Estonian Statistics on Medicines 2016 ATC code ATC group / Active substance (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/ day A ALIMENTARY TRACT AND METABOLISM 167,8985 A01 STOMATOLOGICAL PREPARATIONS 0,0738 A01A STOMATOLOGICAL PREPARATIONS 0,0738 A01AB Antiinfectives and antiseptics for local oral treatment 0,0738 A01AB09 Miconazole (O) 7088 g 0,2 g 0,0738 A01AB12 Hexetidine (O) 1951200 ml A01AB81 Neomycin+ Benzocaine (dental) 30200 pieces A01AB82 Demeclocycline+ Triamcinolone (dental) 680 g A01AC Corticosteroids for local oral treatment A01AC81 Dexamethasone+ Thymol (dental) 3094 ml A01AD Other agents for local oral treatment A01AD80 Lidocaine+ Cetylpyridinium chloride (gingival) 227150 g A01AD81 Lidocaine+ Cetrimide (O) 30900 g A01AD82 Choline salicylate (O) 864720 pieces A01AD83 Lidocaine+ Chamomille extract (O) 370080 g A01AD90 Lidocaine+ Paraformaldehyde (dental) 405 g A02 DRUGS FOR ACID RELATED DISORDERS 47,1312 A02A ANTACIDS 1,0133 Combinations and complexes of aluminium, calcium and A02AD 1,0133 magnesium compounds A02AD81 Aluminium hydroxide+ Magnesium hydroxide (O) 811120 pieces 10 pieces 0,1689 A02AD81 Aluminium hydroxide+ Magnesium hydroxide (O) 3101974 ml 50 ml 0,1292 A02AD83 Calcium carbonate+ Magnesium carbonate (O) 3434232 pieces 10 pieces 0,7152 DRUGS FOR PEPTIC ULCER AND GASTRO- A02B 46,1179 OESOPHAGEAL REFLUX DISEASE (GORD) A02BA H2-receptor antagonists 2,3855 A02BA02 Ranitidine (O) 340327,5 g 0,3 g 2,3624 A02BA02 Ranitidine (P) 3318,25 g 0,3 g 0,0230 A02BC Proton pump inhibitors 43,7324 A02BC01 Omeprazole (O) 263238,18 g 0,02 g 27,4097 A02BC02 Pantoprazole (O) 172288,06 g 0,04 g 8,9697 A02BC02 Pantoprazole (P) 356,4 g 0,04 g 0,0186 A02BC03 Lansoprazole (O) 9,87 g 0,03 g 0,0007 A02BC05 Esomeprazole (O) 102877,88 g 0,03 g 7,1414 A02BC05 Esomeprazole (P) 2770 g 0,03 g 0,1923 A02BD Combinations for eradication of Helicobacter pylori <0,0001 A02BD08 Bismuth subcitrate+ Tetracycline+ Metronidazole (O) 240 pieces 12 pieces <0,0001 DRUGS FOR FUNCTIONAL GASTROINTESTINAL A03 7,9186 DISORDERS DRUGS FOR FUNCTIONAL GASTROINTESTINAL A03A 6,9014 DISORDERS A03AA Synthetic anticholinergics, esters with tertiary amino group 0,9452 A03AA04 Mebeverine (O) 136170 g 0,3 g 0,9452 A03AB Synthetic anticholinergics, quaternary ammonium compounds <0,0001 A03AB02 Glycopyrronium bromide (P) 0,02 g 3 mg <0,0001 A03AD Papaverine and derivatives 4,4043 A03AD01 Papaverine hydrochloride (P) 65,8 g 0,1 g 0,0014 A03AD02 Drotaverine (O) 206916,32 g 0,1 g 4,3090 A03AD02 Drotaverine (P) 4507 g 0,1 g 0,0939 A03AX Other drugs for functional gastrointestinal disorders 1,5519 A03AX13 Simeticone (O) 372600,6965 g 0,5 g 1,5519 A03B BELLADONNA AND DERIVATIVES, PLAIN 0,1142 A03BA Belladonna alkaloids, tertiary amines 0,0971 A03BA01 Atropine (O, P) 25,39 g 0,0015 g 0,0352 A03BA01 Atropine (P) 44,53 g 0,0015 g 0,0618 1/41 Estonian Statistics on Medicines 2016 ATC code ATC group / Active substance (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/ day Belladonna alkaloids, semisynthetic, quaternary ammonium A03BB 0,0171 compounds A03BB01 Butylscopolamine (O) 58,4 g 0,06 g 0,0020 A03BB01 Butylscopolamine (P) 430,5 g 0,06 g 0,0149 A03BB01 Butylscopolamine (R) 4,8 g 0,06 g 