63RD ASMS CONFERENCE ON MASS SPECTROMETRY AND ALLIED TOPICS May 31 - June 4, 2015 • St. LouiS, Missouri Welcome to the 63rd ASMS Conference on Mass Spectrometry and Allied Topics. Conference program activities and exhibit booths are in America’s Center. Corporate Member hospitality suites are located in the Renaissance Grand Hotel. SPONSORS ASMS gratefully acknowledges the support TABLE OF CONTENTS of these companies. GENERAL INFORMATION ....................................... 2 HOTELS .............................................................. 5 ASMS BOARD OF DIRECTORS ............................ 6 INTEREST GROUPS AND COMMITTEES .................. 7 AWARDS.............................................................. 8 Mobile App and WiFi CONVENTION CENTER FLOOR PLANS ................ 11 CORPORATE HOSPITALITY SUITES ..................... 13 ASMS CORPORATE MEMBERS ......................... 14 Opening Reception PROGRAM ACKNOWLEDGEMENTS ....................... 19 PROGRAM OVERVIEW ........................................ 20 WORKSHOPS ..................................................... 25 Closing Event Titles in the following sections are provided by authors. The complete abstracts are available online: www.asms.org Closing Event The PDF document of proceedings submissions for orals and posters may be viewed online one day after presentation at the conference. CONFERENCE SPONSOR SUNDAY ............................................................ 32 MONDAY ORAL SESSIONS ................................. 32 CONTRIBUTORS TUESDAY ORAL SESSIONS ................................. 38 Fluid Management Systems WEDNESDAY ORAL SESSIONS ............................ 44 IDEX Health & Science THURSDAY ORAL SESSIONS .............................. 50 Microliter Analytical Supplies MONDAY POSTERS ............................................ 56 New Objective, Inc. TUESDAY POSTERS............................................ 85 Pall Laboratory PerkinElmer WEDNESDAY POSTERS ..................................... 115 Tandem Labs THURSDAY POSTERS ....................................... 143 Thermo Scientific INDEX OF AUTHORS ........................................ 171 Zef Scientific, Inc. 63ND ASMS CONFERENCE ON MASS SPECTROMETRY PAGE 1 GENERAL INFORMATION REGISTRATION is open 10:00 am - 8:00 pm on Sunday and PLENARY SESSIONS ORAL SESSIONS are 8:30 - 10:30 am and 2:30 - 4:30 pm 7:30 am - 5:00 pm on Monday through Thursday. Monday through Thursday. MONDAY, 4:45 - 5:30 PM Level 1 ATTENTION AWARD LECTURE Session A (MOA, TOA, WOA, ThOA) ....................... Hall 5 UNDERGRADUATE STUDENTS AND FIRST TIME (AT ASMS) Hall 5, level 1 Session B (MOB, TOB, WOB, ThOB) ........Room 130/132 GRADUATE STUDENTS Session C (MOC, TOC, WOC, ThOC) .......Room 123/124 4:00 - 4:45 pm, Sunday, Ballroom 220/221 Session D (MOD, TOD, WOD, ThOD) .......Room 120/127 Plan Your Strategy: What to See and Do at ASMS Award for a Distinguished Session E (MOE, TOE, WOE, ThOE) ................... Theater Contribution in Mass Spectrometry Session F (MOF, TOF, WOF, ThOF) ..................Room 106 SundAy tutoriAl SeSSion, 5:00 - 6:30 pM Level 2 Hall 5, level 1 Brian T. Chait Session G (MOG, TOG, WOG, ThOG) . Ballroom 222/224 The Rockefeller University Session H (MOH, TOH, WOH, ThOH) .. Ballroom 220/221 ORAL PRESENTATIONS are projected from ASMS computers 5:00 - 5:45 pm running Microsoft Office 2010. Speakers are required to use the Statistical Experimental Design: ASMS computers for their presentations. The Building Blocks of a Good TUESDAY, 4:45 - 5:30 PM Experiment AWARD LECTURE SPEAKERS must load presentations at least one day prior to Hall 5, level 1 their talks. The speaker room is 116, level 1 between Hall 4 Ann L. Oberg and 5. The room is open with a technician according to this Mayo Clinic schedule: Biemann Medal Sunday: 10:00 am - 8:00 pm Monday through Thursday: 7:30 am - 2:00 pm Michael J. MacCoss University of Washington POSTERS AND EXHIBIT BOOTHS are in the Poster/Exhibit Hall. 5:45 - 6:30 pm The Hall is open: Metabolite Profiling at the ‘Omic’ Sunday Reception ....................7:45 pm - 9:00 pm Scale: Untargeted Does not Mean Monday - Wednesday ..............7:30 am - 8:00 pm Unplanned Thursday ..................................7:30 am - 3:00 pm THURSDAY, 4:45 - 5:30 PM Gary Patti PLENARY LECTURE POSTER SET-UP is 7:30 am on the day scheduled. Refer Washington University, St Louis Hall 5, level 1 to the poster numbers in this final program for board The Evolution of Modern assignments. A counter for poster supplies is near the main Neurosurgery: A History of Trial and entrance to the Hall. Error, Success and Failure SundAy ConferenCe opening, 6:45 - 7:45 pM POSTER SESSIONS are 10:30 am - 2:30 pm, Monday through Hall 5, level 1 level Thursday. G. Michael