VPS26A polyclonal antibody Gene Alias: FLJ12930, HB58, Hbeta58, PEP8A, VPS26 Gene Summary: This gene belongs to a group of Catalog Number: PAB6573 vacuolar protein sorting (VPS) genes. The encoded Regulatory Status: For research use only (RUO) protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde Product Description: Goat polyclonal antibody raised transport of proteins from endosomes to the trans-Golgi against synthetic peptide of VPS26A. network. The close structural similarity between the yeast and human proteins that make up this complex Immunogen: A synthetic peptide corresponding to suggests a similarity in function. Expression studies in human VPS26A. yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core Sequence: C-SPESQASAEQPEM of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms. Host: Goat [provided by RefSeq] Theoretical MW (kDa): 38.2 References: 1. Human orthologs of yeast vacuolar protein sorting Reactivity: Human proteins Vps26, 29, and 35: assembly into multimeric Applications: ELISA, WB-Ti, WB-Tr complexes. Haft CR, de la Luz Sierra M, Bafford R, (See our web site product page for detailed applications Lesniak MA, Barr VA, Taylor SI. Mol Biol Cell. 2000 information) Dec;11(12):4105-16. Protocols: See our web site at http://www.abnova.com/support/protocols.asp or product page for detailed protocols Specificity: This antibody is expected tp recognize isoform 1 (NP_004887.2) only. Form: Liquid Purification: Antigen affinity purification Concentration: 0.5 mg/mL Recommend Usage: ELISA (1:4000) Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user. Storage Buffer: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide) Storage Instruction: Store at -20°C. Aliquot to avoid repeated freezing and thawing. Entrez GeneID: 9559 Gene Symbol: VPS26A Page 1/1 Powered by TCPDF (www.tcpdf.org).