DOCSLIB.ORG

The National and Subnational Disease Burden of Age-Related Eye Diseases in China

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
The National and Subnational Disease Burden of Age-Related Eye Diseases in China This thesis has been submitted in fulfilment of the requirements for a postgraduate degree (e.g. PhD, MPhil, DClinPsychol) at the University of Edinburgh. Please note the following terms and conditions of use: This work is protected by copyright and other intellectual property rights, which are retained by the thesis author, unless otherwise stated. A copy can be downloaded for personal non-commercial research or study, without prior permission or charge. This thesis cannot be reproduced or quoted extensively from without first obtaining permission in writing from the author. The content must not be changed in any way or sold commercially in any format or medium without the formal permission of the author. When referring to this work, full bibliographic details including the author, title, awarding institution and date of the thesis must be given. The national and subnational disease burden of age-related eye diseases in China Peige Song, BMed, MMed, MSc Doctor of Philosophy The University of Edinburgh 2019 Declaration I, Peige Song, hereby declare that the following thesis has been composed solely by me. The work has not been previously submitted, in whole or in part, for any other degree or professional qualification. Except where the due acknowledgement is made, the work is entirely executed by myself. Date:22/02/2019 ii Abstract Background In the past decades, China has experienced one of the fastest ageing processes in the world. Alongside the demographic transition, there is a dramatic increase in age-related disability. Currently, vision loss is the leading cause of age-related disability in developing countries. Age-related eye diseases (AREDs), mainly including age-related macular degeneration (AMD), glaucoma, cataract and diabetic retinopathy, are primarily degenerative diseases in older people, whose burden is expected to increase with demographic ageing. This thesis aims to estimate the prevalence and burden of AREDs in China. Methods I searched three Chinese and three English bibliographic databases, namely China National Knowledge Infrastructure (CNKI), Wanfang, Chinese Biomedicine Literature Database (CBM-SinoMed), PubMed, Embase and Medline for studies of the prevalence of age-related macular degeneration (AMD), cataract, glaucoma, and diabetic retinopathy (DR) in China. For diseases where a single study could contribute multiple stratum-specific (e.g. age-specific and sex-specific) data points, a multilevel mixed-effects meta-regression was applied to generate the stratum-specific prevalence estimates of disease. For diseases where only study-level prevalence estimates were available, a random-effects meta-analysis was conducted to generate the pooled prevalence. By applying the estimated stratum-specific prevalence (or pooled prevalence) to the corresponding population data, available from the United Nations Population Division (UNPD), the national number of affected people was determined. By taking the geographic effects, the national number of cases was finally distributed into the six geographic regions (East China, North China, Northeast China, Northwest China, South Central China, Southwest China) in China. Results For estimating the prevalence and burden of AMD, 25 eligible studies were identified in the systematic review. The prevalence of any AMD ranged from 2.44% (95% CI: 1.85-3.22) in people aged 45-49 years to 18.98% (95% CI: 15.05-23.66) in people aged 85-89 years. iii Prevalence of early AMD ranged from 1.79% (95% CI: 1.05-3.02) to 10.05% (95% CI: 6.17- 15.97), and, in the case of late AMD, from 0.38% (95% CI: 0.16-0.97) to 3.88% (95% CI: 1.68-9.13). In late AMD, the prevalence of geographic atrophy (GA) was 0.15% (95% CI: 0.05-0.47) in people aged 45-49 years and 1.09% (95% CI: 0.35-3.36) in those aged 85-89 years, and the prevalence of neovascular AMD (NVAMD) ranged between 0.24% (95% CI: 0.11-0.50) and 2.79% (95% CI: 1.33-5.77). In people aged 45-89 years, the number of people with any AMD was 12.01 million (95% CI: 9.29-15.46) in 1990 and 26.65 million (95% CI: 20.62-34.27) in 2015. Within the same period, the