The Editor of The Journal of Pharmacology and Experimental Therapeutics wishes to express appreciation to the following colleagues who acted at Guest Editors for Specific Fields in 1994. Martin W. Adler Allan M. Lefer Edson X. Albuquerque Roberto Levi Vernon S. Bishop Benedict R. Lucchesi Theodore J. Cicero Irwin LucId Marlene L. Cohen David R. Manning Alan Frazer William H. Morse Robert Freedman Garth Powis Eitan Friedman Roger D. Spealman Ray W. Fuller Milt Teitler Richard Gillis Mary Vore Elizabeth H. Jeffery Michael Williams Additionally, sincere thanks are due to 1039 of our colleagues not on the Editorial Advisory Board who reviewed articles for the Journal in 1994. Their contributions are acknowledged individually in the Annual Report of The Journal to The Board of Publications Trustees of The American Society for Pharmacology and Experimental Therapeutics. INDEX Volume 273, April-June, 1995 A-85653, repeated daily, effects on rota- tor binding and in vivo activities beta-i, effects in SNS-evoked adrenal tion and striatal c-fos expression, for anandamide analogs, 1172 catecholamine release, in anes- 1483 Adams, J. L., see Chabot-Fletcher, M. C., thetized dogs, 1337 Abecarnil, modulation of basal and stress- 1147 Advenier, C., see F#{233}l#{233}tou,M., 1071 induced release of acetyicholine Adams, J. U., see Liu-Chen, L.-Y., 1047 Afferent nerves, capsaicin-sensitive, regu- and dopamine in rat brain by, 241 Adams, M., see Cicero, T. J., 386 lation of jejunal arterioles by, in Absence seizures, GHB-induced, endoge- Adenosine, metabolism of exogenous cyclic N. brasiliensis-sensitized rats, nous GABA in, in rat, 1534 AMP to, in rat kidney, 728 337 [3HIABT-418, receptor binding character- Adenosine analogues, TNF-a inhibition v-Agatoxin-IVA, blockade of voltage- istics, in rat brain, 1434 by, 1506 sensitive calcium channels by, at Abuse, see Alcohol abuse; Drug abuse Adenosine receptors mouse neuromuscular junction, Acetaminophen, cytotoxicity in human A1 248 CYP2E1-transfected HepG2 cells, interaction with caffeine, effects on Ahmed, M. S., see Cemerikic, B., 987 1497 hippocampal acetyicholine re- Ahmmed, G. U., see Yoshida, A., 702 Acetylcholine lease, 637 Akai, T., Ozawa, M., Yamaguchi, M., basal and stress-induced release, modu- potassium current activated by, char- Mizuta, E. and Kuno, S.: Combi- lation by abecarnil and imidaze- acterization of, in rat locus cer- nation treatment of the partial nil, in rat brain, 241 uleus neurons, 537 D2 agonist terguride with the D1 hippocampal release, caffeine effects on, agonist modulation of intraocular pres- agonist SKF 82958 in 1-methyl- 4-phenyl-i,2,3,6-tetrahydropyri- 637 sure by, in rabbits, 320 interaction with K channel blockers, Adenylate cyclase dine-lesioned parkinsonian cyno- molgus monkeys, 309 effects on atrial repolarization, beta adrenergic response of, in rat brain, Akima, M., see Takanashi, H., 624 1095 415 Albumin, serum, role in nitric oxide dose- Na influx and catecholamine secretion bradykinin inhibition of, colon contrac- response, in isolated perfused rat evoked by, reduction by ginseng tion evoked by, 344 kidney, 855 saponins, in bovine adrenal chro- Adhesion molecules, role in cardiovascular Albuquerque, E. X., see Ishihara, K., 1459, maffin cells, 629 pharmacology, meeting review, 1471 signal transduction pathways in gall- 569 Albuterol, salmeterol blockade of inhibi- bladder muscle, 650 Adler, M. W., see Belkowski, S. M., 1491 tion of eosinophil secretion by, Acetylcholine receptors Adrenal chromaffin cells, ACh-evoked 850 muscarinic Na influx and catecholamine se- Alcohol abuse, promotion by low brain do- bladder subtypes, 959 cretion in, reduction by ginseng pamine, 373 gallbladder muscle subtypes, 650 saponins, in bovine, 629 Alfentanil, antinociceptive effects in tail- interaction with K channel blockers, Adrenal gland, catecholamine release in, withdrawal procedure, buprenor- effects on atrial repolarization, SNS-evoked, effects of beta adre- phine antagonism of, in rhesus noceptors in, in anesthetized 1095 monkey, 1345 regulation of cardiac CFTR Cl cur- dogs, 1337 Alicea, C., see Belkowski, S. M., 1491 Adrenergic nerves, ear artery, facilitatory rent by, effects of quaternary am- Alkondon, M., see Ishihara, K., 1459, 1471 prejunctional purinoceptors on, monium compounds on, 470 Allavena, A., see Martelli, A., 113 role in cicletanine effects on kidney in rabbit, 1390 Allergy function, 1197 Adrenergic neurons, modulation by SB 202235 asthmatic effects in, in mod- nicotinic 5-HT1A receptors, in rat, 1032 els, 1147 ABT-418 binding characteristics, in Adrenergic receptors trimellitic anhydride, role of comple- rat brain, 1434 alpha-2 ment system in, in lung, 793 hippocampal, lead effects on, in rat, medullary, effects in conscious