Functional Biochemistry Clinical Reference Guide Chris Astill-Smith, DO, ND, DIBAK Casey Reardon, DC Credits Contact information Chris Astill-Smith Epigenetics International, Ltd. The Old Coach House 21 Church Street Market Lavington Devizes, Wiltshire SN10 4DU Phone: 01380 800105 Email: [email protected] www.epigenetics-international.com Casey Reardon Email: [email protected] www.reardonchiropractic.com Copyright 2008-2012 Casey Reardon All Rights Reserved This manual cites information from the following sources: Guyton’s Physiology Harper’s Biochemistry Applied Kinesiology Synopsis 2nd Edition by David Walther, DC, DIBAK A New Earth by Eckart Tolle Water Crystal Healing by Massuro Emoto Power Vs Force by David Hawkins The Linus Pauling Institute (lpi.oregonstate.edu) Common Glandular Dysfunction by Walter Schmitt, DC, DIBAK, DABCN Healing Without Medication by Robert Rister Notes from the following seminars make up this manual: Omega System 1-10 Developing a Total Nutritional Profile Ear, Nose, Throat, Mouth Adrenal Exhaustion Male and Female Hormones Parasites Itchy Patient Menstrual Disorders Toxicity pH Acid Base Balance Children Updates 2007 and 2008 Sugar Metabolism Annual Conference 2008 Arthritis Belgium 2009 Preliminary Procedures Sugar and Arthritis Genito-Urinary System Neurobehavioral Disorders Annual Update 2009 Memory Annual Update 2010 Common Respiratory Ailments Disclaimer The material in this book is for educational purposes only. It is always the treating doctor’s responsibility to determine what treatment a patient needs. The methods covered in this book are not meant to diagnose, treat, prevent, or cure any diseases and should always be used in addition to, not instead of, standard examination procedures. No doctor- patient relationship is established by this book. Procedure Outline Preliminary Procedures 1. Identify strong and weak muscles 2. TL to GV 20 weakens a. If no i. Inspiration and expiration open – cranial ii. Inspiration or expiration open – body structure iii. Identify B+E point that opens GV 20 – Rub 30 secs while patient TLs GV 20 b. If yes i. Inspiration and expiration close – cranial ii. Inspiration or expiration close – body structure iii. Identify B+E point that closes GV 20 – Rub 30 secs while patient TLs GV 20 3. TL to eyes weakens a. Deep cranial fault 4. Tapping patellar reflex does not weaken opposite Latissmus Dorsi and Rectus Femoris (check both sides) a. Correct body structure superior to inferior 5. TL to now time Alarm Point does not weaken a. Correct Body Clock 6. Identify primary and secondary eye cone colors a. Red, Green, Blue Hemisphere Dominance 7. Challenge for underfunctioning hemisphere using goggles or hands over eyes a. If neither side weak – adjust occiput, C1, or other structural fault b. If left or right weakens challenge with brain nuclei i. midbrain, hindbrain, cerebellum, cortex (parietal, temporal, occipital, frontal) c. Remove goggles – TL brain nuclei reflex points on head bilaterally (TL weak side first) d. Use EID / BID to identify cause(s) of underfunctioning nuclei e. Correct as indicated and repeat until both hemispheres are corrected Energy 8. Mg-ADP weakens a. If yes – Test Glycolysis, Ctric Acid Cycle, Electron Transport Chain nutrients b. If no – Does Mg-ADP weaken with TL to umbilicus? i. If yes – weakness negated by tissue extracts 1. Adrenal Cortex, Adrenal Medulla, Pineal, Thymus 2. Challenge with Snowdrops a. If weakens – gland is hyper b. If strengthens – gland is hypo 3. Determine key nutrient(s) c. Scale of ATP Energy d. Scale of Vital Energy e. Scale of Metabolism Genomics 9. Nucleotide base (A, C, T, G, U) weakens a. Identify SNIP – Test other bases for strengthening b. Composites: Vitamin, Coenzyme, Mineral, Sat Fat, Unsat Fat, Probiotic, Amino Acid, Saccharide i. Narrow composites to the specific nutrient c. Test Compounds: Multiple Vitamin / Mineral, B Complex, Nutrient Phase 1+2, Homocysteine Formula, Ostecaps d. Test Spices e. Scale of Health f. Scale of Wobble Wellness, Methylation 10. Sodium Lauryl Sulfate weakens a. Scale of Wellness b. Challenge against: Multiple Vitamin / Mineral, Nutrient Phase 1+2, Ostecaps, Homocysteine Formula, B Complex 11. Test Methionine, SAM, SAH, Homocysteine, and Cystathione for weakening and strengthening a. Identify effects of methylation defect on adjacent cycles b. Identify nutrient to restore methylation cycles c. Scale of Biochemistry d. Check nutrients against Prospective Age B+E Point Evaluation, Neurotransmitters 12. Determine Primary Meridian a. Test corresponding Neurotransmitter i. If positive – Determine nutrients needed to make or break down Endocrine b. Test corresponding Hormone i. If positive – Determine nutrients needed to make or break down Diagnostic Entry c. Determine Optimal Diagnostic Entry (EID vs BID) d. Determine cause of meridian imbalance using Diagnostic Entry i. Left and Up – Nutritional Deficiency 1. Composites: Vitamin, Coenzyme, Mineral, Probiotic, Sat