CURRICULUM VITAE Revised June 2020 NAME: Ilo Elmar Leppik CITIZENSHIP: USA ADDRESS: Work: College of Pharmacy University of Minnesota Room 461 717 Delaware St SE Minneapolis, MN 55414 KEY ACADEMIC APPOINTMENTS: University of Minnesota - Minneapolis, Minnesota - Professor, College of Pharmacy, 2004 - present - Adjunct Professor of Neurology, November 1989 - Present - Professor of Neurology, July 1987 - 1989 - Adjunct Professor of Pharmacy Practice, November 1987 - 2004 - Associate Professor of Neurology, July 1980 - July, 1987 - Clinical Associate Professor of Pharmacy, 1986 - 1987 - Assistant Professor of Neurology, July 1976 - June 1980 KEY OFFICES HELD IN NATIONAL ORGANIZATIONS: President, American Epilepsy Society, Dec 1993 - Dec 1994 President, Central Society for Neurological Research, 1991 - 1992 Board of Directors, American Board of Clinical Neurophysiology, 1991 - 1994 Vice President, American Epilepsy Society, 1991 - 1993 Chairman, Guidelines Committee American Epilepsy Society 1994-1999 Chairman, Rules Committee, American Epilepsy Society, 1980 - 1982 Treasurer, American Epilepsy Society, 1983 - 1986 Secretary, Professional Advisory Board, Epilepsy Foundation of America, 1983 - 1987 Board member, Epilepsy Foundation of America, 1982 - 1992 Executive Committee, American Epilepsy Society, 1983 - 86 Chairman-Elect, Professional Advisory Board, Epilepsy Foundation of America, 1987 - 1989 Chairman, Professional Advisory Board, Epilepsy Foundation of America, 1989 - 1991 SPECIAL APPOINTMENTS Panelist, NIH Consensus Conference on Electroshock Therapy, Bethesda, MD, June, 1985 American Member, WHO Seminar on Epilepsy, Beijing, China, 1984 Member, NIH Program Project B Review Committee, 1991 - 1992 Member, Program Project A Review Committee, 1992 – 1994 Ad Hoc Reviewer NIH Review Committees 1998- 2007 Revised: 09/29/20 BOARD CERTIFICATION: National Medical Board, 1968 American Board of Psychiatry and Neurology, 1977 American Board of Qualification in EEG, 1978 MAJOR HONORS, AWARDS AND ELECTIONS: The Penfield Award for Excellence, Montreal Neurological Institute 1975 Elected to Central Society for Neurological Research, 1982 International League Against Epilepsy Clinical Pharmacology Award, 1986 Named in Epilepsy Section of The Best Doctors in America, 1992 to present Hans Berger Award, 1995 Named in Who's Who in Science and Engineering, 1996 to present Named in Who's Who in the World, 1997 to present Elected Honorary Fellow, Hong Kong Epilepsy Society, 2003 Elected Honorary Fellow, Estonian Neurological Society, 2007 William Lennox Award for Lifetime Achievement, American Epilepsy Society 2007 Ludvig Puusepp Achievement Award, Estonian Neurological Society 2007 EDITORSHIPS, EDITORIAL BOARDS & REVIEWS: Founding and Managing Editor, Epilepsy Research, 1986 - 2006 International Editorial Board, Disease Management & Health Outcomes, 1997 - 2000 Editorial Advisory Board, Neurology Reviews, 1994 - present Editor, Merritt-Putnam Quarterly, 1985 - 1987 Editorial Board, Epilepsia, 1980 - 1986 Editorial Board, Therapeutic Drug Monitoring, 1987 - 1990 Editor, Profiles in Seizure Management, 2003-2005 Editorial Advisory Board, CNS Long-Term Care, 2004-present Reviewer of Papers and Books for: - Neurology - Annals of Neurology - Archives of Neurology - Epilepsia - Synapse - Therapeutic Drug Monitoring - Post-Graduate Medicine - American Medical Association Drug Evaluations - Mayo Clinic Journal EDUCATION: Ames High School, Ames, Iowa (1960) B.Sc., Chemistry (1964), Haverford College - Philadelphia, Pennsylvania M.D. (1968), University of Pennsylvania - Philadelphia, Pennsylvania 2 INTERNSHIP, RESIDENCY AND FELLOWSHIPS: University of Wisconsin - Madison, Wisconsin - Straight Medical Intern (June 1968 - May 1969) - Neurology Resident (June 1969 - September 1970) Montreal Neurological Institute, McGill University - Montreal, Quebec, Canada - Senior Resident, C Service (November 1972 - December 1972) - Consulting Resident, Royal Victoria Hospital (January - June 1973) - Senior Resident, Pediatric Neurology, Montreal Children’s Hospital (June - December 1973) - EEG Fellow, Dr. P. Gloor, Supervisor (January - June 1974) - Medical Research Council of Canada, Research Fellow in Neuropharmacology - Dr. A. Sherwin, Supervisor (July 1974 - June 1976) TRAINING GRANTS University of Pennsylvania, Philadelphia, PA - Medical Student Research Training Program Grant - Surgery, Summer 1961 - Medical Student Research Training Program Grant - Cardiology, Summer 1962 - Medical Student Research Training Program Grant - Cardiology, Summer 1963 - Medical Research Council of Canada July 1974-1976 OFFICES HELD IN STATE ORGANIZATIONS: President, Association of Neurologists of Minnesota, 1984 – 1989 Alternate Delegate, House of Delegates, Minnesota Medical