Authors: Ingrid Keseler Anamika Kothari Ron Caspi Carol A Fulcher An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Markus Krummenacker Amanda Mackie Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. BsubCyc: Bacillus subtilis subtilis 168 Cellular Overview Connections between pathways are omitted for legibility. Pallavi Subhraveti β-D-GlcA- (1->4)-β- D-GlcA- (1->3)-α- D-GalNAc- (1->6)-α- L-carnitine D-methionine D-GalNAc- [(2-Glc)-Gro-P] -Gro-P-ManNAc-GlcNAc-PP-undecaprenol choline sulfate n arsenite a proteinogenic glycine glycine betaine pro glu L-methionine S-oxide PP-Und a polyisoprenyl-minor wall teichoic acid (B. subtilis 168) choline D-glucopyranose myo-inositol 2-oxoglutarate D-sorbitol pro phosphate maltose amino acid a dipeptide a maltodextrin met betaine choline D-mannitol 4-aminobutanoate N-acetyl-D- glycine pro muramate betaine/ methionine wall teichoic carnitine/ choline ABC phosphotransferase phosphate dipeptide maltodextrin TmrB YhzF FtsY YobW YdhB YufS YjgA YfjD YddI EpsL YvkA AraN YbaS NarK YndK YhaL YqhP YhjO ComEC YkoI LevR YclH YhjB YcnJ RsgI TlpC ABC YuiF YfkF YqbC PbuO YtvB ResA GtcA YvcA TuaB YczM HbuT FtsW AppF PbpB YxeB YtbD GerD YfkR YfjE YvrP acid ABC TnrA YkcC TseB YozV YobI ArsB YfhA LnrJ OpuA choline/ transporter YdbK YfiU PtsG YfkC LepA YpmS CstA YxeR YerH YybF IolT YflS YitP system (PTS) GutP NdhF GabP PutP OpuE GltP SteT YfmO YabM YvoD YdfP YvgL IolF YvjA BsrG YtrD FlhB AlsT ABC MalP YbgF Mdr FliP ABC YtwI ABC YhdT YvfR MurP YwzB GlcP YxlC YoyD YdbI LytA YosE YocA YcbM YfhP SdpB SeaA YczC FliR YttA XhlA YpbE YoaT NorM RocC YvfS YmaG TetB SpmA FadF YnxB YtjA YteU YncB PsiE 02585 YotH YwcB YciB YndF YddM YocR YwbA YvzJ CcdA YubA YtrE BsrE transporter transporter choline OpuB mannitol-specific transporter transporter transporter YycB sulfate ABC YlqH β-D-GlcA- transporter (1->4)-β- [(2-Glc)-Gro-P] -Gro-P-ManNAc-GlcNAc-PP-undecaprenol arsenite glycine D-glucopyranose 4-aminobutanoate α-maltose 6'- N-acetyl-D- n myo-inositol 2-oxoglutarate D-sorbitol a proteinogenic D-methionine a polyisoprenyl-minor wall teichoic acid (B. subtilis 168) betaine 6-phosphate D-mannitol pro pro pro glu phosphate muramate 6- D-GlcA- choline amino acid a dipeptide a maltodextrin L-methionine S-oxide (1->3)-α- 1-phosphate phosphate phosphate YvaC YvgM met D-GalNAc- L-carnitine (1->6)-α- choline sulfate D-GalNAc- glycine betaine L-alanyl-γ-D- PP-Und YhcC choline glutamyl-meso-2,6- YdeJ diaminopimeloyl- Amino Acid Degradation Cofactor, Carrier, and Vitamin Biosynthesis Detoxification D-alanine superpathway of glycolysis and the Entner-Doudoroff pathway di-trans,octa-cis a UDP-N- a glycopeptide- N-acetyl-D- a (3R)-3- a (3R)-3- β arbutin 6- (R)-S- a nucleoside a [release factor]- β L-valine degradation I a -D-galactoside 4 monochlorobimane bacillithiol carbonic acid a -lactam superpathway of menaquinol-7 biosynthesis Tetrapyrrole Biosynthesis L-leucine degradation I L-histidine degradation I superoxide -undecaprenyl acetylmuramoyl- D-mannosyl-N a purine phosphate lactoylglutathione muramate 6- hydroxyoctadecanoyl- RNA hydroxyicosanoyl- L-glutamine YwbF superpathway of tetrahydrofolate biosynthesis and salvage superpathway of tetrahydrofolate biosynthesis superpathway of coenzyme A biosynthesis I (bacteria) flavin biosynthesis I (bacteria and plants) base-degraded L-cysteine biosynthesis thiamine diphosphate salvage II NAD de novo biosynthesis folate transformations III (E.