EIF2AK4 Antibody Cat. No.: 14-545

EIF2AK4 Antibody

Immunohistochemistry of paraffin-embedded rat testis Immunohistochemistry of paraffin-embedded human using EIF2AK4 antibody (14-545) at dilution of 1:100 (40x breast cancer using EIF2AK4 antibody (14-545) at dilution lens). of 1:100 (40x lens).

Immunohistochemistry of paraffin-embedded mouse Immunohistochemistry of paraffin-embedded mouse testis using EIF2AK4 antibody (14-545) at dilution of 1:100 spinal cord using EIF2AK4 antibody (14-545) at dilution of (20x lens). 1:100 (40x lens).

September 27, 2021 1 https://www.prosci-inc.com/eif2ak4-antibody-14-545.html Immunohistochemistry of paraffin-embedded mouse Immunofluorescence analysis of A549 cells using EIF2AK4 brain using EIF2AK4 antibody (14-545) at dilution of 1:100 antibody (14-545). Blue: DAPI for nuclear staining. (40x lens).

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of IMMUNOGEN: human EIF2AK4 (NP_001013725.2).

TESTED APPLICATIONS: IF, IHC, WB

WB: ,1:500 - 1:2000

APPLICATIONS: IHC: ,1:50 - 1:200

IF: ,1:50 - 1:200

POSITIVE CONTROL: 1) HepG2

PREDICTED MOLECULAR Observed: 187kDa WEIGHT:

Properties

PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

September 27, 2021 2 https://www.prosci-inc.com/eif2ak4-antibody-14-545.html Additional Info

OFFICIAL SYMBOL: EIF2AK4

ALTERNATE NAMES: EIF2AK4, , GCN2 eIF2alpha , GCN2-like protein, Mgcn2, KIAA1338

GENE ID: 440275

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

This encodes a member of a family of that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding BACKGROUND: uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.

ANTIBODIES FOR RESEARCH USE ONLY.

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September 27, 2021 3 https://www.prosci-inc.com/eif2ak4-antibody-14-545.html