Helen Mayberg to Speak on September 18

PsychCommonsConnecting News and People In Our Department Greenfield Lecture - Helen Mayberg to Speak on September 18

The 2014 Greenfield Lecture will feature Helen Mayberg, fast as possible, using the treatment that is best for each MD, Professor of Psychiatry, Neurology, and Radiology and individual.” the Dorothy C. Fuqua Chair of Psychiatric Neuroimaging and Therapeutics at Emory University. Dr. Mayberg heads “These data suggest that if you treat based on a patient’s a multidisciplinary depression research program dedicated brain type, you increase the chance of getting them into to the study of brain circuits in depression and the effects remission,” says Dr. Mayberg. More study is needed to of various antidepressant treatments confirm how this approach may be used measured using a variety of functional to deliver treatments more effectively and structural imaging tools. The pri- and how to apply it to different types of mary focus of her lab is to development depression. imaging and physiological based algo- rithms that will discriminate depressed Dr. Mayberg will speak at WisPIC in room patient subgroups and optimize treatment 1616 at 5:30pm on Thursday, September selection at all stages of the illness. Imag- 18. The Greenfield lecture honors the ing findings provided the foundation for legacy of Norman S. Greenfield, former development and testing of deep brain Professor of Psychiatry and Associate stimulation (DBS) of the subcallosal cin- Director and co-founder of the Wisconsin gulate region (Area 25), a novel interven- Psychiatric Institute. Greenfield played tion for patients with treatment resistant an early key role in fostering scientific depression. research in psychiatry as he pursued his interest in understanding the role of Mayberg notes that currently, fewer than psychophysiological correlates of psycho- 40% of patients treated for major depressive disorder logical disorder and the processes involved in personality achieve remission with initial treatment. Identification of a change, as exemplified by his books “Psychoanalysis and biological marker that might improve these odds could have Current Biological Thought” and the “Handbook of Psycho- significant health and economic impact. Her recent work physiology”. He was very dedicated to the supervision of focused on identiying a biomarker that could predict which psychiatry residents preparing them to effectively integrate type of treatment a patient would benefit from based on the psychotherapy with pharmacology in their treatment of individual’s brain activity. The research team measured the patients. The early values he brought to the Department of critical brain function of brain glucose metabolism in two Psychiatry, using rigorous scientific methods to integrate groups of participants during a period of 12 weeks. After psychology with psychiatry to improve the lives of those having a PET scan, half of the participants were given an suffering from mental illness, continue today as the Depart- antidepressant medication and the other half were given ment of Psychiatry’s guiding principles. cognitive behavior therapy (CBT).The researchers found that less activity in the brain’s anterior insula indicated response to CBT, and more activity indicated response to medication. Greenfield Lecture: Thursday, September 18, 5:30pm, WisPIC room 1616. Contact “To be ill with depression any longer than necessary can Vanessa Balchen if you wish to meet with Dr. be perilous,” says Dr. Mayberg, Professor of Psychiatry, Mayberg while she is here. Neurology, and Radiology, Emory University School of Medicine. “This is a serious illness and the prolonged suffering resulting from an ineffective treatment can have serious medical, personal and social consequences. Our goal is not just to get patients well, but to get them well as Spring, 2014

UW Psychiatry Turns-Out Big for SOBP

UW Psychiatry had a strong turn-out at the annual Soci- ety of Biological Psychiatry (SOBP) meeting held in New York City in May.

Besides the awards noted in the photos, numerous students and faculty presented their work at the meeting.

SOBP encourages the study of the biological caus- David Plante, MD received the Chair’s Choice NTP student, Do Tromp won one of 32 blue es of and treatments for award which was awarded to outstanding young ribbons awarded to translational research post- psychiatric disorders. The scientists with an interest in biological psychia- ers. She then went on the win Top Translational organization seeks to pro- try. Poster award. mote excellence in scientific research and education in fields that investigate the nature, causes, mechanisms, and treatments of disorders of thought, emotion, or behavior.