number of people with early AMD increased from 9.44 million (95% CI: 7.74-11.15) to 20.91 million (95% CI: 17.16-24.68), and those with late AMD rose from 2.58 million (95% CI: 1.56-4.30) to 5.74 million (95% CI: 3.46- 9.59). In late AMD, the number of people living with GA ranged from 0.87 million (95% CI: 0.40-1.83) in 1990 to 1.93 million (95% CI: 0.89-4.08) in 2015, and NVAMD from 1.71 million (95% CI: 1.16-2.47) to 3.81 million (95% CI: 2.57-5.51). It is projected the number of people with any AMD in 2050 will be 55.19 million (95% CI: 43.04-70.30). Among different regions, the South Central owed the most AMD cases (5.50 million in 2000 and 7.52 million in 2010), whereas North-West China the least (0.66 million in 2000 and 0.95 million in 2010). For estimating the prevalence and burden of glaucoma, 30 studies met the inclusion criteria in the systematic review. In males, the prevalence of POAG ranged from 0.74% (95% CI: 0.48- 1.14) in individuals aged 45-49 years to 3.02% (95% CI: 1.92-4.73) in those aged 85-89 years. The prevalence of POAG in females was slightly lower than that in males across the whole age spectrum from 45 to 89 years, ranging from 0.54% (95% CI: 0.35-0.84) to 2.24% (95% CI: 1.41-3.53). For PACG, the prevalence increased from 0.48% (95% CI: 0.39-0.60) in males aged 45-49 years to 3.44% (95% CI: 2.66-4.45) in males aged 85-89 years. The prevalence of PACG was consistently higher in females than in males, ranging from 0.91% (95% CI: 0.74- 1.11) in females aged 45-49 years to 6.33% (95% CI: 4.98-8.02) in females aged 85-89 years. The pooled prevalence of secondary glaucoma was 0.15% (95% CI: 0.10-0.23). In people aged 45-89 years, the number of people affected by POAG increased from 2.35 million (95% CI: 1.54-3.60) in 1990 to 5.22 million (95% CI: 3.40-7.98) in 2015, PACG from 3.22 million (95% CI: 2.70-3.84) to 7.14 million (95% CI: 5.97-8.53), and secondary glaucoma from 0.34 million (95% CI: 0.23-0.53) to 0.76 million (95% CI: 0.51-1.17). In 2015, more than half (54.42%) of the glaucoma cases were PACG, followed by POAG (39.79%) and secondary glaucoma (5.79%). By 2050, the number of all glaucoma cases in China will be 25.16 million (95% CI: 18.96-33.86). %). In both 2000 and 2010, East China owed the most POAG cases (1.02 million in 2000 and 1.39 million in 2010) and PACG cases (1.24 million in 2000 and 1.68 million in iv 2010), whereas Northwest China the least (POAG: 0.19 million in 2000 and 0.27 million in 2010; PACG: 0.32 million in 2000 and 0.46 million in 2010). For estimating the prevalence and burden of cataract and cataract blindness, 55 studies met the eligibility criteria and were included in the systematic review and meta-analysis. In males, the prevalence of any cataract (including post-surgical cases) ranged from 6.71% (95% CI: 5.06- 8.83) in people aged 45-49 years to 73.01% (95% CI: 65.78-79.2) in elderly aged 85-89 years. In females, the prevalence of any cataract increased from 8.39% (95% CI: 6.36-10.98) in individuals aged 45-49 years to 77.51% (95% CI: 71.00-82.90) in those aged 85-89 years. For age-related cataract (ARC, including post-surgical cases), in males, the prevalence rates ranged from 3.23% (95% CI: 1.51-6.80) in adults aged 45-49 years to 65.78% (95% CI: 46.72- 80.82) in those aged 85-89 years. The prevalence of ARC in females was 4.72% (95% CI: 2.22-9.76) in the 45-49 years age group and 74.03% (95% CI: 56.53-86.21) in the 85–89 years age group. The pooled prevalence rate of cataract blindness (including post-surgical cases) by best corrected visual acuity (BCVA) <0.05 among middle-aged and older Chinese was 2.30% (95% CI: 1.72-3.07), and those of cataract blindness by BCVA <0.10 and cataract blindness by presenting visual acuity (PVA) <0.10 were 2.56% (95% CI: 1.94-3.38) and 4.51% (95% CI: 3.53-5.75) respectively. In people aged 45-89 years, the number of any cataract cases was 50.75 million (95% CI: 42.17-60.37) in 1990 and 111.74 million (95% CI: 92.94-132.84) in 2015, and that of ARC rose from 35.77 million (95% CI: 19.81-59.55) in 1990 to 79.04 million (95% CI: 44.14-130.85) in 2015. By 2050, it is projected that the number of people (45-89 years of age) affected by any cataract will be 240.83 million (95% CI: 206.07-277.35), and that of those with ARC will be 187.26 million (95% CI: 113.17-281.23).
