US 20190281835A1 ( 19) United States (12 ) Patent Application Publication ( 10) Pub . No. : US 2019 /0281835 A1 SAELINGER et al. (43 ) Pub . Date : Sep . 19 , 2019 ( 54 ) METHOD AND PESTICIDAL MIXTURES Publication Classification FOR CONTROLLING PENTATOMIDAE (51 ) Int. Cl. PESTS AOIN 65 /00 ( 2006 .01 ) AOIN 47 / 20 ( 2006 . 01) ( 71 ) Applicant : BASF SE , Ludwigshafen (DE ) AOIN 43 /22 ( 2006 .01 ) ( 72 ) Inventors : Daniel SAELINGER , Ludwigshafen AOIN 43 /56 ( 2006 .01 ) (DE ) ; Joachim DICKHAUT, AOIN 43 / 90 (2006 .01 ) Heidelberg (DE ) : Karsten KOERBER . (52 ) U . S . Cl. Eppelheim (DE ) ; Wolfgang VON CPC .. .. .. A01N 65 / 00 (2013 . 01 ) ; AOIN 47 /20 DEYN , Neustadt (DE ) ; Raffael ( 2013 . 01 ) ; A01N 43/ 22 ( 2013. 01 ) ; Y024 KOLLER , Zuerich (CH ) ; Arun 50 /322 ( 2018 .01 ) ; A01N 43 /90 (2013 .01 ) ; NARINE , Mannheim (DE ) ; Jean - Yves YO2A 50 /354 ( 2018 . 01 ) ; YO2A 50 / 352 WACH , Zuerich ( CH ) ; Jochen DIETZ , (2018 . 01 ) ; A01N 43 / 56 ( 2013 . 01 ) Karlsruhe (DE ) ; Diana LONDONO , Apex , NC (US ) (57 ) ABSTRACT (21 ) Appl . No .: 16 /422 , 090 The invention relates to a method for controlling pests from (22 ) Filed : May 24 , 2019 the family of Pentatonidae , comprising the step of contact ing the pests , their food supply , habitat or breeding grounds Related U . S . Application Data with a pesticidal mixture comprising as active compound I at least one component of the ginkgo tree I , selected from the (63 ) Continuation of application No . 15 /519 , 278 , filed on group consisting of bilobalide, ginkgolide A , ginkgolide B , Apr. 14 , 2017 , now Pat. No. 10 ,334 ,859 , filed as ginkgolide C , ginkgolide J and ginkgolide M , and at least application No . PCT/ EP2015 /074067 on Oct . 16 , one pesticidally active compound II and / or at least one 2015 . fungicidally active compound III , as defined in the descrip (60 ) Provisional application No . 62/ 064, 493 , filed on Oct . tion , in a synergistically effective amount. 16 , 2014 . The invention further relates to certain of these mixtures . US 2019 / 0281835 A1 Sep . 19 , 2019 METHOD AND PESTICIDAL MIXTURES [0011 ] There also exists the need for pest control agents FOR CONTROLLING PENTATOMIDAE that combine knock -down activity with prolonged control, PESTS that is , fast action with long lasting action . [0012 ] Another difficulty in relation to the use of pesti CROSS -REFERENCE TO RELATED cides is that the repeated and exclusive application of an APPLICATIONS individual pesticidal compound leads in many cases to a rapid selection of pests which have developed natural or [0001 ] This application is a continuation of U . S . applica adapted resistance against the active compound in question . tion Ser . No . 15 / 519 , 278 , filed Apr. 14 , 2017 , the entire contents of which are hereby incorporated herein by refer Therefore there is a need for pest control agents that help ence . U . S . application Ser. No. 15 /519 , 278 is a National prevent or overcome resistance . Stage application of International Application No . PCT/ [ 0013 ] It was therefore an object of the present invention EP2015 /074067 , filed Oct . 16 , 2015 , which claims the to provide pesticidal mixtures for the control of Pentatomi benefit of U . S . Provisional Application No .62 / 064 , 493, filed dae pests which solve at least one of the discussed problems Oct . 16 , 2014 , the entire contents of both of which are such as reducing the dosage rate , enhancing the spectrum of hereby incorporated herein by reference . activity or combining knock - down activity with prolonged [0002 ] The invention relates to a method for controlling control or as to resistance management. Pentatomidae pests , particularly in soybean crops, by apply [ 0014 ] It has been found that this object is in part or in ing a pesticidalmixture comprising insecticidal components whole achieved by applying the combination of active of the ginkgo tree . The invention further relates to pesticidal components of the ginkgo tree and further pesticides defined mixtures comprising insecticidal components of the ginkgo below . tree , their production and uses thereof. [0015 ] Further it has been found that mixtures of the [0003 ] Stink bugs (order of Hemiptera, family of Pentato specific active components of the ginkgo tree and further midae ) are animal pests and true bugs . They are probably insecticidal and /or fungicidal compounds show synergistic one of the most common pest problems in soybean (Stewart effect in the contest of various pests and fungi. et al. , Soybean Insects — Stink bugs , University of Tennessee [0016 ] Accordingly , in one aspect of the invention there is Institute of Agriculture, W200 09 - 0098 ) . provided a method for controlling pests from the family of [ 0004 ] Stink