Contributors

Ryan Lloyd Albritton, MD Robert S. Langer, ScD Resident Physician Institute Professor Diagnostic Radiology Resident Department of Chemical Engineering Department of Radiology Massachusetts Institute of Technology UCSF Medical Center Cambridge, MA University of California, San Francisco San Francisco, CA Stephen C. Lazarus, MD Professor of Medicine Seth L. Alper, MD, PhD Department of Pulmonary & Critical Care Medicine Professor of Medicine, Harvard Medical School University of California, San Francisco Associate Physician, Department of Medicine San Francisco, CA Beth Israel Deaconess Medical Center Boston, MA Benjamin Leader, MD, PhD Senior Resident Physician April W. Armstrong, MD Department of Emergency Medicine Clinical Fellow Brown University Medical School Harvard Combined Dermatology Program, Harvard Medical Rhode Island Hospital School Providence, RI Department of Dermatology, Massachusetts General Hospital David C. Lewis, MD Boston, MA Donald G. Millar Distinguished Professor of Alcohol and Addiction Studies Ehrin J. Armstrong, MD, MSc Community Health and Medicine Clinical Fellow Center for Alcohol & Addiction Studies Department of Medicine Brown University Massachusetts General Hospital Providence, RI Boston, MA Allen Shuyuan Liu, MD Sarah R. Armstrong, MS, DABT Surgical Resident Senior Scientist Department of Surgery Cambridge Environmental Inc. Brigham and Women’s Hospital Cambridge, MA Boston, MA

Ramy A. Arnaout, DPhil, MD Eng H. Lo, PhD Clinical Fellow in Pathology Professor, Radiology and Neurology Department of Pathology Harvard Medical School Brigham and Women’s Hospital Director, Neuroprotection Research Laboratory Boston, MA Departments of Neurology and Radiology Program for Evolutionary Dynamics Massachusetts General Hospital Harvard University Boston, MA Cambridge, MA Daniel H. Lowenstein, MD Alireza Atri, MD, PhD Professor of Neurology Instructor in Neurology Director, UCSF Epilepsy Center Harvard Medical School Department of Neurology Assistant in Neurology University of California, San Francisco Department of Neurology San Francisco, CA Massachusetts General Hospital Boston, MA Thomas Michel, MD, PhD Professor of Medicine (Biochemistry), Harvard Medical Jerry Avorn, MD School Professor of Medicine, Harvard Medical School Senior Physician, Cardiovascular Division, Brigham and Senior Physician and Chief, Division of Women’s Hospital Pharmacoepidemiology and Pharmacogenomics Boston, MA Brigham and Women’s Hospital Boston, MA Keith W. Miller, MA, DPhil

Edward Mallinckrodt Professor of Pharmacology David A. Barbie, MD Department of Biological Chemistry and Molecular Chief Resident in Internal Medicine Pharmacology Department of Medicine Harvard Medical School Massachusetts General Hospital Pharmacologist Instructor in Medicine Department of Anesthesia and Critical Care Harvard Medical School Massachusetts General Hospital Boston, MA Boston, MA

Robert L. Barbieri, MD Joshua D. Moss, MD Kate Macy Ladd Professor of Obstetrics, Gynecology and Fellow Reproductive Biology Cardiovascular Division Department of Obstetrics, Gynecology and Reproductive Hospital of the University of Pennsylvania Biology Philadelphia, PA Harvard Medical School Chairman Martin G. Myers, Jr., MD, PhD Department of Obstetrics and Gynecology Associate Professor of Medicine Brigham and Women’s Hospital Division of Metabolism, Endocrinology and Diabetes Boston, MA University of Michigan Medical School Ann Arbor, MI Mallar Bhattacharya, MD, MSc Senior Resident Mireya Nadal-Vicens, MD, PhD Department of Medicine Resident Tutor in Medicine Johns Hopkins Hospital Mather House Johns Hopkins University Harvard University Baltimore, MD Cambridge, MA Child and Adolescent Psychiatry Fellow Christopher W. Cairo, Ph.D. Department of Child and Adolescent Psychiatry Assistant Professor Massachusetts General Hospital Department of Chemistry Boston, MA University of Alberta Edmonton, AB Canada Dalia Shoretz Nagel, MD Resident Michael S. Chang, MD Department of Ophthalmology Department of Orthopaedic Surgery The Mount Sinai School of Medicine University of Iowa Hospitals and Clinics New York, NY Iowa City, IA Thomas P. Rocco, MD William W. Chin, MD Associate Professor of Medicine, Harvard Medical School Vice President Cardiovascular Division, Brigham and Women’s Hospital Discovery Research and Clinical Investigation Boston, MA Eli Lilly & Company Associate Chief, Cardiology Section, VA Boston Healthcare Volunteer Professor of Medicine System Department of Medicine West Roxbury, MA Indiana University School of Medicine Indianapolis, IN Harris S. Rose, MD Resident Deborah Yeh Chong, MD Department of Orthopaedic Surgery Ophthalmology Resident University of Texas Health Science Center - Houston Kellogg Eye Center Houston, TX University of Michigan Ann Arbor, MI Edward T. Ryan, MD Assistant Professor of Medicine, Harvard Medical School Janet Chou, MD Director, Tropical and Geographic Medicine Center, Division Clinical Fellow of Infectious Diseases, Massachusetts General Hospital Department of Pediatrics, Harvard Medical School Boston, MA Resident Department of Pediatric Medicine, Children’s Hospital Marvin Ryou, MD Boston Clinical & Research Fellow

