Microarray Data from: Mariadason et al. A gene expression profile that defines colon cell maturation in vitro. Cancer Research , August 15, 2002. Caco-2 time course: Normalized gene expression ratios. Caco-2 cells at Day 0 (Control) versus Caco-2 cells at Days 5, 14 or 21. Normalized expression data for 13,638 genes with significant expression above background Genbank Spot # Gene Name Day 0 vs 2 Day 0 vs 5 Day 0 vs 14 Day 0 vs 21 Accession # 1 AA043412 peptidylprolyl isomerase C (cyclophilin C) 0.630 1.322 0.950 1.096 2 W46433 similar to glucosamine-6-sulfatases 0.508 1.386 0.921 0.991 3 H46001 synaptotagmin 7 0.511 1.624 0.991 1.174 4 AA465378 ESTs, Highly similar to S17597 Ig delta chain [H.sapiens] 0.771 1.457 1.052 1.098 5 R42880 ESTs 0.743 1.386 0.979 1.137 6 T40444 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.968 1.044 0.820 0.990 7 AA101348 dendritic cell protein 0.971 1.016 0.654 0.630 8 T61525 ESTs, Highly similar to EA8.5 GENE PROTEIN [Bacteriophage 1.085 0.916 1.006 1.013 lambda] 9 AA028921 SMA5 1.460 0.990 1.321 1.625 10 AA700048 gene from NF2/meningioma region of 22q12 0.871 0.651 0.644 0.673 11 N63192 EST, Highly similar to PNMT_HUMAN 0.845 1.129 0.868 0.926 PHENYLETHANOLAMINE N-METHYLTRANSFERASE [H.sapiens] 12 N53362 ESTs 1.121 1.100 0.886 1.093 13 W74802 ESTs 0.925 1.160 0.802 1.112 14 R06746 ESTs, Weakly similar to T12A2.1 [C.elegans] 0.748 1.342 0.909 1.125 15 AA149640 ESTs 0.816 0.928 1.108 1.088 16 T87132 ESTs, Highly similar to sodium/hydrogen exchanger isoform 5 0.715 0.943 0.938 0.955 [H.sapiens] 17 N94060 ESTs, Weakly similar to KIAA0806 protein [H.sapiens] 0.849 0.841 0.810 0.838 18 R98591 ESTs 1.029 0.934 1.036 1.076 19 T97430 ESTs 0.994 1.093 0.963 0.983 21 T95268 J domain containing protein 1 isoform a (JDP1) mRNA, complete 1.138 1.334 1.068 1.038 cds 22 AA460981 golgi autoantigen, golgin subfamily a, 4 1.087 0.676 0.943 1.073 23 R08816 acid phosphatase 5, tartrate resistant 1.136 1.072 0.801 1.012 24 AA424516 cDNA: FLJ21930 fis, clone HEP04301, highly similar to 1.320 1.065 1.071 1.111 HSU90916 Human clone 23815 mRNA sequence 25 AA434024 lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.474 0.971 0.761 0.743 26 R45056 hypothetical protein PRO1847 0.605 0.681 0.601 0.516 28 AA039547 ribosomal protein S5 pseudogene 1 0.464 1.590 0.973 1.109 29 H30286 transcriptional unit N143 0.509 1.338 0.840 1.184 Genbank Spot # Gene Name Day 0 vs 2 Day 0 vs 5 Day 0 vs 14 Day 0 vs 21 Accession # 30 AA459013 X-ray repair complementing defective repair in Chinese hamster 0.800 1.045 0.831 0.805 cells 3 31 AA479106 hypothetical protein FLJ10637 0.590 0.939 0.710 0.841 32 T40467 EST 1.001 1.213 0.780 1.149 33 AA598797 histone acetyltransferase 1.019 0.892 0.865 0.809 34 AA425769 Alg5, S. cerevisiae, homolog of 1.112 0.608 0.664 0.761 35 H39018 synaptotagmin 5 1.222 1.422 1.244 1.180 36 N59115 nuclear receptor subfamily 5, group A, member 2 1.256 1.803 1.358 1.225 37 AA481464 peptidylprolyl isomerase B (cyclophilin B) 1.029 1.211 0.903 1.000 38 W72231 ESTs 1.048 1.437 0.911 1.041 39 W86002 ESTs, Weakly similar to ALU1_HUMAN ALU SUBFAMILY J 0.933 1.163 0.806 1.125 SEQUENCE CONTAMINATION WARNING ENTRY [H.sapiens] 40 