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Table of Contents (PDF) November 14, 2017 u vol. 114 u no. 46 From the Cover 12243 Zinc and skin epidermis development E9802 Putative giant panda pheromones 12162 Handgun waiting periods and gun deaths 12202 Climate change and arctic fish biogeography 12338 Population growth and climate change policy Contents THIS WEEK IN PNAS Cover image: Pictured are epithelial 12087 In This Issue cells (green) and the zinc transporter protein ZIP10 (red) in skin from a two- day-old mouse. Bum-Ho Bin et al. found LETTERS (ONLINE ONLY) that ZIP10 is highly expressed in E9755 Better choices than optical angular momentum multiplexing epidermal hair follicles and that ZIP10- for communications mediated zinc influx is required for the David A. B. Miller activity of the epidermal development E9757 Reply to Miller: Misunderstanding and mix-up of acoustic and regulator p63. Further, deletion of the optical communications Zip10 gene in mice resulted in Chengzhi Shi and Xiang Zhang epidermal hypoplasia, indicating the E9759 Theory, simulations, and experiments show that proteins fold by significance of ZIP10 and zinc multiple pathways homeostasis to epidermal development. William A. Eaton and Peter G. Wolynes See the article by Bin et al. on pages 12243–12248. Image courtesy of Koh-ei E9761 Reply to Eaton and Wolynes: How do proteins fold? Toyoshima and Takashi Tsuji. S. Walter Englander and Leland Mayne E9763 Harmful algal blooms in the Eastern North Atlantic Ocean Paul Dees, Eileen Bresnan, Andrew C. Dale, Martin Edwards, David Johns, Beth Mouat, Callum Whyte, and Keith Davidson E9765 Reply to Dees et al.: Ocean warming promotes species-specific increases in the cellular growth rates of harmful algal blooms Christopher J. Gobler, Theresa K. Hattenrath-Lehmann, Owen M. Doherty, Andrew W. Griffith, Yoonja Kang, and R. Wayne Litaker INNER WORKINGS—An over-the-shoulder look at scientists at work 12089 Special relationship between fungi and plants may have spurred changes to ancient climate Amber Dance CORE CONCEPTS—A brief introduction to emerging topics in science 12092 Tissue resident memory cells emerging as key player in health and disease Bob Roehr COMMENTARIES 12094 Reverse chemical ecology at the service of conservation biology Walter S. Leal See companion article on page E9802 Free online through the PNAS open access option. PNAS u November 14, 2017 u vol. 114 u no. 46 u iii–vii Downloaded by guest on September 30, 2021 12097 Reducing gun violence in America 12190 Early T cell receptor signals globally modulate ligand: Jens Ludwig receptor affinities during antigen discrimination See companion article on page 12162 Rafal M. Pielak, Geoff P. O’Donoghue, Jenny J. Lin, Katherine N. Alfieri, Nicole C. Fay, Shalini T. Low-Nam, 12100 Climate warming drives large-scale changes in and Jay T. Groves ecosystem function Leif Christian Stige and Kristina Øie Kvile COMPUTER SCIENCES See companion article on page 12202 E9783 Combining disparate data sources for improved 12103 How population growth relates to climate change poverty prediction and mapping Wolfgang Lutz Neeti Pokhriyal and Damien Christophe Jacques See companion article on page 12338 EARTH, ATMOSPHERIC, AND PLANETARY SCIENCES PNAS PLUS 12144 Giant boulders and Last Interglacial storm intensity in the North Atlantic 12106 Significance Statements Alessio Rovere, Elisa Casella, Daniel L. Harris, Thomas Brief statements written by the authors about the significance of their Lorscheid, Napayalage A. K. Nandasena, Blake Dyer, papers. Michael R. Sandstrom, Paolo Stocchi, William J. D’Andrea, and Maureen E. Raymo INAUGURAL ARTICLE ENGINEERING 12111 STAT5-mediated chromatin interactions in 12150 Direct observation of impact propagation and superenhancers activate IL-2 highly inducible genes: absorption in dense colloidal monolayers