An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_000158515-HmpCyc: Bacteroides sp. 4_3_47FAA Cellular Overview Connections between pathways are omitted for legibility. a dicarboxylate a dicarboxylate an amino an amino phosphate + 1-(β-D K phosphate phosphate + putrescine an amino a C4- a lipopolysaccharide acid an amino an amino acid a lipopolysaccharide Co 2+ H + H glutamate 2+ 2+ + + phosphate phosphate 2+ ribofuranosyl) + 2+ 2+ + acid chromate a sugar a nucleoside a polysaccharide a polyamine Mo Mo a nucleotide ammonium Na D-glucose (S)-lactate acid acid D-glucose phosphonate L-rhamnose Na Zn a polysaccharide K chromate Mg 2+ Mg H spermidine dicarboxylate nicotinamide Mg predicted cytochrome K(+)- ABC V-type ATP RS13810 RS18515 d ubiquinol RS05675 RS07820 RS17495 RS08365 RS01225 RS04580 RS13825 RS17515 RS08580 RS02555 RS01075 RS12570 RS06840 transporting RS14340 RS18800 RS17855 RS01585 RS08880 RS02590 RS01795 RS17480 RS15915 RS16540 RS13415 RS07715 RS12575 RS15225 RS17880 RS20900 RS01310 RS08475 RS24130 RS05670 RS09240 RS17905 RS20025 RS01645 RS15600 transporter synthase oxidase ATPase of phosphate a lipopolysaccharide a lipopolysaccharide + putrescine a sugar 6- a C4- phosphate phosphate 1-(β-D Co 2+ H an amino chromate a nucleoside a polysaccharide a polyamine Mo 2+ Mo 2+ a nucleotide ammonium Na + an amino D-glucose (S)-lactate an amino an amino D-glucose phosphonate an amino L-rhamnose Na + Zn 2+ a polysaccharide K + chromate Mg 2+ Mg 2+ H + H + RS17120 H + spermidine phosphate dicarboxylate glutamate phosphate phosphate ribofuranosyl) Mg 2+ H + acid O UQH K + acid acid acid acid 2 2 nicotinamide phosphate UQ H O a dicarboxylate a dicarboxylate 2 RS16860 Cofactor, Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis Carbohydrate Degradation Aminoacyl-tRNA Charging Glycolysis Aromatic Compound H + RS15245 H + Degradation uridine methyl-esterified a [protein]- an organic a sophorosyloxyfatty an α-D- p-nitrophenyl-α-D- a single- a single α-amylose 2+ a colanic acid lipid A-core melibionate cob(II)yrinate a,c- D-galactose degradation I (Leloir pathway) carbonic acid protoporphyrin IX Mg homogalacturonan glucuronoside galactopyranoside [2Fe-2S] iron-sulfur cluster biosynthesis superpathway of tetrahydrofolate biosynthesis superpathway of menaquinol-8 biosynthesis I menaquinol-9 biosynthesis superpathway of thiamine diphosphate biosynthesis I Secondary Metabolite Biosynthesis tRNA charging glycolysis I (from glucose 6-phosphate) L-rhamnose degradation I L-cysteine hydroperoxide acid O(6'')-acetate stranded RNA stranded DNA diamide biosynthesis I superpathway of demethylmenaquinol-8 biosynthesis I protocatechuate uridine kinase: carbonic 1,4-alpha-glucan- peroxiredoxin: acetylesterase: alpha-galactosidase: alpha-galactosidase: polyribonucleotide exodeoxyribonuclease L-arabinose degradation II (ortho- BSFG_RS03525 BSFG_RS03525 (early cobalt insertion) β-D-galactose α BSFG_RS02375 anhydrase: branching protein: ahpC BSFG_RS04735 nucleotidyltransferase: pnp VII: BSFG_RS15480 xseB D-glucopyranose 6-phosphate -L- degradation I cleavage pathway) L-cysteine desulfurase chorismate chorismate demethylmenaquinol-9 cys autoinducer AI-2 biosynthesis I arg arginine-- BSFG_RS04065 BSFG_RS10610 Mg- E. coli M MeOH a homogalacturonan a sophorosyloxyfatty an alcohol D-glucopyranuronate D-gluconate α-D-galactose 4-nitrophenol D-galactopyranose a nucleoside a single- a single-stranded a ribonucleoside uroporphyrinogen-III GTP demethylmenaquinone preQ biosynthesis tRNA ligase: galactose-1- rhamnopyranoseL-rhamnose UMP LPS an alcohol a protein disulfide acetate 0 protocatechuate CO H O protoporphyrin acid diphosphate stranded RNA oligodeoxyribonucleotide 5'-monophosphate isochorismate L-arabinopyranose 2 2 amylopectin cysteine isochorismate methyltransferase: cysteine BSFG_RS20800 an L-arginyl- glucose-6-phosphate epimerase: mutarotase: synthase: SAM L-arabinose GTP synthase: BSFG_RS06940 [tRNA Arg ] isomerase: BSFG_RS02585 rhaM desulfurase: desulfurase: isomerase: + ATP + precorrin-1 cyclohydrolase BSFG_RS03130 BSFG_RS03130 menaquinol-9 GTP a tRNA Arg BSFG_RS00645 [+ 2 isozymes] L-rhamnose 3-carboxy-cis H H BSFG_RS12240 BSFG_RS12240 BSFG_RS02605 a glucosylated UTP p-nitrophenyl- 13-sophorosyloxydocosanoate synthase I FolE: folE an [L-cysteine GTP mutarotase: ,cis-muconate glycocholate L-iditol α-D-ribofuranose an acetyl ester canavaninosuccinate a sophorosyloxyfatty a [protein]-L-glutamine serotonin an α-D-galactoside an S-sulfanyl-[L- isochorismate isochorismate D-glyceraldehyde a ThiS sulfur- α-D-galactose L-ribulose glycogenin acid 6',6''-diacetate α-D-glucuronide 6',6''-diacetate CAIR asp 7,8- desulfurase]-S- cyclohydrolase F6P BSFG_RS05135 nucleoside triphosphate alpha-galactosidase: cysteine desulfurase] 3-phosphate carrier protein SAH 7,8- β-L- sorbitol 1,4-alpha-glucan- acetylesterase: argininosuccinate acetylesterase: transglutaminase: acetylesterase: dihydroneopterin 2-succinyl-5- sulfanyl-L-cysteine I FolE: folE ribokinase: pyrophosphohydrolase: BSFG_RS03525 phosphoribosylaminoimidazolesuccinocarboxamide 2-succinyl-5- dihydroneopterin galactokinase: rhamnopyranose dehydrogenase: branching protein: BSFG_RS04735 lyase: argH BSFG_RS04735 BSFG_RS01595 β BSFG_RS04735β 3'-triphosphate 1-deoxy-D- cysteine ThiS BSFG_RS06620 BSFG_RS06775 6 13-[O(2')- -D-glucopyranosyl- -D- synthase: BSFG_RS06935 precorrin-2 enolpyruvyl- enolpyruvyl- 5'-methylthioadenosine/ cysteine-- fructose-1,6- 6-phosphofructokinase: (2-carboxy- BSFG_RS04980 BSFG_RS10610 a sophorosyloxyfatty a [protein] N -[(5-hydroxy-1H a non galactosylated α xylulose-5- desulfurase: adenylyltransferase: 3'-triphosphate cys galK L-rhamnose gly cholate acetate an alcohol fumarate L-canavanine acetate 4-nitrophenol D-glucopyranuronate -D-galactose acetate glucopyranosyloxy]docosanoate SAICAR 6-hydroxy-3- 6-hydroxy-3- adenosylhomocysteine tRNA ligase: bisphosphatase: pfkA L-ribulose 5- 2,5-dihydro- α-D-ribose UMP acid O(6'')-acetate -indol-3-yl)ethyl]-L-glutamine galactose acceptor BSFG_RS12240 BSFG_RS13785 6-carboxytetrahydropterin α isomerase: keto-L-sorbose a glycogen