Fat, Unsat Fat, Amino Acid, Saccharide 2. Narrow composites to the specific nutrient ii. Straight Left – Toxicity 1. Chemical, Radiation, Toxic Metal 2. Determine remedy 3. Identify Source – Verbal Challenges iii. Left and Down – Structure iv. Right and Up – Dehydration 1. Determine amount of water needed v. Straight Right – Exercise 1. Scale of Fitness 2. Verbal Challenge for optimal exercise, times per week, and length per time 3. Aerobic Challenge 4. Anaerobic Challenge vi. Right and Down – Allergy 1. Identify offending food or drink 2. Rub B+E point that negates weakness with food in mouth or vial on patient 3. Identify chemical mediators (kinin, histamine, PG, LT) and nutrients to metabolize vii. Side to side – Energy 1. Glucose, Glycolysis, CAC, ETC nutrients 2. Kundalini meridian – cortex, medulla, pineal, thymus viii. Circumduction – Infection 1. Bacteria, Virus, Post Virus, Parasite, Fungus 2. Determine remedy ix. Eyes crossed on nose – Sleep 1. Determine optimal length of time to sleep 2. Does patient strengthen to melatonin or weaken to cortisol or adrenaline at nighttime alarm point (TW, GB, LV, LU)? a. If yes – Identify nutrients to correct Emotional 13. Eyes closed weakens a. “The optimal emotional release for me to perform on you is… i. …To release the unconscious emotions” strengthens 1. TL to B+E point strengthens eyes closed 2. Give patient affirmation to release emotion ii. …The Love Challenge” strengthens 1. Patient weakens to “I am loved”, “I am loving”, or “I am lovable” 2. Repeat the weakening statement 20 times every night Preliminary Procedures 14. Is gait pattern is intact when standing? If not: a. Identify and correct structural fault b. Patient jumps on heels 6 times c. Repeat until correct gait pattern is maintained Energy 15. Scale of Vitality was less than 1000 a. Patient looks at light box with color corresponding to primary meridian for 15 minutes b. Patient listens to music corresponding to primary meridian Biochemical Flowchart Key Substrate Mineral Cofactor, Vitamin Coenzyme, or other substance that is needed for the conversion Toxin or other substance that blocks the conversion Product Synthase = enzyme to convert substrate to product Product / Substrate 2 Mineral Cofactor, Vitamin Coenzyme, or other substance that is needed for the conversion Toxin or other substance that blocks the conversion Product 2 Synthase = enzyme to convert substrate 2 to product 2 Product 2 Substrate weakens and product strengthens = underactive enzyme Test substances to enhance conversion of Substrate to Product Substrate strengthens and product weakens = Overactive enzyme Test substances to convert Substrate 2 to Product 2 When substrate is low and product is high, it may be appropriate to test substances to block the conversion of substrate to product, such as herbs in a case of low testosterone. In most cases, these substances are toxins that should not be supplemented and the best remedy is to enhance the conversion of Substrate 2 to Product 2. GV 20 Located at the highest point on the top of the head Related to the Hypothalamus Traditional Chinese Acupuncture calls it “The Cure of 100 Diseases” Governing Vessel 20 can be used to test anything including supplements, flower remedies, homeopathics, or anything else where a weak muscle is needed. Anything that strengthens GV 20 will benefit the person, though it can’t be said, based on the test, whether it will improve their health by 1% or 100%. If something does not strengthen GV 20, it will not benefit the patient. In a well neurologically organized person, GV 20 will weaken unless the person has no stresses on their body. If GV 20 does not weaken, the patient is either perfect, just took their supplements, or is neurologically disorganized. GV 20 Procedure 1. TL to GV 20 weakens a. Inspiration and expiration strengthen Æ Superficial Cranial Fault i. Using B+E points a. TL B+E points until one strengthens GV 20 – indicates primary B+E point b. Rub this point bilaterally for 30 seconds with TL to GV 20 ii. Mechanical Correction a. Respiratory adjust b. TL technique c. All in one technique b. Inspiration or expiration strengthen Æ Ascending Fault (see next section on Biomechanics) 2. TL to GV 20 does not weaken a. Inspiration and expiration weaken Æ Superficial Cranial Fault i. Using B+E points a. TL B+E points until one weakens GV 20 – indicates primary B+E point b. Rub this point bilaterally for 30 seconds with TL to GV 20 ii. Mechanical Correction a. Respiratory adjust b. TL technique c. All in one technique b. Inspiration or expiration weaken Æ Ascending Fault (see next section on Biomechanics) c. RNA or DNA open GV 20 i. 2-3 capsules a day for 2-3 weeks ii. Cut the dose in half if the patient experiences any bloating (supplement is made from yeast) iii. Open GV 20 from DNA or RNA is negated by DNA or RNA Polymerase, If yes: a. Test Zinc d. 2 hand TL anywhere on the trunk weakens i. One hand contralateral TL on trunk opens GV 20 ii.