HILARY ARNOLD GODWIN born Hilary Joan Arnold, December 1, 1967 Department of Environmental Health Sciences School of Public Health University of California, Los Angeles 66-062B CHS; BOX 951772 Los Angeles, CA 90095 phone: (310) 794-9112 fax: (310) 794-2106 email: [email protected]

EDUCATION NIH Postdoctoral Fellow, School of Medicine, 1994-1996 Ph.D. in Physical Chemistry, , 1994. B.S. in Chemistry with Honors, University of , 1989.

PROFESSIONAL EXPERIENCE 2007-present Chair, Environmental Health Sciences Department, University of California at Los Angeles 2006-present Professor, University of California at Los Angeles Environmental Health Sciences Department, School of Public Health 2002-present Howard Hughes Medical Institute (HHMI) Professor 2004-2006 Chair, Department of Chemistry, 2003-2004 Associate Chair, Department of Chemistry, Northwestern University 2002-2004 Dow Chemical Company Research Professor in Chemistry, Northwestern University 2001-2006 Associate Professor, Northwestern University Department of Chemistry and Department of Biochemistry, Molecular Biology, and Cell Biology (Joint Appointment) 1996-2001 Assistant Professor, Northwestern University Department of Chemistry and Department of Biochemistry, Molecular Biology, and Cell Biology (Joint Appointment since 1998)

HONORS & AWARDS Howard Hughes Medical Institute (HHMI) Professor (2002-present) Paul Saltman Award (2001) Camille Dreyfus Teacher-Scholar Award (2000) Alfred P. Sloan Research Fellowship (2000) National Science Foundation CAREER Award (1999) Burroughs Wellcome Fund Toxicology New Investigator Award (1998) Camille and Henry Dreyfus New Faculty Award (1996) National Institutes of Health Postdoctoral Research Fellowship (1994-1996) Stanford Centennial Teaching Assistant Award (1992) National Science Foundation Graduate Research Fellowship (1989-1992) January 24, 2008 Hilary Arnold Godwin

Phi Beta Kappa (1989)

RESEARCH INTERESTS Metal ions in biological systems: molecular mechanism of lead toxicity; biophysical studies on neurological and hormonal signaling; development of fluorescent sensors for metal ions; toxicogenomics and proteomics; public health impacts of climate change.

PUBLICATIONS 1. “(E)-1-Benzyl-3-(1-iodoethylidene)piperidine: Nucleophile Promoted Alkyne-Iminium Ion Cyclizations” Arnold, H; Overman, L.E.; Sharp, M. J.; Witschel, M. C. Organic Syntheses 1992, 70, 111-119. 2. “Heterometallic and Homometallic Ruthenium and Osmium Double Bonds in Metalloporphyrin and Metallotetraazaporphyrin Dimers” Collman, J. P.; Arnold, H. J.; Fitzgerald, J. P.; Weissman, K. J. J. Am. Chem. Soc. 1993, 115, 9309-9310. 3. “Multiple Metal-Metal Bonds in 4d and 5d Metal-Porphyrin Dimers” Collman, J. P.; Arnold, H. J. Acc. Chem. Res. 1993, 26, 586-592. 4. “Delta Bonds and Rotational Barriers in 4d and 5d Metal-Porphyrin Dimers” Collman, J. P.; Arnold, H. J. J. Cluster Science 1994, 5, 37-66. 5. “Heterometallic Mixed Triad Multiple Bonds in Metal-Porphyrin Dimers” Collman, J. P.; Arnold, H. J.; Weissman, K. J.; Burton, J. M. J. Am. Chem. Soc. 1994, 116, 9761- 9762. 6. “A Fluorescent Zinc Sensor Based on Metal Induced Peptide Folding” Godwin, H. A. and Berg, J. M. J. Am. Chem. Soc. 1996, 118, 6514. 7. “Lessons from Zinc-Binding Peptides” Berg, J. M. and Godwin, H. A. Ann. Rev. Biophys. Biomol. Struct. 1997, 26, 357-71. 8. “Magnetic Properties of Group 8 Metal-Metal Bonded Porphyrin and Tetraazaporphyrin Dimers” Godwin, H. A.; Collman, J. P.; Marchon, J.-C.; Maldivi, P.; Yee, G. T.; Conklin, B. J. Inorg. Chem. 1997, 36, 3499-3502. 9. “Lead-Fingers: Pb(II)-Binding to Structural Zinc-Binding Domains Determined Directly By Monitoring Lead-Thiolate Charge Transfer Bands” Payne, J. C.; ter Horst, M. A.; Godwin, H. A. J. Am. Chem. Soc. 1999, 121, 6850-6855. 10. “A Selective, Ratiometric, Fluorescent Sensor for Pb2+” Deo, S.; Godwin, H. A. J. Am. Chem. Soc. 2000, 122, 174-175. 11. “207Pb-1H Two-Dimensional NMR Spectroscopy: A Useful New Tool for Probing Lead(II) Coordination Chemistry” Claudio, E. S.; ter Horst, M. A.; Forde, C. E.; Stern, C.; Zart, M. K.; Godwin, H. A. Inorg. Chem. 2000, 39, 1391-1397. 12. "Calcium Triggers An Intramolecular Association Between The C2 Domains of Synaptotagmin" Garcia, R. A.; Forde, C. A.; Godwin, H. A. Proc. Natl. Acad. Sci. U.S.A. 2000, 97, 5883-5888. 13. "High-Yield Expression and Purification of Recombinant Proteins In Bacteria: A Versatile Vector For Overexpression Of Glutathione S-Transferase Fusion Proteins Containing Two Protease Cleavage Sites" Sehgal, B.; Dunn, R.; Hicke, L.; Godwin, H. A. Anal. Biochem. 2000, 281, 232-234. 14. “The Biological Chemistry of Lead” Godwin, H. A. Curr. Opin. Chem. Biol. 2001, 5, 223-227. 15. “Synaptotagmin I is a Molecular Target for Lead” Bouton, C. M. L. S.; Frelin, L. P.;

