Polyclonal Antibody to ACSL5

AP08976PU-N Acris Antibodies, Inc. Acris Antibodies GmbH

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Polyclonal Antibody to ACSL5 (C-term) - Aff - Purified Alternate names: ACS5, FACL5, LACS5, Long-chain acyl-CoA synthetase 5, Long-chain-fatty-acid--CoA ligase 5 Catalog No.: AP08976PU-N Quantity: 50 µg Background: ACSL5 is an isozyme of the long chain fatty acid coenzyme A ligase family. All isozymes of this family convert free long chain fatty acids into fatty acyl CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. ACSL5 is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid induced glioma cell growth. Three transcript variants encoding two different isoforms have been found. Uniprot ID: Q9ULC5 NCBI: NP_057318.2 GeneID: 51703 Host: Goat Immunogen: Synthetic peptide (C-RTQIDSLYEHIQD) from C-terminus of human ACSL5 Format: State: Liquid purified Ig Purification: Immunoaffinity Chromatography Buffer System: Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide Applications: Immunohistochemistry on paraffin sections: 2.5 µg/ml. Western blot: 1 - 3 µg/ml. ELISA: 1/16000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. Specificity: This antibody reacts to Acyl-CoA Synthetase Long-chain Family Member 5 (ACSL5). Species: Human. Other species not tested. Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

For research and in vitro use only. Not for diagnostic or therapeutic work. Material Safety Datasheets are available at www.acris-antibodies.com or on request. Antibody Hotline - Technical Questions - Antibody Location Service OG/20121030 Free Call: 0800-2274746 (Germany only) - www.acris-antibodies.com 1 / 2 AP08976PU-N: Polyclonal Antibody to ACSL5 (C-term) - Aff - Purified Pictures:

Small intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Antibody (1 µg/ml) staining of human spleen lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.