Nether Alderley Looking Forward Alderley Park Development Survey
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Information About the Alderley Unit
If you require translation services or a copy of this document in other languages, audio tape, Braille or larger print, please speak to a member of CWP staff, e-mail [email protected] or write to: Communications, Chesh- ire and Wirral Partnership NHS Foundation Trust, Upton Lea, Countess of Chester Health Park, Liverpool Road, Chester, CH2 1BQ. Information about the Alderley Unit Information for patients, carers and families Jeśli wymagane jest tłumaczenie lub kopia niniejszego dokumentu w innych językach, na taśmie magnetofonowej, w języku Braille’a lub dużym drukiem, prosimy o skontaktowanie się z członkiem personelu CWP (Organizacja partnerska krajowego systemu zdrowia regionów Cheshire i Wirral) lub przez pocztę elektroniczną: [email protected] lub na adres: Communications, Cheshire and Wirral Partnership NHS Foundation Trust, Upton Lea, Countess of Chester Health Park, Liverpool Road, Chester, CH2 1BQ. Os oes arnoch angen gwasanaeth cyfiethu neu gopi o'r ddogfen hon mewn ieithoedd eraill, tâp sain, Braille neu brint mawr, siaradwch ag aelod o staff CWP, e-bost [email protected] neu ysgrifennwch i: Communica- tions, Cheshire and Wirral Partnership NHS Foundation Trust, Upton Lea, Countess of Chester Health Park, Liverpool Road, Chester, CH2 1BQ. For more information see www.cwp.nhs.uk. © CWP NHS FoundationTrust The information in this leaflet was valid at the date of production June 2015 and is due for review in June 2017 Leaflet code: E/MD/05-001 12 Introduction Useful contact numbers The Alderley Unit is a regional Alderley Unit 01625 862500 Low Secure Unit for people with learning disabilities who have Social Services 0300 123 5010 committed an offence or are assessed as likely to commit an Benefit Advice Line 0800 88 22 00 offence. -
Alderley Park the Future As a World-Class Life Science Facility Planning Application Summary Document
DECEMBER 2015 ALDERLEY PARK THE FUTURE AS A WORLD-CLASS LIFE SCIENCE FACILITY PLANNING APPLICATION SUMMARY DOCUMENT Alderley Park is a world-class Life Science research and development (R&D) facility. The site currently houses around 190,000 sq m of premier scientific laboratory space, offices, restaurants, cafes, conferencing space and energy plant, set in 400 acres of parkland. As a centre for scientific research, it is one of the few facilities in the country with a comprehensive offering to support drug discovery and development. It was AstraZeneca’s global lead centre for cancer research, employing at its peak up to 10,000 people in highly skilled jobs. These facilities at Alderley Park are high-quality A planning application has been submitted to and high-tech, and require significant ongoing Cheshire East Council for future development investment to retain them. £550 million has been at Alderley Park. The planning application invested in Alderley Park since 1997 and further, has been allocated the reference number major investment is required to repurpose the site 15/5401M. from single to multi-occupier use, maintain the facilities and cover ongoing overheads. This summary document sets out the key elements of the proposals. ILLUSTRATIVE MASTERPLAN SIGNIFICANT INVESTMENT PROPOSED OVER THE NEXT 10 YEARS In March 2013, AstraZeneca announced The site was purchased by Bruntwood/MSP, its decision to relocate its R&D facilities to part of Alderley Park Ltd who now wish to Cambridge, leading to uncertainty over the secure the future of the site, retaining talent and future of Alderley Park and its role in the local jobs, by taking forward the Taskforce’s vision. -
Mottram St. Andrew Parish Council