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Forde, C. E.; Godwin, H. A.; Pevsner, J. J. Neurochem. 2001, 76, 1724-1735. 16. “Fundamental Coordination Chemistry, Environmental Chemistry, and Biochemistry of Lead(II)” Claudio, E. S.; Magyar, J. S.; Godwin, H. A. Prog. Inorg. Chem 2003, 51, 1- 144. 17. “Spectropotentiometric Analysis of Metal Binding to Structural Zinc-Binding Sites: Accounting Quantitatively for pH and Metal Ion Buffering Effects” Magyar, J. S.; Godwin, H. A. Anal. Biochem. 2003, 320, 39-54. 18. “Spectroscopic Determination of the Binding Affinity of Zinc to the DNA-Binding Domains of Nuclear Hormone Receptors” Payne, J. C;. Rous, B. W.; Tenderholt, A. L; Godwin, H. A. Biochemistry, 2003, 42, 14214-14224. 19. “High Metal Concentrations Are Required for Self-association of Synaptotagmin II” García, R. A. and Godwin, H. A. Biophys. J., 2004, 86, 2455-2466, 20. “Color My Nanoworld” McFarland, A. D.; Haynes, C. L.; Van Duyne, R.; Godwin, H. A. J. Chem. Ed. 2004, 81, 544A-544B. 21. “Spectroscopic Determination of the Thermodynamics of Cobalt and Zinc Binding to GATA Proteins” Ghering, A. B.; Shokes, J. E.; Scott, R. A.; Omichinski, J. G.; Godwin, H. A. Biochemistry, 2004, 43, 8346-8355. 22. “Nanopatterning with Lithography” McFarland, A. D.; Haynes, C. L.; Van Duyne, R.; Godwin, H. A. J. Chem. Ed. 2005, 82, 768A-768B 23. “Spectroscopic and Functional Determination of the Interaction of Pb2+ with GATA Proteins” Ghering, A. B.; Jenkins, L. M. M.; Schenck, B. L.; Deo, S.; Mayer, R. A.; Pikaart, M. J.; Omichinski, J. G.; Godwin, H. A. J. Am. Chem. Soc. 2005, 127, 3751- 3759. 24. “Reexamination of Lead(II) Coordination Preferences in Sulfur-Rich Sites: Implications for a Critical Mechanism of Lead Poisoning” Magyar, J. S. ; Weng, T.-C.; Stern, C. M.; Dye, D. F.; Rous, B. W.; Payne, J. C.; Bridgewater, B. M.; Mijovilovich, A.; Parkin, G.; Zaleski, J. M.; Penner-Hahn, J. E.; Godwin, H. A. J. Am. Chem. Soc. 2005, 127, 9495- 9505. 25. “Teaching Undergraduates at the Interface of Chemistry and Biology: Challenges and Opportunities” Godwin, H. A.; Davis, B. L. Nature Chem. Biol. 2005, 1, 176-180. 26. “Preparation of Media and Buffers with Soluble Lead (Pb2+)” Mayer, R. A.; Godwin, H. A. Anal. Biochem. 2006, 356, 142-144. 27. “Characterization of the first N2S(alkylthiolate)lead compound: A model for 3-coordinate lead in biological systems” Andersen, R. J.; diTargani, R. C.; Hancock, R. D.; Stern, C. L.; Goldberg, D. P.; Godwin, H. A. Inorg. Chem. 2006, 45, 16574-6576. 28. “A recombinant courtship pheromone affects sexual receptivity in a plethodontid salamander” Houck, L.; Watts, R.; Arnold, S.; Bowen, K.; Kiemnec, K.; Godwin, H.; Feldhoff, P.; Feldhoff, R. Chem. Senses, in press. 29. Haynes, C.; McFarland, A.; Van Duyne, R.; Godwin, H. Nanoscience and Nanotechnology Module, Materials World Modules; Northwestern University: Evanston, Illinois, in press.