Lemole, Jr. The University of Arizona College of OSTER UTHORS must be present at posters on scheduled Medicine P A Welcome days at these times. Vicki H. Wysocki 10:30 am - 1:00 pm ..........Odd-numbered posters The Ohio State University DON’T MISS 12:00 - 2:30 pm ...............Even-numbered posters ASMS Vice President for Programs Presenters who must leave a poster unattended should post a • ASMS Meeting, WedneSdAy, 4:45 - 5:30 pM return time. Presenters should wear “Poster Presenter” badges Ballroom 222/224, level 2 which are available at the poster supply counter. Enjoy a beverage while you applaud awards, hear about new initiatives, and more! Posters should not be removed before 7:30 pm on Monday, Tuesday and Wednesday. Thursday posters should be • CloSing event, thurSdAy, 6:30 - 9:00 pM removed at 2:30 pm. The Human Gut Microbiome and City Museum Healthy Growth Let’s celebrate! Your adventure LUNCH CONCESSIONS in the Poster/Exhibit hall offer a variety begins with a maze of turrets of options to dine and network while taking a break from Jeffrey L. Gordon and open “tunnels” that lead posters. Concessions are open 11:00 am - 2:00 pm, Monday Washington University, St. Louis School to views of fantastic structures through Thursday. of Medicine and sculptures. Try your skills of balance and courage, through EXHIBITORS must staff exhibit booths as follows: caves and impossible slides. End Sunday Reception ....................7:45 pm - 9:00 pm SundAy WelCoMe reCeption, 7:45 - 9:00 pM with a surprise “artist” and St. Monday - Thursday ................10:30 am - 2:30 pm Poster/Exhibit Hall. Conference name badge is required. Louis buffet. Buses will depart Exhibit Hall BC, Exhibit level from the convention center, Washington Avenue entrance. Ticket is required, $30. PAGE 2 63ND ASMS CONFERENCE ON MASS SPECTROMETRY GENERAL INFORMATION ORAL SESSIONS are 8:30 - 10:30 am and 2:30 - 4:30 pm WORKSHOPS are 5:45 - 7:00 pm on Monday, Tuesday, and Monday through Thursday. Wednesday. Light refreshments are provided in the pre-function Level 1 areas on level 1 and outside ballroom on level 2. Session A (MOA, TOA, WOA, ThOA) ....................... Hall 5 Session B (MOB, TOB, WOB, ThOB) ........Room 130/132 DINNER BreAk, 7:00 - 8:00 pM is time for a breath of fresh Session C (MOC, TOC, WOC, ThOC) .......Room 123/124 air before the opening of hospitality suites at 8:00 pm. Session D (MOD, TOD, WOD, ThOD) .......Room 120/127 Session E (MOE, TOE, WOE, ThOE) ................... Theater SPECIAL PROGRAM FOR UNDERGRADUATE STUDENTS Session F (MOF, TOF, WOF, ThOF) ..................Room 106 • Sunday, 7:30 - 9:00 pm, Poster competition, Poster/ Level 2 Exhibit Hall Session G (MOG, TOG, WOG, ThOG) . Ballroom 222/224 • Monday, 11:30 am - 1:00 pm, Meet the Experts. lunch Session H (MOH, TOH, WOH, ThOH) .. Ballroom 220/221 tables reserved for undergraduate students in the Poster/ Exhibit Hall, Free vouchers for lunch will be provided at ORAL PRESENTATIONS are projected from ASMS computers the tables. Arrive promptly at 11:30 am to obtain your running Microsoft Office 2010. Speakers are required to use the voucher. ASMS computers for their presentations. • Wednesday, 5:45 - 7:00 pm, Workshop: Getting the Most out of Undergraduate Research in Mass SPEAKERS must load presentations at least one day prior to Spectrometry, Room 230 their talks. The speaker room is 116, level 1 between Hall 4 and 5. The room is open with a technician according to this FREE WIFI ACCESS is provided in the Poster/Exhibit Hall. schedule: Computers are provided at stations throughout the convention Sunday: 10:00 am - 8:00 pm center. Monday through Thursday: 7:30 am - 2:00 pm CONFERENCE PROCEEDINGS will be published online. Visit POSTERS AND EXHIBIT BOOTHS are in the Poster/Exhibit Hall. www.asms.org after July 6 to view or download the Proceedings. The Hall is open: Submission to the Proceedings does not constitute publication Sunday Reception ....................7:45 pm - 9:00 pm and does not jeopardize the rights of authors to publish contents Monday - Wednesday ..............7:30 am - 8:00 pm of their submissions. Speaker web casting slides will be Thursday ..................................7:30 am - 3:00 pm printed to PDF and used for speakers who fail to submit. POSTER SET-UP is 7:30 am on the day scheduled. Refer WEB CASTING includes tutorial lectures, plenary lectures, to the poster numbers in this final program for board and oral sessions. Web casting will be available to conference assignments. A counter for poster supplies is near the main attendees for three months after the conference. ASMS does entrance to the Hall. not retain rights to material included in web castings. To access the presentations, go to www.asms.org and log in. After login, POSTER SESSIONS