spon- Ailing, K., see Pell#{243}n, R., 138 1471 taneously hypertensive rats, 1162 Alloantigen, specific CTL activity, effects Acid secretion, in gastric glands, effects of modulation of spinal sympathetic re- of exogenous corticosterone on, in PDE IV inhibitors on, in rabbit, flex by, in rat, 380 mice, 823 1396 13H]RX 821002 vs [3H]rauwolscine Allografts, heart, gramicidin prolongation Action potential, dimethyl sulfoxide ef- binding, in nine tissues and cell of survival, in rat, 223 fects on, in guinea pig ventricular lines, 1287 Aloyo, V. J., Ruffin, J. S., Pazdalski, P. 5., preparations, 1273 alpha-i, agonist preconditioning, in rat Kirifides, A. L. and Harvey, J. A.: Action potential duration, effects of inter- hearts, 689 [3H]WIN 35,428 binding in the action between K channel block- beta caudate nucleus of the rabbit: Ev- ers and acetylcholine on, 1095 brain signaling, in rat, 415 idence for a single site on the do- Activated protein C, antiinflammatory ef- effects in SNS-evoked adrenal cate- pamine transporter, 435 fects, in rat models, 193 cholamine release, in anesthe- Alper, S. L., see Brugnara, C., 266 Activity stress gastric lesions, dopamine tized dogs, 1337 Amantadine, renal transport, site-selec- Dl and D2 receptor effects in, in beta-2 tive effect of bicarbonate on, 72 rats, 1001 effects in SNS-evoked adrenal cate- Ambler, S. J., see Chrandasekhar, S., 1519 Adams, I. B. , Ryan, W., Singer, M., cholamine release, in anesthe- y-Aminobutyric acid Thomas, B. F., Compton, D. R., tized dogs, 1337 ethanol interaction, prediction by zolpi- Razdan, R. K. and Martin, B. R.: salmeterol blockade of eosinophil in- dem effects on GABA-induced in- Evaluation of cannabinoid recep- hibition by, 850 hibition, in rat brain regions, 526 1562 Index Vol. 273 in GHB-induced absence seizures, in Anorectic agents, effects on deprivation- sympathetic vasoconstriction of, modu- rat, 1534 induced feeding and taste aver- lation by sensory nerves and NO 5-HT interactions in substantia nigra, sion conditioning, in rats, 1203 in, in rat iris, 918 modulation of MDMA-induced Antiarrhythmics Ashkenazi, I. E., see Gozes, I., 161 striatal dopamine release by, class-I-type, sodium channel blockade Asin, K. E., Bednarz, L., Nikkel, A. and 1063 by, postischemia, 1403 Perner, R.: Rotation and striatal presynaptic GHB and GABAB receptor- electrophysiologic effects c-fos expression after repeated, mediated release of, in rat tha- effects of infarct healing on, 315 daily treatment with selective do- lamic ventrobasal nucleus, 1534 in guinea pig cardiac isolated prepa- pamine receptor agonists and -y-Aminobutyric acidB, presynaptic inhibi- rations, 1264 levodopa, 1483 tion by adenosine, in midbrain inhibition of G-protein and K channels Asthma, allergic, SB 202235 effects in, in dopamine neurons, 576 by, in thyroid cells, 702 models, 1147 2-Amino-N-(1,2-diphenylethyl)acetamide Antibiotics, (3-lactam, intestinal transport, Atenolol, effects in SNS-evoked adrenal hydrochloride, anticonvulsant ef- in rat, rabbit and human small catecholamine release, in anes- ficacy/safety properties of, 1023 intestines, 26 thetized dogs, 1337 p-Aminohippurate, renal transport, in Antigen, 6-THC modulation of macro- ATRA, see Retinoic acid rabbit renal basolateral mem- phage processing of, 1216 Atrial natriuretic peptide, endothelin ef- brane vesicles, 146 Antimalarials, amodiaquine metabolism fects dependent on, modulation by inhibitors Aminopyrine, secretion in gastric glands, and activity, effects of chemical of neutral endopep- effects of PDE N inhibitors on, in substitution on, in mouse, 393 tidase and cGMP-PDE, 744 rabbit, 1396 Antinociception Atrial repolarization, effects of interaction Ammonium, quaternary compounds, mus- anandamide, in mice, 1235 between K channel blockers and carinic regulation of cardiac 9-THC, anandamide blockade of, in acetylcholine on, 1095 Audinot, V., see Gobert, A., 1032; Milan, CFTR Cl current by, 470 mice, 1235 M. J., 1418; Schreiber, R., 101 Amodiaquine, metabolism and activity, ef- dynorphin A-(2-17) naloxone-insensi- Auta, J., see Thompson, D. M., 1307 fects of chemical substitution on, tive, in writhing assay, 802 Autoradiography, localization and charac- in mouse, 393 fluoroanandamide, in mice, 1235 terization of[3H]a-trinositol bind- Amphetamine, dose-related effects on zif/ intrathecal clonidine, mediation by spi- ing sites, in human and mamma- 268 and preprodynorphin mRNA nal nonadrenergic imidazoline re- ceptors, in rat, 1057 han tissues, 461 expression, in rat forebrain, 909 morphine, tolerance to, prevention with Autoreceptors Analgesia, see also Antinociception irreversible opioid antagonists, muscannic, m2 subtype identification, morphine, sensitivity to, adverse effects 680 in rat striatum, 273 of paternal opiates exposure