DEPARTMENT of MEDICINE 2014 Annual Report
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DEPARTMENT OF MEDICINE 2014 Annual Report DIVISIONS AND INSTITUTES The Divisions The Institutes » Allergy » Institute for Clinical Research and John Ohman, MD Health Policy Studies » Cardiology Harry Selker, MD James Udelson, MD » Molecular Cardiology Research Institute* » Clinical Decision Making, Informatics Richard Karas, MD, PhD Telemedicine» » Molecular Oncology Research Institute* John Wong, MD Philip Tsichlis, MD » Clinical Nutrition Edward Saltzman, MD »» »Endocrinology Ron Lechan, MD » Gastroenterology Joel Weinstock, MD » Geographic Medicine and Infectious Disease David Snydman, MD » Hematology/Oncology Andrew Evens, DO, MSc » Internal Medicine and Adult Primary Care Deborah Blazey-Martin, MD, MPH » Nephrology Andrew Levey, MD » Pulmonary, Critical Care and Sleep Medicine Nicholas Hill, MD » Rheumatology Timothy McAlindon, MD Photography by Martha Stewart Photography. TUFTS MEDICALDesign and CENTER production DEPARTMENT by Mark VincentOF MEDICINE Communications, — ANNUAL REPORTInc. — www.markvincent.net. 2014 TABLE OF CONTENTS The Department of Medicine Chairman’s Message 4 Departmental Organization Chart 6 Departmental Leadership 6 Clinical Activity 10 Research Activity 11 Internal Medicine Training Program 13 The Divisions 14 Allergy 16 Cardiology 18 Clinical Care Research 33 Clinical Decision Making, Informatics and Telemedicine 34 Clinical Nutrition 38 Endocrinology, Diabetes and Metabolism 41 Gastroenterology 49 Geographic Medicine and Infectious Diseases 54 Hematology/Oncology 63 Internal Medicine and Adult Primary Care 80 Geriatrics 90 William B. Schwartz Division of Nephrology 91 Pulmonary, Critical Care and Sleep Medicine 100 Rheumatology 108 The Institutes 116 Institute for Clinical Research and Health Policy Studies 118 Molecular Cardiology Research Institute (MCRI) 132 Molecular Oncology Research Institute (MORI) 140 Publications 145 CHAIRMAN’S MESSAGE 2014 saw a change in the administrative leadership of the Department of Medicine. Matthew Larkin, Administrative Director, was promoted to Vice President of Operations for the Tufts Medical Center Physicians Organization. He was replaced by Allison Ankeny, JD, MPH, whose administrative experience in both clinical and research endeavors at prestigious medical institutions will be of great value to the department. Clinical activity for the Department of Medicine showed a decrease in inpatient activity and an increase in outpatient activity for virtually all divisions, in keeping with trends throughout the country. There was gratifying growth in our two new community-based practices, i.e. in Quincy and Framingham. Deeb N. Salem, MD, FACP, FACC, FACCP— The Sheldon M. Wolff Professor and Research activity grants and contracts grew from a total of $34 million in FY 2013 to Chairman, Department of Medicine $36 million in 2014, a significant accomplishment in light of the expiration of many grants that were part of the fiscal stimulus and the generally harsher climate for government-funded research. The Institutes and Divisions have responded to the decrease in NIH-funded research by actively pursuing diversification of funding sources, which has resulted in significant growth in industry-funded projects and clinical trials, and awards from private foundation. The Division of Cardiology stood out for its cardiac transplantation, ventricular assist and hypertrophic cardiomyopathy programs, the largest such programs in New England. Its referral network for complex catheter-based coronary structural heart failure and electrophysiology procedures grew as did its trans-aortic valve program. Many members of the Division were named among Boston Magazine’s Top Doctors. John Wong, chief of the Division of Clinical Decision-Making, was named to the Institute of Medicine committee on Diagnostic Error in Health Care and served as a member of the AASLD committee on guidelines for the management of Hepatitis B. Jerome Kassirer was keynote lecturer at the European meeting of the Society for Medical Decision Making. Stephen Pauker served as a member of the End-of-Life committee of the Institute of Medicine. Edward Saltzman, chief of the Division of Nutrition, was named Academic Dean for Education at the Friedman School of Nutrition Science and Policy. The Division of Endocrinology received a grant renewal from the Friedman Foundation for Medical Research to support research and fellowship training. The Division of Gastroenterology substantially expanded its food hypersensitivity consultation center, under the directorship of John Leung. A new gastrointestinal motility service was established under the supervision of Harmony Allison. The Division of Geographic Medicine and Infectious Diseases received renewed funding of