Load more

Recommended publications
  • Ronshine China Holdings Limited 融信中國控股有限公司 （於開曼群島註冊成立的有限公司） （股份代號： 3301）
    香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不 負責，對其準確性或完整性亦不發表任何聲明，並明確表示，概不對因本公告 全部或任何部分內容而產生或因倚賴該等內容而引致的任何損失承擔任何責 任。 本公告並不構成在美國或任何其他司法權區提呈出售任何證券的要約或要約 購買任何證券的招攬，倘未根據任何該等司法權區的證券法例辦理登記或符 合資格前而於上述地區進行上述要約、招攬或出售即屬違法。本公告提及的證 券將不會根據證券法登記，不得在美國發售或出售，惟獲豁免遵守證券法登記 規定或屬不在證券法登記規定規限的交易除外。於美國公開發售任何證券將 會以招股章程的形式進行。該招股章程將載有關於提呈發售的公司以及其管 理及財務報表的詳盡資料。本公司無意於美國進行證券的任何公開發售。 Ronshine China Holdings Limited 融信中國控股有限公司 （於開曼群島註冊成立的有限公司） （股份代號：3301） 海外監管公告 此海外監管公告乃根據香港聯合交易所有限公司（「聯交所」）證券上市規則（「上 市規則」）第 13.10B條作出。 茲提述融信中國控股有限公司（「本公司」）日期為二零二零年七月三十日就有 關本公司票據發行的公告（「該公告」）。除文義另有所指外，本公告所用詞匯與 該公告所界定者具有相同涵義。 謹請參閱隨附日期為二零二零年七月二十九日有關票據發行之最終發售備忘 錄（「最終發售備忘錄」），最終發售備忘錄已於二零二零年八月六日刊載於新加 坡證券交易所有限公司網站。 於聯交所網站刊載最終發售備忘錄僅為促使向香港投資者發布同步資訊，並 遵守上市規則第13.10B條，概無任何其他目的。 – 1 – 最終發售備忘錄並不構成在任何司法權區公開提呈出售任何證券的招股章程、 通告、通函、小冊子或廣告，亦非邀請公眾提出認購或購買任何證券的要約， 且不旨在邀請公眾提出認購或購買任何證券的要約。 最終發售備忘錄不應被視為誘使認購或購買本公司任何證券，亦不旨在進行 該等勸誘。投資者不應根據最終發售備忘錄所載資料作出任何投資決定。 承董事會命 融信中國控股有限公司 主席 歐宗洪 香港，二零二零年八月七日 於本公告日期，歐宗洪先生、余麗娟女士、曾飛燕女士、阮友直先生、張立新先 生為執行董事；陳淑翠女士為非執行董事；及屈文洲先生、任煜男先生及阮偉 鋒先生為獨立非執行董事。 – 2 – IMPORTANT NOTICE NOT FOR DISTRIBUTION IN THE UNITED STATES You must read the following disclaimer before continuing. The following disclaimer applies to the document following this page and you are therefore advised to read this disclaimer carefully before accessing, reading or making any other use of the attached document. In accessing the attached document, you agree to be bound by the following terms and conditions, including any modifications to them from time to time, each time you receive any information from us as a result of such access. You
    [Show full text]
  • Zhou Zhongqing (2008)
    Paper Reference: Zhou Zhongqing (2008). The Ancient Tangluo Road and Huayang Township. In: Collected Papers of the Symposium on the 13 Stone Gate Treasures, Hanzhong City Museum, Hanzhong, Shaanxi, Nov 18-20, 2008, p. 132-140. The Ancient Tangluo Road and Huayang Township Zhou Zhongqing Yangxian Cultural Museum, Yangxian, Hanzhong City, Shaanxi 1. [The Tangluo Road Network]1 In ancient times in China, communication between the Guanzhong (Wei Valley), the Han River Basin and the Shu and Ba regions (present day Sichuan and Chongqing) was by ancient roads. From west to east there were altogether four of them: Chencang Road, Baoye Road, Tangluo Road and the Ziwu Road. Of these four roads, the Tangluo Road was the quickest but also the most precipitous. The complete journey was 480 Li (about 200km) and it could be covered in 4 days. The southern entrance to the Tangluo Road was called “Tang”, as it was through the entrance to the valley of the Tang River to the west of Yangxian town, abbreviated to “Tang Valley”. The northern entrance was called “Luo” and was through the West Luo Ravine to the southwest of Zhouzhi. Because the road had a north-south orientation across the Qinling these north and south valleys provided its name -- the Tangluo Road. The Tangluo Road has also been called the Luo Ravine Road in its earliest written reference in the “Records of the Three Kingdoms”. In fact, as far back as the Qin and Han periods, this ancient road had already come into being. So why did a road that came into being so early only appear in writing so late? Since humans emerged, over a long period of time, ancient peoples developed civilisation, never ceasing to discover new things.