Edward Charles Slater 05.06.1887 – 15.12.1917 Edward Charles Slater was baptised on the 5th June 1887 in Alderley Edge, the son of John and Mary Slater. In the 1881 census Edward was living in Welsh Row, Alderley Edge with his parents and his brother John and sisters Harriet and Emily. By 1901 the family had moved to Nether Alderley. By 1911 Edward had left home and was living with his wife Alice in Oak Road, Mottram St. Andrew who he had married in 1909 at All Saints Church, Siddington. Alice’s maiden name was Coppock and Edward’s occupation was a bricklayer. They had five children. Edward, Frank, Joey, Wallace Charles and Ellen. They also had a foster child named George. Edward was baptised in Prestbury in 1911, Joey in 1912, Frank in 1914, Wallace Charles in 1917 and Ellen in 1920. Edward enlisted in Mottram St. Andrew and served as gunner in the Royal Garrison Artillery (RGA) in the 63rd Siege Battery in France and Flanders and he was awarded the Victory Medal and the British Medal. His army number was 171714. Siege Batteries were equipped with heavy howitzers sending large calibre high explosive shells in high trajectory, plunging fire. The usual armaments were 6inch, 8inch or 9.2inch howitzers, although some had large rail or road mounted 12inch howitzers. The 63rd Siege Battery had two rail mounted 12inch howitzers and were sent to France on the 2nd March 1916. As British artillery tactics developed the Siege Batteries were most often employed in destroying or neutralising the enemy artillery as well as putting destructive fire down on strong points, dumps, stores, roads and railways behind enemy lines. -
Novel Neutralizing Hedgehog Antibody MEDI-5304 Exhibits Antitumor Activity by Inhibiting
Author Manuscript Published OnlineFirst on December 16, 2013; DOI: 10.1158/1535-7163.MCT-13-0420 Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Fully Human Anti-Hedgehog Antibodies Novel neutralizing hedgehog antibody MEDI-5304 exhibits antitumor activity by inhibiting paracrine hedgehog signaling. Authors: Neil R. Michaud1*, Youzhen Wang1, Kristen McEachern1, Jerold J. Jordan1, Anne Marie Mazzola1, Axel Hernandez1, Sanjoo Jalla2, Jon W. Chesebrough2, Mark J. Hynes3, Matthew Belmonte 1, Lidong Wang3, Jaspal S. Kang4#, Jelena Jovanović5, Naomi Laing1, David W. Jenkins1, Elaine Hurt2, Meina Liang6, Christopher Frantz7, Robert E. Hollingsworth2, Diane M. Simeone3, David C. Blakey8, and Vahe Bedian1* Authors’ affiliation: 1Oncology iMED, AstraZeneca-R&D Boston, Waltham, MA 2Oncology Research, MedImmune LLC, Gaithersburg, MD 3Translational Oncology Program, University of Michigan, Ann Arbor, MI; 4Amgen British Columbia, Burnaby, BC, Canada 5Lead Generation- Research, Medimmune LLC, Granta Park, Cambridge, UK 6Clinical Pharmacology and DMPK, MedImmune LLC, Hayward, CA 7Biologics Safety Assessment, MedImmune LLC, Mountain View, CA 8Oncology iMed, AstraZeneca, Alderley Park, Macclesfield. UK #Current address: Paul Kang, CSO, Innovative Targeting Solutions Inc., Burnaby BC, Canada *corresponding authors: Neil R. Michaud, Ph.D. Oncology iMED AstraZeneca-R&D Boston Waltham, MA 02451 e-mail: [email protected] Vahe Bedian Ph.D. Oncology iMED AstraZeneca-R&D Boston Waltham, MA 02451 phone:781-839-4613 e-mail: [email protected] Running title: Fully Human Anti-Hedgehog Antibodies Key Words: Hedgehog, Antibody, Xenograft, XenoMouse, cancer stem cells Grant Support: This work was funded by AstraZeneca PLC and MedImmune LLC. Disclosure of Potential Conflicts of Interest: There are no potential conflicts of interest. -
1 the Cottage, Welsh Row, Nether Alderley, SK10
1 The Cottage, Welsh Row, Nether Alderley , SK10 4TY www.michaeljchapman.co.uk A tw o bedroom period cottage with two reception rooms and a kitchen breakfast room with views over the open countryside to the front and rear. Available now part furnished. The accommodation in brief comprises of:- Porch, sitting room, dining room, kitchen breakfast room with fitted appliances, cloakroom & downstairs wc. To the first floor there is a master bedroom with built in wardrobes, a se cond bedroom with dressing/bed area and a family bathroom. Externally there is a shared garden with the next door property and off road parking. LOCATION: Alderley Edge village centre offers a wide range of high quality shops suitable for most day to day requirements and the area also boasts a good range of social and recreational facilities. Good local schools cater for children of all ages. Ideal for the commuter, the areas are especially well placed for easy access to the business centres of Manchester and Stockport. Alderley Edge station offers a fast electric commuter service and there are Inter-city links available at nearby Wilmslow. For the motorway traveller the M56 is available at Ringway or the M6 at Holmes Chapel. Alternatively the new A34 by- pass road provide easy access to the superstores of Marks and Spencer, Tesco and a little further on, John Lewis and Sainsbury’s. Manchester International Airport is only a short drive away. DIRECTIONS: From our office turn left onto London Road which turns into Congleton Road. Stay on here for approximately one mile before turning right at the Alderley Cross. -