AA150422 cDNA: FLJ23462 fis, clone HSI08475 0.963 1.466 0.925 1.046 41 AA485349 cDNA FLJ13663 fis, clone PLACE1011646, highly similar to 0.850 0.969 0.813 1.067 clone 25059 mRNA sequence 42 AA464143 cDNA: FLJ22637 fis, clone HSI06677 0.706 0.827 0.835 0.946 43 N94264 ESTs 0.952 0.953 0.901 1.045 44 R98905 ESTs 0.889 1.177 1.006 0.939 45 T97887 ESTs 1.104 1.219 0.864 1.152 46 H64260 H91620p protein 1.178 1.128 1.080 1.095 47 R01796 androgen induced protein 1.581 2.135 2.002 2.424 48 AA287196 tetraspan 3 1.420 1.235 1.201 1.479 49 H05768 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 0.859 0.725 0.671 0.740 42kD 51 R19889 DAZ associated protein 2 1.192 1.346 1.296 1.452 52 AA427688 protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 1.004 0.987 0.888 1.080 65), alpha isoform 54 AA284245 ESTs, Weakly similar to /prediction=(method:""genefinder"", 0.512 1.369 0.864 1.124 version:""084"", score:""23.69"")~/prediction=(method:""genscan"", version:""1.0"", score:""39.63"")~/match=(desc:""SD07039.5prime SD Drosophila melanogaster Schneider L2 cell culture pOT2 Drosop 55 H68370 putatative 28 kDa protein 0.432 0.938 0.628 0.912 56 AA458932 clone 23783 mRNA sequence 0.492 0.893 0.714 0.741 57 AA424754 KIAA1214 protein 0.717 1.259 0.935 1.017 58 T50137 ESTs 0.924 1.239 0.948 1.015 59 W69379 cDNA DKFZp586D0923 (from clone DKFZp586D0923) 1.124 1.189 0.946 0.985 Genbank Spot # Gene Name Day 0 vs 2 Day 0 vs 5 Day 0 vs 14 Day 0 vs 21 Accession # 60 H19227 alpha2,3-sialyltransferase 1.289 1.129 0.890 1.110 61 AA016290 retinoblastoma-binding protein 6 0.979 0.866 0.839 0.777 62 N90109 nucleolin 1.177 0.979 1.019 0.628 63 R95962 paired box gene 6 (aniridia, keratitis) 1.182 1.174 0.918 1.019 64 AA130117 clone HH114 unknown mRNA 1.034 1.066 0.772 0.882 65 N52651 cDNA: FLJ22474 fis, clone HRC10568 1.184 1.383 0.879 1.191 66 W89128 ESTs 1.143 0.972 0.806 1.066 67 AA029312 cDNA DKFZp434D0935 (from clone DKFZp434D0935) 0.924 0.881 0.683 0.946 68 N34362 regulator of G-protein signalling 5 0.881 0.990 0.740 1.035 69 N94274 ESTs 1.059 1.132 0.873 1.105 70 H48445 ESTs 0.961 0.927 0.999 0.930 71 T97910 clone IMAGE:121558 mRNA sequence 1.113 1.033 0.861 1.056 72 N77326 cDNA: FLJ21905 fis, clone HEP03764 1.283 1.598 1.289 1.725 73 H81104 ESTs 1.120 1.320 1.004 1.139 74 AA456028 Rab geranylgeranyltransferase, beta subunit 0.955 0.916 0.708 0.861 75 H85355 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.024 1.023 0.896 0.996 76 H98636 tumor necrosis factor receptor superfamily, member 5 1.206 1.079 0.941 1.003 77 AA490493 centaurin beta2 0.830 0.848 0.796 0.950 80 AA022558 cDNA: FLJ22120 fis, clone HEP18874 0.452 1.427 0.786 1.145 81 H97691 paired box gene 3 (Waardenburg syndrome 1) 0.626 1.288 0.876 1.085 82 AA459244 cofactor required for Sp1 transcriptional activation, subunit 9 0.673 1.278 0.859 1.036 (33kD) 83 R40031 cell recognition molecule Caspr2 0.787 1.331 0.874 1.200 84 T50974 ESTs 0.985 1.221 0.852 1.009 85 AA434135 Cip1-interacting zinc finger protein 1.681 1.132 0.845 0.751 86 H15685 catalase 1.548 1.425 1.121 1.148 87 W90116 nuclear mitotic apparatus protein 1 1.246 0.895 0.863 0.836 88 W69954 allograft inflammatory factor 1 1.142 1.077 