    [Show full text]
  • CHINA VANKE CO., LTD.* 萬科企業股份有限公司 (A Joint Stock Company Incorporated in the People’S Republic of China with Limited Liability) (Stock Code: 2202)
    Hong Kong Exchanges and Clearing Limited and The Stock Exchange of Hong Kong Limited take no responsibility for the contents of this announcement, make no representation as to its accuracy or completeness and expressly disclaim any liability whatsoever for any loss howsoever arising from or in reliance upon the whole or any part of the contents of this announcement. CHINA VANKE CO., LTD.* 萬科企業股份有限公司 (A joint stock company incorporated in the People’s Republic of China with limited liability) (Stock Code: 2202) 2019 ANNUAL RESULTS ANNOUNCEMENT The board of directors (the “Board”) of China Vanke Co., Ltd.* (the “Company”) is pleased to announce the audited results of the Company and its subsidiaries for the year ended 31 December 2019. This announcement, containing the full text of the 2019 Annual Report of the Company, complies with the relevant requirements of the Rules Governing the Listing of Securities on The Stock Exchange of Hong Kong Limited in relation to information to accompany preliminary announcement of annual results. Printed version of the Company’s 2019 Annual Report will be delivered to the H-Share Holders of the Company and available for viewing on the websites of The Stock Exchange of Hong Kong Limited (www.hkexnews.hk) and of the Company (www.vanke.com) in April 2020. Both the Chinese and English versions of this results announcement are available on the websites of the Company (www.vanke.com) and The Stock Exchange of Hong Kong Limited (www.hkexnews.hk). In the event of any discrepancies in interpretations between the English version and Chinese version, the Chinese version shall prevail, except for the financial report prepared in accordance with International Financial Reporting Standards, of which the English version shall prevail.
    [Show full text]
  • 4Th International Seminar on Education, Management and Social Sciences (ISEMSS 2020)
    • 4th International Seminar on Education, Management and Social Sciences (ISEMSS 2020) Advances in Social Science, Education and Humanities Research Volume 466 Online 17 July 2020 Part 1 of 2 Editors: F. D. Mobo C.Y. Huang Y.L. Zhong ISBN: 978-1-7138-1807-6 Printed from e-media with permission by: Curran Associates, Inc. 57 Morehouse Lane Red Hook, NY 12571 Some format issues inherent in the e-media version may also appear in this print version. Copyright© (2020) by Atlantis Press All rights reserved. Copyright for individual electronic papers remains with the authors. For permission requests, please contact the publisher: Atlantis Press Amsterdam / Paris Email: [email protected] Conference Website: http://www.atlantis-press.com/php/pub.php?publication=isemss-20 Printed with permission by Curran Associates, Inc. (2021) Additional copies of this publication are available from: Curran Associates, Inc. 57 Morehouse Lane Red Hook, NY 12571 USA Phone: 845-758-0400 Fax: 845-758-2633 Email: [email protected] Web: www.proceedings.com TABLE OF CONTENTS PART 1 THE SHARING BENEFIT EVALUATION METHOD OF LARGE INSTRUMENTS AND EQUIPMENT IN COLLEGES AND UNIVERSITIES BASED ON ANALYTIC HIERARCHY PROCESS ............................................................................................................................................................. 1 Hongrui Wang, Guangtian Jia, Ran Wei RESEARCH ON THE PPP VERSUS TBLT DEBATE ...................................................................................... 5 Si Li CONSTRUCTION
    [Show full text]