Functional dissection of the Il2ra gene locus Ivo Buttinoni, Jinwoong Cha, Wei-Hsun Lin, Ste´phane Job, Peng Li, Suman Mitra, Rosanne Spolski, Jangsuk Oh, Wei Liao, Chiara Daraio, and Lucio Isa Zhonghui Tang, Fei Mo, Xingwang Li, Erin E. West, Daniel Gromer, Jian-Xin Lin, Chengyu Liu, Yijun Ruan, ENVIRONMENTAL SCIENCES and Warren J. Leonard E9793 Enhanced antibacterial activity through the controlled alignment of graphene oxide nanosheets Xinglin Lu, Xunda Feng, Jay R. Werber, Chiheng Chu, PHYSICAL SCIENCES Ines Zucker, Jae-Hong Kim, Chinedum O. Osuji, and Menachem Elimelech APPLIED MATHEMATICS 12344 White blood cell population dynamics for risk PHYSICS stratification of acute coronary syndrome Anwesha Chaudhury, Lorette Noiret, and John M. Higgins 12156 Catalysis of heat-to-work conversion in quantum machines A. Ghosh, C. L. Latune, L. Davidovich, and G. Kurizki APPLIED PHYSICAL SCIENCES E9767 Continuum limit of the vibrational properties of amorphous solids SOCIAL SCIENCES Hideyuki Mizuno, Hayato Shiba, and Atsushi Ikeda 12120 Sensing fluctuating airflow with spider silk ECONOMIC SCIENCES Jian Zhou and Ronald N. Miles 12162 Handgun waiting periods reduce gun deaths Michael Luca, Deepak Malhotra, and Christopher Poliquin BIOPHYSICS AND COMPUTATIONAL BIOLOGY See Commentary on page 12097 12126 De novo prediction of human chromosome 12338 Impact of population growth and population ethics structures: Epigenetic marking patterns on climate change mitigation policy encode genome architecture Noah Scovronick, Mark B. Budolfson, Francis Dennig, Marc Michele Di Pierro, Ryan R. Cheng, Erez Lieberman Aiden, Fleurbaey, Asher Siebert, Robert H. Socolow, Dean Spears, Peter G. Wolynes, and Jose´ N. Onuchic and Fabian Wagner See Commentary on page 12103 CHEMISTRY E9775 Interplay of hemilability and redox activity in models PSYCHOLOGICAL AND COGNITIVE SCIENCES of hydrogenase active sites 12279 Using neurostimulation to understand the impact Shengda Ding, Pokhraj Ghosh, Marcetta Y. Darensbourg, of pre-morbid individual differences on and Michael B. Hall post-lesion outcomes E9838 Parsing the roles of neck-linker docking and tethered Anna M. Woollams, Gaston Madrid, head diffusion in the stepping dynamics of kinesin and Matthew A. Lambon Ralph Zhechun Zhang, Yonathan Goldtzvik, and D. Thirumalai 12132 Assembly of silver Trigons into a buckyball-like SUSTAINABILITY SCIENCE E9783 Combining disparate data sources for improved Ag180 nanocage Zhi Wang, Hai-Feng Su, Yuan-Zhi Tan, Stan Schein, Shui-Chao poverty prediction and mapping Lin, Wei Liu, Shu-Ao Wang, Wen-Guang Wang, Chen-Ho Tung, Neeti Pokhriyal and Damien Christophe Jacques Di Sun, and Lan-Sun Zheng 12333 Supply and demand drive a critical transition to 12138 Strong texturing of lithium metal in batteries dysfunctional fisheries Feifei Shi, Allen Pei, Arturas Vailionis, Jin Xie, Bofei Liu, Jie John M. Fryxell, Ray Hilborn, Carling Bieg, Katrine Turgeon, Zhao, Yongji Gong, and Yi Cui Amanda Caskenette, and Kevin S. McCann iv u www.pnas.org Contents Downloaded by guest on September 30, 2021 12190 Early T cell receptor signals globally modulate ligand: BIOLOGICAL SCIENCES receptor affinities during antigen discrimination APPLIED BIOLOGICAL SCIENCES Rafal M. Pielak, Geoff P. O’Donoghue, Jenny J. Lin, – Katherine N. Alfieri, Nicole C. Fay, Shalini T. Low-Nam, 12166 High-throughput characterization of protein protein and Jay T. Groves interactions by reprogramming yeast mating David Younger, Stephanie Berger, David Baker, CELL BIOLOGY and Eric Klavins E9863 Sequences flanking the transmembrane segments facilitate mitochondrial localization and BIOCHEMISTRY membrane fusion by mitofusin E9802 Reverse chemical ecology: Olfactory proteins from the Xiaofang Huang, Xin Zhou, Xiaoyu Hu, Amit S. Joshi, giant panda and their interactions with putative Xiangyang Guo, Yushan Zhu, Quan Chen, William