Boston, MA Division of Gastroenterology Brigham and Women’s Hospital Vinh Quoc Chung, MD, MPharmSci, MTh Boston, MA Dermatology Resident Department of Dermatology Joshua M. Schulman Emory University Harvard Medical School Atlanta, GA Boston, MA

Jay Hwan Chyung, MD, PhD Charles N. Serhan, PhD Consultant Simon Gelman Professor of Anesthesia (Biological Boston Consulting Group Chemistry and Molecular Pharmacology), Harvard Boston, MA Medical School Director, Center for Experimental Therapeutics and David E. Clapham, MD, PhD Reperfusion Injury Aldo R. Castañeda Professor of Cardiovascular Research Department of Anesthesiology, Perioperative and Pain Director of Cardiovascular Research Medicine Professor of Pediatrics, Children’s Hospital Boston Brigham and Women’s Hospital Professor of Neurobiology, Harvard Medical School Boston, MA Boston, MA Helen M. Shields, MD Donald M. Coen, PhD Associate Professor, Harvard Medical School Professor of Biological Chemistry and Molecular Physician, Department of Medicine Pharmacology Beth Israel Deaconess Medical Center Harvard Medical School Boston, MA Boston, MA Steven E. Shoelson, MD, PhD David E. Cohen, MD, PhD Professor, Department of Medicine, Harvard Medical School Associate Professor, Harvard Medical School Associate Director, Research Division, Joslin Diabetes Director of Hepatology Center Department of Medicine, Brigham and Women’s Hospital Boston, MA Boston, MA Aimee D. Shu, MD John P. Dekker, PhD Clinical Fellow MD-PhD Student Division of Endocrinology Department of Neurobiology Department of Medicine Harvard Medical School Columbia University Medical Center Boston, MA New York, NY

George D. Demetri, MD Josef B. Simon, MD Associate Professor of Medicine, Harvard Medical School Resident Director, Center for Sarcoma and Bone Oncology Orthopedic Surgery Department of Medical Oncology Harvard Medical School Dana-Farber Cancer Institute Massachusetts General Hospital Boston, MA Boston, MA

Robert G. Dluhy, MD David G. Standaert, MD, PhD Professor of Medicine, Harvard Medical School Professor Senior Physician Department of Neurology Department of Medicine University of Alabama at Birmingham Brigham and Women’s Hospital Birmingham, AL Boston, MA Gary R. Strichartz, PhD David M. Dudzinski, MD, JD Professor of Anaesthesia, Harvard Medical School Clinical Fellow in Internal Medicine Director, Pain Research Center Department of Medicine Department of Anesthesiology, Perioperative and Pain Harvard Medical School Medicine Massachusetts General Hospital Brigham and Women’s Hospital Boston, MA Boston, MA

