Anti-CMPK2 (C-terminal) polyclonal antibody (DPABH-02072) This product is for research use only and is not intended for diagnostic use.
PRODUCT INFORMATION
Antigen Description May participate in dUTP and dCTP synthesis in mitochondria. Is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor. Efficacy is highest for dUMP followed by dCMP; CMP and UMP are poor substrates. May be involved in mtDNA depletion caused by long term treatment with ddC or other pyrimidine analogs.
Immunogen Synthetic peptide corresponding to 19 amino acid residues near the carboxy terminus of Human CMPK2 (NP_997198).
Isotype IgG
Source/Host Rabbit
Species Reactivity Mouse, Rat, Human
Purification Immunogen affinity purified
Conjugate Unconjugated
Applications WB, ICC/IF
Format Liquid
Size 100 μl
Buffer Constituent: 99% PBS
Preservative 0.02% Sodium Azide
Storage Store at 4°C or -20°C long term. Avoid repeated freeze / thaw cycles. Store undiluted.
GENE INFORMATION
Gene Name CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial [ Homo sapiens ]
Official Symbol CMPK2
Synonyms CMPK2; cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial; UMP-CMP kinase 2,
45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]
Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved mitochondrial; cytidylate kinase 2; TYKi; UMP CMPK2; mitochondrial UMP-CMP kinase; thymidine monophosphate kinase 2; thymidylate kinase family LPS-inducible member; TMPK2; UMP-CMPK2;
Entrez Gene ID 129607
Protein Refseq NP_001243406
UniProt ID Q5EBM0
Chromosome Location 2p25.2
Pathway Metabolic pathways; Pyrimidine metabolism; Pyrimidine ribonucleotide biosynthesis, UMP =>UDP/UTP,CDP/CTP;
Function ATP binding; UMP kinase activity; cytidylate kinase activity; kinase activity; nucleotide binding; thymidylate kinase activity; transferase activity
45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]
Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved