PDF Output of CLIC (Clustering by Inferred Co-Expression)

PDF Output of CLIC (Clustering by Inferred Co-Expression)

PDF Output of CLIC (clustering by inferred co-expression) Dataset: Num of genes in input gene set: 21 Total number of genes: 16493 CLIC PDF output has three sections: 1) Overview of Co-Expression Modules (CEMs) Heatmap shows pairwise correlations between all genes in the input query gene set. Red lines shows the partition of input genes into CEMs, ordered by CEM strength. Each row shows one gene, and the brightness of squares indicates its correlations with other genes. Gene symbols are shown at left side and on the top of the heatmap. 2) Details of each CEM and its expansion CEM+ Top panel shows the posterior selection probability (dataset weights) for top GEO series datasets. Bottom panel shows the CEM genes (blue rows) as well as expanded CEM+ genes (green rows). Each column is one GEO series dataset, sorted by their posterior probability of being selected. The brightness of squares indicates the gene's correlations with CEM genes in the corresponding dataset. CEM+ includes genes that co-express with CEM genes in high-weight datasets, measured by LLR score. 3) Details of each GEO series dataset and its expression profile: Top panel shows the detailed information (e.g. title, summary) for the GEO series dataset. Bottom panel shows the background distribution and the expression profile for CEM genes in this dataset. Overview of Co-Expression Modules (CEMs) with Dataset Weighting Scale of average Pearson correlations Num of Genes in Query Geneset: 21. Num of CEMs: 1. 0.0 0.2 0.4 0.6 0.8 1.0 Mrpl40 Mrpl18 Mrps22 Mrpl11 Mrpl28 Mrpl13 Mrpl34 Mrps12 Mrpl47 Mrpl20 Mrpl39 Mrpl43 Mrpl37 Mrpl48 Mrpl49 Mrpl32 Dap3 Mrpl9 Mrpl51 Mrpl35 Mrps14 Mrpl40 Mrpl18 Mrps22 Mrpl11 Mrpl28 Mrpl13 Mrpl34 Mrps12 Mrpl47 CEM 1 (448 datasets) Mrpl20 Mrpl39 Mrpl43 Mrpl37 Mrpl48 Mrpl49 Mrpl32 Dap3 Mrpl9 Mrpl51 Mrpl35 Singletons Mrps14 Symbol Num ofCEMGenes:18.Predicted774.SelectedDatasets:448.Strength:31.7 CEM 1,Geneset"[G]mitochondrialribosome",Page1 Timm17a Mrps18a Timm8b Timm13 Chchd1 Ccdc58 Mrps16 Mrps17 Mrps10 Mrps35 Mrps28 Mrps12 Mrps22 Sssca1 Ndufv2 Atp5g1 Stoml2 Psmb3 Psmg1 Mrpl36 Mrpl16 Mrpl55 Mrpl42 Mrpl22 Mrpl46 Mrpl12 Mrpl32 Mrpl49 Mrpl48 Mrpl37 Mrpl43 Mrpl39 Mrpl20 Mrpl47 Mrpl34 Mrpl13 Mrpl28 Mrpl11 Mrpl18 Mrpl40 Grpel1 Dpy30 Naa10 Mrps7 Polr2j Mrpl2 Mrpl9 Dap3 Slirp Clpp 0.0 1.0 GSE16874 [12] GSE8044 [6] GSE38031 [8] Only showingfirst200datasets-Seetxtoutputforfulldetails. GSE14004 [9] GSE18907 [12] GSE48397 [10] GSE21944 [6] GSE23833 [12] GSE20954 [14] GSE51080 [18] GSE13302 [30] GSE46496 [9] GSE56135 [8] GSE46606 [30] GSE41942 [6] GSE30160 [6] GSE11973 [6] GSE19885 [9] GSE15729 [15] GSE13611 [8] GSE31313 [22] GSE12498 [12] GSE45619 [6] GSE8555 [8] GSE22824 [24] GSE52474 [154] GSE31004 [8] GSE13693 [9] GSE46723 [6] GSE31940 [8] GSE26616 [6] GSE11333 [6] GSE10989 [6] GSE37191 [12] GSE47872 [6] GSE10273 [9] GSE20391 [11] GSE12518 [6] GSE55607 [18] GSE38754 [40] GSE13044 [59] GSE52542 [9] GSE46094 [10] GSE27114 [6] GSE55356 [6] GSE13432 [12] GSE48884 [12] GSE28389 [20] GSE15155 [12] GSE28417 [12] GSE51608 [6] GSE44923 [16] GSE59437 [30] GSE6998 [32] GSE27379 [6] GSE6674 [15] GSE13547 [12] GSE48811 [20] GSE21063 [24] GSE35226 [12] GSE41759 [14] GSE18587 [9] GSE20152 [8] GSE23009 [16] GSE46090 [12] GSE18135 [18] GSE5891 [6] GSE41907 [7] GSE32330 [12] GSE22180 [60] GSE33101 [8] GSE11220 [44] GSE10192 [24] GSE15624 [12] GSE15741 [6] GSE26096 [10] GSE9652 [11] GSE24291 [6] GSE8407 [17] GSE16454 [24] GSE31244 [6] GSE6875 [8] GSE38304 [8] GSE56755 [13] GSE7275 [8] GSE19338 [24] GSE17497 [10] GSE39449 [6] GSE13149 [25] GSE31028 [6] GSE34961 [9] GSE19954 [8] GSE17923 [6] GSE10210 [16] GSE7759 [112] GSE20523 [17] GSE27816 [14] GSE39233 [40] GSE40230 [15] GSE5035 [12] GSE51075 [12] GSE42299 [8] GSE23101 [20] GSE11110 [11] GSE11222 [42] GSE35396 [24] GSE15541 [12] GSE9975 [36] GSE23408 [39] GSE36665 [6] GSE27848 [16] GSE5332 [12] GSE37907 [24] GSE33471 [12] GSE33121 [10] GSE24061 [88] GSE22039 [9] GSE12430 [21] GSE26671 [12] GSE13421 [8] GSE4535 [6] GSE26299 [108] GSE18396 [6] GSE14308 [12] GSE20696 [8] GSE15267 [8] GSE31570 [6] GSE16994 [12] GSE14395 [24] GSE54207 [9] GSE40368 [10] GSE6030 [6] GSE3313 [24] GSE23923 [8] GSE56777 [8] GSE44260 [10] GSE47414 [18] GSE7948 [13] GSE32034 [14] GSE17373 [24] GSE13753 [10] GSE21549 [6] GSE24789 [9] GSE27811 [9] GSE57543 [6] GSE23040 [6] GSE25295 [25] GSE12049 [6] GSE53951 [10] GSE28559 [30] GSE24210 [16] GSE10912 [6] GSE53077 [8] GSE11291 [60] CEM+ CEM GSE11759 [6] GSE36392 [9] GSE32277 [33] GSE45744 [12] GSE7694 [12] GSE21041 [6] 0.0 GSE16679 [8] GSE7050 [18] GSE51385 [8] Scale ofaveragePearsoncorrelations GSE44118 [6] GSE21299 [12] GSE7784 [12] GSE6623 [12] GSE12432 [15] GSE12982 [53] 0.2 GSE51213 [16] GSE32199 [6] GSE15610 [12] GSE7707 [18] GSE35785 [10] GSE18500 [35] GSE22774 [6] GSE27092 [6] GSE31208 [8] 0.4 GSE21996 [14] GSE35091 [11] GSE59202 [8] GSE4718 [6] GSE4238 [24] GSE38837 [6] GSE24628 [16] GSE29241 [6] GSE11572 [12] 0.6 GSE43825 [31] GSE49248 [12] GSE19286 [6] GSE13227 [6] GSE46724 [6] GSE48790 [8] GSE23006 [48] GSE39820 [22] GSE8836 [56] 0.8 GSE35160 [6] GSE14406 [54] GSE33199 [64] GSE41095 [6] Score 349.71 352.53 357.44 357.92 358.57 359.80 361.86 365.23 367.43 367.63 369.18 373.11 375.18 375.69 379.69 380.04 380.93 386.40 389.20 389.81 392.80 394.36 395.18 399.13 403.51 405.21 416.82 434.19 434.56 441.10 454.39 457.26 1.0 Notes Gadd45gip1 Symbol Num ofCEMGenes:18.Predicted774.SelectedDatasets:448.Strength:31.7 CEM 1,Geneset"[G]mitochondrialribosome",Page2 Aurkaip1 Tomm22 Mrps18b Mrps18c Timm23 Timm10 Ndufaf2 Ndufaf6 Exosc4 Mrps34 Mrps23 Mrps26 Mrps33 H2-Ke2 Ndufb7 Ndufb5 Ndufb6 Uqcr11 Ndufa5 Ndufa8 Ndufs7 Dctpp1 Ndufs8 Psmb5 Psmb6 Mrpl41 Mrpl27 Gtf2h5 Atp5f1 C1qbp Polr2c Atp5j2 Hspe1 Znhit3 Naa38 Mrp63 Polr2f Yars2 Emg1 Sf3b5 Emc6 Nhp2 Sdhd Coq7 Phb2 Cyc1 Mtx1 Fxn Uxt 0.0 1.0 GSE16874 [12] GSE8044 [6] GSE38031 [8] Only showingfirst200datasets-Seetxtoutputforfulldetails. GSE14004 [9] GSE18907 [12] GSE48397 [10] GSE21944 [6] GSE23833 [12] GSE20954 [14] GSE51080 [18] GSE13302 [30] GSE46496 [9] GSE56135 [8] GSE46606 [30] GSE41942 [6] GSE30160 [6] GSE11973 [6] GSE19885 [9] GSE15729 [15] GSE13611 [8] GSE31313 [22] GSE12498 [12] GSE45619 [6] GSE8555 [8] GSE22824 [24] GSE52474 [154] GSE31004 [8] GSE13693 [9] GSE46723 [6] GSE31940 [8] GSE26616 [6] GSE11333 [6] GSE10989 [6] GSE37191 [12] GSE47872 [6] GSE10273 [9] GSE20391 [11] GSE12518 [6] GSE55607 [18] GSE38754 [40] GSE13044 [59] GSE52542 [9] GSE46094 [10] GSE27114 [6] GSE55356 [6] GSE13432 [12] GSE48884 [12] GSE28389 [20] GSE15155 [12] GSE28417 [12] GSE51608 [6] GSE44923 [16] GSE59437 [30] GSE6998 [32] GSE27379 [6] GSE6674 [15] GSE13547 [12] GSE48811 [20] GSE21063 [24] GSE35226 [12] GSE41759 [14] GSE18587 [9] GSE20152 [8] GSE23009 [16] GSE46090 [12] GSE18135 [18] GSE5891 [6] GSE41907 [7] GSE32330 [12] GSE22180 [60] GSE33101 [8] GSE11220 [44] GSE10192 [24] GSE15624 [12] GSE15741 [6] GSE26096 [10] GSE9652 [11] GSE24291 [6] GSE8407 [17] GSE16454 [24] GSE31244 [6] GSE6875 [8] GSE38304 [8] GSE56755 [13] GSE7275 [8] GSE19338 [24] GSE17497 [10] GSE39449 [6] GSE13149 [25] GSE31028 [6] GSE34961 [9] GSE19954 [8] GSE17923 [6] GSE10210 [16] GSE7759 [112] GSE20523 [17] GSE27816 [14] GSE39233 [40] GSE40230 [15] GSE5035 [12] GSE51075 [12] GSE42299 [8] GSE23101 [20] GSE11110 [11] GSE11222 [42] GSE35396 [24] GSE15541 [12] GSE9975 [36] GSE23408 [39] GSE36665 [6] GSE27848 [16] GSE5332 [12] GSE37907 [24] GSE33471 [12] GSE33121 [10] GSE24061 [88] GSE22039 [9] GSE12430 [21] GSE26671 [12] GSE13421 [8] GSE4535 [6] GSE26299 [108] GSE18396 [6] GSE14308 [12] GSE20696 [8] GSE15267 [8] GSE31570 [6] GSE16994 [12] GSE14395 [24] GSE54207 [9] GSE40368 [10] GSE6030 [6] GSE3313 [24] GSE23923 [8] GSE56777 [8] GSE44260 [10] GSE47414 [18] GSE7948 [13] GSE32034 [14] GSE17373 [24] GSE13753 [10] GSE21549 [6] GSE24789 [9] GSE27811 [9] GSE57543 [6] GSE23040 [6] GSE25295 [25] GSE12049 [6] GSE53951 [10] GSE28559 [30] GSE24210 [16] GSE10912 [6] GSE53077 [8] GSE11291 [60] CEM+ CEM GSE11759 [6] GSE36392 [9] GSE32277 [33] GSE45744 [12] GSE7694 [12] GSE21041 [6] 0.0 GSE16679 [8] GSE7050 [18] GSE51385 [8] Scale ofaveragePearsoncorrelations GSE44118 [6] GSE21299 [12] GSE7784 [12] GSE6623 [12] GSE12432 [15] GSE12982 [53] 0.2 GSE51213 [16] GSE32199 [6] GSE15610 [12] GSE7707 [18] GSE35785 [10] GSE18500 [35] GSE22774 [6] GSE27092 [6] GSE31208 [8] 0.4 GSE21996 [14] GSE35091 [11] GSE59202 [8] GSE4718 [6] GSE4238 [24] GSE38837 [6] GSE24628 [16] GSE29241 [6] GSE11572 [12] 0.6 GSE43825 [31] GSE49248 [12] GSE19286 [6] GSE13227 [6] GSE46724 [6] GSE48790 [8] GSE23006 [48] GSE39820 [22] GSE8836 [56] 0.8 GSE35160 [6] GSE14406 [54] GSE33199 [64] GSE41095 [6] Score 296.88 297.01 297.21 298.05 298.11 298.97 299.87 300.12 300.81 301.66 301.85 307.59 308.09 308.20 309.37 309.55 310.53 310.71 311.43 312.58 314.48 316.33 316.42 317.43 317.45 317.75 317.77 317.78 318.39 322.47 323.40 324.11 325.50 328.92 329.12 333.81 334.00 334.50 334.89 335.17 337.98 338.84 341.95 342.04 343.55 343.75 345.56 345.78 349.18 349.47 1.0 Notes Symbol Num ofCEMGenes:18.Predicted774.SelectedDatasets:448.Strength:31.7 CEM 1,Geneset"[G]mitochondrialribosome",Page3 BC003965 Rps19bp1 Samm50 Ndufb10 Dnajc15 Psmd12 Timm22 Uqcrfs1 Ndufaf5 N6amt2 Mrps30 Mrps31 Ndufb3 Aarsd1 Malsu1 Ndufa9 Ndufc1 Ndufs3 Pmpcb Psmg3 Psmb4 Psmc4 Mrpl50 Mrpl44 Mrpl45 Polr1d Cops3 Cops6 Nop10 Wdr18 Aimp2 Rpp30 Cops5 Uqcc2 Eif2b1 Atp5h Nudt1 Nudt2 Pfdn4 Banf1 Park7 Bola3 Phf5a Cisd1 Nme1 Lsm4 Glrx3 Pno1 Txn2 Adsl 0.0 1.0 GSE16874 [12] GSE8044 [6] GSE38031 [8] Only showingfirst200datasets-Seetxtoutputforfulldetails. GSE14004 [9] GSE18907 [12] GSE48397 [10] GSE21944 [6] GSE23833

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