1 Affymetrix Gene Q No. GeneDescription GOTermsBP ID Symbol value structural constituent of cytoskeleton, intermediate 1. 209351_at KRT14 keratin 14 filament, epidermis development <0.01 biological process unknown, S100 calcium binding calcium ion binding, cellular 2. 204268_at S100A2 protein A2 component unknown <0.01 regulation of progression through cell cycle, extracellular space, cytoplasm, cell proliferation, protein kinase C inhibitor activity, protein domain specific 3. 33323_r_at SFN stratifin/14-3-3σ binding <0.01 regulation of progression through cell cycle, extracellular space, cytoplasm, cell proliferation, protein kinase C inhibitor activity, protein domain specific 4. 33322_i_at SFN stratifin/14-3-3σ binding <0.01 structural constituent of cytoskeleton, intermediate 5. 201820_at KRT5 keratin 5 filament, epidermis development <0.01 structural constituent of cytoskeleton, intermediate 6. 209125_at KRT6A keratin 6A filament, ectoderm development <0.01 regulation of progression through cell cycle, extracellular space, cytoplasm, cell proliferation, protein kinase C inhibitor activity, protein domain specific 7. 209260_at SFN stratifin/14-3-3σ binding <0.01 structural constituent of cytoskeleton, intermediate 8. 213680_at KRT6B keratin 6B filament, ectoderm development <0.01 receptor activity, cytosol, integral to plasma membrane, cell surface receptor linked signal transduction, sensory perception, tumor-associated calcium visual perception, cell 9. 202286_s_at TACSTD2 signal transducer 2 proliferation, membrane <0.01 structural constituent of cytoskeleton, cytoskeleton, intermediate filament, cell-cell adherens junction, epidermis 10. 200606_at DSP desmoplakin development <0.01 lectin, galactoside- sugar binding, extracellular binding, soluble, 7 space, nucleus, apoptosis, 11. 206400_at LGALS7 (galectin 7) heterophilic cell adhesion <0.01 2 S100 calcium binding calcium ion binding, epidermis 12. 205916_at S100A7 protein A7 (psoriasin 1) development <0.01 S100 calcium binding protein A8 (calgranulin calcium ion binding, extracellular 13. 202917_s_at S100A8 A) space, inflammatory response <0.01 complement activation, lectin pathway, receptor activity, structural constituent of cytoskeleton, protein binding, protein binding, sugar binding, cytoskeleton, intermediate 14. 205900_at KRT1 keratin 1 filament, <0.01 serpin peptidase inhibitor, clade B (ovalbumin), serine-type endopeptidase 15. 204855_at SERPINB5 member 5 inhibitor activity, cell motility <0.01 calcium ion binding, calcium- dependent phospholipid binding, blood coagulation, negative 16. 203074_at ANXA8 annexin A8 regulation of coagulation <0.01 structural constituent of cytoskeleton, intermediate 17. 204734_at KRT15 keratin 15 filament, epidermis development <0.01 transporter activity, membrane fraction, integral to plasma membrane, transport, excretion, 18. 39248_at AQP3 aquaporin 3 membrane <0.01 chloride channel, calcium activated, family member 19. 217528_at CLCA2 2 <0.01 calcium ion binding, protein binding, membrane fraction, cytoskeleton, plasma membrane, intercellular junction, cell adhesion, homophilic cell 20. 206032_at DSC3 desmocollin 3 adhesion, integral to membrane <0.01 structural constituent of cytoskeleton, intermediate 21. 212236_x_at KRT17 keratin 17 filament, epidermis development <0.01 transcription factor activity, intracellular, transcription from RNA polymerase II promoter, tripartite motif-containing zinc ion binding, metal ion 22. 202504_at TRIM29 29 binding <0.01 structural constituent of cytoskeleton, protein binding, 23. 203407_at PPL periplakin cytoskeleton, keratinization <0.01 cysteine protease inhibitor 24. 204971_at CSTA cystatin A (stefin A) activity, intracellular <0.01 lymphocyte antigen 6 protein binding, membrane 25. 206276_at LY6D complex, locus D fraction, cell adhesion, membrane <0.01 3 signal transducer activity, nucleus, cytoskeleton, intermediate filament, plasma membrane, cell adhesion, signal transduction, cell-cell signaling, plakophilin 1 (ectodermal intermediate filament binding, dysplasia/skin fragility desmosome, structural constituent 26. 221854_at PKP1 syndrome) of epidermis <0.01 structural molecule activity, cytoplasm, intermediate filament, small proline-rich protein epidermis development, 27. 205064_at SPRR1B 1B (cornifin) keratinization <0.01 chloride channel, calcium activated, family member 28. 206165_s_at CLCA2 2 <0.01 calcium ion binding, protein binding, membrane fraction, cytoskeleton, plasma membrane, intercellular junction, cell adhesion, homophilic cell 29. 206033_s_at DSC3 desmocollin 3 adhesion, integral to membrane <0.01 30. 210020_x_at CALML3 calmodulin-like 3 calcium ion binding <0.01 PERP, TP53 apoptosis 31. 217744_s_at PERP effector unknown <0.01 LY6/PLAUR domain 32. 