Anti-CTNNBL1 Antibody (ARG57471)

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Product datasheet [email protected] ARG57471 Package: 100 μl anti-CTNNBL1 antibody Store at: -20°C Summary Product Description Mouse Monoclonal antibody recognizes CTNNBL1 Tested Reactivity Hu Tested Application FACS, ICC/IF, IHC-P Host Mouse Clonality Monoclonal Isotype IgG1 Target Name CTNNBL1 Antigen Species Human Immunogen Purified recombinant fragment of Human CTNNBL1 (aa. 390-557) expressed in E. coli. Conjugation Un-conjugated Alternate Names C20orf33; dJ633O20.1; Beta-catenin-like protein 1; P14L; Nuclear-associated protein; PP8304; NAP; Testis development protein NYD-SP19 Application Instructions Application table Application Dilution FACS Assay-dependent ICC/IF Assay-dependent IHC-P Assay-dependent Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. Calculated Mw 65 kDa Properties Form Liquid Purification Purified Buffer PBS and 0.05% Sodium azide. Preservative 0.05% Sodium azide Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. Note For laboratory research only, not for drug, diagnostic or other use. www.arigobio.com 1/3 Bioinformation Gene Symbol CTNNBL1 Gene Full Name catenin, beta like 1 Background The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. The encoded protein is also a nuclear localization sequence binding protein, and binds to activation-induced deaminase and is important for antibody diversification. This gene may also be associated with the development of obesity. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Jul 2013] Function Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis. [UniProt] Images ARG57471 anti-CTNNBL1 antibody ICC/IF image Immunofluorescence: MCF7 cells stained with ARG57471 anti- CTNNBL1 antibody (green). DRAQ5 fluorescent DNA dye (blue). ARG57471 anti-CTNNBL1 antibody FACS image Flow Cytometry: HeLa cells stained with ARG57471 anti-CTNNBL1 antibody (right histogram) and negative control (left histogram). www.arigobio.com 2/3 ARG57471 anti-CTNNBL1 antibody IHC-P image Immunohistochemistry: Paraffin-embedded Human esophageal cancer tissue stained with ARG57471 anti-CTNNBL1 antibody. www.arigobio.com 3/3 Powered by TCPDF (www.tcpdf.org).

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Coupling of Spliceosome Complexity to Intron Diversity
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