PROFILES & RESEARCH HIGHLIGHTS • “Hilary Godwin: Alone in Good Company” Austin, J. Science Next Wave (http://nextwave.sciencemag.org/cgi/content/full/2001/07/11/6?). • “Leading The Fight Against Lead Poisoning” Fellman, M. CrossCurrents (Northwestern

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University Weinberg College of Arts and Sciences), Fall 2001, 6-9. • “Million-Dollar Plums For Teaching Biology” Stokstad, E. Science, 2002, 297, 2190-2191. • “2 College Teachers to Receive $1 Million” Becker, R. Chicago Tribune, September 18, 2002. • “Godwin Receives $1M from Howard Hughes Medical Institute” Northwestern University Observer, Oct. 10, 2002. • “WOW Factor Goes Predoctoral” Wilkinson, S. L. Chem. & Eng. September 30, 2002, 32-33. • “Research on Lead Poisoning Will Send Students Into Communities” Guy, S. Chicago Sun- Times, February 5, 2003. • “Chemistry and Community” Strawn, S. The Daily Northwestern, July 17, 2003. • “’The Frontiers of Inorganic Chemistry’ – A Workshop” Eisenberg, R. Inorg. Chem. 2003, 42, 2479. • “Women Scientists in 2003” Deneen, N. CrossCurrents (Northwestern University Weinberg College of Arts and Sciences), Fall 2003, 10-15. • “Summer Scientists Get Head Start on Freshman Year” Fellman, M. Northwestern University Observer, November 6, 2003. • “College Freshman Get Ahead with Lead” Donovan, J. L. Howard Hughes Medical Institute Bulletin, Spring 2004, 32-33. • “Getting the Lead Out” Jegalian, K. Findings (National Institute of General Medical Sciences), March 2005, 8-13. • “Lead Binding Reexamined” Barry, D. Chem. & Eng. News 2005, 83, 13. • “Faculty Profile: Hilary Godwin – Preventing Children from Being Lead Astray” UCLA Public Health Magazine, June 2007, 12-13. • “Gathering Storm: The Health Effects of Global Climate Change” UCLA Public Health Magazine, November 2007, 4-9.

PRESENTATIONS AT NATIONAL AND INTERNATIONAL MEETINGS Presentation, NATO ASI on Energetics of Organometallic Species, “Synthesis of Heterometallic Metal-Metal Bonded Porphyrin Dimers,” H. J. Arnold, J. P. Collman, and J. P. Fitzgerald, Portugal, September 1991. Lecture, American Chemical Society Meeting, “Heterometallic Metal-Metal Bonded Porphyrin Dimers,” H. J. Arnold, J. P. Collman, and J. P. Fitzgerald, San Francisco, California, April 1992. Invited Speaker, 75th Canadian Chemical Conference, “Chemistry 32: The Frontiers of Chemical Science,” H. J. Arnold, J. P. Collman, and R. N. Zare, Edmonton, Alberta, May 1992. Lecture, 75th Canadian Chemical Conference, “Heterometallic Metal-Metal Bonded Porphyrin Dimers,” H. J. Arnold, J. P. Collman, and J. P. Fitzgerald, Edmonton, Alberta, May 1992. Poster presented at Inorganic Biochemistry Summer Workshop, “Fluorescent Peptides for Monitoring Zn(II) Levels In Vivo,” H. J. Arnold and J. M. Berg, Athens, Georgia, July 1996. Poster presented at American Chemical Society, “Fluorescent Peptides for Monitoring Zn(II) Levels In Vivo,” H. J. Arnold and J. M. Berg, Chicago, Illinois, August 1996. Poster presented at Metals in Biology Gordon Conference, “Fluorescent Peptides for Monitoring Zn(II) Levels In Vivo,” H. J. Arnold and J. M. Berg, Ventura, California, January 1996. Poster presented at Metals in Biology Gordon Conference, “Lead Fingers: Spectroscopic Studies of Lead-Protein Interactions,” J. C. Payne, M. A. ter Horst, and H. A. Godwin, Ventura, California, January 1997.

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Poster presented at the Burroughs Wellcome Fund New Investigators Meeting, “Biophysical Approaches to Lead Toxicology: Biochemistry, Detection, and Chelation of Pb(II),” Blaine, Washington, July 1998. Lecture, American Chemical Society Meeting, “Spectroscopic Studies of Lead Binding to Zinc Proteins,” H. A. Godwin, J. C. Payne, M. A. ter Horst, S. Padia, Boston, Massachusetts, August 1998. Poster presented at XXXIII International Conference on Coordination Chemistry, “Spectroscopic Studies of the Interactions Between Pb(II) and Zinc-Binding Sites in Proteins ,” H. A. Godwin, J. C. Payne, M. A. ter Horst, S. Padia, Forence, Italy, September 1998. Poster presented at Metals in Biology Gordon Conference, “Myths, Misconceptions, and the Molecular Mechanism(s) of Lead Poisoning,” H. A. Godwin, J. C. Payne, C. A. Forde, M. A. ter Horst, M. K. Zart, E. S. Claudio, B. Sehgal, S. Deo, and A. Reynolds, Ventura, California, January 1999. Lecture, American Chemical Society Meeting, “207Pb NMR Spectroscopy of Amido Derivatives of Ethylenediaminetetraacetic Acid: Novel Water-Soluble Chelators for Pb(II),” H. A. Godwin, M. A. ter Horst, C. E. Forde, E. S. Claudio, M. K. Zart, Anaheim, California, March 1999. Invited Speaker, Ninth International Conference on Biological Inorganic Chemistry (ICBIC), "Why is lead toxic? Unraveling the molecular mechanism(s) of lead poisoning" Minneapolis, Minnesota, July 12, 1999. Poster presented at Inorganic Chemistry Gordon Conference, “Lead Poisoning: How A Chemical Approach Can Shed New Light On An Ancient Problem,” H. A. Godwin, J. C. Payne, M. A. ter Horst, Providence, Rhode Island, July 1999. Poster presented at Metals in Biology Gordon Conference, “How Calcium Mediates Neurotransmission: Calcium Triggers an Intramolecular Association Between the C2 Domains of Synaptotagmin,” R. A. Garcia, C. E. Forde, and H. A. Godwin, Ventura, California, January 2000 Lecture, American Chemical Society Meeting, “Lead Poisoning: Using Chemistry to Shed New Light on an Ancient Problem,” H. A. Godwin, San Francisco, California, March 2000. Poster presented at Chicago Signal Transduction Symposium, “How Calcium Mediates Neurotransmission: Calcium Triggers an Intramolecular Association Between the C2 Domains of Synaptotagmin,” R. A. Garcia, C. E. Forde, and H. A. Godwin, Chicago, Illinois, May 2000 Invited Speaker, Bioanalytical Sensors Gordon Research Conference, "Lead Poisoning and Detection” Andover, NH, July, 2000. Invited Speaker (Paul Saltman Award Lecture), Metals in Biology Gordon Conference, "Why is lead toxic? Unraveling the molecular mechanism(s) of lead poisoning" Ventura, California, January, 2001. Invited Speaker, Environmental Bioinorganic Chemistry Gordon Conference, "Molecular Toxicity and Toxicogenomics of Lead" Bates College, Maine, June 2004. Invited Speaker, 11th International Conference on the Coordination Chemistry and Organometallic Chemistry of Germanium, Tin, and Lead, "Why is lead toxic? Unraveling the molecular mechanism(s) of lead poisoning" Santa Fe, New Mexico, June-July 2004. Invited Speaker, Inorganic Reaction Mechanisms Gordon Conference, "Kinetics of metal binding and substitution in zinc-finger peptides" Ventura, California, February, 2005.