O(6'')-acetate an S-sulfanyl-[cysteine cyclohexene- cyclohexene- phosphate nucleosidase: BSFG_RS20455 -D-galactose phosphate a [ThiI sulfur- a carboxy- synthase QueD: queD an L-cysteinyl- BSFG_RS17275 [+ 2 isozymes] UDP-α-D-glucose BSFG_RS16545 5-oxofuran- 5-phosphate 7,8- 1-carboxylate synthase: BSFG_RS20250 Cys 1-phosphate desulfurase]-[disordered- 1-carboxylate AIR carrier protein]-S- adenylated-[ThiS [tRNA ] L-ribulose-5- 2-yl)-acetate dihydroneopterin synthase: BSFG_RS11550 6-carboxy-5,6,7,8- Cys form scaffold synthase: tyr a tRNA β keto-L-rhamnulose phosphate 4- gamma- 3'-phosphate sulfanyl-L-cysteine sulfur-carrier protein] S-ribosyl-L-homocysteine -D-fructose 1,6-bisphosphate N-acetyl-β-D- uridine 2'3'-cyclic a DNA containing sirohydrochlorin protein] complex menD menD phosphomethylpyrimidine 1-deoxy-D- tetrahydropterin carboxymuconolactone cis-vaccenyl + hydrogen 7,8- myo-inositol DHAP epimerase: D-altropyranose ethylene glycol 2'-deoxyribose L-canavanine monophosphate H NADH an apurinic/ HMG-CoA a homogalacturonan 2-succinyl-5- synthase ThiC: xylulose-5- 2-iminoacetate 7-carboxy-7- decarboxylase: mannosamine acetate peroxide dihydromonapterin a palmitoyl-[acp] a malonyl-[acp] 2-succinyl-5- biosynthesis fructose-1,6- araD arginase: 2',3'-cyclic-nucleotide apyrimidinic site pectate lyase: pelA enolpyruvoyl-6- BSFG_RS13765 phosphate synthase ThiH: S-ribosylhomocysteine deazaguanine BSFG_RS14310 L-fucose lactaldehyde N-acylglucosamine acetylesterase: NADH peroxidase: endonuclease dihydroneopterin hydroxymethylglutaryl-CoA enolpyruvoyl-6- triose-phosphate bisphosphate D-xylulose ribokinase: BSFG_RS07115 2'-phosphodiesterase: pectate lyase: beta-ketoacyl-[acyl-carrier- chorismate hydroxy-3-cyclohexene- synthase: dxs BSFG_RS13780 lyase: BSFG_RS20255 synthase: D-glucopyranose (4,5-dihydro- isomerase: reductase: 2-epimerase: BSFG_RS04735 BSFG_RS02330 III: nth aldolase: folB lyase: BSFG_RS11440 a [cysteine desulfurase]- 7,8- hydroxy-3-cyclohexene- glutamine-- isomerase: aldolase, class II: fba L-rhamnulofuranose 5-phosphate BSFG_RS06620 cis-vaccenyl BSFG_RS17780 6-(hydroxymethyl) BSFG_RS07750 protein] synthase II: fabF 1-carboxylate HMP-P a thiocarboxy- BSFG_RS14480 6-phosphate 5-oxofuran- fucI BSFG_RS21615 BSFG_RS00625 acetate NAD + H O a 3'-terminal a 5'-phospho- glycolaldehyde acetyl-CoA acetoacetate cobalt- S-sulfanyl-[disordered- dihydroneopterin aminodeoxychorismate 1-carboxylate 1-deoxy-D-xylulose inositol-3- tRNA ligase/ BSFG_RS17170 UDP-glucose urea L-canaline alcohol 2 -7,8-dihydropterin an unsaturated pectate 2-iminoacetate [ThiS-Protein] AI-2 [+ 2 isozymes] rhamnulokinase: 2-yl)-acetate 2-deoxy-D-ribose 3'-UMP unsaturated sugar [DNA] a homogalacturonan acyl-carrier protein a 3-oxooctadecanoyl-[acp] sirohydrochlorin form scaffold synthase component bifunctional 5-phosphate 7-carboxy-7- phosphate YqeY domain 4-epimerase keto-D-psicose glycolaldehyde GlcNAc oligosaccharide dihydroneopterin gln rhaB 5-phosphate protein] complex I: BSFG_RS12850 hydroxymethylpyrimidine deazaguanine synthase: fusion protein: