
Name: Dr. Raj Kumar Designation: Associate Professor (Coordinator of Centre) Centre: Pharmaceutical Sciences and Natural Products (Formerly known as Chemical and Pharmaceutical Sciences) School: Basic and Applied Sciences Central University of Punjab Bathinda-151001 Email Id: [email protected]; [email protected] Mobile:+91-9914567224/0164-2864215 Education Course Institution Year Details Ph.D. National Institute of Pharmaceutical Education and 2007 Medicinal Chemistry (With Course Research (NIPER), Mohali, India work) National Institute of Pharmaceutical Education and M.S. (Pharm.) 2002 Medicinal Chemistry Research (NIPER), Mohali, India B. Pharmacy M. D. University, Rohtak 2001 Pharmaceutical Sciences Experience Institution Designation Duration Role Teaching (Organic and Pharmaceutical Sciences and Natural Associate 28-12-2015 Medicinal) and Research Products Professor to present Pharmaceutical Sciences and Natural Teaching (Organic and Products (Formerly known as Centre for Assistant April 2011- Medicinal) and Research Chemical and Pharmaceutical Sciences), Professor 27-12-2015 Central University of Punjab, Bathinda, India Teaching and Research Indo-Soviet Friendship (ISF) College of Assistant 2009-2011 (Organic and Pharmaceutical Pharmacy, Moga, Punjab, India Professor Jan-April Chemistry) Assistant Research University of Maryland Baltimore County Research 2007-2008 (Synthesis of NCEs as (UMBC), USA Scientist Anticancer agents ) Research National Institute of Pharmaceutical Senior (Synthesis of NCEs as PDE4 Education and Research (NIPER), Mohali, Research 2003-2007 Inhibitors) in collaboration India Fellow with Ranbaxy Research Laboratories 2003 Research Dr. Reddy’s Laboratories, Hyderabad Chemist February- (Synthesis of novel anti- August infective agents) Teaching Assignments Organic Chemistry/Spectral analysis/Logics of Organic Synthesis – I and II (undergraduate level and postgraduate level). Introduction to Medicinal Chemistry (postgraduate level). Medicinal Chemistry of Anticancer Agents (postgraduate level) Research Project Handled Research(Synthesis of NCEs as PDE4 Inhibitors) in collaboration with Ranbaxy Research Laboratories Synthesis of novel anti-infective agents Synthesis of novel COX-1/COX-2 inhibitors Synthesis of novel Xanthine Oxidase inhibitors Synthesis of NCEs as Anticancer agents via EGFR/HDAC/APE-1/topoisomerase/tubulin inhibition Ongoing 1. Design, Synthesis and Biological Screening of Novel Multi-target Inhibitors of Tyrosine Kinase(s) and Topoisomerase-I - Department of Science and Technology (DST), Delhi, under the SERB Fast Track Scheme for Young Scientist-27 Lakhs 2. Design, Synthesis and Biological Screening of Novel Heterocycles as Inhibitors of Dual Tyrosine Kinase(s) and Histone Deacetylase as Potential Anticancer Agents – UGC-Major, Delhi, sanctioned money: Rs/-12,59,000 3. Design, synthesis and in vitro screening of mono-/bis- aminoquinolines as EGFR inhibitors-Research Seed Money, Central University of Punjab, Bathinda: Rs/-3,00,000 Professional Recognition /Awards/Scholarship Research award (2014-15) from Honourable Chancellor of Central University of Punjab, Bathinda on dated 28 February, 2016 (Foundation Day). Resource person at 2nd APTI at organized by Govt Polytechnic College, Patiala, Punjab, March 18-19, 2016 An Expert Member in Board of studies (Pharmacy) and Faculty of Pharmacy from 01-10-2015 – 30-09-2017 at Maharaja Ranjit Singh State Technical University, Bathinda (MRSSTU). Member, School Board of the School of Basic and Applied Sciences from 05-01-16-present at Central University of Punjab, Bathinda Member, Board of Studies (Centre for Chemical and Pharmaceutical Sciences) from November 2014- 2015-present at Central University of Punjab, Bathinda. Chairperson, Board of Studies (Centre for Chemical and Pharmaceutical Sciences) from November 2014- 2015 at Central University of Punjab, Bathinda. An Expert Member in Board of studies (Pharmacy) from December 2011- present at PTU, Jalandhar Chairperson at UGC sponsored seminar on “Green Chemistry” organized at GHG Khalsa College, Gursar Sadhar, Punjab, and February 24-25, 2012. Life Member-Chemical Research Society of India Life Member-IPGA ACS member Chairperson at APTI-16th Annual National Convention 2011 organized at I.S.F. College of Pharmacy, Moga, Punjab, India, October 7-9, 2011 Most Cited Paper 2004-2007 Award for Tetrahedron Lett.,2005,46, 1721-1724. Most Cited Paper 2005-2008 Award for Tetrahedron Lett.,2005,46, 1721-1724. Qualified National Eligibility Test for Lectureship in Chemical Sciences (CSIR-NET June 2002, conducted by Council for Scientific and Industrial Research, New Delhi, India) Qualified Graduate Aptitude Test for Engineering (GATE 2001) with 99.08 percentile (All India 30th Rank); an essential requirement for getting scholarship during