  • The Lyrics of Zhou Bangyan (1056-1121): in Between Popular and Elite Cultures
    THE LYRICS OF ZHOU BANGYAN (1056-1121): IN BETWEEN POPULAR AND ELITE CULTURES by Zhou Huarao A thesis submitted in conformity with the requirements for the degree of Doctor of Philosophy Department of East Asian Studies University of Toronto © Copyright by Zhou Huarao, 2014 The Lyrics of Zhou Bangyan (1056-1121): In between Popular and Elite Cultures Huarao Zhou Doctor of Philosophy Department of East Asian Studies University of Toronto 2014 Abstract Successfully synthesizing all previous styles of the lyric, or ci, Zhou Bangyan’s (1056-1121) poems oscillate between contrasting qualities in regard to aesthetics (ya and su), generic development (zheng and bian), circulation (musicality and textuality), and literary value (assumed female voice and male voice, lyrical mode and narrative mode, and the explicit and the implicit). These qualities emerged during the evolution of the lyric genre from common songs to a specialized and elegant form of art. This evolution, promoted by the interaction of popular culture and elite tradition, paralleled the canonization of the lyric genre. Therefore, to investigate Zhou Bangyan’s lyrics, I situate them within these contrasting qualities; in doing so, I attempt to demonstrate the uniqueness and significance of Zhou Bangyan’s poems in the development and canonization of the lyric genre. This dissertation contains six chapters. Chapter One outlines the six pairs of contrasting qualities associated with popular culture and literati tradition that existed in the course of the development of the lyric genre. These contrasting qualities serve as the overall framework for discussing Zhou Bangyan’s lyrics in the following chapters. Chapter Two studies Zhou Bangyan’s life, with a focus on how biographical factors shaped his perspective about the lyric genre.
    [Show full text]
  • The Paradoxical Co-Existence of Submissiveness and Subversiveness in the Theology of Yu-Ming
    CORE Metadata, citation and similar papers at core.ac.uk Provided by University of Birmingham Research Archive, E-theses Repository THE PARADOXICAL CO-EXISTENCE OF SUBMISSIVENESS AND SUBVERSIVENESS IN THE THEOLOGY OF YU-MING JIA by CHI-YEUNG LAM A thesis submitted to The University of Birmingham for the degree of MASTER OF PHILOSOPHY Department of Theology School of Philosophy, Theology and Religion The University of Birmingham 30th July 2010 University of Birmingham Research Archive e-theses repository This unpublished thesis/dissertation is copyright of the author and/or third parties. The intellectual property rights of the author or third parties in respect of this work are as defined by The Copyright Designs and Patents Act 1988 or as modified by any successor legislation. Any use made of information contained in this thesis/dissertation must be in accordance with that legislation and must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the permission of the copyright holder. ABSTRACT This thesis aims to study Yu-ming Jia’s theology from a postcolonial perspective. Yu-ming Jia (1880-1964) is a conservative Protestant theologian who was actively engaged himself in Chinese protestant churches and theological education during the first half of the 20th century. It was seen that he constructed his theology mainly in a hierarchical context, i.e., the subjugating relationship between missionaries and Chinese Christians appearing in missionary enterprise. This study will focus on three areas of Jia’s theology: christology, ecclesiology and soteriology, which will be analysed with Homi Bhabha’s three conceptions: ambivalence, mimicry and hybridity.
