SUPPLEMENTARY DATA Table 3: Complete List of Compounds Screened with the Primary Screening Assay against Dengue Virus infection. Percentage of Inhibition of Compounds DENV Infection Lapachone, - 98.84 Mycophenolic acid 92.38 Lycorine HCl 86.86 Ivermectin 84.62 C6 Ceramide 84.06 Anisomycin 82.49 Shikonin 78.94 Cycloheximide 78.71 Chelerythrine Cl 73.36 Skimmianine 61.96 Actinomycin D 59.60 Narasin 55.89 Rapamycin 55.12 Tunicamycin B 55.01 Acivicin 54.32 Cotinine, (-)- 52.71 Cantharidin 51.87 Epigallocatechin gallate 50.92 Gitoxigenin 49.01 Kainic acid 48.87 Brefeldin A 47.12 Dicoumarol 45.99 Diacetoxyscirpenol 45.55 Austricin 45.01 Valinomycin 43.34 Thapsigargin 42.90 Strophanthidin acetate 41.96 Trimethylpsoralen, 4,5',8- 41.86 Echinomycin 41.52 Chromomycin A3 40.87 Tryptanthrin 39.03 Sanguinarine 38.73 Songorine 38.09 Condelphine 37.45 Salinomycin 35.54 Phorbol 12,13-dibutyrate 35.35 Nigericin Na 34.02 Deoxyphorbol 13- phenylacetate 20-acetate, 12- 33.74 Desoxypeganine HCl 33.07 Usnic acid, (+)- 32.59 Quisqualic acid 32.13 Gossypol 31.17 Spectinomycin sulfate 30.71 Embelin 29.70 Phorbol 12-myristate 13- acetate 29.58 Tanshinone IIA 29.01 Methoxyluteolin, 6- 28.76 Veratridine 28.47 Sevedindione 28.18 Bicuculline, (+)- 26.81 Oligomycin A 26.75 Strychnine HCl 26.70 Carminic acid 26.67 Luteolin 25.92 Manool 25.59 Homoorientin 25.09 Radicicol 25.09 Tropine 24.50 3-B-Indoleacrylic acid 24.45 Baccatin III 24.40 Citreoviridin 23.71 Bavachinin A 23.50 Ryanodine 22.87 Vulpinic acid 22.42 Quinidine HCl 22.34 Heliotrine 22.01 Saponarin 21.61 Gambogic acid 21.60 Podocarpic acid 21.36 Digitoxin 21.35 Harringtonine 20.81 Myricetin 20.49 Retinoic acid, 9-cis- 20.14 Rotenone 20.07 Cinobufagin 19.81 Taxol 19.79 Atropine-N-oxide 18.92 Myristicin 18.74 Graveoline 17.97 Menadione 17.05 Quassin 16.98 Castanospermine 16.95 Piceatannol 16.58 Protopine HCl 16.52 Ouabain (-)- 16.41 Honokiol 16.37 Caffeic Acid 16.14 Maritimein 15.82 Cyclopamine 15.72 Bergenin 15.59 CAPE 15.49 Gelsemine HCl 15.40 Wedelolactone 15.28 Isorhoifoline 15.15 Tetrahydroalstonine 14.72 Apigenin 14.68 Fumonisin B2 14.62 Hypocrellin B 13.70 Colchicine 13.27 Berberine HCl 13.17 Datiscetin 13.02 Visnagin 12.65 Tomatidine 12.44 Rottlerin 12.23 Myricitrin 12.21 Diosmetine 12.15 Vinpocetine 11.99 Rubescensin A 11.92 Deacetylcolchicine, N-formyl- 11.59 Andrographolide 11.31 Epibatidine, (±)- 11.28 Oleanolic acid 11.19 Convolvamine HCl 11.14 Wortmannin 11.06 Deguelin 11.00 Ajmaline 10.85 Harmaline