Stuart A. Forman, MD, PhD Robert M. Swift, MD, PhD Associate Professor of Anaesthesiology Professor Department of Anaesthesiology, Harvard Medical School Department of Psychiatry & Human Behavior Associate Anesthetist Center for Alcohol & Addiction Studies Department of Anesthesia & Critical Care Brown University Massachusetts General Hospital Associate Chief of Staff for Research Boston, MA Providence Veterans Administration Medical Center Providence, RI David A. Frank, MD, PhD Assistant Professor of Medicine, Harvard Medical School Cullen Taniguchi, MD, PhD Assistant Professor, Department of Medical Oncology Postdoctoral Fellow Dana-Farber Cancer Institute Molecular and Cellular Physiology Boston, MA Joslin Diabetes Center Harvard Medical School Joshua M. Galanter, MD Boston, MA Fellow Pulmonary and Critical Care Medicine Armen H. Tashjian, Jr., MD University of California, San Francisco Professor of Biological Chemistry and Molecular San Francisco, CA Pharmacology, emeritus Harvard Medical School David E. Golan, MD, PhD Professor of Toxicology, emeritus Professor of Biological Chemistry and Molecular Harvard School of Public Health Pharmacology, Professor of Medicine, Harvard Medical Department of Genetics and Complex Diseases School Harvard School of Public Health Scholar and Founding Member, The Academy at Harvard Boston, MA Medical School Physician, Hematology Division, Brigham and Women’s Charles Russell Taylor, MD Hospital and Dana-Farber Cancer Institute Associate Professor Department of Biological Chemistry and Molecular Department of Dermatology Pharmacology, Department of Medicine Harvard Medical School Harvard Medical School Director of Phototherapy; Staff Dermatologist Boston, MA Department of Dermatology Massachusetts General Hospital Laura C. Green, PhD, DABT Boston, MA Senior Scientist and President Cambridge Environmental Inc. Timothy John Turner, PhD Cambridge, MA Assistant Research Professor Lecturer Department of Neuroscience Biological Engineering Division Tufts University School of Medicine Massachusetts Institute of Technology Boston, MA Cambridge, MA *Michael Tsan Ty, MD, MS Edmund A. Griffin, Jr., MD, PhD Clinical Fellow in Neurology Resident Physician Massachusetts General Hospital/Brigham and Women’s Department of Psychiatry Hospital Neurology Program Columbia University Boston, MA New York State Psychiatric Institute New York, NY John L. Vahle, DVM, PhD Senior Research Advisor Robert S. Griffin, PhD Pathology and Toxicology MD-PhD Program Lilly Research Laboratories Harvard Medical School Greenfield, IN Boston, MA Andrew J. Wagner, MD, PhD F. Peter Guengerich, PhD Instructor of Medicine Professor Harvard Medical School Department of Biochemistry Department of Medical Oncology Vanderbilt University School of Medicine Dana-Farber Cancer Institute Nashville, TN Boston, MA

Heidi Harbison, MD Liewei Wang, MD, PhD Emergency Medicine Resident Assistant Professor Brigham and Women’s Hospital Department of Molecular Pharmacology and Experimental Boston, MA Therapeutics Mayo Clinic College of Medicine David C. Hooper, MD Associate Consultant Associate Professor of Medicine, Harvard Medical School Department of Molecular Pharmacology and Experimental Associate Chief Therapeutics Division of Infectious Diseases Mayo Clinic Massachusetts General Hospital Rochester, MN Boston, MA Richard M. Weinshilboum, MD Louise Ivers, MD, MPH, DTM&H Professor Instructor in Medicine, Department of Medicine Department of Molecular Pharmacology and Experimental Harvard Medical School Therapeutics Associate Physician Mayo Clinic College of Medicine Department of Medicine Consultant Brigham and Women’s Hospital Department of Molecular Pharmacology and Experimental Boston, MA Therapeutics Mayo Clinic Anne G. Kasmar, MD, MSc Rochester, MN Research Fellow Combined MGH-BWH Program in Infectious Diseases *Ariel Weissmann, MD, MPH Harvard Medical School Resident in Internal Medicine Fellow Boston Medical Center Department of Infectious Diseases Boston, MA Massachusetts General Hospital Boston, MA Freddie M. Williams, MD Fellow Lloyd B. Klickstein, MD, PhD Cardiovascular Division Translational Medicine Head University of Virginia Musculoskeletal Diseases Charlottesville, VA Novartis Institutes for Biomedical Research Cambridge, MA Clifford J. Woolf, MD, PhD Associate Physician Richard J. Kitz Professor of Anesthesia Research, Harvard Division of Rheumatology, Immunology & Allergy Medical School Brigham and Women’s Hospital Director, Neural Plasticity Research Group, Department of Boston, MA Anesthesia and Critical Care Massachusetts General Hospital Joseph C. Kvedar, MD Boston, MA Associate Professor Department of Dermatology Jacob Wouden, MD Harvard Medical School Clinical Fellow Vice Chairman & Residency Program Director Department of Radiology Department of Dermatology Harvard Medical School Massachusetts General Hospital Resident Boston, MA Department of Radiology Brigham and Women’s Hospital John C. LaMattina, MD Boston, MA Surgical Resident Department of Surgery Robert W. Yeh, MD, MBA, MSc Massachusetts General Hospital Cardiology Fellow Boston, MA Cardiology Division Department of Medicine University of California, San Francisco San Francisco, CA

*deceased