bugs feed on over 52 plants , including native Pentatonidae, comprising the step of contacting the pests , and ornamental trees, shrubs, vines , weeds , and many cul their food supply , habitat or breeding grounds with a pesti tivated crops such as corn and cotton , as well as numerous cidal mixture comprising as active compounds uncultivated plants, and their preferred hosts are nearly all [0017 ] 1 ) at least one compound I , which is a component wild plants . They build up on these hosts and move to of the ginkgo tree selected from the group consisting of soybeans late in the season as their preferred foods mature . bilobalide , ginkgolide A , ginkgolide B , ginkgolide C , [0005 ] Stink bugs may feed on many parts of the plant, ginkgolide J and ginkgolide M , however they typically target developing seed including the [0018 ] and pods , meaning that injury to soybean seed is the primary [0019 ] at least one pesticidally active compound II problem associated with stink bug infestations . selected from groups M and / or L consisting of [0006 ] Control of stinkbugs in soybean is often vital to [ 0020 ] II - M . 1 Acetylcholine esterase inhibitors : prevent significant economic damage . [0021 ] II - M . 1A carbamates : aldicarb , alanycarb , bendio [ 0007 ] Insecticides commonly used to control stinkbugs carb , benfuracarb, butocarboxim , butoxycarboxim , car include pyrethroids, neonicotinoids and organophosphates, baryl, carbofuran , carbosulfan , ethiofencarb , fenobucarb , though pyrethroid insecticides are usually the method of formetanate , furathiocarb , isoprocarb , methiocarb , choice for controlling stink bugs in soybean . However, there methomyl, metolcarb , oxamyl , pirimicarb , propoxur, thio are increasing problems with insecticide resistance , particu dicarb , thiofanox , trimethacarb , XMC , xylylcarb and tri larly in brown stink bug populations and particularly to azamate ; and pyrethroids . Euschistus heros can also be difficult to manage [0022 ] II - M . 1B organophosphates, for example acephate , using organophosphates or endosulfan ( Sosa -Gomez et al . , azamethiphos , azinphos - ethyl , azinphosmethyl, cadusa 2009 ) . There is therefore a need for effective ecological fos, chlorethoxyfos , chlorfenvinphos, chlormephos , chlo methods of controlling stinkbugs in soybean . rpyrifos, chlorpyrifos -methyl , coumaphos, cyanophos, [0008 ] Particularly insecticides acting on the gamma demeton - S -methyl , diazinon , dichlorvos /DDVP , dicroto aminobutyric acid (GABA ) - gated chloride channel (dis phos, dimethoate , dimethylvinphos, disulfoton , EPN , closed in e . g . WO 2005 /085216 (EP1731512 ) , WO2009 / ethion , ethoprophos, famphur, fenamiphos , fenitrothion , 002809 and WO2009 /080250 ) seem to be effective for fenthion , fosthiazate , heptenophos , imicyafos , isofen controlling stinkbugs , especially in soybean such as phos, isopropyl O - (methoxyaminothio -phosphoryl ) described in WO2012/ 104331. salicylate , isoxathion , malathion , mecarbam , methami [ 0009 ] One typical problem arising in the field of pest dophos, methidathion , mevinphos ,monocrotophos , naled , control lies in the need to reduce the dosage rates of the omethoate , oxydemeton -methyl , parathion , parathion active ingredient in order to reduce or avoid unfavorable methyl, phenthoate , phorate , phosalone , phosmet, phos environmental or toxicological effects whilst still allowing phamidon , phoxim , pirimiphos -methyl , profenofos, pro effective pest control. petamphos , prothiofos, pyraclofos, pyridaphenthion , [0010 ] Another problem encountered concerns the need to quinalphos, sulfotep , tebupirimfos, temephos , terbufos, have available pest control agents which are effective tetrachlorvinphos , thiometon , triazophos , trichlorfon and against a broad spectrum of pests . vamidothion ; US 2019 /0281835 A1 Sep . 19 , 2019 [ 0023 ] II - M . 2 .GABA - gated chloride channel antagonists : [0048 ] II - M . 13 Uncouplers of oxidative phosphorylation [ 0024 ] II - M .2A cyclodiene organochlorine compounds: via disruption of the proton gradient : chlorfenapyr, endosulfan or chlordane; and DNOC , and sulfluramid ; [0025 ] II - M . 2B fiproles: ethiprole , fipronil, flufiprole , ( 0049 ] II - M . 14 Nicotinic acetylcholine receptor channel pyrafluprole and pyriprole ; blockers : bensultap , cartap hydrochloride , thiocyclam , [0026 ] II - M . 3 Sodium channel modulators : and thiosultap sodium ; [0027 ] II- M .3A pyrethroids: acrinathrin , allethrin , d -cis [0050 ] II - M . 15 Inhibitors of the chitin biosynthesis type 1 : trans allethrin , d - trans allethrin , bifenthrin , bioallethrin , bistrifluron , chlorfluazuron , diflubenzuron , flucycloxuron , bioallethrin S - cylclopentenyl, bioresmethrin , cyclopro flufenoxuron ,