1.022 0.738 89 AA485377 v-fos FBJ murine osteosarcoma viral oncogene homolog 1.284 1.308 0.904 1.012 90 AA026167 ESTs 1.311 1.345 0.752 1.105 91 N31952 cDNA: FLJ21938 fis, clone HEP04471, highly similar to 0.923 0.872 0.628 0.645 HST000014 mRNA full length insert cDNA clone EUROIMAGE 195423 92 R07128 ESTs 1.033 0.963 0.708 1.011 93 AA443116 KIAA1224 protein 1.684 0.905 0.779 1.271 94 AA458487 eukaryotic translation initiation factor 4 gamma, 1 1.096 0.891 0.823 1.069 95 N99514 ESTs 1.336 0.951 0.823 1.102 96 H89843 ESTs 1.123 0.963 1.039 0.886 97 R09411 ESTs 1.156 1.117 0.858 1.039 Genbank Spot # Gene Name Day 0 vs 2 Day 0 vs 5 Day 0 vs 14 Day 0 vs 21 Accession # 98 T97637 ESTs 1.230 1.267 0.918 1.057 99 H50667 uncharacterized bone marrow protein BM042 1.281 2.041 1.274 1.386 100 AA458533 forkhead box J1 0.792 1.025 0.944 0.910 102 H13577 ectonucleoside triphosphate diphosphohydrolase 1 1.148 1.285 1.143 1.232 103 H60460 KIAA0022 gene product 1.109 1.250 1.224 1.504 106 AA039640 wee1+ (S. pombe) homolog 0.499 1.082 0.861 1.009 107 AA758354 immunoglobulin lambda gene locus DNA, clone:61D6 0.533 1.467 0.867 0.961 108 AA490998 transport-secretion protein 2.2, 0.675 0.969 0.789 0.996 109 R60711 KIAA1091 protein 0.812 1.094 0.722 0.883 110 T54603 ESTs 1.138 1.140 0.844 1.004 111 AA130866 hypothetical protein FLJ10727 1.493 1.436 0.989 1.034 112 AA485867 macrophage receptor with collagenous structure 1.255 1.354 0.992 1.142 113 AA676322 metal-regulatory transcription factor 1 1.281 1.260 0.977 1.054 114 AA425823 sterol regulatory element binding transcription factor 1 1.121 1.160 0.975 0.903 115 AA700876 orosomucoid 1 2.334 4.607 2.444 3.427 116 N67972 ESTs 1.205 1.103 0.788 1.146 117 N51843 ESTs 1.286 1.097 0.759 0.939 118 AA115559 DKFZP566K023 protein 1.382 0.897 0.683 0.997 119 AA464195 hypothetical protein DKFZp434D0412 1.436 0.958 0.808 1.260 120 AA120816 hypothetical protein 1.140 0.790 0.630 0.752 121 W01645 ESTs 1.415 1.350 0.932 1.238 122 R99386 ESTs 1.058 1.548 1.043 0.989 123 T98075 clone IMAGE:121736 mRNA sequence 1.385 0.991 0.965 1.038 124 T64956 KIAA1268 protein 1.348 1.217 0.889 1.090 125 N77514 CGI-150 protein 1.033 0.850 0.742 0.787 127 AA447528 ubiquitination factor E4A (homologous to yeast UFD2) 1.000 1.157 1.179 1.110 128 AA434483 CD34 antigen 1.135 1.162 0.978 1.017 129 AA236617 Rac/Cdc42 guanine exchange factor (GEF) 6 1.070 1.083 1.118 0.989 132 N54456 ALEX3 protein 0.633 2.095 1.145 1.151 133 AA629900 replication protein A1 (70kD) 0.553 1.260 0.768 1.104 134 AA489073 hypothetical protein 23851 0.839 1.245 0.754 1.135 135 AA418729 cDNA: FLJ22318 fis, clone HRC05303 1.020 1.080 0.978 1.019 136 T52152 hypothetical protein FLJ10749 0.893 0.585 0.562 0.562 137 AA121360 hypothetical protein FLJ20277 1.405 1.208 0.973 1.063 138 AA187349 ferredoxin 1 1.481 1.357 1.039 1.353 139 AA629909 glycyl-tRNA synthetase 1.023 0.819 0.656 0.645 140 N45979 SH3 domain protein 1B 1.143 1.134 0.860 1.024 141 AA430382 nucleoside phosphorylase 1.194 1.230 0.882 0.879 142 N59871 ESTs 1.001 1.001 1.002 0.925 Genbank Spot # Gene Name Day 0 vs 2 Day 0 vs 5 Day 0 vs 14 Day 0 vs 21 Accession # 143 R89828 ESTs, Moderately similar to ALU7_HUMAN ALU