    [Show full text]
  • Klint De Roodenbeke, Auguste (1816-1878) : Belgischer Diplomat Biographie 1868 Auguste T’Klint De Roodenbeke Ist Belgischer Gesandter in China
    Report Title - p. 1 of 509 Report Title t''Klint de Roodenbeke, Auguste (1816-1878) : Belgischer Diplomat Biographie 1868 Auguste t’Klint de Roodenbeke ist belgischer Gesandter in China. [KuW1] Tabaglio, Giuseppe Maria (geb. Piacenza-gest. 1714) : Dominikaner, Professor für Theologie, Università Sapienza di Roma Bibliographie : Autor 1701 Tabaglio, Giuseppe Maria ; Benedetti, Giovanni Battista. Il Disinganno contraposto da un religioso dell' Ordine de' Predicatori alla Difesa de' missionarj cinesi della Compagnia di Giesù, et ad un' altro libricciuolo giesuitico, intitulato l' Esame dell' Autorità &c. : parte seconda, conchiusione dell' opera e discoprimento degl' inganni principali. (Colonia : per il Berges, 1701). https://archive.org/details/bub_gb_ZX__WZVH6zsC. [WC] 1709 Tabaglio, Giuseppe Maria ; Fatinelli, Giovanni Jacopo. Considerazioni sù la scrittura intitolata Riflessioni sopra la causa della Cina dopò ! venuto in Europa il decreto dell'Emo di Tournon. (Roma : [s.n.], 1709). https://archive.org/details/bub_gb_YWkGIznVv70C. [WC] Tabone, Vincent (Victoria, Gozo 1913-2012 San Giljan, Malta) : Politiker, Staatspräsident von Malta Biographie 1991 Vincent Tabone besucht China. [ChiMal3] Tacchi Venturi, Pietro (San Severino Marche 1861-1956 Rom) : Jesuit, Historiker Bibliographie : Autor 1911-1913 Ricci, Matteo ; Tacchi Venturi, Pietro. Opere storiche. Ed. a cura del Comitato per le onoranze nazionali con prolegomeni, note e tav. dal P. Pietro Tacchi-Venturi. (Macerata : F. Giorgetti, 1911-1913). [KVK] Tacconi, Noè (1873-1942) : Italienischer Bischof von Kaifeng Bibliographie : erwähnt in 1999 Crotti, Amelio. Noè Tacconi (1873-1942) : il primo vescovo di Kaifeng (Cina). (Bologna : Ed. Missionaria Italiana, 1999). [WC] Tachard, Guy (Marthon, Charente 1648-1712 Chandernagor, Indien) : Jesuitenmissionar, Mathematiker Biographie Report Title - p. 2 of 509 1685 Ludwig XIV.
    [Show full text]
  • Online Supplementary Document
    Online supplementary document Song et al. The national and subnational prevalence and burden of age–related macular degeneration in China J Glob Health 2017;7:020703 Table S1. Search strategy to identify studies reporting the prevalence of age-related macular degeneration in China CNKI Access Date: 26 JUN 2016 Subject category: Medicine & Public Health Sub-database: Journal, Featured journal, Doctoral dissertation, Master dissertation, Domestic conferences, International conferences 检索表达式： (SU % '年龄相关黄斑变性' + '年龄相关性黄斑变性' + '老年黄斑变性'+ '老年性黄斑变性' + '年 龄相关黄斑病变'+ '年龄相关性黄斑病变' + '老年黄斑病变'+ '老年性黄斑病变') AND (SU % ' 发病率' + '发生率' + '患病率'+ '罹患率' + '现患率'+ '死亡率' + '病死率'+ '流行' + '负担'+ '现况调 查'+ '现况研究') 发表时间：从 1990-01-01 到 2016-06-26 Search Terms: (SU % 'nianlingxiangguanhuangbanbianxing' + 'nianlingxiangguanxinghuangbanbianxing' + 'laonianhuangbanbianxing'+ 'laonianxinghuangbanbianxing' + 'nianlingxianghguanhuangbanbingbian'+ 'nianlingxiangguanxinghuangbanbingbian' + 'laonianhuangbanbingbian'+ 'laonianxinghuangbanbingbian') AND (SU % 'fabinglv' + 'fashenglv' + 'huanbinglv'+ 'lihuanlv' + 'xianhuanlv'+ 'siwanglv' + 'bingsilv'+ 'liuxing' + 'fudan'+ 'xiankuangdiaocha'+ 'xiankuangyanjiu') Published time：From 01/01/1990 to 26/06/2016 Wanfang Access Date: 26 Jun 2016 Sub-database: Journal articles, Dissertations, Conference articles, Foreign journals, Foreign conferences 检索表达式：(主题:(年龄相关黄斑变性) + 主题:(年龄相关性黄斑变性) + 主题:(老年黄斑变 性) + 主题:(老年性黄斑变性) + 主题:(年龄相关黄斑病变) + 主题:(年龄相关性黄斑病变) + 主 题:(老年黄斑病变) + 主题:(老年性黄斑病变)) * (主题:(发病率) + 主题:(发生率) + 主题:(患病 率) +主题:(罹患率) + 主题:(现患率) + 主题:(死亡率)
    [Show full text]
  • Annual Report