Poster presenters (in bold) included:

David T. Plante, Michael Pat Roseboom, PhD won one of 32 blue ribbons R. Goldstein, Jessie D. awarded to translational research posters. Over 1500 posters were presented. Cook, Richard Smith, Brady A. Riedner, Meredith E. Rumble, Lauren Jelenchick, PGY3 Brendon Nacewicz and PGY2 Fabio Giulio Tononi, Ruth M. Ferrarelli received Travel Fellowship awards that Benca, Michael J. Peterson awarded them each a $2000 stipend to defray travel costs and complimentary meeting regis- - Effects of Oral Temaze- tration for 3 years. pam on Spectral Activity and Sleep Spindles During Non-rapid Eye Movement Sleep: A High-density EEG Investigation Department Chair, Ned Kalin, MD is the SOBP President for Do P. M. Tromp, Andrew S. 2014-2015. The 2015 meeting Fox, Jonathan A. Oler, Pat- will be held in Toronto, Canada. rick H. Roseboom, Andrew L. Alexander, Ned H. Kalin - Early Life Adversity Leads

Sisi Li (Alisch Lab) presents her poster at (continued on page 3) one of the sessions page 2 Spring, 2014

SOBP continued from page 2 Awards and to Aberrant Structural Development Richard Wolf, Ryan Herringa - Accolades of Amygdala-prefrontal Network in Altered Prefrontal Function Follow- Non-human Primates ing Affective Priming in Pediatric The Department of Psy- Post-Traumatic Stress Disorder chiatry was recognized Andreas Buchmann, Daniela Den- for its silver sponsorship tico, Michael J. Peterson, Brady A. Remi Patriat, Ryan Herringa - De- donation to Journey Mental Riedner, Simone Sarasso, Marcel- fault Mode Network Connectivity in Health Center’s May 31 Big lo Massimini, Giulio Tononi, Fabio Pediatric PTSD Dreams Ball: Starry Night Ferrarelli - Reduced Mediodorsal fundraiser. The event raised Thalamic Volume and Prefrontal Taylor J. Keding, Ryan J. Herrin- $65,000. Cortical Spindle Activity in Schizo- ga - Functional Neural Correlates phrenia of Emotion Regulation in Pediatric Ron Diamond, MD, Profes- Post-traumatic Stress Disorder sor of Psychiatry has been Patrick H. Roseboom, Jonathan appointed to the Milwau- A. Oler, Andrew S. Fox, Ned H. Presentations: kee County Mental Health Kalin - Mifepristone Decreases Board by Wisconsin Gover- Anxiety-like Behaviors in a Non-hu- Andrew Fox presented “Structural nor Scott Walker. man Primate Model of Anxious and Functional Neural Systems Temperament Underlying Increased Genetic Risk Douglas Kramer, MD, for Anxiety in a Large Sample of Emeritus Professor of Carissa L. Philippi, Julian C. Mot- Nonhuman Primates” in a ses- Psychiatry has been elect- zkin, Ian Carroll, Michael Koenigs sion he co-chaired on Integrating ed to the position of Coun- - Self-Focus Task Performance Genetic and Neuroimaging Data to cilor-at-Large by the The Predicts Default Mode Network Understand Psychiatric Disorders American Academy of Child Connectivity at Rest in Primates and Adolescent Psychiatry.

Brendon M. Nacewicz, Andrew L. Ned H. Kalin presented “The Neu- Ruth Benca, MD, Profes- Alexander, Ned H. Kalin, Richard ral Substrates of Anxiety Vulnera- sor of Psychiatry has been J. Davidson - The Neurochemical bility” in a session he co-chaired on awarded an academic Underpinnings of Human Amygda- Childhood Anxiety: Risk, Develop- distinction by the School la Volume Including Subregional ment, and Treatment of Medicine and Public Contributions health; she is now the Jan Dr. Kalin also co-chaired a session and Kathryn Ver Hagen Sisi Li, Ligia Papale, Reid Alisch - on The Neurobiology of Pervasive Professor of Translational Studies of a Brain-enriched Epi- Anxiety: The Role of Circuits Cen- Research. genetic Mark Reveals Sex Differ- tered on the Extended Amygdala ences and a Genome-wide Loss in where Alexander Shackman pre- Fabio Ferrarelli (PGY2) has Response to Acute Stress sented “The Extended Amygdala is been selected for an NIMH a Key Substrate for Extreme Anxi- Outstanding Resident Mitzy Kennis, Sanne J. H. van ety Early in Life”. Shackman did his Award for 2014. This award Rooij, Do P. M. Tromp, Arthur R. doctoral and post-doctoral work in recognizes Fabio’s accom- Rademaker, René S. Kahn, Ned the UW labs of Kalin and Davidson plishments in functional H. Kalin, Elbert Geuze - Alterations and is now an Assistant Professor neuroanatomy of sleep in in White Matter Tracts in Veterans at University of Maryland. patients with schizophrenia. with PTSD versus without PTSD and Healthy Controls