Counciltaxbase201819appendix , Item 47
APPENDIX A COUNCIL TAX - TAXBASE 2018/19 COUNCIL TAX - TAXBASE 2018/19 BAND D TAX BASE BAND D TAX BASE CHESHIRE EAST EQUIVALENTS 99.00% CHESHIRE EAST EQUIVALENTS 99.00% Acton 163.82 162.18 Kettleshulme 166.87 165.20 Adlington 613.67 607.53 Knutsford 5,813.84 5,755.70 Agden 72.04 71.32 Lea 20.78 20.57 Alderley Edge 2,699.00 2,672.01 Leighton 1,770.68 1,752.97 Alpraham 195.94 193.98 Little Bollington 88.34 87.45 Alsager 4,498.81 4,453.82 Little Warford 37.82 37.44 Arclid 154.71 153.17 Lower Peover 75.81 75.05 Ashley 164.05 162.41 Lower Withington 308.54 305.45 Aston by Budworth 181.97 180.15 Lyme Handley 74.74 74.00 Aston-juxta-Mondrum 89.56 88.66 Macclesfield 18,407.42 18,223.35 Audlem 937.36 927.98 Macclesfield Forest/Wildboarclough 112.25 111.13 Austerson 49.34 48.85 Marbury-cum-Quoisley 128.25 126.97 Baddiley 129.37 128.07 Marton 113.19 112.06 Baddington 61.63 61.02 Mere 445.42 440.96 Barthomley 98.14 97.16 Middlewich 4,887.05 4,838.18 Basford 92.23 91.31 Millington 101.43 100.42 Batherton 24.47 24.23 Minshull Vernon 149.65 148.16 Betchton 277.16 274.39 Mobberley 1,458.35 1,443.77 Bickerton 125.31 124.05 Moston 277.53 274.76 Blakenhall 70.16 69.46 Mottram St Andrew 416.18 412.02 Bollington 3,159.33 3,127.74 Nantwich 5,345.68 5,292.23 Bosley 208.63 206.54 Nether Alderley 386.48 382.61 Bradwall 85.68 84.82 Newbold Astbury-cum-Moreton 374.85 371.10 Brereton 650.89 644.38 Newhall 413.32 409.18 Bridgemere 66.74 66.07 Norbury 104.94 103.89 Brindley 73.30 72.56 North Rode 125.29 124.04 Broomhall 87.47 86.59 Odd Rode 1,995.13 1,975.18 Buerton -
Hand-List of the Legh of Booths Charters in the John Rylands Library
HAND-LIST OF THE LEGH OF BOOTHS CHARTERS IN THE JOHN RYLANDS LIBRARY. BY F. TAYLOR, M.A., PH.D. KEEPER OF MANUSCRIPTS AND ASSISTANT LIBRARIAN IN THE JOHN RYLANDS LIBRARY. documents listed below relate to the old Cheshire A family of Legh of Norbury Booths Hall, near Knutsford, and its estates from the late thirteenth to the early nineteenth century. They were saved from destruction 1 last century by the antiquary Richard Henry Wood (1820-1908), a scholar associated for many years with local history studies in Cheshire and Lancashire, and now form part of the large and important manuscript collection which he brought together from many sources. A general survey of this collection, which was deposited in the Library in 1940 by Captain J. Hatton Wood, has been given elsewhere,2 and it is perhaps sufficient here to notice that, in addition to the Legh charters, it is rich in monastic documents (twelfth-fifteenth century) and rare seals,3 and contains several royal grants (the earliest dating from the reign of Henry I), as well as a considerable number of miscellaneous deeds, mostly pre-1500, relating to some twenty-five counties. The Cheshire element of the Hatton Wood MSS., excluding the Legh charters, is comparatively small, numbering only thirty-six documents. Certain of these, however, are worthy of note, among them being eight thirteenth-century charters of the Abbey of St. Werburgh, Chester, five leases (1562-1647) from the Master and Brethren of the Hospital of St. John without the North Gate, Chester, a letter from Burghley to Edmund Gammell, late Mayor of Chester (Oct. -
Cycle of Prayer