    Important Notice: 1. The Board, the Supervisory Committee and the Directors, members of the Supervisory Committee and senior management of the Company warrant that in respect of the information contained in 2020 Annual Report (the “Report”, or “Annual Report”), there are no misrepresentations, misleading statements or material omission, and individually and collectively accept full responsibility for the authenticity, accuracy and completeness of the information contained in the Report. 2. The Report has been approved by the sixth meeting of the 19th session of the Board (the “Meeting”) convened on 30 March 2021. Mr. XIN Jie and Mr. TANG Shaojie, both being Non-executive Directors, did not attend the Meeting due to business engagement, and had authorised Mr. LI Qiangqiang, also a Non-executive Director, to attend the Meeting and executed voting rights on their behalf. All other Directors attended the Meeting in person. 3. The Company’s proposal on dividend distribution for the year of 2020: Based on the total share capital on the equity registration date when dividends are paid, the total amount of cash dividends proposed for distribution for 2020 will be RMB14,522,165,251.25 (inclusive of tax), accounting for 34.98% of the net profit attributable to equity shareholders of the Company for 2020, without any bonus shares or transfer of equity reserve to the share capital. Based on the Company’s total number of 11,617,732,201 shares at the end of 2020, a cash dividend of RMB12.5 (inclusive of tax) will be distributed for each 10 shares. If any circumstances, such as issuance of new shares, share repurchase or conversion of any convertible bonds into share capital before the record date for dividend distribution, results in the changes in our total number of shares on record date for dividend distribution, dividend per share shall be adjusted accordingly on the premise that the total dividends amount remains unchanged.
    [Show full text]
  • WU WENYING and the ART of SOUTHERN SONG CI POETRY By
    WU WENYING AND THE ART OF SOUTHERN SONG CI POETRY by GRACE SIEUGIT FONG B.A., University Of Toronto, 1975 M.A., University Of Toronto, 1976 A THESIS SUBMITTED IN PARTIAL FULFILMENT OF THE REQUIREMENTS FOR THE DEGREE OF DOCTOR OF PHILOSOPHY in THE FACULTY OF GRADUATE STUDIES Department Of Asian Studies We accept this thesis as conforming to the required standard THE UNIVERSITY OF BRITISH COLUMBIA October 1984 © Grace Sieugit Fong, 1984 In presenting this thesis in partial fulfilment of the requirements for an advanced degree at the University of British Columbia, I agree that the Library shall make it freely available for reference and study. I further agree that permission for extensive copying of this thesis for scholarly purposes may be granted by the Head of my Department or by his or her representatives. It is understood that copying or publication of this thesis for financial gain shall not be allowed without my written permission. Department of Asian Studies The University of British Columbia 2075 Wesbrook Place Vancouver, Canada V6T 1W5 Date: October 15, 1984 i i Abstract The thesis studies the ci_ poetry of Wu Wenying (c.1200- c.1260) in the context of Southern Song c_i_ poetics and aims to establish its significance in contemporary developments and in the tradition of ci criticism. Chapter One explores the moral and aesthetic implications of Wu's life as a "guest-poet" patronized by officials and aristocrats, and profiles two relationships in Wu's life, the loss of which generated a unique corpus of love poetry. To define the art of Southern Song c_i, Chapter Two elucidates current stylistic trends, poetics, and aesthetics of ci, examining critical concepts in two late Song treatises, the Yuefu zhimi and Ciyuan.
