NACA Antibody Cat. No.: 13-442

NACA Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse, Rat

Recombinant fusion containing a sequence corresponding to amino acids 1-215 of IMMUNOGEN: human NACA (NP_001106673.1).

TESTED APPLICATIONS: IHC, IP, WB

WB: ,1:500 - 1:2000

APPLICATIONS: IHC: ,1:50 - 1:100

IP: ,1:50 - 1:100

POSITIVE CONTROL: 1) HL-60

2) SW620

3) 293T

4) U-87MG

5) HeLa

6) Mouse liver

PREDICTED MOLECULAR Observed: 37kDa WEIGHT:

September 29, 2021 1 https://www.prosci-inc.com/naca-antibody-13-442.html Properties

PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: NACA

HSD48, NAC-alpha1, skNAC, NACA, nascent polypeptide-associated complex subunit ALTERNATE NAMES: alpha, alpha-NAC, muscle-specific form, nascent-polypeptide-associated complex alpha polypeptide

GENE ID: 4666

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

This encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent that lack a motif as they emerge from the , blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to BACKGROUND: the . This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different .

ANTIBODIES FOR RESEARCH USE ONLY.

For additional information, visit ProSci's Terms & Conditions Page.

September 29, 2021 2 https://www.prosci-inc.com/naca-antibody-13-442.html