A. Prinz, pheromones and bamboo volatiles and Junjie Hu Jiao Zhu, Simona Arena, Silvia Spinelli, Dingzhen Liu, Guiquan E9873 Intercellular mRNA trafficking via membrane Zhang, Rongping Wei, Christian Cambillau, Andrea Scaloni, nanotube-like extensions in mammalian cells Guirong Wang, and Paolo Pelosi Gal Haimovich, Christopher M. Ecker, Margaret C. Dunagin, See Commentary on page 12094 Elliott Eggan, Arjun Raj, Jeffrey E. Gerst, and Robert H. Singer E9811 Molecular basis of the 14-3-3 protein-dependent E9883 Probing and manipulating intracellular membrane activation of yeast neutral trehalase Nth1 traffic by microinjection of artificial vesicles Miroslava Alblova, Aneta Smidova, Vojtech Docekal, Jan Seiichi Koike and Reinhard Jahn Vesely, Petr Herman, Veronika Obsilova, and Tomas Obsil E9893 Patterns of conserved gp120 epitope presentation E9821 Role of the nucleotidyl cyclase helical domain in on attached HIV-1 virions catalytically active dimer formation Meron Mengistu, Ai-hui Tang, James S. Foulke Jr., Thomas A. Irene Vercellino, Lenka Rezabkova, Vincent Olieric, Yevhen Blanpied, Mileidy W. Gonzalez, John L. Spouge, Robert C. Polyhach, Tobias Weinert, Richard A. Kammerer, Gunnar Gallo, George K. Lewis, and Anthony L. DeVico Jeschke, and Volodymyr M. Korkhov E9903 A vimentin binding small molecule leads to mitotic E9829 Protocadherin cis-dimer architecture and disruption in mesenchymal cancers recognition unit diversity Michael J. Bollong, Mika Pietila¨, Aaron D. Pearson, Tapasree Kerry M. Goodman, Rotem Rubinstein, Hanbin Dan, Fabiana Roy Sarkar, Insha Ahmad, Rama Soundararajan, Costas A. Bahna, Seetha Mannepalli, Go¨ran Ahlse´n, Chan Aye Thu, Lyssiotis, Sendurai A. Mani, Peter G. Schultz, Rosemary V. Sampogna, Tom Maniatis, Barry Honig, and Luke L. Lairson and Lawrence Shapiro 12196 DsbA-L prevents obesity-induced inflammation and 12172 Mechanism of RNA polymerase II stalling
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  • Rice University & Baylor College Of
    MUHAMMAD SAAD SHAMIM 1 Baylor Plaza, Suite 908B mshamim.com 956-376-6347 Houston, TX 77030 linkeDin.com/in/muhammadsaadshamim [email protected] EDUCATION Rice University & Baylor College of Medicine, Houston, TX Expected Graduation: May 2024 Medical Scientist Training Program (M.D./Ph.D.) USMLE STEP 1 251 (8/2018) Rice University, Houston, TX Graduated: May 2014 B.S. Computer Science | Biochemistry and Cell Biology Minor B.A. Computational and Applied Mathematics & Cognitive Sciences HONORS AND AWARDS Team Contribution Award, Nuclear Architecture Working Group, 2021 2021 NIH Encyclopedia of DNA Elements (ENCODE) Consortium Meeting Finalist, Hertz Fellowship, Fannie and John Hertz Foundation 2019 Fellow, Paul and Daisy Soros Fellowship for New Americans 2018 – 2020 Clinical Honors, BCM Internal Medicine Rotation 2018 Invited Speaker, Bio-IT World Conference & Expo, Cambridge Innovation Institute 2017 NASA Prize, TMCx Global Health Hackathon 2015 Reality Hacker VR App Recognition (IamCardboard VR Blog) 2015 Top Ten Must-Have Apps for Google Cardboard 2015 Top Five Unique VR Apps 2015 NCEMSF Video of the Year (bit.ly/1H8GVkZ) 2014 Rice University Outstanding Senior Award 2014 Rice University Spirit of Service Award 2014 Baker College Fellow 2014 NCEMSF Website of the Year 2014 Hamner Engineering Scholarship 2013 Baker College Outstanding Service Award 2013 Rice University VIGRE Ambassador 2012 – 2013 Memorial Hermann Volunteering Scholarship 2011 National Merit Scholar, National AP Scholar 2010 Publications Anjali Kaushal, Giriram Mohana, Julien Dorier, Isa Özdemir, Arina Omer, Pascal Cousin, Anastasiia Semenova, Michael Taschner, Oleksandr Dergai, Flavia Marzetta, Christian Iseli, Yossi Eliaz, David Weisz, Muhammad Saad Shamim, Nicolas Guex, Erez Lieberman Aiden, Maria Cristina Gambetta.
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