page 3 Spring, 2014

Dedication of Birdroom to Honor Dick Anderson, MD

The Department of Psychiatry will honor the legacy of ing pristine prints from an aunt. Committed to sharing Richard (Dick) B. Anderson, MD on Wednesday, July them, he donated dozens of prints, which now hang in 23 at 5:30pm in WisPIC room 1219 by renaming the various locations throughout the UW-Madison cam- Birdroom the Anderson Audubon Room. pus, including those prints hanging in WisPIC 1219. He also established the Audubon Room within the Dr. Anderson earned a bachelor’s and Overture Center so the public could medical degree from the University of enjoy some of his prized artwork. Wisconsin. He completed his residency at Barnes Hospital in St. Louis and Even in his later years, Anderson found returned to Madison in 1953 where he ways to give back to the community. began practicing general pediatrics at When the Medical Scholars Program Wisconsin General Hospital. In 1968, was discontinued in 2007, Anderson he left Madison to pursue an adoles- rallied his class to redirect its endowed cent medicine fellowship at Harvard fund to the MEDiC student-run free University. With an interest in child clinics; it now funds MEDiC’s annual psychiatry, he returned to Madison and expenses. MEDiC is a student-run joined the School of Medicine and Pub- program of the University of Wisconsin lic Health faculty with appointments in School of Medicine and Public Health child psychiatry and pediatrics. Believ- and is comprised of seven health ing that all pediatricians could benefit clinics throughout Madison. Dick’s love from a familiarity with child and adoles- of Audubon and his commitment to cent psychiatry, Anderson organized share with the university community led the child and adolescent consultation program, which to his donation of the prints that grace the walls the served as a link between the two fields and started Birdroon. Please make plans to attend the ceremony, Wisconsin’s first eating disorder clinic. refreshments will be served.

Anderson took great pride in an extensive Audubon collection, which he started decades ago upon inherit-

20th Annual Wisconsin Symposium on Emotion

The HealthEmotions Research Institute hosted the and networking with 20th annual Wisconsin Symposium on Emotion in fellow attendees and April. The symposium is a highly regarded opportu- speakers. 16 students nity to learn and network with some of the biggest attended with travel names in neuroscience in an intimate setting. This awards and over 40 year was no different with Julie Fudge, MD, Rene posters were pre- Hen, PhD, Pat Levitt, PhD, Tim Oberlander MD, and sented at the poster Kay Tye, PhD all leading an exploration of the topic: session in Varsity Hall. Neural Bases of Adaptive and Maladaptive Emo- The speakers and UW tion Regulation. Audience participation in the Q&A faculty were generous with their time, interacting sessions after each presentation were spirited and with the presenters, asking questions, and encour- thought-provoking. aging their work.

This year the symposium moved to the Marquee The 21st annual Wisconsin Symposium on Emotion Theater in Union South and the location and ame- will be held April 22 - 23, 2015 at Union South. De- nities offered a better arrangement for meeting tails will be on the website by the end of the year.

page 4 Spring, 2014

Claudia Reardon, MD Jake Behrens, MD Wins Receives Rising Star Award Leadership Award