Cycle of Prayer 08 September 2019 - 11 January 2020 Diocese of Chester Key: C = Clergy LM = Licensed Lay Minister (Reader) (Pastoral Worker) (Youth Worker) Diocesan entries from the Anglican Cycle of Prayer are in italics. Chester Diocesan Board of Finance. Church House, 5500 Daresbury Park, Daresbury, Warrington WA4 4GE. Tel: 01928 718834 Chester Diocesan Board of Finance is a company limited by guarantee registered in England (no. 7826) Registered charity (no. 248968) Foreword I’ll never forget, after a long walk with my Dad, in Pendle, Lancashire, sipping a pint in a pub and chatting to the locals. Five minutes later I was surprised to turn to see my Dad placing his arthritic hand into the dirty palms of a particularly burly local farmer as they bowed their heads in prayer. I didn’t quite know where to look or what to do, so I lowered my head and kept quiet. It seemed like the right thing to do, and it helped me avoid the gaze of the growing number of amused boozy onlookers. That was my first and slightly embarrassing introduction to prayer. Since then I’ve travelled a long way, but I still remember the first tentative steps I took for myself. I also remember just how uncomfortable and alien praying felt to me. For those well versed in the lifelong discipline of prayer, it can perhaps be easy to forget just how strange the whole thing can be to start. I am grateful to one good colleague from many years ago who shared with me the William Temple quote: ‘When I pray, coincidences happen, when I don’t they don’t.’ As you pray during this period, please pray for those who are just starting and giving it a go. -
6Th Annual Translational Medicine Conference City Hotel, Derry/Londonderry, Northern Ireland 25Th - 26Th Sept 2014
6th Annual Translational Medicine Conference ‘Personalising Health and Care’ Date: 25th and 26th September 2014 | Venue: City Hotel, Derry/Londonderry, N.Ireland, UK 1 6th Annual Translational Medicine Conference City Hotel, Derry/Londonderry, Northern Ireland 25th - 26th Sept 2014 Conference Sponsors 2 6th Annual Translational Medicine Conference City Hotel, Derry/Londonderry, Northern Ireland 25th - 26th Sept 2014 Contents Page Conference Programme .................................................................................... 4 Biographies .......................................................................................................... 6 - 9 Delegate List ........................................................................................................ 10 - 12 Bio-Entrepreneur Programme........................................................................ 13 About C-TRIC ....................................................................................................... 14 - 15 Abstracts Poster Presentations................................................................. 16 - 42 Abstracts Oral Presentations................................................................. 43 Abstracts Poster List................................................................. 44 3 6th Annual Translational Medicine Conference City Hotel, Derry/Londonderry, Northern Ireland 25th - 26th Sept 2014 ‘Personalising Health and Care’ - Conference Programme Day One Thursday 25th Sept 1:00 pm Registration and Tea/Coffee 4.30 pm Oral -
Alderley Park Development Framework
Alderley Park Development Framework Consultation Draft - January 2015 0i 2 Contents 1 Introduction 2 The Site 3 Planning Policy 4 Design Guidance 5 Indicative Masterplan 6 Planning Applications 7 Summary and Next Steps Appendices 3 1 Introduction Alderley Park, a research and development site The Taskforce commissioned a study to establish the new vision for the site. It allocates Alderley Park as an renowned for the discovery and development of potential future demand from the life science sector, for ‘opportunity site’, seeking to promote and encourage the innovative new medicines, is a key part of the North the world class laboratory and office space on site1. That development of the Life Science Park whilst recognising West Life Science Ecosystem. Opening more than 40 study indicated that whilst there would not by any means that there is likely to be a need for a degree of flexibility years ago, the site has a rich heritage of important be an instant demand for all the site’s facilities, with an regarding land uses to deliver, grow and sustain the Life advancements in medical treatments, including a appropriate business model, there is potential to build on Science Park vision. number of anti-cancer treatments. As the lead centre the BioHub concept, repurposing the site to offer facilities Until the adoption of the CELPS, the current development for cancer research, Alderley Park currently houses which complement existing life science resources across plan for the area remains the Macclesfield Borough the global Advanced Lead Discovery Centre, and its the region, such that Alderley Park can continue to be a Local Plan. -
