APEH Antibody Cat. No.: 15-005

APEH Antibody

Immunofluorescence analysis of HeLa cells using APEH antibody (15-005). Blue: DAPI for nuclear staining.

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of IMMUNOGEN: human APEH (NP_001631.3).

TESTED APPLICATIONS: IF, WB

WB: ,1:500 - 1:2000 APPLICATIONS: IF: ,1:50 - 1:200

POSITIVE CONTROL: 1) SW480

2) Jurkat

September 29, 2021 1 https://www.prosci-inc.com/apeh-antibody-15-005.html 3) Mouse liver

4) Mouse kidney

5) Mouse small intestine

6) Rat bone marrow

PREDICTED MOLECULAR Observed: 80-108kDa WEIGHT:

Properties

PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: APEH

ALTERNATE NAMES: APEH, ACPH, APH, D3F15S2, D3S48E, DNF15S2, MGC2178, OPH, AARE

GENE ID: 327

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

This encodes the acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an . This gene is located within the same region of 3 (3p21) as the aminoacylase gene, and deletions at this are also BACKGROUND: associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and .

ANTIBODIES FOR RESEARCH USE ONLY.

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