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Abstracts for Oral Presentations……………………...17
EMBO GLOBAL LECTURE COURSE AND SYMPOSIUM ON AMEBIASIS: EXPLORING THE BIOLOGY AND THE PATHOGENESIS OF Entamoeba ABSTRACT BOOk DATE: 4th- 7th March, 2012 VENUE: khajuraho, India 2 SPONSORS JAWAHARLAL NEHRU UNIVERSITY (JNU) EUROPEAN MOLECULAR BIOLOGY ORGANIZATION (EMBO) INDIAN NATIONAL SCIENCE ACADEMY (INSA) COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (CSIR) 3 4 ORGANIZING COMMITTEE Dr. ALOK BHATTACHARYA Dr. AMIR AZAM Dr. ANURADHA LOHIA Dr. JAISHREE PAUL Dr. S.GOURINATH Dr. SUDHA BHATTACHARYA Dr. SWATI TIWARI Dr. VINEET AHUJA SCIENTIFIC PROGRAM COMMITTEE Dr. SUDHA BHATTACHARYA Dr. ANURADHA LOHIA Dr. DAVID MIRELMAN Dr. NANCY GUILLEN Dr. TOMOYASHI NOZAKI Dr. UPINDER SINGH Dr. WILLIAM PETRI Jr. 5 6 contents Programme schedule…………………………………..9 Abstracts for oral presentations……………………...17 Abstracts for poster presentations……………………53 List of participants……………………………………115 Index……………………………………………………123 7 8 PROGRAM SCHEDULE Day 1, March 4th, 2012 13:00 Arrival Khajuraho 16:00-16:20 Inauguration of the Conference Alok Bhattacharya, India 16:20-17:00 David Mirelman, Weizmann Institute, Israel Modulation of gene expression in Entamoeba histolytica: a short review of successes and failures. 17:00-17:20 Coffee Break 17:20-19:20 Session I - Genomics and transcriptomics Chairperson: Graham Clark, UK 17:20-17:50 Neil Hall, Institute of Integrative Biology, University of Liverpool, UK Genomic Diversity of the human gut parasite Entamoeba histolytica 17:50-18:20 Chung-Chau Hon, Pasteur Institute, Paris Characterization of a complex Repertoire of rare splicing isoforms, Endogenous Small RNAs and natural Antisense RNAs in Entamoeba histolytica using High-throughput sequencing. 18:20-18:50 Sudha Bhattacharya, School of Environmental Sciences, JNU, India Novel features of ribosomal DNA transcription and SINE mobilization in Entamoeba histolytica: an overview. -
Annual Report 2015-16
ANNUAL REPORT 2015-16 TABLE OF CONTENTS VICE CHANCELLOR'S PROGRESS REPORT ...................................................................................................................... 2 UNIVERSITY LEADERSHIP ................................................................................................................................................... 6 ABOUT THE UNIVERSITY ................................................................................................................................................. 11 MISSION AND OBJECTIVES, VISION AND PURPOSE, VALUES AND PRINCIPLES ............................................. 12 ABOUT SCHOOLS, DEPARTMENTS AND RESEARCH CENTERS ............................................................................. 14 UGC EXPERT COMMITTEE REPORT .............................................................................................................................. 22 RESEARCH AT SHIV NADAR UNIVERSITY ................................................................................................................... 23 ACTIVE EXTERNAL RESEARCH GRANTS ..................................................................................................................... 25 APPROVED AND RECOMMENDED FOR FUNDING PROJECTS ............................................................................... 32 UNDERGRADUATE RESEARCH AND OUR CONFERENCE ........................................................................................ 36 GLOBAL COLLABORATIONS ........................................................................................................................................... -
Transcriptomic Analysis of Entamoeba Histolytica Reveals Domain-Specific Sense Strand Expression of LINE-Encoded Orfs with Massive Antisense Expression of RT Domain