M. S. Pharm. course) University Gold Medal in Bachelor of Pharmacy. Peer Recognition 1. Lead Guest Editor of Special Issue on “Signal Transduction Inhibitors as Promising Anticancer Agents” Bio Med Research International (http://www.hindawi.com/journals/bmri/si/636318/cfp/) 2. Reviewer to Molecular Biosystems (RSC) 3. Reviewer to MedChemCom (RSC) 4. Reviewer to Bioorganic and Medicinal Chemistry (BMC, Elsevier) 5. Reviewer to Bioorganic and Medicinal Chemistry Letters (BMC, Elsevier) 6. Reviewer to Food and Chemical Toxicology (FCT, Elsevier) 7. Reviewer to European Journal of Medicinal Chemistry (EJMC, Elsevier) 8. Reviewer to International Journal of Biological Macromolecules (Elsevier) 9. Reviewer to Medicinal Chemistry Research (Springer) 10. Reviewer to Mini Reviews in Medicinal Chemistry (Benthem) 11. Reviewer to Journal of Enzyme Inhibition and Medicinal Chemistry (Informa healthcare) 12. Reviewer to Letters in Drug Design & Discovery (Bentham science) 13. Reviewer to Biomarkers in Cancer (Libertas Academica) 14. Reviewer to Drug Target Insights (Libertas Academica) 15. Reviewer to Organic Chemistry Insights (Libertas Academica) 16. Associate Editor to Pharamaceutica Analytica Acta (www.omicsonline.org) 17. Reviewer to the Grant agency: Czech Republic Foundation. 18. Reviewer to the Grant agency: Department of Science and Technology, SERB Area specializations/Research Interest Design and Synthesis of novel small heterocycles as anticancer, antimalarial and xanthine oxidase inhibitors. Synthesis and methodology development of small bioactive molecules. Publications (h index = 21; Google scholar), total impact factor:120 Research Papers Year 2016 1. Synthesis and biological evaluation of new 2, 5-dimethylthiophene/furan based N-acetyl pyrazolines as selective topoisomerase II inhibitors. Darpan, G Joshi, SM Amrutkar, AT Baviskar, H Kler, S Singh, UC Banerjee, R Kumar*. RSC Adv, 2016, DOI: 10.1039/C5RA25705K. (I.F.:3.84). http://pubs.rsc.org/en/content/articlelanding/2016/ra/c5ra25705k#!divAbstract Year 2015 2. Imine/amide–imidazole conjugates derived from 5-amino-4-cyano-N1-substituted benzyl imidazole: Microwave-assisted synthesis and anticancer activity via selective topoisomerase-II-α inhibition. ANegi, JM Alex, SM Amrutkar, AT Baviskar, G Joshi, S Singh, UC Banerjee, R Kumar*. Bioorganic & medicinal chemistry, 2015, 23, 5654–5661. (I.F.:2.951). http://www.sciencedirect.com/science/article/pii/S0968089615006033. 3. Editorial Signal Transduction Inhibitors as Promising Anticancer Agent. R Kumar*, CS Dos, TS Ahluwalia, S Singh. BioMed Research International, 2015, 58, 1-10. (I.F.:2.706). http://www.hindawi.com/journals/bmri/2015/584170/ 4. Design, Microwave-mediated Synthesis and Biological Evaluation of Novel 4- Aryl(alkyl)amino-3-nitroquinoline and 2,4-Diaryl(dialkyl)amino-3-nitroquinolines as Anticancer Agents. M Chauhan, A Rana, JM Alex, A Negi, S Singh, R Kumar*. Bioorganic Chemistry, 2015, 58, 1-10. (I.F.:2.141).http://www.sciencedirect.com/science/article/pii/S0045206814001102 Year 2014 5. Synthesis and Xanthine Oxidase Inhibitory Activity of 5, 6-Dihydropyrazolo/pyrazolo [1, 5-c] quinazoline Derivatives. D Kumar, G Kaur, A Negi, S Kumar, S Singh, R Kumar*. Bioorganic Chemistry, 2014. 57, 57-64 (I.F.:2.141)http://www.sciencedirect.com/science/article/pii/S0045206814000741 6. 1‐Acetyl‐3, 5‐diaryl‐4, 5‐dihydro (1H) pyrazoles: Exhibiting Anticancer Activity through Intracellular ROS Scavenging and the Mitochondria‐Dependent Death Pathway. JM Alex, S Singh, R Kumar*. Archiv der Pharmazie, 2014, 347, 1–11 (I.F.:1.396)http://onlinelibrary.wiley.com/doi/10.1002/ardp.201400199/full 7. 2-(2-Arylphenyl) benzoxazole As a Novel Anti-Inflammatory Scaffold: Synthesis and Biological Evaluation. K Seth, SK Garg, R Kumar, P Purohit, VS Meena, R Goyal, UC Banerjee. ACS Medicinal Chemistry Letters, 2014, 5, 512–516 (I.F.:3.073; Citations: 2)http://pubs.acs.org/doi/abs/10.1021/ml400500e 8. Microwave-assisted synthesis of pyrazolo [1, 5-c] quinazolines and their derivatives. D Kumar, R Kumar*. Tetrahedron Letters, 2014, 55, 2679-2683. (I.F: 2.391; Citations: 1)http://www.sciencedirect.com/science/article/pii/S0040403914004353 Year 2013 9. Synthesis of imine-pyrazolopyrimidinones and their mechanistic interventions on anticancer activity. AT Baviskar, UC Banerjee, M Gupta, R Singh, S Kumar, MK Gupta, R Kumar*. Bioorganic & medicinal chemistry, 2013, 21, 5782-5793. (I.F.:2.951; Citations: 3)http://www.sciencedirect.com/science/article/pii/S0968089613006275 10. Selectivity control during the solid supported protic acids catalysed synthesis of 1, 2- disubstituted benzimidazoles and mechanistic insight to rationalize selectivity. D Kumar, DN Kommi,
Details
-
File Typepdf
-
Upload Time-
-
Content LanguagesEnglish
-
Upload UserAnonymous/Not logged-in
-
File Pages20 Page
-
File Size-