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Annual Review 2006 Faculty of Tropical Medicine, Mahidol University 1 Foreword .............................................................................................3 Editor’s Note ........................................................................................4 Executive Summary ..............................................................................5 Administrative Board ............................................................................6 Organization Chart ..............................................................................8 Special Events ......................................................................................9 Consultants .......................................................................................12 Visiting Professors 2005 .....................................................................12 Contents Faculty Board .....................................................................................12 Faculty Senate ....................................................................................12 Department of Clinical Tropical Medicine ...........................................14 Department of Helminthology ............................................................24 Department of Medical Entomology ...................................................28 Department of Microbiology and Immunology ...................................31 Department of Protozoology ..............................................................34 Department of Social and Environmental Medicine ............................37 Department of Tropical Hygiene .........................................................41 Department of Tropical Nutrition and Food Science ............................46 Department of Tropical Pathology ......................................................49 Department of Tropical Pediatrics .......................................................51 Department of Tropical Radioisotopes ................................................53 Wellcome Unit ...................................................................................55 Vaccine Trial Centre ............................................................................60 Data Management Unit ...............................................................61 Faculty of Tropical Medicine Mahidol University, Clinical Trial Section .....................................................................62 Annual Review 2006 The Bangkok School of Tropical Medicine ...........................................65 Editor: Jitra Waikagul The Hospital for Tropical Diseases .......................................................71 Compiler: Pornpimon Adams SEAMEO TROPMED Regional Centre for Tropical Medicine .................74 Editorial Staff: Warissara Chaiyabhandhu, (TROPMED/THAILAND) Sivaporn Samung, Pitchapa Vutikes Offi ce of the Dean .............................................................................80 Graphic Designer: Ronnachai Rarerng Training Programs ..............................................................................81 Layout: Phaibul Vasanakomut MOUS/Agreements ............................................................................82 English Language Consultant: Paul Adams International Linkages ........................................................................82 Produced by Research and Academic Affairs Unit, Visitors 2005......................................................................................83 Faculty of Tropical Medicine, Mahidol University, Summary of Departmental Research Projects, Publications,.................85 420/6 Ratchawithi Road, Bangkok 10400, Thailand and Presentations Tel: 66 (0) 2354-9100-19 ext. 1524, 1525 Ongoing Research Projects of the Faculty of Tropical Medicine ...........86 Fax: 66 (0) 2643-5578 in Fiscal Year 2005 E-mail: [email protected] Publications 2005 ..............................................................................93 http://www.tmpubs.tm.mahidol.ac.th TROPMED’s New Books ....................................................................102 Research Abstracts ...........................................................................103 ISSN 1686-381X -ÊÀÊÊ>ÊÞÊÕÊÌÊ Ê>ÊÞÊ>ÊÊÊ,ÊÊ>Ê` 9ÊÊÌÊ ÊiÊiÊÊÊ,ÊÊ>Ê` -9Ê/, >VÕÌÞÊvÊ iÌÃÌÀÞ ,>>Ì L`ÊëÌ> ,>ÛÌ ÊëÌ> * Þ>Ì >Ê,>` >VÕÌÞÊv *ÕLVÊi>Ì >VÕÌÞÊv `Ài½Ã 6 /À«V>Êi`Vi -Ê-i>ÀÕ / ëÌ> " , 9 Ê ,Ê>ÊÊ>ÊÊ,ÊÊ>Ê` Ê " / ,Ê>ÊÊÛÊÊÌÊ ÊÊÊÊ,ÊÊ>Ê` 1 * À>}ÕÌ>ÊëÌ> * > ÞÌ Ê,>` Annual Review 2006 2 Faculty of Tropical Medicine, Mahidol University Foreword from the Dean To commemorate His Majesty King Bhumibol Adulyadej’s 60th year of Accession to the Throne, the Faculty of Tropical Medicine is joining with Mahidol University and other government