Plasmid 114 (2021) 102560 Contents lists available at ScienceDirect Plasmid journal homepage: www.elsevier.com/locate/yplas Transcriptomic analysis of Entamoeba histolytica reveals domain-specific sense strand expression of LINE-encoded ORFs with massive antisense expression of RT domain Devinder Kaur a,1,2, Mridula Agrahari a,1, Shashi Shekhar Singh a,3, Prabhat Kumar Mandal b, Alok Bhattacharya c, Sudha Bhattacharya a,4,* a School of Environmental Sciences, Jawaharlal Nehru University, India b Department of Biotechnology, IIT Roorkee, India c Ashoka University, Sonepat, India ARTICLE INFO ABSTRACT Keywords: LINEs are retrotransposable elements found in diverse organisms. Their activity is kept in check by several EhLINE1 mechanisms, including transcriptional silencing. Here we have analyzed the transcription status of LINE1 copies Antisense RNA in the early-branching parasitic protist Entamoeba histolytica. Full-length EhLINE1 encodes ORF1, and ORF2 with LINE transcriptome reverse transcriptase (RT) and endonuclease (EN) domains. RNA-Seq analysis of EhLINE1 copies (both truncated Truncated transcripts and full-length) showed unique features. Firstly, although 20/41 transcribed copies were full-length, we failed to RNA-Seq E. histolytica detect any full-length transcripts. Rather, sense-strand transcripts mapped to the functional domains- ORF1, RT Internal deletion and EN. Secondly, there was strong antisense transcription specificallyfrom RT domain. No antisense transcripts Read-through transcription were seen from ORF1. Antisense RT transcripts did not encode known functional peptides. They could possibly be involved in attenuating translation of RT domain, as we failed to detect ORF2p, whereas ORF1p was detectable. Lack of full-length transcripts and strong antisense RT expression may serve to limit EhLINE1 retrotransposition. -
Multiple Change-Point Detection for Piecewise Stationary Categorical Time Series
MULTIPLE CHANGE-POINT DETECTION FOR PIECEWISE STATIONARY CATEGORICAL TIME SERIES by Cong Ye B.S., Statistics, Wuhan University, 2008 M.A., Applied Statistics, University of Pittsburgh, 2010 Submitted to the Graduate Faculty of the Kenneth P. Dietrich School of Arts and Sciences in partial fulfillment of the requirements for the degree of Doctor of Philosophy University of Pittsburgh 2015 UNIVERSITY OF PITTSBURGH KENNETH P. DIETRICHDIETRICH SCHOOL OF ARTS AND SCIENCES This dissertation was presented by Cong Ye It was defended on November 18th 2015 and approved by David S. Stoffer, Ph.D., Department of Statistics,Professor Yu Cheng, Ph.D., Department of Statistics, Associate Professor Sungkyu Jung, Ph.D., Department of Statistics, Assistant Professor Ching-Chung Li, Ph.D., Department of Electrical and Computer Engineering, Professor Dissertation Director: David S. Stoffer, Ph.D., Department of Statistics,Professor ii Copyright c by Cong Ye 2015 iii MULTIPLE CHANGE-POINT DETECTION FOR PIECEWISE STATIONARY CATEGORICAL TIME SERIES Cong Ye, PhD University of Pittsburgh, 2015 In this dissertation, we propose a fast yet consistent method for segmenting a piecewise stationary categorical-valued time series, with a finite unknown number of change-points in its autocovariance structure. To avoid loss of information, instead of arbitrarily assign- ing numerical numbers in analysis of the original time series, we focus on the multinomial process, which is derived by denoting each category of the original series as a unit vector. The corresponding multinomial process is then modeled by a nonparametric multivariate locally stationary wavelet process, where the piecewise constant autocovariance structure for any given variate is completely described by the wavelet periodograms for that variate at multiple scales and locations. -
Sudha Bhattacharya Ph. D., F.A.Sc., F.N.A.Sc., F.N.A. Professor School of Environmental Sciences Jawaharlal Nehru University New Delhi-110 067
