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SCELSE's Annual Scientific Retreat JAN 2019 NEW PROGRAMMES AT SCELSE’S 7TH SCIENTIFIC RETREAT CELSE’s annual scientific retreat marked its seventh year on the Sfirst of November 2018 at the Amara Sanctuary Resort Sentosa. Situated metres away from beach-goers and rollercoaster riders, the Centre’s researchers had equal thrill sharing their work and discovering that of their peers in the resort’s grand ballroom over two days. This year’s scientific retreat was noted for the inclusions of a few novel events on its agenda, notably the return of breakout sessions since 2016 and a recycled poster session. Following convention, Centre Director Prof. Staffan Kjelleberg gave the welcome address and shared the SCELSE at the end of the 7th scientific retreat vision for SCELSE that will be enabled by the extended funding beyond year- of higher learning, government Colleagues seized their chance to 10 of the centre. agencies and businesses to address seek the expertise of their peers or issues of biofilm detection and control share their own during the talks. Dr Prof. Kjelleberg also announced the for industry needs. Both will be Foo Yong Hwee shared his search set-up of a collaboration between launched in February 2019. for those who work with aptamers, SCELSE and the National Biofilm while Dr Artur Matysik exposed the Innovation Centre (NBIC) in the UK. Amid the news of exciting pitfalls in image acquisition and In addition, the upcoming Singapore developments, there were also analysis. Pictures of Pablo, his cat National Biofilm Consortium (SNBC) farewells to address, namely the with a grayscale coat proved to be brings together researchers, institutes departures of SCELSE’s deputy director popular and useful in illustrating his Prof. Yehuda Cohen, deputy research recommendations on achieving better director A/Prof. Yang Liang, and Assist. images. Taking the opportunity to Prof Enrico Marsili (see page 5). remind the 150-strong audience of a Calendar pertinent issue in science, Dr Matysik Learning from bacteria also made a call out to inclusivity with Conferences in 2019 suggestions on using tones friendly The scientific programme opened to the colour-blind when producing with a talk that many from SCELSE microscopy images. 21-22 Feb: World Congress were looking forward to and given on Microbiology & Applied by new visiting professor, Prof. Alain Novel programmes Microbiology. Paris, France. Filloux from the MRC Centre for Abstract deadline: 07 Feb 2019. Molecular Bacteriology and Infection There were also smaller breakout Registration deadline: 14 Feb 2019 at Imperial College London. sessions that allowed for more intensive discussions and interactions. 10-14 Mar: Keystone Conference - Sharing his research on the The sessions ranged from the technical Microbiome: Chemical Mechanisms capabilities of the Pseudomonas – imaging methods, options and and Biological Consequences (C3). aeruginosa type VI secretion system as applications by Prof. Peter Török – to Québec, Canada. Discounted an antibacterial weapon, Prof. Filloux oft-neglected skills in the field, such highlighted how the mechanism may registration deadline: 16 Jan 2019 as Dr Sean Booth and Dr Viduthalai contribute to the manipulation of the Rasheedkhan Regina’s session on microbial community in environments asking questions in scientific seminars. 08-11 Apr: The Microbiology such as the human gut. Society Annual Conference 2019. “For the last couple of years, we’ve Belfast, UK. Early bird registration “I focused on a particular set of had a talk-heavy programme,” admits deadline: 4 Mar 2019 toxins in the talk, but this is an on- Dr Rohan Williams, head of the going project,” says Prof. Filloux. “The Integrative Analysis Unit and one 07-11 Jul: 8th Congress of European overall message I wanted to convey of the retreat organisers. “We have Microbiologists - FEMS 2019. about type VI’s manipulation of the rebalanced it with new programmes Glasgow, Scotland. microbial population was that we can so there is something catering to learn from them and develop clever everyone.” Abstract deadline: 15 Jan 2019. strategies to fight against bacterial Registration deadline: 30 Jun 2019 pathogens in the same way other Long-time attendees of the retreat bacteria fight each other,” he explains. favoured the new (cont. on next page) QUORUM JAN 2019 Dr Artur Matysik’s pet cat Pablo was well received as a sample illustration (from left) Dr Sumitra Debina Mitra, Samarpita Roy, during a presentation on acquiring better microscopy images Dr Irina Afonina and Dr Lucinda Doyle (cont. from previous page) agenda. “This new concept of questions, Prof. Zehnder regaled retreat participants with recyclable poster sessions is a good platform for people to his history as a young researcher. Recalling one of his know