204952_at LYPD3 containing 3 unknown <0.01 transcription factor activity, nucleus, transcription, apoptosis, induction of apoptosis, Notch 33. 209863_s_at TP73L tumor protein p73-like signaling pathway <0.01 calcium ion binding, cytoskeleton, intercellular junction assembly, homophilic cell adhesion, calcium-dependent 34. 206642_at DSG1 desmoglein 1 cell-cell adhesion, <0.01 structural constituent of cytoskeleton, intermediate filament, cytoskeleton organization and biogenesis, cell proliferation, epidermis 35. 209800_at KRT16 keratin 16 development <0.01 MAP/ERK kinase kinase activity, epidermal growth factor receptor activity, negative regulation of progression through cell cycle, regulation of peptidyl-tyrosine phosphorylation, regulation of epidermal growth factor nitric-oxide synthase activity, 36. 201983_s_at EGFR receptor actin filament binding <0.01 4 actin binding, integrin binding, structural constituent of cytoskeleton, calcium ion binding, integrin-mediated signaling pathway, intermediate filament cytoskeleton 37. 204455_at DST dystonin organization and biogenesis <0.01 structural constituent of cytoskeleton, intermediate 38. 209126_x_at KRT6B keratin 6B filament, ectoderm development <0.01 structural molecule activity, small proline-rich protein epidermis development, 39. 213796_at SPRR1A 1A keratinization <0.01 nucleotide binding, GTPase activity, structural molecule activity, protein binding, GTP tubulin, alpha 1 (testis binding, microtubule, 40. 212242_at TUBA1 specific) microtubule-based movement, <0.01 calcium ion binding, protein cadherin 1, type 1, E- binding, homophilic cell 41. 201131_s_at CDH1 cadherin adhesion, integral to membrane <0.01 rhodopsin-like receptor activity, receptor activity, signal transduction, G-protein coupled G protein-coupled receptor protein signaling 42. 219936_s_at GPR87 receptor 87 pathway, <0.01 structural molecule activity, intermediate filament, epidermis 43. 213287_s_at KRT10 keratin 10 development <0.01 carbonate dehydratase activity, one-carbon compound metabolism, zinc ion binding, integral to membrane, lyase 44. 214164_x_at CA12 carbonic anhydrase XII activity, metal ion binding <0.01 chloride channel, calcium activated, family member 45. 206166_s_at CLCA2 2 unknown <0.01 extracellular region, response to pest, pathogen or parasite, defense response to bacteria, 46. 210397_at DEFB1 defensin, beta 1 innate immune response, <0.01 structural constituent of cytoskeleton, intermediate 47. 205157_s_at KRT17 keratin 17 filament, epidermis development <0.01 calcium ion binding, protein binding, cytoskeleton, desmoglein 3 (pemphigus intercellular junction, cell 48. 205595_at DSG3 vulgaris antigen) adhesion <0.01 5 transporter activity, binding, adaptor-related protein Golgi stack, coated pit, protein complex 1, gamma 1 complex assembly, intracellular 49. 215867_x_at AP1G1 subunit protein transport <0.01 carbonate dehydratase activity, one-carbon compound metabolism, zinc ion binding, 50. 203963_at CA12 carbonic anhydrase XII integral to membrane, <0.01 structural constituent of cytoskeleton, intermediate 51. 214580_x_at KRT6A keratin 6A filament, ectoderm development <0.01 structural molecule activity, intermediate filament, epidermis 52. 207023_x_at KRT10 keratin 10 development <0.01 DNA binding, RNA polymerase II transcription factor activity, Kruppel-like factor 5 nucleus, transcription, regulation 53. 209212_s_at KLF5 (intestinal) of transcription, <0.01 receptor activity, protein binding, coxsackie virus and plasma membrane, integral to 54. 203917_at CXADR adenovirus receptor plasma membrane, cell adhesion <0.01 55. 219597_s_at DUOX1 dual oxidase 1 unknown <0.01 CD24 antigen (small cell lung carcinoma cluster 4 plasma membrane, humoral 56. 209771_x_at CD24 antigen) immune response <0.01 serine-type endopeptidase inhibitor activity, cellular serpin peptidase inhibitor, component unknown, response to SERPINB1 clade B (ovalbumin), UV, regulation of proteolysis and 57. 217272_s_at 3 member 13 peptidolysis <0.01 nucleotide binding, receptor signaling protein tyrosine kinase activity, receptor activity, v-kit Hardy-Zuckerman 4 vascular endothelial growth feline sarcoma viral factor receptor activity, ATP 58. 205051_s_at KIT oncogene homolog binding, signal transduction, <0.01 S100 calcium binding 59. 218677_at S100A14 protein A14 calcium ion binding <0.01 signal transducer activity, protein binding, integral to plasma gap junction protein, membrane, connexon complex, alpha 1, 43kDa (connexin cell-cell signaling, heart 60. 201667_at GJA1 43) development, junction assembly, <0.01 transcription factor activity, nucleus, transcription, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter, defense 61. 209604_s_at GATA3 GATA binding protein