Society, 1983 Delegate, House of Delegates, Minnesota Medical Society, 1985 Vice Chairperson, Minnesota Driver’s License Review Panel, 1985 - 86 ADMINISTRATIVE RESPONSIBILITIES: Principal Investigator, NIH Program Project, 1991 to present Director of Research, MINCEP Epilepsy Care, 1989 to present Director, Epilepsy Clinical Research Program, College of Pharmacy, University of Minnesota, 1996 to present Member, Clinical Faculty Appointment and Promotion Subcommittee, Department of Neurology, University of Minnesota, 1992 to present Director, Epilepsy Research Center, Department of Neurology, 1986 to 1996 Associate Director, Comprehensive Epilepsy Program, 1980 to 1986 Chairman, Special Education Committee, Department of Neurology, 1976 to 1979 Chairman, Task Force on Review of Residency Training Program, 1984 Chairman, Futures Committee on Financial Affairs, Ramsey Clinic, 1981 Member, Fringe Benefits Committee, Ramsey Clinic, 1978 to 1986 Member, Research Committee, Ramsey Foundation, 1977 to 1986 Member, Human Resources Committee, Ramsey Clinic, 1984 to 1986 Member, Practice Committee, Ramsey Clinic, 1982 to 1984 Member, Oversight Committee, Ramsey Clinic, 1983 to 1985 Member, Resident Committee, Ramsey Clinic, 1981 to 1986 Member, Toxicology Committee, Ramsey Clinic, 1979 to 1986 Member, Task Force on Department of Neurology Planning and Strategy for Focus, 1987 3 OTHER: Patent : US Appl No. 13/547,866/HUL Ref. 80008-US-CNT3/WH Ref. 2205889.127US2. March 3, 2017 Photography Editor, University of Pennsylvania Medical School Yearbook (1968) President, Fellows Society, Montreal Neurological Institute (1974-75) NINCDS Site Visit Team - Member, NINCDS site visit team University of Washington, Seattle, Washington, October, 1980 - Member, NINCDS site visit team - UCLA, Los Angeles, November, 1980 - Member, NINCDS site visit team - Baylor University, Houston, 1982 - Member, NINCDS site visit team - UCLA, Los Angeles, March 1983 - Member, NINCDS site visit team - University of Washington, Seattle, August, 1983 - Member, NINCDS site visit team - University of Virginia, Richmond, July, 1986 and 1987 Examiner, American Board of Qualification in EEG: 1980 - New York, New York 1981 - New York, New York 1982 - Washington, D.C. 1983 - San Diego, California 1985 - Dallas, Texas 1986 - New Orleans, Louisiana 1992 - San Francisco, California Examiner, American Board of Psychiatry and Neurology, 1980. MEMBERSHIPS: American Academy of Neurology Fellow American Association for the Advancement of Science American Epilepsy Society American Medical Association Minnesota Medical Association Hennepin County Medical Society Canadian Neurological Society Central Society for Neurological Research American EEG Society Voyageurs Chapter, Neurosciences Society MILITARY SERVICE: Neurologist - Andrews Air Force Base, Washington, D.C. (October 1970 - October 1972) Chief of Neurology (June 1972-Oct 1972) 4 PUBLICATIONS 1. Journal Articles 2. Books 3. Book Chapters 4. Published Abstracts 5 JOURNAL ARTICLES (chronological order) 1. Pierce WS, Morris L, Gardiner BN, Leppik, IE et al. Experimental use of single mechanical ventricle to replace the dog’s heart. Trans Amer Soc Artif Int Organs 1965;11:271-276. 2. Messert B, Leppik IE, Sato S. Diplopia and involuntary eye closure in spontaneous cerebellar hemorrhage. Stroke 1976;7:305-307. 3. Sherwin AL, Harvey CD, Leppik IE, et al. Correlation between red cell and free plasma phenytoin levels in renal disease. Neurology 1976;26:874-878. 4. Leppik IE, Sherwin AL. Anticonvulsant activity of phenobarbital and phenytoin in combination. J Pharmacol Exp Ther 1977;200:570-576. 5. Leppik IE, Thompson CJ, Ethier R, et al. Diatrizoate in computer cranial tomography: a quantitative study. Invest Radio 1977;12:21-26. 6. McAuliffe JJ, Sherwin AL, Leppik IE, et al. Salivary levels of anticonvulsants: a practical approach to drug monitoring. Neurology 1977;27:409-413. 7. Cranford RE, Leppik IE, Patrick B, Anderson CB, Kostick B. Intravenous phenytoin: clinical and pharmacokinetic aspects. Neurology 1978;28:874-880. 8. Matthews SJ, Pepin SM, Leppik IE. Clonazepam in the treatment of epilepsy. Minnesota Medicine 1978;61:439-442. 9. Nino HE, Leppik IE, Lai C, et al. Progressive sensory loss one year after bullet injury of spinal cord. JAMA 1978;240:1173-1174. 10. Cranford RE, Leppik IE, Patrick B, Anderson CB, Kostick B. Intravenous phenytoin in acute treatment of seizures. Neurology 1979;29:1474-1479. 11. Leppik IE, Cloyd JD, Sawchuk RJ, Pepin SM. Compliance and variability of plasma phenytoin levels in epileptic patients. Ther Drug Mon 1979;1:475-483. 12. Leppik IE, Ramani V, Sawchuk RJ, Gumnit RJ. Increased clearance of phenytoin during infectious mononucleosis. New Eng J Med 1979;300:481-482. 13. Leppik IE, Sherwin