0,0002 A03F PROPULSIVES 0,9030 A03FA Propulsives 0,9030 A03FA01 Metoclopramide (O) 10519 g 0,03 g 0,7302 A03FA01 Metoclopramide (P) 1899,3 g 0,03 g 0,1318 A03FA01 Metoclopramide (R) 0,5 g 0,03 g <0,0001 A03FA03 Domperidone (O) 589,8 g 0,03 g 0,0409 A04 ANTIEMETICS AND ANTINAUSEANTS 0,1264 A04A ANTIEMETICS AND ANTINAUSEANTS 0,1264 A04AA Serotonin (5-HT3) antagonists 0,1117 A04AA01 Ondansetron (P) 29,62 g 0,016 g 0,0039 A04AA02 Granisetron (O) 60,64 g 0,002 g 0,0631 A04AA02 Granisetron (P) 64,4 g 0,003 g 0,0447 A04AD Other antiemetics 0,0147 A04AD01 Scopolamine (TD) 15 pieces 1 pieces <0,0001 A04AD12 Aprepitant (O) 395,865 g 0,095 g 0,0087 A04AD81 Fosaprepitant (P) 274,65 g 0,095 g 0,0060 A05 BILE AND LIVER THERAPY 2,4278 A05A BILE THERAPY 0,4881 A05AA Bile acid preparations 0,4881 A05AA02 Ursodeoxycholic acid (O) 175775 g 0,75 g 0,4881 A05B LIVER THERAPY, LIPOTROPICS 1,9397 A05BA Liver therapy 1,9397 A05BA03 Silymarin (O) 2963650 pieces A05BA80 Essential phospholipids (O) 2794350 pieces 3 pieces 1,9397 A05BA80 Essential phospholipids (P) 1865 pieces A06 DRUGS FOR CONSTIPATION 15,1259 A06A DRUGS FOR CONSTIPATION 15,1259 A06AB Contact laxatives 7,1290 A06AB02 Bisacodyl (O) 14645 g 0,01 g 3,0498 A06AB02 Bisacodyl (R) 875,6 g 0,01 g 0,1823 A06AB06 Senna glycosides (O) 10300 pieces 1 pieces 0,0214 A06AB08 Sodium picosulfate (O) 9304,062 g 0,005 g 3,8751 A06AB80 Sodium picosulfate+ Magnesium oxide+ Citric acid (O) 186 pieces 2 pieces 0,0002 A06AD Osmotically acting laxatives 7,1545 A06AD11 Lactulose (O) 21946884,8 g 6,7 g 6,8216 A06AD15 Macrogol (O) 1598600 g 10 g 0,3329 Macrogol+ Sodium citrate+ Citric acid+ Sodium chloride+ A06AD80 35000 ml Potassium chloride (O) Sodium sulphate, anhydrous+ Potassium chloride+ Sodium A06AD81 53092 pieces chloride+ Macrogol+ Sodium hydrogen carbonate (O) Macrogol+ Sodium sulphate, anhydrous+ Sodium chloride+ A06AD83 1 pieces Potassium chloride+ Ascorbic acid+ Sodium ascorbate (O) Sodium sulphate, anhydrous+ magnesium sulfate A06AD85 1102112 ml heptahydrate+ Potassium sulphate (O) A06AG Enemas 0,8425 A06AG11 Laurilsulfate, incl. combinations+ Sorbitol+ Sodium citrate (R) 404564 pieces 1 pieces 0,8425 A06AH Peripheral opioid receptor antagonists A06AH03 Naloxegol (O) 8,25 g A06AX Other drugs for constipation A06AX01 Glycerol (R) 300 pieces 2/41 Estonian Statistics on Medicines 2016 ATC code ATC group / Active substance (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/ day Sodium hydrogen carbonate+ Sodium dihydrogen phosphate A06AX80 100 pieces (R) ANTIDIARRHEALS, INTESTINAL A07 3,8855 ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS A07A INTESTINAL ANTIINFECTIVES <0,0001 A07AA Antibiotics <0,0001 A07AA11 Rifaximin (O) 7,2 g 0,6 g <0,0001 A07B INTESTINAL ADSORBENTS 0,4636 A07BC Other intestinal adsorbents 0,4636 A07BC05 Diosmectidum (O) 2003400 g 9 g 0,4636 A07C ELECTROLYTES WITH CARBOHYDRATES A07CA Oral rehydration salt formulations Sodium chloride+ Potassium chloride+ Sodium citrate+ A07CA80 60780 pieces Glucose (O) A07D ANTIPROPULSIVES 0,9245 A07DA Antipropulsives 0,9245 A07DA03 Loperamide (O) 4439,5 g 0,01 g 0,9245 A07E INTESTINAL ANTIINFLAMMATORY AGENTS 1,9117 A07EA Corticosteroids acting locally 0,0003 A07EA06 Budesonide (O) 1,2 g 0,009 g 0,0003 A07EA06 Budesonide (R) 1,6177 g A07EC Aminosalicylic acid and similar agents 1,9114 A07EC01 Sulfasalazine (O) 783050 g 2 g 0,8154 A07EC02 Mesalazine (O) 722900 g 1,5 g 1,0036 A07EC02 Mesalazine (R) 66584 g 1,5 g 0,0924 A07F ANTIDIARRHEAL MICROORGANISMS 0,5857 A07FA Antidiarrheal microorganisms 0,5857 A07FA02 Saccharomyces boulardii (O) 281237,5 g 1 g 0,5857 A07X OTHER ANTIDIARRHEALS A07XA Other antidiarrheals A07XA04 Racecadotril (O) 2681,92 g A08 ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS 0,0171 A08A ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS 0,0171 A08AB Peripherally acting antiobesity products 0,0171 A08AB01 Orlistat (O) 2958,48 g 0,36 g 0,0171 A09 DIGESTIVES, INCL. ENZYMES 1,4609 A09A DIGESTIVES, INCL. ENZYMES 1,4609 A09AA Enzyme preparations 1,4603 A09AA02 Lipase+ Amylase+ Protease (O) 2804925 pieces 4 pieces 1,4603 A09AC Enzyme and acid preparations, combinations 0,0006 A09AC80 Pepsin+ Betaine (O) 800 pieces 3 pieces 0,0006 A10 DRUGS USED IN DIABETES 61,5309 A10A INSULINS AND ANALOGUES 16,5197 A10AB Insulins and analogues for injection, fast-acting 6,2793 A10AB01 Insulin (human) (P) 900000 U 40 U 0,0469 A10AB04 Insulin lispro (P) 24964500 U 40 U 1,2997 A10AB05 Insulin aspart (P) 81061500 U 40 U 4,2203 A10AB06 Insulin glulisine (P) 13684500 U 40 U 0,7124 A10AC Insulins and analogues for injection, intermediate-acting 0,1243 A10AC01 Insulin (human) (P) 2388000 U 40 U 0,1243 Insulins and analogues for injection, intermediate- or long- A10AD 1,4836 acting combined with fast-acting A10AD04 Insulin lispro (P) 10512000 U 40 U 0,5473 A10AD05 Insulin aspart (P) 17985000 U 40 U 0,9363 A10AE Insulins and analogues for injection, long-acting 8,6325 A10AE04 Insulin glargine (P) 94092000 U 40 U 4,8987 3/41 Estonian Statistics on Medicines 2016 ATC code ATC group / Active substance (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/ day A10AE05 Insulin detemir (P) 71718000 U 40 U 3,7338 A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS 45,0111 A10BA Biguanides 19,7828 A10BA02 Metformin (O) 18999126 g 2 g 19,7828 A10BB Sulfonylureas 15,4082 A10BB07 Glipizide (O) 1414,95 g 0,01 g 0,2947 A10BB09 Gliclazide (O) 248991 g 0,06 g 8,6421 A10BB12 Glimepiride (O) 6215,1 g 0,002 g 6,4715 A10BD Combinations of oral blood glucose lowering drugs 4,2250 A10BD07 Metformin+ Sitagliptin (O) 1863400 pieces 2 pieces 1,9403 A10BD08 Metformin+ Vildagliptin (O) 803160 pieces 2 pieces 0,8363 A10BD10 Metformin+ Saxagliptin (O) 308580 pieces 2 pieces 0,3213 A10BD11 Metformin+ Linagliptin (O) 659940 pieces 2 pieces 0,6872 A10BD15 Metformin+ Dapagliflozin (O) 150528 pieces 2 pieces 0,1567 A10BD20 Metformin+ Empagliflozin (O) 272040 pieces 2 pieces 0,2833 A10BF Alpha glucosidase inhibitors 0,0001 A10BF01 Acarbose (O) 21 g 0,3 g 0,0001 A10BG Thiazolidinediones 0,0883 A10BG03 Pioglitazone (O) 1271,34 g 0,03 g 0,0883 A10BH Dipeptyl peptidase 4 (DPP-4) inhibitors 3,2135 A10BH01 Sitagliptin (O) 72375,1 g 0,1 g 1,5072 A10BH02 Vildagliptin (O) 7788 g 0,1 g 0,1622 A10BH03 Saxagliptin (O) 522,9 g 5 mg 0,2178 A10BH04 Alogliptin (O) 32,2 g 25 mg 0,0027 A10BH05 Linagliptin (O) 3178,05 g 5 mg 1,3237 A10BX Other blood glucose lowering drugs, excl.