HCl 10.60 Dihydroergocristine mesylate 10.50 Chrysoeriol 10.44 Narirutin 10.43 Daunorubicin HCl 10.36 Magnolol 10.34 Emodin 10.16 Lysergol 10.01 Parthenolide 10.01 Monensin Na 9.87 Ingenol 3,20-dibenzoate 9.82 Hydroxyflavone, 7- 9.78 Kavain (+/-) 9.71 Dihydrotanshinone 9.69 Cerulenin 9.54 Australine HCl 9.46 Diosmin 9.25 Grayanotoxin III 9.15 Retinoic acid (all trans) 9.09 Bulleyaconitine A 8.99 Delcorine 8.74 Prostaglandin A1 8.55 Peganole 8.48 Ebelactone B 8.39 Deltaline 8.30 Solasodine 8.25 Deoxyphorbol 13-acetate, 12- 8.02 Tamarixetine 7.95 Yangonin 7.93 Dihydroxy-4'-methoxy- chalcone, 2',6'- 7.80 Genistein 7.74 Isorhamnetine-3-O-glucoside 7.73 Chaetomellic acid A 7.73 Betulinic acid 7.63 Remerine HCl 7.62 Antibiotic A-23187 7.53 Theobromine 7.30 Chrysine 7.29 Eriocitrin 7.21 Bromocriptine mesylate 6.93 Karakoline 6.77 Ginkgolide A 6.74 Naringenin 6.47 Geranylgeranoic acid 6.30 Sinomenine 6.28 Methysticin 5.97 Bromolaudanosine, (±)-6'- 5.90 Cyclopiazonic acid 5.89 Forskolin 5.78 Galanthamine HBr 5.77 Daidzin 5.63 Chelidonine, (+)- 5.57 Troleandomycin 5.50 Asarinin, (-)- 5.37 Lapiferine 5.36 Salsolinol HBr 5.34 Lincomycin 5.24 Oxocafestol, 16- 5.16 Daidzein 5.10 Sinensetine 5.09 Mimosine, L- 5.05 Mithramycin A 5.04 Piperine 5.03 Imperialine 4.80 Conessine 4.77 Isorhamnetine-3-O-rutinoside 4.75 Diacetylkorseveriline 4.69 Marein 4.66 Tubercidin 4.64 Andrographolide, dehydro- 4.61 Pratol 4.50 Euphorbiasteroid 4.48 Dihydroxyflavone, 6,7- 4.37 Ursolic acid 4.36 Apigenin-7-O-glucoside 4.30 Papaverine HCl 4.25 Xanthotoxin 4.19 Didymin 4.16 Boldine 4.13 Puromycin 3.97 Aucubin 3.92 Homatropine HBr 3.88 Neomycin sulfate 3.75 E-64 3.59 Scopolamine N-oxide HBr, (-)- 3.51 Veratramine 3.47 Matrine 3.44 Demethylepipodophyllotoxin, 4'- 3.33 Fisetin 3.33 Isovitexin 3.18 Domoic acid 3.05 Norharmane 2.93 Retinoic acid, 13-cis- 2.76 Sclareol 2.67 Scopolomine N-butylbromide 2.43 Bufalin 2.40 Kaempferol-7- neohesperidoside 2.17 Flavokawain B 2.14 Salsolidine 2.12 Silybine 1.98 Harmalol HCl 1.88 Carnosic acid 1.86 Lapidine 1.69 Formononetin 1.59 Vincristine sulfate 1.24 Decoyinine 1.23 Huperzine A, (-)- 1.23 GERI-BP002-A 0.90 Santonin 0.84 Oxokahweol, 16- 0.81 Glycyrrhetinic acid, 18-- 0.73 Eburnamonine, (-)- 0.61 Kaempferol-3-O-glucoside 0.58 Ginkgolide B 0.56 Kaempferol 0.52 Hydrocotarnine HBr 0.45 Himbacine 0.27 Vincamine 0.12 Amygdalin 0.11 Auraptene 0.08 Tschimganidin 0.00 Dubinidine 0.00 Etoposide 0.00 Myriocin 0.00 Phloretin 0.00 Prostaglandin F2 0.00 