Sudha Bhattacharya Ph. D., F.A.Sc., F.N.A.Sc., F.N.A. Professor School of Environmental Sciences Jawaharlal Nehru University New Delhi-110 067 [email protected], [email protected] Educational and Professional Record: Institution Degree/Post Year Field of study/Research University of Delhi, Botany (main), B. Sc.(Hons.) 1971 Delhi Zoology, Chemistry Indian Agricultural Research Biochemistry (main), Institute, M. Sc. 1973 Genetics, Microbiology New Delhi Indian Agricultural Research Institute, Ph. D. 1977 Biochemistry New Delhi Stanford University, Post-doctoral 1977-1979 Bacteriophage genetics USA Boston Biomedical Research Institute, Staff-fellow 1979-1981 Bacterial DNA Replication USA All India Institute ofMedical Genetic engineering in Sciences, Research Officer 1981 -1982 Mycobacteria New Delhi Tata Research Development of DNA Development & Design Scientist 1982-1985 probes for tuberculosis and Centre, other diseases Pune National Institutes of World Bank Repetitive DNA Health, 1985-1986 Fellow in Entamoeba histolytica U.S.A. Jawaharlal Nehru University, Assistant Molecular biology of 1986-1995 New Delhi Professor amoebiasis Jawaharlal Nehru University, Associate Molecular biology of 1995-2003 New Delhi Professor amoebiasis Jawaharlal Nehru University, 2003- Molecular biology of Professor New Delhi present amoebiasis Awards: National Science Talent Search Scholarship (1968) Merit position in Central Board of Secondary Education (1968) Robert Mc Namara Fellow of World Bank (1985) Rockefeller Biotechnology Career Development Award (1987) Fogarty International Research Collaboration Award (1996) Fogarty International Research Collaboration Award (2001) Honours: Member of Guha Research Conference (1993) Fellow of the Indian Academy of Sciences, Bangalore (2001) Fellow of the National Academy of Sciences, Allahabad (2008) Fellow of the Indian National Science Academy (2014) List of Publications: 1. -
Annual Report
1 COMPILED BY Geetha, K. Geetha Sugumaran Ravi Kumar, C. S. Roopashri, M. S. Savitha Nair Srimathi, M. Thirumalai, N. Vanitha, M. PUBLISHED BY Venkatarathnam, N. Executive Secretary, Indian Academy of Sciences, EDITED BY C.V. Raman Avenue, Anuradha, R. Post Box No. 8005, Nagesh, K. Sadashivanagar P.O., Sushila Rajagopal Bengaluru 560 080 Usha Susan Philip Phone (EPABX): 91-80-2266-1200 Fax: 91-80-2361-6094 PHOTOS Email: off [email protected] The Academy Archives Website: www.ias.ac.in GRAPHICS & DESIGN Subhankar Biswas Copyright Indian Academy of Sciences 2 Contents Foreword 4 1. Introduction 5 2. Vision, Mission, Objectives & Functions 6 3. Progress Report 9 4. Council 12 5. Fellowship 14 6. Associates 21 7. Publications 29 8. Scientific Meetings Mid-Year Meeting 2017 70 Annual Meeting 2017 80 Discussion Meetings 108 9. Repository of Scientific Publications 122 10. Chair Professorships Raman Chair 123 Janaki Ammal Chair 123 Jubilee Chair 124 Academy–Springer Nature Chair 126 11. Science Education Programmes 128 12. ‘Women in Science’ Panel Programmes 148 13. Public Lectures 154 14. National Science Day 2017 163 15. Hindi Workshop 164 16. Vigilance Awareness Week 164 17. Academy Finances 165 18. Acknowledgements 167 19. Tables 168 20. Personnel 171 21. Statement of Finances 175 3 Foreword The scientific programmes of the Academy in the year 2017–18 had some new initiatives. The Academy started two online-only journals – Dialogue: Science, Scientists, and Society and IASc Conference Series. The former is a scholarly forum for scientists and interested stakeholders to discuss and debate issues pertaining to scientists and society. -
Patrika-March 2016.Pmd