    [Show full text]
  • SUSTAINABLE GROWTH THROUGH COMMITMENT to EXCELLENCE Contents
    2020 INTERIM REPORT SUSTAINABLE GROWTH THROUGH COMMITMENT TO EXCELLENCE Contents Corporate Information 2 Financial Highlights 4 Business Review and Outlook 5 Management Discussion and Analysis 13 Corporate Governance and Other Information 31 Interim Condensed Consolidated Income Statement 39 Interim Condensed Consolidated Statement of Comprehensive Income 40 Interim Condensed Consolidated Balance Sheet 41 Interim Condensed Consolidated Statement of Changes in Equity 43 Interim Condensed Consolidated Statement of Cash Flows 45 Notes to the Interim Condensed Consolidated Financial Information 47 2 Ronshine China Holdings Limited 2020 Interim Report Corporate Information BOARD OF DIRECTORS AUDITOR Executive Directors PricewaterhouseCoopers Certified Public Accountants and Registered PIE Auditor Mr. Ou Zonghong 22/F, Prince’s Building (Chairman and Chief Executive Officer) Central Ms. Yu Lijuan Hong Kong Ms. Zeng Feiyan Mr. Ruan Youzhi Mr. Zhang Lixin (Chief Financial Officer) LEGAL ADVISERS As to Hong Kong law: Non-executive Director Sidley Austin Ms. Chen Shucui As to Cayman Islands law: Independent Non-executive Directors Conyers Dill & Pearman Mr. Ren Yunan As to PRC law: Mr. Qu Wenzhou Dentons Law Offices, LLP Mr. Ruan Weifeng CAYMAN ISLANDS PRINCIPAL AUDIT COMMITTEE SHARE REGISTRAR AND Mr. Qu Wenzhou (Chairman) TRANSFER OFFICE Mr. Ren Yunan Conyers Trust Company (Cayman) Limited Mr. Ruan Weifeng Cricket Square Hutchins Drive REMUNERATION COMMITTEE P.O. Box 2681, Grand Cayman, KY1-1111 Mr. Ren Yunan (Chairman) Cayman Islands Mr. Ou Zonghong Mr. Qu Wenzhou HONG KONG SHARE REGISTRAR Computershare Hong Kong Investor Services Limited NOMINATION COMMITTEE Shops 1712–1716, 17th Floor Mr. Ou Zonghong (Chairman) Hopewell Centre Mr. Qu Wenzhou 183 Queen’s Road East, Wanchai Mr.
    [Show full text]
  • Offer Document – for Convenience Purposes Only]
    [Translation of the German Offer Document – for convenience purposes only] OFFER DOCUMENT Voluntary public takeover offer for purchasing securities pursuant to Sections 29 et seqq. of the German Securities Acquisition and Takeover Act (cash offer) by AVIC International Engineering Holdings Pte. Ltd. 10 Collyer Quay # 27-00 Ocean Financial Centre Singapore (049315) and Europe Project Management Pte. Ltd. 10 Collyer Quay #27-00 Ocean Financial Centre Singapore (049315) and Europe Technology Investment Pte. Ltd. 10 Collyer Quay #27-00 Ocean Financial Centre Singapore (049315) and Europe Engineering Holdings Pte. Ltd. 10 Collyer Quay #27-00 Ocean Financial Centre Singapore (049315) to the shareholders of KHD Humboldt Wedag International AG Colonia-Allee 3, 51067 Cologne, Germany to acquire all no-par value ordinary bearer shares in KHD Humboldt Wedag International AG against a cash payment in the amount of EUR 6.45 per share Acceptance period: from 21 November 2013 to 19 December 2013, 24:00 KHD Shares: ISIN DE0006578008 (WKN 657800) Tendered KHD Shares: ISIN DE000A1YDES4 (WKN A1Y DES) Subsequently tendered KHD Shares: ISIN DE000A1YDET2 (WKN A1Y DET) Mandatory publication pursuant to Sections 34 and 14, para. 2 and 3 of the German Securities Acquisition and Takeover Act (WpÜG). No further documents form part of the Offer Document. Shareholders of KHD Humboldt Wedag International AG, in particular those who have residence, registered office or customary abode outside of the Federal Republic of Germany should pay particular attention to the statements under Sections 1.4 and 1.5 of this Offer Document. 1 [Translation of the German Offer Document – for convenience purposes only] CONTENTS CLAUSE PAGE 1.
    [Show full text]