official sectors in dedicating their utmost efforts to improving the quality of life of the people, particularly those in tropical and developing countries. The Faculty of Tropical Medicine conducts three main activities: basic and clinical research in tropical medicine; provision of medical services; and postgraduate training through six international courses. The Faculty employs 98 academic staff, comprising 65 PhD and 33 Master degree graduates. The Faculty is currently affiliated with more than 20 leading institutes domestically and with more than 30 international academic institutes. The Faculty also conducts and supervises collaborative research on tropical diseases within the wider SE, South Asian regions, and world wide. I myself, as Dean, and my colleagues, aim further to strengthen the Faculty as “Asia’s Leader in Tropical Medicine” through research, education, and services. I wish to convey my sincere appreciation to all members of the Faculty, to our supporters and collaborators for their excellent work throughout the year 2005. I trust that the Faculty of Tropical Medicine Annual Review 2006 provides a comprehensive summary of the Faculty’s activities in 2005, and that any reader delving into it will find something of value and interest. Pratap Singhasivanon Dean Annual Review 2006 Faculty of Tropical Medicine, Mahidol University 3 Editor’s Note In the Year 2005 and the beginning of 2006, there was a lot of activity in the Faculty of Tropical Medicine. Particulary, the 46th Anniversary of the founding of the Faculty was symbolized by “Home- coming Day” for retired FTM members. It was the first time all five deans of the Faculty met on one day. FTM staff no doubt realize how busy we were, and that delayed publication of this issue of the Annual Review. On behalf of the team, I wish to apologize for the delay. We will definitely try for a better and faster job next year. The achievements in 2005 increased compared with the beginning of the transition period for the Dean, in 2004. From 2005, FTM granted 12 small research projects to young scientists, expecting that the published scientific papers of the Faculty in the 2007 Review will increase quantitatively and qualitatively. This was also true for our training courses, with the number of tailored short courses higher than 2004. We hope that you find these facts pleasing, and enjoy reading this Review. Assoc. Prof. Jitra Waikagul Editor Annual Review 2006 4 Faculty of Tropical Medicine, Mahidol University Executive Summary Research Current research of the Faculty of Tropical Medicine ranges from molecular research to community studies, covering more than 20 diseases including malaria, melioidosis, soil-transmitted diseases, and mosquito-borne diseases. The current research programs include clinical trials, laboratory research, field and epidemiological studies, vaccine trials, assessment of future drugs for avian influenza, and assessment of the health effects of unpredicted natural hazards and disasters. The Faculty is a pioneer research hub in conducting HIV/AIDS and dengue vaccine trials, assessment of the efficacy of antiretroviral therapies, assessments of treatments for opportunistic infections, epidemiological surveys, and analyzing social risk factors. The Faculty is well placed to conduct high quality research, having a well-established Ethics Committee, Bioequivalence Unit, an extensive Data Management Unit, a board of research consultants, and the Research and Academic Affairs Unit. We encourage collaborative studies through both local and international linkages. The Faculty is currently affiliated with more than twenty leading research institutes from all continents of the globe. As part of our research activities, we provide international postgraduate education and training in tropical medicine for scientists, physicians and others from all nations. In 2005, the Faculty published 129 international scientific papers, and 12 national or local scientific papers. There were 106 research projects, of which 49 were new, and 57 ongoing. Seventy-four papers were presented at international conferences and 11 at national conferences. The Faculty remains the leader in Asia in publishing research studies on malaria and other tropical diseases. We will continue to encourage, support, and facilitate research in tropical disease and other related global health problems. The research activities of the Faculty will continue to strive to improve the education and health of the peoples in the region. Education The Bangkok School of Tropical Medicine offers six regular international postgraduate programs-the Diploma in Tropical Medicine and Hygiene, Master of Clinical Tropical Medicine, Master of Clinical Tropical Pediatrics, Master of Science in Tropical Medicine, Doctor of Philosophy