what others have presented at various conferences first conferences, he spoke of his surprise at an attendee and it’s good to know what they’re doing,” says research who announced publicly that they did not understand his associate Krithika Arumugam, who has attended every presentation. He realised that it was an opportune moment retreat since SCELSE began. to elucidate his talking points to audience members who might not have dared to ask for clarification, and he was First-year PhD student Omkar Shashikan Kulkarni was grateful for the attendee’s question. taken in by his first experience of the retreat. “It’s been fun and I liked Tan Wee Boon’s talk on transposon sequencing, While Prof. Zehnder was impressed by the work which they used to create mutant libraries and screen entire presented at the retreat, the seamless run of its programme libraries using a high throughput technique,” says Omkar. “I also has to be credited to the corporate services staff who think it’s a really good technology and when you integrate sat quietly at the back of the ballroom. it with something like microbiomes or microbial ecology, it could give you good insights into these fields,” he adds. To that end, many thanks to Ying Ting, Nathasha, Allen, Rehan, Patrick, Smitha, Wey Yeeng, Kartini, Sow Chin Giving thanks to audiences and Soon Lay for the behind the scenes work; Dr Rohan Williams, A/Prof. Scott Rice, Dr Bae Sung Woo, A/Prof. The retreat closed with an adherence to tradition, with Kimberly Kline, A/Prof. Yang Liang for organising; students final remarks given by the SAB Chair, Prof. Alexander and everyone else who have contributed to the retreat in Zehnder. With reference to the breakout session on asking their own way. RESEARCH UPDATE Alarmed zebrafish, air in homes projects receive NIMBELS grant cientists at SCELSE and the Lee Kong Chian School of Medicine (LKC Medicine) will be keeping an (from left) SCELSE research director Prof. Michael Givskov and eye on fearful zebrafish over the next two years. A visiting professor Prof. Alain Filloux happy at lunch S project between A/Prof. Suresh Jesuthasan and Prof. Peter Török, director of the SCELSE imaging facility, that seeks to illuminate the neurological basis of fear responses in zebrafish was awarded the NIMBELS grant in November 2018. The grant is aimed at facilitating joint research projects between two different institutions. The seed fund will provide up to $200,000 SGD over a two-year period. The shortlisted project involves the development of an imaging system to characterise the neural circuits that mediate the alarm response in zebrafish. Aggrieved zebrafish is not the only focus of SCELSE-LKC Medicine joint research in the slew of NIMBELS grant (from left) A/Prof. Diane McDougald, Prof. Hans Curt-Flemming, Prof. projects. Asst Prof. Sanjay Chotirmall and SCELSE’s research Givskov, Dr Rohan Williams, Prof. Staffan Kjelleberg, Prof. Stefan Wuertz, Prof. director of the Meta-‘omics & Microbiomes cluster Prof. Peter Steinberg, Prof. Alexander Zehnder, Prof. Peter Little, Prof. Peter Török, Stephan Schuster are leading the charge in investigating Prof. Jürg Keller, A/Prof. Paul MacAry, A/Prof. Sanjay Swarup indoor air microbiomes and its links to respiratory disease. 2 SINGAPORE CENTRE FOR ENVIRONMENTAL LIFE SCIENCES ENGINEERING | www.scelse.sg QUORUM JAN 2019 PUBLICATION PROFILE CONFERENCE REPORT Sequencing tropical air bacterium here is something in the air; in fact, there are plenty and more yet to be sequenced as far as the research of TSCELSE’s air microbiome programme goes. A collection of papers on the complete genome sequence of various bacterium in Singapore’s tropical air space was published in Genome Announcements by the American Society for Microbiology between May to July 2018. The selection of sequenced bacterium includes Acinetobacter indicus1, Lelliottia nimipressuralis2, Staphylococcus haemolyticus3, Pseudomonas stutzeri4, Acinetobacter tyria in the southeast of Austria is known as the schindleri5, Geobacillus thermoleovorans6, Serratia country’s ‘Green Heart’ and its most fertile state. For marcescens7, Bacillus velezensis8 and Pantoea ananatis9. Sthe last two years, researchers have descended upon its municipiality of Vorau or rather, have ascended its peaks This work by the Centre’s air microbiome group for the annual Mountain Village Science Series (MOVISS) contributes to an open access public database on new conference. SCELSE research associate Ms Saw Nay Min Min Thaw was one such hiker and conference participant genome sequences and methodologies for attaining and in September 2018. She shares her experience of discussing assembling them. More importantly, the functional analysis metabolomics in the mountains: and annotation results of these sequenced bacterium
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