a 5 year training grant for the study of Microbial Pathogenesis. New faculty members were recruited to bring additional expertise to the study of hepatitis C and Lyme disease. Sherwood Gorbach was named Emeritus Professor of Medicine and Susan Hadley was awarded the Zucker Prize for outstanding accomplishment in teaching. Helen Boucher was named to the Infectious Disease subspecialty board of the ABIM. TUFTS MEDICAL CENTER DEPARTMENT OF MEDICINE — ANNUAL REPORT 2014 The Division of Hematology/Oncology recruited two faculty members with expertise in neuro-oncology and thoracic cancers and melanoma. A new electronic medical record was launched to integrate adult and pediatric hematology/ oncology, radiation oncology and gynecological oncology. An initiative was developed to facilitate navigation by the center’s Asian population. Other programs with philanthropic support will address cancer fatigue, holistic cancer care and sickle cell disease. Additional gifts include a sophisticated fluorescence resonance microscopy unit, a seed pledge for a multiple myeloma program, prostate research, and a survivorship program for adolescents and young adults. The Division of Internal Medicine and Adult Primary Care added 3 new primary care physicians and entered into the New England Quality Care Alliance ACO. The Division received an award from Blue Cross/Blue Shield for the detection of depression and a grant to initiate point-of-care testing for HbA1c in diabetic patients. Its new outpatient offices in Quincy and Framingham showed promising growth. The William B. Schwartz Division of Nephrology received a number of significant honors. Dr. Levey was recognized by Thomson Reuters as a highly influential researcher, Dr. Meyer received a Distinguished Faculty Award from the medical school and Dr. Perrone was the recipient of the Physician of the Year Award from the Polycystic Kidney Foundation and of the Seldin Award for clinical excellence from the National Kidney Foundation. Members of the Division of Pulmonary, Critical Care and Sleep Medicine also received notable honors. Nicholas Hill was appointed Chair of the steering committee of the NIH-sponsored Pulmonary Vascular Diseasomics project and Ioana Preston was appointed Chair of the Educational Committee of the Pulmonary Hypertension Association. In the Division of Rheumatology, Dr. Arabelovic received a medical student preceptorship grant. Other members were honored by academic promotions and appointments. Among the three Institutes, The Institute for Clinical Research and Health Policy Studies (ICRHPS) received over $6 million in new funding for 25 new research projects. Several faculty members were appointed to major national panels. Investigators in The Molecular Cardiology Research Institute (MCRI) identified a critical predictor of risk for heart disease and sudden death in diabetics. Gordon Huggins was named Principal Investigator of the Tufts Medical Center Regional Heart Failure Network and Iris Jaffee received a prestigious Established Investigator Award from the American Heart Association. Members of the Molecular Oncology Research Institute received 7 new research awards for a total of $1.23 million, delivered numerous invited lectures and were authors of 55 publications. For details of these and many other achievements, please read the full report and the list of publications. Sincerely, Deeb Salem 5 DEPARTMENTAL LEADERSHIP Deeb N. Salem, MD, FACP, FACC, FACCP Dr. Deeb Salem has had a distinguished career as an academic cardiologist. In 1987, he was appointed Professor of Medicine at Tufts University School of Medicine. He served as Chief of Cardiology at the Tufts New England Medical Center from 1987 to 1995 and was appointed the Sheldon M Wolff Professor and Chairman of the Department of Medicine at Tufts University School of Medicine and Physician-in- Chief of Tufts Medical Center in 1999. He is a Fellow of the American College of Cardiology, the American College of Physicians, and the American College of Chest Physicians. Dr. Salem was the founding President of the New England Affiliate of the American Heart Association. His academic accomplishments include over one hundred and seventy scientific publications. He is recognized as a national expert in coronary artery disease, valvular heart disease and congestive heart failure. Dr. Salem received the Distinguished Alumni Award from Boston University School of Medicine in 1998, the Distinguished Faculty Award from Tufts University School of Medicine in 1998, an American Heart Association Great Communicator Award in 1999 and an American Heart Association Distinguished Leadership Award in 2000. He received the Massachusetts Physician Health Service Distinguished Service Award in 2003. In 2007, Dr. Salem was the recipient of the American Heart Association’s