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Invited Speaker, AAAS National Meeting, “Novel approaches for the retention of science students from diverse backgrounds” Washington, D. C., February, 2005. Poster presented at Metals in Biology Gordon Conference, “Molecular Link Between Lead Stress and Iron Homeostasis in S. cerevisiae,” D. Ivanov, E. Suarez, B. Davis, H. Jiang,, and H. A. Godwin, Ventura, California, January 2007 Invited Speaker, Western Regional American Chemical Society Meeting, D. Ivanov, E. Suarez, and H. A. Godwin, San Diego, California, October 2007

SEMINARS 1993 Centre d'Etudes Nucleares de Grenoble, Grenoble, France 1994 Department of Chemistry, Northwestern University 1996 Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University; Kalamazoo College, Kalamazoo, Michigan; Hope College, Holland, Michigan 1997 Department of Chemistry, Northwestern University, Evanston, Illinois; Department of Chemistry, Loyola University, Chicago, Illinois; Department of Chemistry, Illinois State University, Normal, Illinois; Department of Chemistry, Illinois Institute of Technology, Chicago, Illinois 1998 Department of Civil Engineering, Northwestern University, Evanston, Illinois; Department of Chemistry, Johns Hopkins University, Baltimore, Maryland; Kennedy Krieger Institute/ Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Chemistry, Grand Valley State University, Grand Rapids, Michigan; Department of Chemistry, University of North Carolina, Chapel Hill, North Carolina; Department of Microbiology and Immunology, University of Illinois, Chicago, Illinois 1999 Department of Geology, Northwestern University, Evanston, Illinois; Symposium: Materials Research & Education at the Dawn of the New Milenium, Northwestern University, Evanston, Illinois 2000 Department of Chemistry, Bowling Green State University, Bowling Green, Ohio; Department of Chemistry, University of Missouri, Saint Louis, Missouri; Faculty of Toxicology, College of Veterinary Medicine, Texas A & M University, College Station, Texas; Department of Chemistry, Dartmouth College, Hanover, New Hampshire; Department of Chemistry, the Ohio State University, Columbus, Ohio; Center for Environmental BioInorganic Chemistry (CEBIC) Summer Conference, Princeton University, Princeton, New Jersey;. Department of Chemistry, Georgia State University, Atlanta, Georgia; Center for Metalloenzyme Studies, University of Georgia, Athens, Georgia; Department of Chemistry, Emory University, Atlanta, Georgia; Department of Chemistry, Purdue University, West Lafayette, Indiana; Department of Chemistry, Massachusetts Institute of Technology, Boston, Massachusetts; Department of Chemistry, Calvin College, Grand Rapids, Michigan; Department of Chemistry, Hope College, Holland, Michigan; Meeting of the Chicago Chapter of Iota Sigma Pi, Glenview, Illinois 2001 Mathfest, Fremd High School, Palatine, Illinois; Department of Chemistry, University of California, Los Angeles, California; Department of Chemistry, California Institute of Technology, Pasadena, California; Department of Chemistry, Boston College, Boston, Massachusetts; Department of Chemistry, University of Wisconsin, Madison, Wisconsin; Department of Chemistry, University of California, Berkeley, California; Department of Chemistry, Stanford University, Stanford, California; Department of