Coumermycin A1 0.00 Isoscopoletine 0.00 Atropine sulfate 0.00 Isosakuranetin 0.00 Cycloserine, L- 0.00 Curcumin 0.00 Yohimbine HCl 0.00 Laudanosoline HBr 0.00 Tschimganine 0.00 Homobutein 0.00 Oxytetracycline, -apo- 0.00 Monocrotaline 0.00 Perillic acid 0.00 Dihydromethysticin 0.00 Nitrarine 2HCl 0.00 Ungerine nitrate 0.00 Pinocembrin 0.00 Vitexin-2"-O-rhamnoside 0.00 Fumagillin 0.00 Aconitine 0.00 Isotetrandrine 0.00 Kanamycin 0.00 Methoxyflavone, 5- 0.00 Nicotine, (-)- 0.00 Citrinin 0.00 Rhoifolin 0.00 Kahweol 0.00 Pseudopelletierin HCl 0.00 Picrotoxinin 0.00 Sitosterol, - 0.00 C2 Phytoceramide 0.00 Prostaglandin B1 0.00 E-64-D 0.00 Harmine HCl 0.00 Rosmarinic acid 0.00 Baicalein 0.00 Cevadine 0.00 Kenpaulone 0.00 Gramine 0.00 Ketopinic acid 0.00 Taxifolin (+) 0.00 Sulfuretine 0.00 E-64-C 0.00 Cyclosporin A 0.00 Fillalbin 0.00 Brucine n-oxide 0.00 Catalpol 0.00 Heteratisine 0.00 Resveratrol 0.00 Norfluorocurarine 0.00 Rhamnetine 0.00 Artesunate 0.00 Harmol HCl 0.00 Butein 0.00 Penicillamine, L- 0.00 Robinetine 0.00 Aristolochic acid A 0.00 Genistin 0.00 Nonactin 0.00 Homoeriodictyol (-) 0.00 Morin 0.00 Pilocarpine HCl 0.00 Jervine 0.00 Trichodesmine 0.00 Prostaglandin E2 0.00 Picrotin 0.00 Quercetin 0.00 Luteolin-3',7-di-o-glucoside 0.00 Vinblastine sulfate 0.00 Hyoscyamine 0.00 Capsaicin 0.00 Rauwolscine 0.00 Naringenin-7-O-glucoside 0.00 Hernandezine 0.00 Prostaglandin E1 0.00 Indirubin 0.00 Swainsonine 0.00 Berbamine 2HCl 0.00 Rifampicin 0.00 Bilobalide 0.00 E6 Berbamine 0.00 Phorbol 12,13-dibutyrate, 4-- 0.00 Arecoline HBr 0.00 Feroline 0.00 Cytochalasin B 0.00 Quinine HCl 0.00 Amentoflavone 0.00 Sterigmatocystin 0.00 Eriodictyol 0.00 Eriodictyol-7-O-glucoside 0.00 Phorbol 12-myristate 13- acetate, 4-- 0.00 Phytosphingosine 0.00 Melatonin 0.00 Gingerol 0.00 Cytochalasin D 0.00 Cytochalasin E 0.00 Eudesmine 0.00 Camptothecin 0.00 Doxorubicin HCl 0.00 Mevastatin 0.00 Plumbagin 0.00 Ellipticine 0.00 Prostaglandin J2 0.00 Hydroxycamptothecin, 10- 0.00 Hypericin 0.00 Gliotoxin 0.00 Tetrandrine 0.00 Podophylotoxin 0.00 Rhapontin 0.00 Galangine 0.00 Ecdysone 0.00 Dipterocarpol 0.00 Stachydrine HCl 0.00 Seneciphylline 0.00 Streptonigrin 0.00 Ferulic acid 0.00 Bleomycin 0.00 Ellagic acid 0.00 Methylergonovine 0.00 Naringin 0.00 Sarsasapogenin 0.00 Scopoletin 0.00 Cafestol acetate 0.00 Quercitrin 0.00 Securinine 0.00 Silymarin 0.00 Tetrahydropapaverine 0.00 Aloe-emodine 0.00 Noreleagnine 0.00 Madecassic acid 0.00 Isocorydine HCl 0.00 Abscisic