Claudia Reardon, MD, The Wisconsin Medical Society Foundation honored Assistant Professor of Psy- Jake Behrens, MD with the Kenneth M. Viste, Jr., chiatry was awarded the MD, Young Physician Leadership Award on April 5. UW Health Rising Star An assistant clinical professor in the Department of Physician award last month. Psychiatry at the University of Wisconsin School of UW Medical Foundation Medicine and Public Health, Dr. Behrens received president and CEO Jeffrey the award during the Wisconsin Medical Society’s Grossman, MD, presented Annual Meeting in Green Bay. The Viste Award is the Rising Star Award to Dr. presented annually to a young physician who demon- Reardon, MD, and noted strates commitment to patients, the medical profes- that her significant contribu- sion and the community. tions “suggest an exemplary career trajectory.” Dr. Behrens’ area of expertise is Grossman called Reardon an “outstanding clinician attention-deficit/ and educator,” pointing to her efforts in curriculum hyperactivity design and teaching at the UW School of Medicine disorder. He has and Public Health. In her brief career she has been recently served heavily involved in providing expertise to local and as chair of the national media for stories on exercise and mental American Psychi- health as well as sports psychiatry. Her advocacy atric Association contributed to a change in state legislation regarding Assembly Com- concussions in youth athletics. mittee of Mem- bers in Training “Her clinical activity embodies the mission compo- and has helped nents of service, scholarship, science and social integrate social responsibility,” said Grossman. “She is a person who media at national clearly reflects the values of UW Health.” meetings. He has significantly helped to recruit young members to the “These awards were created to recognize some Wisconsin Psychiatric Association Executive Council of our most respected UW Health physicians who and has been part of a Wisconsin Medical Society demonstrate exceptional skill in clinical practice, Membership Summit Task Force. In addition, two education or outreach, and their commitment to the years ago he was chosen as the only resident to mission, vision and values of UW Health,” said UW serve on a Reference Committee at the Wisconsin Medical Foundation vice president of human resourc- Medical Society Annual Meeting. es Bill Schrum, who presided over the presentation. “Doctor Behrens epitomizes the type of leader the Physician Excellence Award nominees are consid- Wisconsin Medical Society Foundation hopes to de- ered for the awards based on a nomination from velop. He possesses the rare capability as a young at least one UW Health colleague and as many as physician of seeing the ‘big picture’ of health care, three physicians and clinicians from UW Health or including the intersection of quality of, cost of, and health care organizations around the state and be- access to health care,” said Claudia Reardon, MD, yond. assistant professor and associate residency training director and chair of the Wisconsin Medical Society “What is unique about these awards is that they are Foundation Scholarship Committee, in her nomina- peer-nominated awards,” said Schrum. tion letter.

page 5 Spring, 2014

HIPAA Harmonization Bill by Michael Peterson, MD

The HIPAA (Health Insurance Portability and Acount- notes”) are defined as detailed docu- ability Act) Harmonization bill was signed into law by mentation of psychotherapy sessions, Governor Walker this Spring. This bill will facilitate the kept only for the use of the therapist and “harmonization” of Wisconsin law regarding mental not intended for use by other providers or the pa- health care records with Federal law. tient. These notes need to be maintained in a secure, private method and are not in the Electronic Medical In short, patient medical records are legally protected Record (EMR. e.g. - HealthLink). documents. HIPAA was intended to provide a national standard for secure maintenance of health records, This law will make Wisconsin law consistent with the and to define how they can be shared. However, standards set in federal HIPAA rules, and will allow disclosure of mental health records are defined by better access between providers of: medication mon- both HIPAA and a more restrictive set of Wisconsin itoring notes, clinical test results, summaries of pa- state laws. The state laws end up requiring additional tient’s diagnoses and symptoms, and other pertinent measures which make coordination of patient care be- medical (psychiatric and non-psychiatric) information. tween providers more complicated and difficult. Some examples of these rules include the requirement that In principle it should simplify and reduce additional pri- all mental health records be maintained separately vacy measures on mental health records that exceed - mandating the use of a system such as “Break the federal HIPAA laws. Glass” which many of you have seen in Health Link. There are additional restrictions on sharing discharge At this time we are working with risk, legal and privacy summaries from a psychiatric hospitalization with out- officers for UWHC and UW Health to evaluate the law, patient providers (either mental health, primary care, and we will convene a working group to determine or other specialty). For most non-psychiatric hospi- what changes we will implement organizationally. talizations, these records can be shared with implicit consent from patients. Psychiatric records require an Michael Peterson, MD, PhD is an Assistant Professor of Psychiatry at the University of Wisconsin additional written consent for release of records, and a mechanism for medical records staff to confirm this before sending them. Art Walaskek Awarded Some may argue that mental health/psychiatric “Courage to Teach” Award records should be accorded a higher level of pro- tection, given the risk of stigma and sensitivity of the Art Walaszek, MD, Associate Professor and Vice records. However, these restrictions may actually Chair of Education, was awarded the Parker J. increase the risk to patients. Restrictions on sharing Palmer Courage to Teach Award by the Accred- records between providers increases the risk of miss- itation Council for Graduate Medical Education ing important information about medical conditions, (AGGME) at their annual meeting in Maryland. This prescriptions (and interactions between medications), award honors program directors allergies, and other critical information that could who find innovative ways to teach impact subsequent care. If the ER physician doesn’t residents and to provide quali- know about the patient’s prescription for lithium, they ty health care while remaining may not detect critical drug levels or kidney problems connected to the initial impulse that could be life threatening. The primary care doctor to care for others in this envi- who doesn’t know about the new antidepressant pre- ronment. Parker J. Palmer, PhD scription could prescribe another medication that has is the author of the book The a risky interaction. Courage to Teach and whose promotion of the concept of “living However, certain types of highly sensitive notes would divided no more” has proven relevant to teaching in still not be shared. Psychotherapy notes (or “process academic health centers.