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Chemistry, Indiana University, Bloomington, Indiana; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois; Biophysics Program, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas; Department of Chemistry, Texas A & M University, College Station, Texas; Department of Chemistry, University of Texas, Austin, Texas 2002 Department of Chemistry, Michigan State University, East Lansing, Michigan; Department of Chemistry, University of Utah, Salt Lake City, Utah; Department of Chemistry and Biochemistry, Utah State University, Logan, Utah. 2003 Department of Chemistry, University of California Irvine, Irvine, California; Lead America Educational Leadership Conference, Lake Forest, Illinois; Department of Chemistry and Biochemistry, University of Maryland Baltimore County, Baltimore, Maryland; Department of Chemistry and Biochemistry, University of Delaware, Newark, Delaware; Wayne State University, Detroit, Michigan. 2004 Department of Chemistry. University of Missouri, Kansas City, Missouri; Department of Chemistry, Louisana State University, Baton Rouge, Louisiana; University of Oklahoma, Normal, Oklahoma; Howard Hughes Medical Institute (keynote speaker), Chevy Chase, Maryland; Department of Molecular Pharmacology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Chemistry, University of Illinois Urbana-Champagne, Urbana, Illinois. 2005 Molecular Probes, Eugene, Oregon; Reed College, Portland, Oregon; Department of Chemistry, University of Oregon, Eugene, Oregon; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota; Department of Chemistry, Ball State University; Department of Chemistry, University of Texas at El Paso, El Paso, Texas; Department of Chemistry, Grinnell College. 2006 Department of Chemistry, University of Southern California, Los Angeles, California; Department of Chemistry & Biochemistry, UCLA, Los Angeles, California; Department of Chemistry, University of Michigan, Ann Arbor, Michigan; Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania; Nanotechnology Workshop, Life Sciences Week, University of Missouri, Columbia, Missouri; Symposium on the Nature of Science, Fermilab, Batavia, Illinois. 2007 Lubrizol Corporation, Wiekliffe, Ohio; Department of Chemistry, Case Western Reserve University, Cleveland, Ohio; CEA-CREST Program at California State University Los Angeles, Los Angeles, California; Department of Chemistry, University of California at San Diego, San Diego, California.

GRANTS AND AWARDS 1. National Science Foundation, Graduate Research Fellowship (1989-1992) 2. National Institutes of Health Postdoctoral Fellowship (1994-1996) 3. Camille and Henry Dreyfus New Faculty Award “The Chemistry of Metal Ions in Bioluminescence and Bioremediation” (9/1/96-8/31/01) $25,000 4. Burroughs Wellcome Fund Toxicology New Investigator Award, “Biophysical Approaches to Lead Toxicology: Biochemistry, Detection and Chelation of Pb(II)” (7/1/98-6/31/2001) $195,000 5. National Science Foundation, “Acquisition of a 500 MHz NMR Spectrometer for Chemical Research” P.I. Joseph Lambert (9/1/98-8/31/99) $487,732 6. National Science Foundation CHE-9875341; “CAREER: New Super Ligands for Lead:

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Tight and Selective Pb(II)-Binding Agents” (3/1/99-2/28/04) $495,000 7. National Institutes of Health R01 GM58183 “Spectroscopic Probes of Lead-Protein Interactions” (8/1/99-7/31/04) $754,827 8. National Science Foundation, CHE-9810378, “Institute for Environmental Catalysis” P.I. Peter Stair (9/15/98-8/31/02) $193,153 9. Sloan Research Fellowship, 2000, $40,000 10. Camille Dreyfus Teacher-Scholar Award, 2000, $60,000 11. National Science Foundation/MRSEC DMR-0076097, “Materials Research Center” P.I. Robert Chang (9/1/00-8/31/02) $114,169 12. National Science Foundation, “Workshop: Frontiers of Inorganic Chemistry” (3/1/01- 2/28/02) $59,400 13. National Science Foundation/NSEC, EEC-0118025, “NSEC: Integrated Nanopatterning and Detection Technologies” (Research) P.I. Chad Mirkin 9/1/01-8/31/04 $87,940 14. National Science Foundation/NSEC, EEC-0118025, “NSEC: Integrated Nanopatterning and Detection Technologies” (Education) P.I. Chad Mirkin 9/1/01-8/31/05 $106,747 15. Howard Hughes Medical Institute (HHMI) Professor (9/1/02-8/31/06) $1,000,000 16. Dreyfus Special Grants Program, “Integrating Discovery-Based Learning Modules into the General Chemistry Curriculum “ $15,000. 17. Department of Education , GAANN Program, “National Needs Fellowship In Chemistry At Northwestern University: 2004-2007” $498,132. 18. Clare Boothe Luce Foundation “Clare Boothe Luce Professorship at Northwestern University” (Grant to hire a new faculty member in the Department of Chemistry at Northwestern University) $600,000. 19. Department of Education , GAANN Program, “National Needs Fellowship In Chemistry At Northwestern University: 2006-2009” $633,630. 20. U.S. Department of Housing and Urban Development, Lead Technical Studies Program “Fluorogenic Methods for Detection of Lead on Surfaces” P.I. Roger Lewis (Saint Louis University) 11/1/06-10/31/07, $89,101. 21. National Science Foundation, Center for Environmental Implications of Nanotechnology (CEIN) program “Center for the Environmental Impact of Nanotechnology”, preproposal pending (P.I. Andre Nel) 22. National Institute of Environmental Health Sciences (NIEHS), “Conference: Regional Assessment of the Public Health Impacts of Climate Change”, pending. 23. Southern California Environmental Science Center Pilot Project Program, “Microclimates and Vulnerability to Extreme Heat Events in Los Angeles County”, pending.

PROFESSIONAL ORGANIZATIONS & AFFILIATIONS Council for Chemical Research (2005-2006) American Chemical Society: Inorganic Division, Physical Division Society for Neuroscience Biophysical Society American Association for the Advancement of Science American Association for Women in Science Iota Sigma Pi

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INSITUTE AND CENTER MEMBERSHIP 2007-present Member, Institute for the Environment, UCLA 2007-present Member, California Nanosystems Institute, UCLA 2000-2006 Member, NSF-Nanoscale Science and Engineering Center (NSEC), Northwestern University 2000-2002 NSF – Materials Research Science and Engineering Center (MRSEC), Northwestern University

1998-2002 NSF-Institute for Environmental Catalysis 1997-2006 Member, Lurie Cancer Center, Northwestern University

SERVICE Organizer, “Changing Climate, Changing Lives” Summit (2007) Advisory Board for Committee on the Advancement of Women Chemists (COACh) (2006- present) Review Panel, HHMI Professors Program (2006) Advisory Board for “Science Storms”, Museum of Science and Industry, Chicago, Illinois (2005- present) Panelist, Interviews for Finalists for 2005 National Institutes of Health Director’s Pioneer Award (2005) Nominating Committee for Council for Chemical Research Governing Board (2005) Rotating Member, Special Emphasis Panel – Conflicts in Biological Chemistry and Macromolecular Biophysics, National Institutes of Health (2005) Faculty Advisor, Chicago Area Undergraduate Research Symposium (2005) Rotating Member, BMT Study Section, National Institutes of Health (2003) Essential Science Taskforce, Museum of Science and Industry, Chicago, Illinois (2003-2004) Organizing Committee, Japanese-American Frontiers of Science Meeting, National Academy of Sciences (2003-2004) Freshman Advisor, Northwestern University (2003-2005) Director, Undergraduate Success in Science Program, Northwestern University (2003-present) Director, Education and Outreach Activities, Institute for Nanotechnology/ NSF-Nanoscale Science and Engineering Center (NSEC), Northwestern University (2000-2006). Organizing Committee, Frontiers of Chemistry Meeting sponsored by the American Chemical Society, Durham, New Hampshire, August 24-27, 2002 Co-chair, Symposium on Coordination Chemistry of Metal Metabolism, 224th American Chemical Society National Meeting, Boston, Massachusetts, August 18-22, 2002 Organizing Chair, Symposium on Bioinorganic Chemistry, 34th Great Lakes Regional American Chemical Society Meeting, Minneapolis, Minnesota, June 2-4, 2002 P.I., Frontiers of Inorganic Chemistry Workshop sponsored by the National Science Foundation, Copper Mountain, Colorado, September 8-10, 2001 Faculty Advisor, Northwestern Chapter of Phi Lamda Upsilon (2000-2004) Faculty Associate, Shepard Residential College (1997-2002) Nominations and Symposium Planning Committee for the Division of Inorganic Chemistry of the American Chemical Society (1996)

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COMMITTEES – UCLA Co-Chair, Faculty Search Committee for Director for Center to Combat Emerging Infectious Diseases (2007-present) Executive Committee of the Institute for the Environment (2007-present) Faculty Advisory Committee, Molecular Toxicology Interdepartmental Degree Program (2007- present) Campus Advisory Board for Proposal to Public Utilities Commission on Global Climate Change Institute (2007-present) Chair, Search Committee for High Throughput BSL3 Laboratory Director, School of Public Health (2006-present) Planning Committee for High Throughput BSL3 Laboratory, School of Public Health (2006- present)

COMMITTEES – NORTHWESTERN UNIVERSITY Executive Committee, Institute for Nanotechnology/ NSF-Nanoscale Science and Engineering Center (NSEC), Northwestern University (2003-2006). Search Committee for Chief Financial Officer, Weinberg College of Arts and Sciences (2005) Chair, Chemistry Graduate Advising Committee (2003-2004) Planning Committee for Proteomics and Nanobiotechnology Building (2003-2006) Chemistry Faculty Mentoring Committee (2003-2006) Chemistry Faculty Recruiting Committee (2003-2004) Chair, Chemistry Graduate Admissions Committee (2001-2002) Chair, Search Committee for Freshman Chemistry Laboratory Coordinator (2001) Chemical & Biological Safety Committee (1998-2000; 2002-2005) Chemistry Vision Committee (2000-2002) Chemistry Faculty Recruiting Committee (2000-2001) Chemistry Transition Committee (ad hoc) (2000) Chemistry Research Facilities Committee (1999-2001) Chemistry Space Committee (ad hoc) (1998) Search Committee for Freshman Chemistry Laboratory Coordinator (1998) Graduate School Faculty (1998-present) 600 MHz NMR User Committee (1998-2006) College Scholars Program Board (1998-2001) Trustees Professor Search Committee Chemistry/NBP/BMBCB (1998-2001) Goldwater Scholarship Selection Committee (1998-2000) Member, Chemistry Graduate Admissions Committee (1997-2001)

TEACHING -UCLA Environmental Health 100, Introduction to Environmental Health Sciences (Spring 2007) This course is a required course for all MPH students who are not Environmental Health majors. Texts in 2007: Essentials of Environmental Health by Robert Fris and GIS Tutorial for Health by Kristen Kurland and Wilpen Gorr. The goal of this course is to provide students with an overview of the field of Environmental Health Sciences and for students to learn how to use Geographic Information Systems (GIS) to map and analyze Public Health Data Topics covered in the course include the following: environmental epidemiology, environmental toxicology, environmental policy and regulation, agents of environmental disease and applications of

Page 10 of 10 January 24, 2008 Hilary Arnold Godwin environmental health to water quality, air quality, food safety, solid and liquid waste, and occupational health. Approximate enrollment: 90.

