Bayes and myopic planning: human exploration and exploitation in bandit problems 10:30–11:00 am Paul Schrater, Optimal exploration driven by reward statistics Afternoon session 4:30–5:00 pm Erie Boorman, Frontal polar cortex and the evidence for changing future behavior 5:05–5:35 pm Andra Geana, Reward, Risk and Ambiguity in Human Exploration - A Wheel of Fortune Task 5:55–6:25 pm Vincent Costa, Neural and Dopaminergic Contributions to Novelty Driven Choice Behavior 6:30–7:00 pm Matt Nassar, “Dissociating information value from information quantity 9 3. Rogue States: Altered Dynamics of Neural Circuit Activity in Brain Disorders Monday, March 3, 2014 Organizers: Cian O’Donnell and Terrence Sejnowski Salk Institute for Biological Studies Understanding and treating psychiatric and neurodevelopmental disorders such as schizophrenia, mood disorders, and autism is one of the central challenges for neuroscience research this century. Crucially, the devastating cognitive effects seen in these illnesses are likely the result of disruptions of neural circuit wiring and dynamics. Although these illnesses