acid, (±)- 0.00 Mitomycin C 0.00 Isoquercitrine 0.00 Leucomisine 0.00 Cephradine 0.00 Khellin 0.00 Betulin 0.00 Gibberellic acid, (+)- 0.00 Vitexin 0.00 Demissidine 0.00 Catharanthine base 0.00 Corydaline 0.00 Schisandrin A, R(+)- 0.00 Capreomycin sulfate 0.00 Carnitine Cl, (±)- 0.00 Chartreusin 0.00 Zearalanol, - 0.00 Limonin 0.00 Lappaconitine 0.00 Dehydrokawain, 5,6- 0.00 Rifamycin SV-NA 0.00 Senecionine 0.00 Nalidixic acid 0.00 Lupinine 0.00 Geraldol 0.00 Chlorogenic acid 0.00 Sclerotiorin 0.00 Anabasine HCl 0.00 Antimycin A1 0.00 Brassinin 0.00 Asiatic acid 0.00 Indole-3-butyric acid 0.00 Lagochiline 0.00 Ferutinin 0.00 Friedelin 0.00 Panaxadiol 0.00 Rutaecarpine 0.00 Geniposide 0.00 Tetrahydrolipstatin 0.00 Pimaricin 0.00 Muscarine Cl, (+)- 0.00 Cotininecarboxylic acid, trans- 4- 0.00 Protoveratrine B 0.00 Cryptotanshinone 0.00 Vindoline 0.00 Griseofulvin, (+)- 0.00 Dehydrocostus Lactone 0.00 Salsoline 0.00 Amphotericin B 0.00 Hordenine sulfate 0.00 Sedanolide 0.00 Noscapine, (±)- 0.00 Physostigmine 0.00 Ecdysone, - 0.00 Phorbol 0.00 Kinetin 0.00 Evodiamine 0.00 Retrorsine 0.00 Flavokawain A 0.00 Bergapten 0.00 Dihydrorobinetin 0.00 Zearalenone 0.00 Flavanomarein 0.00 Artemisinin 0.00 Cinchonidine, (-)- 0.00 Hesperidine 0.00 Anisodamine 0.00 Neohesperidin 0.00 Coumestrol 0.00 Epicatechin, (-)- 0.00 Deoxyshikonin 0.00 Minocycline 0.00 Acacetine 0.00 Sclareolide, (3aR)-(+)- 0.00 Thymoquinone 0.00 Ingenol 0.00 Phlorizine 0.00 Arbutin 0.00 Cytisine, (-)- 0.00 Patulin 0.00 Schisandrin B, S(-)- 0.00 Hesperetine 0.00 Syringetine-3-O-glucoside 0.00 Cepharanthine 0.00 Schisantherin A 0.00 Dihydrolysergol, 9,10- 0.00 Lobeline HCl 0.00 Shikimic Acid 0.00 Indole-3-carbinol 0.00 Spartein sulfate (-)- 0.00 Trigonelline HCl 0.00 Peruvoside 0.00 Lavendustin A 0.00 Osthole 0.00 Ochratoxin A 0.00 Azomycin 0.00 Solanesol 0.00 Vinorelbine base 0.00 Indole-3-acetic acid 0.00 Cafestol 0.00 Caryophyllene oxide 0.00 Palmatine Cl 0.00 Catechin hydrate, (+)- 0.00 Vanillylacetone 0.00 Corynanthine 0.00 Hypocrellin A 0.00 Hirsutine 0.00 Biochanin A 0.00 Isorhamnetine 0.00 Harmane HCl 0.00 Rutin 0.00 Solanine, - 0.00 Diindolylmethane 0.00 Pinocembrin-7-methylether 0.00 Hydrastine, D-- 0.00 Lasalocid A Na 0.00 Hydroxytropinone, 6- 0.00 Cinchonine, (+)- 0.00 D-Tubocurarine-chloride 0.00 Aphidicolin 0.00 Oxyacanthine sulfate 0.00 4-Methylumbelliferone 0.00 Wogonin 0.00 Lavendustin B 0.00 Reserpine 0.00 Isoreserpine, (-)- 0.00 Vineomycin A1 0.00 Panaxatriol 0.00 .