TEACHING -Northwestern University Chemistry 101, General Chemistry (Fall 1999 and Fall 2000) The first course in a three quarter series of general chemistry for science majors. Text in 1999: Chemistry (2nd Edition) by John McMurry and Robert Fay. Text in 2000: Chemistry: The Central Science (8th Edition) by Theodore L. Brown, H. Eugene LeMay, Jr., and Bruce E. Bursten. Topics covered in the course include the following: basic chemical calculation, solution stoichiometry problems, atomic and electronic structure, descriptive chemistry, aqueous chemistry, periodic properties of the elements. Approximate enrollment: 150.

Chemistry 103, General Physical Chemistry (Spring 1997, two sections, each co-taught with Tobin Marks; Spring 1998, two sections; Spring 1999, two sections) The third and final course in general chemistry for science majors. Text: Chemistry (4th Edition) by Steve Zumdahl. Topics covered in the course include the following: chemical equilibrium; equilibria in aqueous solution; chemical kinetics; electrochemistry and oxidation-reduction reactions; coordination chemistry and special topics. Emphasis was placed on examples from environmental chemistry and biochemistry. Approximate enrollment: 350 per quarter.

Chemistry 105, Freshman Seminar: Science and Society (Fall 2003 and Fall 2004) Discussion course for freshmen in the Weinberg College of Arts and Sciences. Text: A Writer's Reference, 5th edition, by Diana Hacker; assorted essays and book chapters on issues related to the topic of Science and Society. Topics covered in the course include the following: what it means to be a scientist, the future of science in our society, nature versus nurture, genetically modified crops, cloning, public policy on infectious diseases. The assignments in this class focus on academic and professional writing. Approximate enrollment: 16.

Chemistry 435, Advanced Inorganic Chemistry (Winter 1997, Winter 2000, and Winter 2001) Special topics graduate level course in bioinorganic chemistry. Text: Bioinorganic Chemistry by Stephen Lippard and Jeremy Berg; original articles from the literature on the role of metal ions in biological systems were assigned as readings and discussed in class. The course had two primary focuses: the structure and function of metalloproteins and the use of spectroscopic techniques in bioinorganic chemistry. The assignments for this class were focused on scientific writing. Approximate enrollment: 20.

Chemistry 436, Readings in Inorganic Chemistry (Fall 2003) Required graduate level course in inorganic chemistry. Text: The ACS Style Guide, 2nd edition, edited by Janet S. Dodd and original articles from the literature. The course has two primary focuses: seminal contributions to the field of inorganic chemistry and research at the frontiers of inorganic chemistry. The assignments for this class focus on critical evaluation of the scientific literature and scientific writing. Approximate enrollment: 30.

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RESEARCH SUPERVISION 2006-present Preceptor, Molecular Toxicology Training Program, University of California at Los Angeles 2006-present Preceptor, Chemistry-Biology Interface Training Program, University of California at Los Angeles 1996-2006 Preceptor, Interdepartmental Biological Sciences Program, Northwestern University

Postdoctoral Fellows: 2006-present Elizabeth Suarez 2004-2006 Benjamin Davis 2002-2004 Simona Dragan 1997-1999 Cameron Forde 1997-1998 Marc ter Horst

Graduate Students: 2007-present Mariam Behbehani, Environmental Health Sciences (M.P.H student) 2007 Herguin Cuevas, Environmental Health Sciences 2004-present Ethan Trana, Chemistry 2004-present Dimitar Ivanov, IBiS 2001-2002 Kylie Barker, Chemistry 2000-present R. Aeryn Mayer, Chemistry, M.S. 2000-2004 Ryan Andersen, IBiS, Ph.D. 1999-2004 Brian Rous, Chemistry, Ph.D. 1998-2006 Elizabeth Suarez (formerly Claudio), Chemistry 1998-2002 John Magyar, Chemistry, Ph.D. 1998-2001 Ricardo Garcia, IBiS, Ph.D. 1998-2003 Amy Ghering, Chemistry, Ph.D. 1997-1998 Matthew Zart, Chemistry M.S. 1997-2002 Sandhya Deo, Chemistry, Ph.D. 1996-2002 John Payne, Chemistry, Ph.D. 1996-2002 Bernd Sehgal, Chemistry, Ph.D. 1996-1997 Russell Scarola, Chemistry M.S.