ANNEX Analysis of School Places 2011 Introduction
ANNEX Analysis of School Places 2011 Introduction The Borough of Cheshire East is divided into 7 Local Area Partnerships (LAPs). These are Congleton, Crewe, Knutsford, Macclesfield, Nantwich, Poynton and Wilmslow. In order that the Local Authority meets its statutory duty to ensure there are sufficient school places within its area for its residents, ongoing analysis of provision and consultation on changes will be driven by school census data at LAP level. LAPs facilitate local consultation and engagement to gain a shared understanding of local issues, needs and preferences important to the area. This report presents information about the number of pupil places provided in Cheshire East Council’s publicly funded schools, which includes Academies and Free Schools, together with information about the number of pupils on roll in each school and the number of vacant school places. Any increase in demand for school places arising as a consequence of new housing developments is in addition to the core analysis of demographic basic need as set out in this document and is investigated separately. Planning applications are subject to a Section 106 Agreement, which will identify the potential number of pupils that the proposed housing development would yield. Financial contributions will be sought from developers to enable the Local Authority to commission sufficient school places to meet the additional future demand directly related to growth in pupil numbers from new housing. Information published by the Office for National Statistics (2012) shows that previous projections for population growth, which were based on 2009 mid-year estimates, were underestimated and revised forecasts now show that by 2020 there will be around 21% more primary aged children than in 2010. -
854 Far Che~Hire
854 FAR CHE~HIRE. FARMERS-continued. Jackson T. Illage grn.Brereton,Sndbch Johnson James, lladdiley cottage-,. Bad... Hyde By. Mill lane, Bredbury,Stckpt Jackson T.Old wood,Baguly . .Altrnchm diley, Nantwich Hyde John, Ridge end,Marple,Stckprt Jackson Thos. .Alpraham, Tarporley Johnson Jas . .Arth. Calveley,Ta.rJ?Orley Hyde Wm. Cop Brow, Gee Cross, Hyde Jackson Thomas, .Ashley, .Altrincham Johnson John, Birch heath, 'Jii~erton,. Hyde William, Hattersley, Manchester Jacksun Thomas, Hampton green, Tarporley Hyde Wm. High Lee, Sutton, Mcclsfid Hampton, Malpns Johnson John, Budwortru aommon,. Ikin John, Egerton green, Egerton, Jackson Thomas, Swanlow lane, Over, Little Bud worth, Tarporley Malpas Winsford R.S.O Johnson John, Bunbury, Tarporley Ikin Samuel, Barton, Malpas Jackson W . .Aston-by-Budworth,Nthwch Johnson John, Burton, Chester Ingham Wm. lly. Sutton, Macclesfield Jackson William, Handley, Chester Johnson John, Etchells, Cheadle Ithell James, \Vervin, Chester Jackson Wm. Nether .Alderley, Crewe Johnson John, Moston, Sandbach Ithell Richd. Old hall, Upton, Chester Jackson William, Oak lanes, Church Johnson John, SpurshJw, Tarporley Jackson Herbert & •Stephen, Clay la. Minshull, Middlewich Jo~n-sol1! Joseph, Hig-her Heyes, Kings- TimpeTley, .Altrincham Jackson William, Shrigley road, Bol- ley, Warringwn Jackson Herbert & Stephen, Roaring lington, Macclesti.eld Johnson Joseph, Warmingbam,Sndbcb. gate, Hale, .Altrinchnm Jackson Wm. Timperley, .Altrincham Johnson Mri-1. M. Willington, CbJester J ackson Mrs . .Alice, Clotton-Hoofield, J ackson William, Whitegate house, J ohnson Mrs. Maria, Stapeley, Nntwch Tarporley Sound, NantwiC'h Johnson Mr'S. M. Eddisbnry,Northwicb. Jucksun Mrs . .A. Birch Heath road, Jackson W.jn.Brink, Harrop, Mcclsfld Johnsou. Mrs. :Mary, Springs Lane hall"' Tarporley Jackson Wm.