Anti-ARHGEF7 (Full Length) Polyclonal Antibody (DPABH-11524) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-ARHGEF7 (full length) polyclonal antibody (DPABH-11524) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. May function as a positive regulator of apoptosis. May function in cell migration.

Immunogen Recombinant full length protein corresponding to Human ARHGEF7 aa 1-803.Sequence: MNSAEQTVTWLITLGVLESPKKTISDPEGFLQASLKDGVVLCRLLERLLP GTIEKVYPEPRSESECLSNIREFLRGCGASLRLELLFPPSQPPQHLVTTI LLSASTFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHR IKSFDSLGSQSLHTRTSKLF

Isotype IgG

Source/Host Rabbit

Species Reactivity Mouse, Rat, Human, African green monkey

Purification Protein A purified

Conjugate Unconjugated

Applications IHC-P, WB

Format Liquid

Size 100 μg

Buffer pH: 7.3; Constituents: 50% Glycerol, 49% PBS

Preservative 0.02% Sodium Azide

Storage Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

GENE INFORMATION

Gene Name ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 [ Homo sapiens ]

Official Symbol ARHGEF7

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Synonyms ARHGEF7; Rho guanine nucleotide exchange factor (GEF) 7; rho guanine nucleotide exchange factor 7; BETA PIX; COOL1; DKFZp686C12170; DKFZp761K1021; guanine nucleotide exchange factor 7; KIAA0142; Nbla10314; P50; P50BP; P85; P85COOL1; P85SPR; PAK interacting exchange factor beta; PAK3; PIXB; rho; SH3 domain containing proline rich protein; PAK-interacting exchange factor beta; SH3 domain-containing proline-rich protein; COOL-1; BETA-PIX;

Entrez Gene ID 8874

Protein Refseq NP_001106983

UniProt ID Q14155

Chromosome Location 13q33.3

Pathway Aurora A signaling; CDC42 signaling events; Cell death signalling via NRAGE, NRIF and NADE; Class I PI3K signaling events; Disease; EGFR downregulation; G alpha (12/13) signalling events

Function Rho guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; protein binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]