No. 63 March 2016 Newsletter of the Indian Academy of Sciences EIGHTY-FIRST ANNUAL MEETING, PUNE 6–8 NOVEMBER 2015 The 81st Annual Meeting of the Indian Academy of Sciences was held at IISER–Pune. The meeting was hosted by IISER – Pune in association with CSIR–NCL Inside... and NCCS, during 6 to 8 November 2015. The three-day meeting began with the Presidential Address, followed by 1. Eighty-First Annual Meeting, Pune ........................ 1 two mini-symposia – one on “Light and Matter” and the other on “General Relativity”, two public lectures, two 2. Council ................................................................... 7 special lectures, as well as lectures on various topics by 3. Twenty-Seventh Mid-Year Meeting ....................... 8 Fellows and Associates of the Academy. This meeting 4. Elections 2016 ....................................................... 9 was attended by 130 Fellows and Associates of the 5. Special Issues of Journals ................................... 11 Academy and by 40 teachers. 6. Promotion of Academy Journals .......................... 13 On 5th November, members of the Science Education 7. Discussion Meetings ............................................ 14 Panel met with the invited teachers in an interactive session. 8. Raman Professor................................................. 16 This meeting was also attended by the Fellows of the Academy who were present on that day at the meeting 9. Jubilee Professor ................................................. 16 venue. 10. Academy Public Lectures .................................... 17 In his Presidential Address, Dipankar Chatterji (IISc, 11. 'Women in Science' Panel Programmes ............. 18 Bengaluru) spoke on the social behaviour of bacteria. It 12. National Science Day 2016 ................................ 19 is known that bacteria exhibit several responses under 13. Repository of Scientific Publications of stress which are intimately related to community behaviour; Academy Fellows ................................................ 19 14. -
Title Ultra-Structural Analysis and Morphological Changes
bioRxiv preprint doi: https://doi.org/10.1101/2020.06.03.131367; this version posted June 12, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. 1 Title 2 Ultra-structural analysis and morphological changes during the differentiation of 3 trophozoite to cyst in Entamoeba invadens 1∗ 4 Nishant Singh †, Sarah Naiyer†2 and Sudha Bhattacharya3 5 School of Environmental Sciences, Jawaharlal Nehru University, New Delhi, India-110067 6 2- Present Address 7 Dr. Sarah Naiyer 8 Department of Immunology and Microbiology 9 University of Illinois at Chicago, USA 10 Email: [email protected], [email protected] 11 12 3- Present Address 13 Prof. Sudha Bhattacharya 14 Ashoka University, Rajiv Gandhi Education City, Sonipat, Haryana, India -131029 15 Email: [email protected] 16 17 18 *-Corresponding author 19 1- Present Address 20 Dr. Nishant Singh 21 Department of Urology, University of Pittsburgh, Pittsburgh, PA-USA 15213 22 Email: [email protected], [email protected] 23 †- Share equal first author 24 25 26 bioRxiv preprint doi: https://doi.org/10.1101/2020.06.03.131367; this version posted June 12, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. 27 Abstract 28 Entamoeba Histolytica, a pathogenic parasite, is the causative organism of amoebiasis and uses 29 human colon to complete its life cycle. -
2016 Art103.Pdf
Published Online on 28 September 2016 Proc Indian Natn Sci Acad 82 No. 4 September 2016 pp. 1325-1338 Printed in India. ACADEMY NEWS INSA MEETINGS Science, Bengaluru. Several meetings were held during July 25-29, 2016 For developing new classes of Li- and Na- in the Academy premises. These included meetings cathode materials for next generation battery of the different Sectional Committees for and storage application. recommending names of new Fellows and Young 4. Dr Sivaraman Bhalamurugan (b 29.03.1981), Scientist Awardees to be elected by the Council of PhD, Atomic Molecular and Optical Physics the Academy. The Advisory Boards for the various Division, Physical Research Laboratory, INSA Awards also met. These were followed by Ahmedabad. meetings of the Council and General Body on July 29, 2016. For his contributions in low temperature astrochemistry and planetary science and