Supplementary Online Content Hedström AK, Hillert J, Olsson T, Alfredsson L. Alcohol as a modifiable lifestyle factor affecting multiple sclerosis risk. JAMA Neurol. Published January 6, 2014. doi:10.1001/jamaneurol.2013.5858 eAppendix. Questions on alcohol consumption in EIMS. This supplementary material has been provided by the authors to give readers additional information about their work. © 2013 American Medical Association. All rights reserved. Downloaded From: https://jamanetwork.com/ on 09/30/2021 eAppendix Questions on alcohol consumption in EIMS 1. During the last 12 months, have you drunk at least one glass of export beer, spirits, wine or fortified wine? No Yes If “yes”, approximately how much alcohol did you drink last week? Export beer/medium-strength beer (bottle 33 cl, can 45 cl) Wine (glass 20 cl, half a bottle 37 cl, whole bottle 75 cl) Fortified wine (glass 5 cl, half a bottle 37 cl, whole bottle 75 cl) Spirits (snaps 5 cl, half a bottle 37 cl, whole bottle 75 cl) 2. How was your alcohol consumption last week? 1. Much less than usual 2. Less than usual 3. Somewhat less than usual 4. As usual 5. Somewhat more than usual 6. More than usual 7. Much more than usual 3. Compared to today, how was your alcohol consumption 5 years ago? 1. Much less than usual 2. Less than usual 3. Somewhat less than usual 4. As usual 5. Somewhat more than usual 6. More than usual 7. Much more than usual Questions on alcohol consumption in GEMS 1. Do you drink, or have you drunk, alcoholic drinks? “Alcoholic drinks” refer to export beer/medium‐strength beer, alcoholic strong cider, wine, fortified wine, and spirits. Yes No If No, proceed to question 69 2. If “Yes”, approximately how many glasses did you drink last week? State 0 if you had none. One “glass” means: 50 cl export beer/medium‐strong bear 33 cl strong bear 10‐15 cl white or red wine © 2013 American Medical Association. All rights reserved. Downloaded From: https://jamanetwork.com/ on 09/30/2021 5‐8 cl fortified wine 4 cl spirits, for example whisky Number of “glasses” last week 1. Export beer/medium‐strength beer 2. Medium‐strength beer, strong bear, cider 3. Wine 4. Fortified wine 5. Spirits 3. How was your alcohol consumption during the last week? 1. Much lower than usual 2. Lower than usual 3. Somewhat lower than usual 4. As usual 5. Somewhat higher than usual 6. Higher than usual 7. Much higher than usual 4. Approximately, how much alcohol did you drink during an ordinary week in the following age categories? State number of “glasses” below. Try to state an average for each age period up to your current age. State 0 if you did not drink alcohol. One “glass” means: 50 cl export beer/medium‐strong bear 33 cl strong bear 10‐15 cl white or red wine 5‐8 cl fortified wine 4 cl spirits, for example whisky Age 15‐19 years Number of “glasses”/week 1. Export beer/medium‐strength beer 2. Medium‐strength beer, strong bear, cider 3. Wine 4. Fortified wine 5. Spirits Age 20‐29 years Number of “glasses”/week 1. Export beer/medium‐strength beer 2. Medium‐strength beer, strong bear, cider 3. Wine 4. Fortified wine 5. Spirits Age 30‐39 years Number of “glasses”/week 1. Export beer/medium‐strength beer 2. Medium‐strength beer, strong bear, cider © 2013 American Medical Association. All rights reserved. Downloaded From: https://jamanetwork.com/ on 09/30/2021 3. Wine 4. Fortified wine 5. Spirits Age 40‐49 years‐ Number of “glasses”/week 1. Export beer/medium‐strength beer 2. Medium‐strength beer, strong bear, cider 3. Wine 4. Fortified wine 5. Spirits Age 50 years ‐ Number of “glasses”/week 1. Export beer/medium‐strength beer 2. Medium‐strength beer, strong bear, cider 3. Wine 4. Fortified wine 5. Spirits © 2013 American Medical Association. All rights reserved. Downloaded From: https://jamanetwork.com/ on 09/30/2021.