Undergraduate Researchers: Summer 2005 USS workshop: 17 incoming freshmen and 6 student mentors 2005-2006 Marco Russo 2004-2005 Kimberley Zamor 2004-2005 Mahesh Polavarapu Summer 2004 USS workshop: 14 incoming freshmen and 6 student mentors 2003-2006 Joseph Hoover 2003-2004 Sharon Calderwood 2003-2004 Audrey Thompson 2003-2004 Desma Mitchell Summer 2003 USS workshop: 12 incoming freshmen and 2 student mentors 2001-2002 Laura Meints

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2001-2003 Jennifer VanOverbeke 2001 Khadijah Breathett 2000-2001 Maggie Overbey 2000-2002 Jovana Grbic, B. S. with honors 2000-2003 Adam Tenderholt 2000 Kari Riggs, B.A. 1999-2001 Doug Fowler, B.S. with honors 1999 David Gamboa, B.S. 1999-2000 Jaime Royal 1999-2001 Nathan Shepherd, B.S. with honors 1999 Ben Staehlin, B.S. 1998-1999 Anne Reynolds, B,S. with honors 1998-1999 Eric Roeland, B.A. 1998-1999 Jeffrey Wang , B.S. with honors 1997 Ghenet Simpson, B.S. 1996-1998 Arlene Molino, B.S. with honors 1996-1998 Sidharth Padia, B.S. with honors

PH.D. THESES SUPERVISED 1. Ricardo Alarcon Garcia “Calcium Activation Mechanisms of Synaptotagmins I and II” Ph.D. Northwestern University, 2001. 2. John Carroll Payne, “Spectroscopic Analysis of the Interactions Between Lead and Structural Zinc-Binding Domains” Ph.D. Northwestern University, 2002. 3. Bernd U. Sehgal “Interactions of EF-hand and C2 Proteins With Calcium and Lead” Ph.D. Northwestern University, 2002. 4. Sandhya Deo “Investigations Into the Molecular Mechanisms of Lead Toxicity: Pb2+ Sensors and the Effects of Pb2+ on Gene Expression” Ph.D. Northwestern University, 2002. 5. John Stedman Magyar “Study of Coordination Chemistry, Thermodynamics, and Kinetics of Metal Binding to Zinc-Binding Peptides” Ph.D. Northwestern University, 2002. 6. Amy Ghering “Spectroscopic Determination of the Thermodynamics of Lead, Zinc, and Cobalt Interactions with GATA Proteins” Ph.D. Northwestern University, 2003. 7. Brian Rous “Spectroscopic Determination of the Thermodynamics of Lead, Zinc, and Cobalt Interactions with Glucocorticoid Receptor” Ph.D. Northwestern University, 2003. 8. Ryan Andersen “Inorganic Biochemistry of C2-Containing Calcium-Binding Proteins and Small-Molecule Lead Compounds with Mixed Nitrogen-Sulfur Coordination” Ph.D. Northwestern University, 2004. 9. Elizabeth Suarez “Spectroscopic and Thermodynamic Investigations of Pb2+ EDTA Amide Analogs in an Aqueous Environment and Studies of Pb2+ Localization in S. cerevisiae by Confocal Fluorescence Microscopy”, Ph.D. Northwestern University, 2006.

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GRADUATE COMMITTEES (NOT RESEARCH ADVISOR) AT UCLA: 2007-present Demian Willette, Environmental Health Sciences 2007-present Steven Karpowicz, Chemistry 2007-present Kevin Sea, Chemistry 2007-present Lindsay Kane, Chemistry 2007 David Kimbrough, Environmental Health Sciences

GRADUATE COMMITTEES (NOT RESEARCH ADVISOR) AT NORTHWESTERN UNIVERSITY: 2006 Rebecca Copeland, Chemistry 2005-2006 Yoriel Marcano, Chemistry 2005-2006 Monica Canalizo, Chemistry 2005-2006 Meera Raja, Chemistry 2004 Chris Singer, Ph.D. Chemistry 2004-2006 Ian Saratovsky, Chemistry 2004 Laura Lemmers, Chemistry 2004-2006 Hamsell Alvarez, Chemistry 2003-2006 Jody Major, Chemistry 2003-2006 Korin Wheeler, Chemistry 2003-2006 Chandra Ranjit Yonzon, Chemistry 2002-2006 Yi Xue, Chemistry 2002-2006 Carnie Abajan, Chemistry 2002-2005 Jodi O’Donnell, Ph.D. Chemistry 2002-2005 Rebecca Landry, Ph.D. Chemistry 2002-2006 Eric Kawamoto, Chemistry 2002-2005 Hogbo Li, Ph.D. Chemistry 2002-2006 Jiang Yao, Chemistry 2001-2002 Eileen Bayer, IBiS 2001-2005 Kristi Calvert, Chemistry 2001-2005 Martin Masar, Chemistry 2000-2005 Lydia Finney, Ph.D. Chemistry 2000-2004 Amy Wernimont, IBiS 1999-2002 Joanna Miller, IBiS 1999-2002 Adam Eisenberg, Chemistry 1999-2001 Matthew Metz, Chemistry 1998-2001 Michael Douglass, Ph.D., Chemistry 1998-2000 Craig McLaughlan, Ph.D., Chemistry 1998-2000 Michael Schwartz, Ph.D., IBiS 1997-2001 Paul Gene, Ph.D., Chemistry 1997-2001 Caryn Outten, Ph.D., Chemistry 1997 Bo Yang, M.S. Chemistry 1997-2000 James Storhoff, Ph.D., Chemistry 1996-2000 Wade K. Jarrell, Ph.D., Chemistry

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