to INSA Medal for Young Scientists 2016 understand the occurrence of IC objects on The Council at its meeting during July 28-29, 2016 planetary surfaces. approved the award of INSA Medal for Young 5. Dr Ashima Bhaskar (b 23.07.1982), PhD, Scientist 2016 to 22 young researchers below the age National Institute of Immunology, New Delhi. of 35. The award carries a medal, a certificate and cash prize of Rs. 25,000. For developing a genetic biosensor to measure cellular and sub-cellular redox changes in HIV/ The following 22 young scientists were selected Mtb/HIV-TB infected macrophages that for the INSA Medal for Young Scientists. provides meaningful numerical indicators of 1. Dr Nazia Abbas (b 18.08.1982), PhD, Plant redox potential changes required to induce HIV- Biotechnology Division, Indian Institute of 1 reactivation from persistence. -
Recent Advances in Biology: RNA Interference, Drug Entamoeba
F1000Research 2016, 5(F1000 Faculty Rev):2578 Last updated: 17 JUL 2019 REVIEW Recent advances in Entamoeba biology: RNA interference, drug discovery, and gut microbiome [version 1; peer review: 4 approved] Pedro Morgado1*, Dipak Manna1*, Upinder Singh1,2 1Division of Infectious Diseases, Department of Internal Medicine, Stanford University School of Medicine, Stanford, California, USA 2Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA * Equal contributors First published: 26 Oct 2016, 5(F1000 Faculty Rev):2578 ( Open Peer Review v1 https://doi.org/10.12688/f1000research.9241.1) Latest published: 26 Oct 2016, 5(F1000 Faculty Rev):2578 ( https://doi.org/10.12688/f1000research.9241.1) Reviewer Status Abstract Invited Reviewers In recent years, substantial progress has been made in understanding the 1 2 3 4 molecular and cell biology of the human parasite Entamoeba histolytica, an important pathogen with significant global impact. This review outlines version 1 some recent advances in the Entamoeba field in the last five years, published focusing on areas that have not recently been discussed in detail: (i) 26 Oct 2016 molecular mechanisms regulating parasite gene expression, (ii) new efforts at drug discovery using high-throughput drug screens, and (iii) the effect of gut microbiota on amoebiasis. F1000 Faculty Reviews are written by members of the prestigious F1000 Faculty. They are Keywords Entamoeba , amoebiasis , parasite , protozoa commissioned and are peer reviewed before -
Annual Report (1 April 2003 to 31 March 2004)
JAWAHARLAL N EHRU U NIVERSITY 34th Annual Report (1 April 2003 to 31 March 2004) New Delhi-110067 Contents 1-5 6-12 13-15 16-217 1. School of Arts and Aesthetics (SA&A) 16-18 2. School of Computer & Systems Sciences (SC&SS) 19-23 3. School of Environmental Sciences (SES) 24-36 4. School of International Studies (SIS) 37-69 5. School of Information Technology (SIT) 69-72 6. School of Language, Literature & Culture Studies (SLL&CS) 73-104 7. School of Life Sciences (SLS) 105-117 8. School of Physical Sciences (SPS) 118-125 9. School of Social Sciences (SSS) 126-197 10. Centre for Biotechnology(CBT) 198-202 11. Centre for the Study of Law & Governance (CSLG) 203-208 12. Centre for Sanskrit Studies (CSS) 209-214 13. Centre for Molecular Medicine (CMM) 215-217 218-219 220-226 227-228 229-230 231-234 235-236 237-238 1. University Library 237 2. University Science Instrumentation Centre 238 3. University Employment Information & Guidance Bureau 238 239-247 239-247 A. University Court 243 B. Executive Council 244-247 C. Academic Council 239-241 D. Finance Committee 247 248-262 A. Faculty Members 248-258 B. Professor Emeritus 259 C. Faculty Members Appointed 260-261 D. Faculty Members Finally Retired after Re-employment 261 E. Faculty Members Retired on Superannuation 262 F. Faculty Members Resigned/Retired Voluntarily 262 G. Faculty Members Re-employed 262 263-302 A. Ph.D. 263-278 B. M. Phil 279-301 C. M. Tech 302 Officers of the University (As on 31.3.