Unti II- BP 505T. (Drug and cosmetic act 1940 and its rule 1945) Mr.Samir Patra Introduction: The drugs and cometics act 1940 and rules 1945 have been passed to regulate the import, manufacture, distribution and sale of drugs and cosmetics. All the operations related to drugs should be done by qualified persons. To have a check, on search operation the central and state government are established the state and central drug control authorities. Drug and cosmetics rule have been divided into 18 parts, each belong with a particular subject. There are two schedules to the act and 25 schedules to the rules. Schedule G It contains the list of the drugs should be used under the medical supervision only. List of drugs under schedule G: Aminopterin Hydroxyurea Tretamine; its salts L-Asparaginase Bleomycin Insulin, all types Troxidone Busulphan; its salts [(Lomustine Carbutamide Hydrochloride)] Chlorambucil;its salts Mannomustine; its salts Antihistaminic substances Chlorothiazide and other Mercaptopurine; its salts the following, their salts, derivatives of 1, 2, 4 Metformin; its salts their derivatives, benzothiadiazine Methsuximide salts of their derivatives Chlorpropamide; its salts Mustine, its salts Antazoline Chlorthalidone and other Paramethadione Bromodiphenhydramine derivatives of Phenacemide Buclizine Chlorobenzene compound. Phenformin; its salts Chlorcyclizine 2[(Cis-Platin)] 5-Phenylhydantoin; its Chlorpheniramine Cyclophosphamide; its salts alkyl and aryl derivatives; Clemizole Cyproheptadine 2[(Cytarabine)] its salts Diphenhydramine Daunorubicin Primadone Diphenylpyraline Di-Isopropyl [(Procarpazine Doxylamine Succinate Eluorophosphate Disodium Hydrochloride]) Isothipendyl Stilboestrol Quinthazone Mebhydrolin Napadisylate Diphosphate Sarcolysine Meclozine Phenindamine Doxorubicin Hydrochloride [(Sodium-2- Pheniramine Promethazine Ethacrynic Acid, its salts Mercaptoethanesulfonate] Thenalidine Triprolidine Ethosuximide Tamoxiten Citrate Substances being tetra-N- Glibenclamide Testolactone Subs. derivatives of Hydantoin; its salts; its Thiotepa Ethylene Diamine or derivatives, their salts Tolbutamide Prophylenediamine . Schedule H : This schedule contains the list of the drugs to be sold by retail only in the prescription of a registered medical practitioner (RMP) List of drugs under schedule H: Abacavir Auranofin Carteolol hydrochloride Abciximab Azathioprine Carvedilol Acamprosate calcium Aztreonam Cefadroxyl Acebutol hydrochloride Bacampicillin Cefatoxime sodium Aclarubicin Baclofen Cefazolin sodium 92. Albendazole Balsalazide 2[Cefdinir Alclometasone dipropionate Bambuterol Cefepime hydrochloride Actilyse Barbituric acid Cefetamet pivoxil Acyclovir Basiliximab Cefpirome Adenosine Benazepril hydrochloride Cefpodoximepoxetil Adrenocorticotrophic Benidipine hydrochloride Ceftazidime pentahydrate hormone (acth) Benserazide hydrochloride Ceftizoxime sodium] Alendronate sodium Betahistine dihydrochloride Cefuroxime Alopurinol Bethanidine sulphate Celecoxib Alphachymotrypsin Bezafibrate Centchroman 2[Alprazolam Bicalutamide Centbutindole Alprostadil Biclotymol monohydrate Centpropazine Amantadine hydrochloride lactate Cetirizine hydrochloride Amifostine Bifonazole 2[Chlordiazepoxide Amikacin sulphate Bimatoprost Chlormezanone Amiloride hydrochloride 21. Biperiden hydrochloride Chlorpromazine Amineptine Biphenyl acetic acid Chlorzoxazone Aminoglutethimide Bitoscanate Ciclopiroxolamine Amino salicylic acid Bleomycin Cimetidine Amiodarone hydrochloride Primonidine tartrate Cinnarizine Amitriptyline Bromhexine hydrocloride Ciprofloxacin hydrochloride Amlodipine besylate Bromocriptine mesylate Cisplatin Amoscanate Budesonide Citalopram hydrobromide Amoxopine Bulaquine Clarithromycin Amrinonelactate Bupivacaine hydrochloride Clavulanic acid Analgin Bupropion Clidiniumbromide Androgenic anabolic, Buspirone Clindamycin oestrogenic & progestational Butenafine hydrochloride Clobazam substances Butorphanol tartrate Clobetasol propenate Antibiotics Cabergoline Clobetasone 17-butyrate Apraclonidine Calcium dobesilate 2[Clofazimine] Aprotinin Candesartan Clofibrate Organic compound of arsenic Capecitabine Clonazepam Arteether Captopril Clonidine hydrochloride Artemether Carbidopa Clopamide Artesunate Carbocisteine Clopidogrel bisulphate Articaine hydrochloride Carboplatin Clostebolacetate Atenolol Carboquone Clotrimazole Atracurium besylate injection Carisoprodol Clozapine Atorvastatin L-carnitine 2[Codeine] Colchicine 2[Ethionamide] Hepatitis b. Vaccine Corticosteroids Etidronate disodium Hyaluronidase Cotrimoxazole Etodolac Hydrocorisone 17-butyrate Cyclandelate Etomidate Hydrotalcite Cyclosporins Etoposide Hydroxizine Daclizumab Exemestane Ibuprofen Danazole Famciclovir Idebenone Dapsone Famotidine Indapamide Desloratadine