NACA Antibody Cat. No.: 13-442
NACA Antibody
Specifications
HOST SPECIES: Rabbit
SPECIES REACTIVITY: Human, Mouse, Rat
Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of IMMUNOGEN: human NACA (NP_001106673.1).
TESTED APPLICATIONS: IHC, IP, WB
WB: ,1:500 - 1:2000
APPLICATIONS: IHC: ,1:50 - 1:100
IP: ,1:50 - 1:100
POSITIVE CONTROL: 1) HL-60
2) SW620
3) 293T
4) U-87MG
5) HeLa
6) Mouse liver
PREDICTED MOLECULAR Observed: 37kDa WEIGHT:
September 29, 2021 1 https://www.prosci-inc.com/naca-antibody-13-442.html Properties
PURIFICATION: Affinity purification
CLONALITY: Polyclonal
ISOTYPE: IgG
CONJUGATE: Unconjugated
PHYSICAL STATE: Liquid
BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.
Additional Info
OFFICIAL SYMBOL: NACA
HSD48, NAC-alpha1, skNAC, NACA, nascent polypeptide-associated complex subunit ALTERNATE NAMES: alpha, alpha-NAC, muscle-specific form, nascent-polypeptide-associated complex alpha polypeptide
GENE ID: 4666
USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background and References
This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to BACKGROUND: the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes.
ANTIBODIES FOR RESEARCH USE ONLY.
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September 29, 2021 2 https://www.prosci-inc.com/naca-antibody-13-442.html