Fenbendazole Imipramine Desogestrol Fenofibrate Indinavir sulphate Dexrazoxane Fexofenadine Indomethacin Dextranomer Finasteride Insulin human Dextropropoxyphene Flavoxate hydrochloride Interferon 2[Diazepam] 5-fluorouracil Intravenous fat emulsion Diazoxide Fludarabine Iobitridol Diclofenac sodium/potassium Flufenamic acids Iohexol Dicyclomin hydrochloride Flunarizine hydrochloride Iopamidol Didanosine Fluoxetine hydrochloride Iomeprol Digoxine Flupenthixol Iopromide Dilazep hydrochloride Fluphenazine enanthate and Irbesartan Diltiazem decanoate Irinotecan hydrochloride Dinoprostone Flurazepam Iron preparation for parenteral 2[Diphenoxylate, its salts] Flurbiprofen use Dipivefrin hydrochloride Flutamide Isepamicine Di-sodiumpamidronate Fluticasone propionate Isocarboxside Disopyramide Fluvoxamine maleate Isoflurane Docetaxel Formestane Isonicotnic acid hydrazine and Domperidone Fosfestril sodium other-hydragine derivatives of Donepezil hydrochloride Fosinopril sodium isonicotinic acid Dopamine hydrochloride Fossphenytoin sodium Isosorbide dinitrate/ Dothiepin hydrochloride Fotemustine mononitrate Doxapram hydrochloride Gabapentin Isotretinoin Doxazosin mesylate Galanthamine hydrobromide Isoxsuprine Doxepin hydrochloride Galamine, its salts, its Itopride Doxorubicin hydrochloride quaternary compound Ketoconazole Drotrecogin-alpha Gancyclovir Ketoprofen Ebastine Ganirelix Ketorolactromethamine Econozole Gatifloxacin Labetalol hydrochloride Efavirenz Gemcitabine Lacidipine Enalapril meleate Gemfibrozil Lamivudine Enfenamic acid Gemtuzumab Lamotrigine Epinephrine Genodeoxycholic acid Latanoprost Epirubicine Gliclazide Lefunomide Eptifibatide Glimepiride Lercanidipine hydrochloride Ergot, alkaloids of whether Glucagon Letrozole hydrogenated or not, their Glycopyrrolate Leuprolide acetate homologoues, salts Glydiazinamide Levamesole Esomeprazole Goserelin acetate Levarterenol Estradiol succinate Granisetron Levobunolol Estramustine phosphate 182. Guanethidine Levocetirizine Etanercept Gugulipid Levodopa Ethacridine lactate Halogenated 2[Levofloxacin] 2[Ethambutol hydrochloride] hydroxyquinolines Levovist Ethamsylate Haloperidol Lidoflazine Ethinyloestradiol Heparin Linezplid Lithium carbonate Naproxen Pepleomycin Lofepramine decanoate Narcotics drugs listed in Phenelzineh sulphate Loperamide Narcotic Drugs & Phenobarbital Lorazepam Psychotropic Substances Act, Phenothiazine, derivatives of Losartan potassium 1985 and salts of its derivatives Loteprednol Natamycin Phenylbutazine Lovastatin Nateglinide Pimozide Loxapine N-butyl-2-cyanoacrylate Pindolol Mebendazole Nebivolol Pioglitazone hydrochloride Mebeverine hydrochloride Nebumetone Piracetam Medroxyprogesterone acetate Nelfinavir mesilate Piroxicam Mefenamic acid Netilmicin sulphate Pituitory gland, active Mefloquine hydrochloride Nevirapine principles of, not otherwise Megestrol acetate Nicergoline specified in this schedule and Meglumine iocarmate Nicorandil their salts Melagenina Nifedipine Polidocanol Elitracenhydrochloride Nimesulide Polyestradiol phosphate Meloxicam Nimustine hydrochloride Poractant alfa Mephenesin, its esters 2[Nitrazepam] Praziquantel Mephentermine Nitroglycerin Prednimustine iothalamates 2[Meropenam] Norethisterone enanthate Prednisolone stearoylglycolate Mesterolone Norfloxacin Prenoxdiazinhydro-chloride Metaxalone Octylonium bromide Promazine hydrochloride Methicillin sodium Ofloxacin Promegestone Methocarbamol Olanzapine Propafenon hydrochloride Methotraxate Omeprazole Propanolol hydrochloride 416. Metoclopramide Ornidazole Propofol Metoprolol tartrate Orphenadrine Protristyline hydrochloride Metrizamide Orthoclone sterile 2[Pyrazinamide] Metronidazole Oxazepam Pyrvinium Mexiletine hydrochloride Oxazolidine Quetiapine fumerate Mianserin hydrochloride Oxcarbazepine Quinapril Miconazole Oxethazaine hydrochloride Quinidine sulphate 2[Midazolam] Oxiconazole Rabeprazole Mifepristone Oxolinic acid Racecadotril Milrinone lactate Oxprenolol hydrochloride Raloxifene hydrochloride Miltefosine Oxybutynin chloride Ramipril hydrochloride Minocycline Oxyfedrine Ranitidine Minoxidil Oxymetazoline Rauwolfia, alkaloids of, their Mirtazapine Oxyphenbutazone salts, derivatives of the Misoprostol Oxytocin alkaloids or rauwolfia Mitoxantrone hydrochloride Ozothine Reboxetine Mizolastine Paclitaxel Repaglinide Moclobemide Pancuronium bromide Reproterol hydrochloride Mometasone furoate Pantoprazole Rilmenidine Montelukast sodium Para-amino benzene Riluzone Morphazinamide sulphonamide, its salts & Risperidone hydrochloride derivatives Ritonavir Mosapride Parp-amino salicylic acid, its Ritodrine hydrochloride 2[Moxifloxacin] salts, its derivatives Rituximab Mycophenolate mofetil Parecoxib Rivastigmine Nadifloxacin Paroxetine hydrochloride Rocuronium bromide