page 6 Spring, 2014

Summer Grand Rounds Katherine Perreth - July 25 Charles Nemeroff, MD - August 29

Friday, July 25 our speaker will be Katherine Perreth Friday, August 29 our speaker will and her son Ben. Katherine is the author of the book be Charles Nemeroff, MD, Leon- Making Lemonade With Ben: The Audacity to Cope. ard M. Miller Professor & Chair- man, Department of Psychiatry Ms. Perreth’s book is the compelling story of sixteen and Behavioral Sciences and Di- years of Ben’s life. It begins with the night a Universi- rector, Center on Aging, University ty of Wisconsin Hospital neurosurgeon saved Ben’s of Miami Leonard M. Miller School life, and follows Ben through young adulthood. Al- of Medicine. though he encounters years of substantial obstacles, including mental health issues, his never-say-die atti- Dr. Nemeroff graduated from City tude ultimately carries him to the White House as a College of New York in 1970, he received a Master’s community representative for the Madison Children’s degree in Biology from Northeastern University in Museum. Themes of perseverance and compassion 1973. He received his M.D. and Ph.D. in Neurobiol- encourage readers to contemplate contemporary is- ogy from the University of North Carolina at Chapel sues: mental illness treatment, recovery and stigma, Hill. the role of intentional employers in the lives of those with disabilities, and the success that can occur Nemeroff completed residencies in psychiatry at both when a community values all citizens. the University of North Carolina and Duke University, where he joined the faculty after completion. While at Ms. Perreth holds degrees in Social Work and Duke, he was Professor of Psychiatry and Pharma- cology and Chief of the Division of Biological Psychi- atry. In 1991, Dr. Nemeroff relocated to the Emory University School of Medicine in Atlanta, Georgia, where he served as a professor in the Department of Psychiatry and Behavioral Sciences. In his 18 years of service, he transformed the psychiatry department into one of the top ten departments in the United States. Since 2009, he has served as the Leonard M. Miller Professor and Chairman of the Department of Psychiatry and Behavioral Sciences at the Univer- sity of Miami. Sociology from the University of Wisconsin - Madi- son. She is a reporter for her hometown newspaper, His research concentrates on the biological basis of the Middleton Times Tribune, conducts a class on major neuropsychiatric disorders, including affective reminiscence writing, and is an administrative staff disorders, schizophrenia and anxiety disorders. His with WESLI (an ESL school on the capitol square). clinical research has recently focused on the use of Ben, lives on his own in downtown Madison and is a neuroendocrine, neuroimaging and neurochemical member of Yahara House. Wearing his ankle-foot-or- methods to elucidate the pathophysiology of depres- thosis with a smiley face on the back, Ben juggles sion. In recent years Nemeroff has sought to deter- one-handed at the Madison Children’s Museum as a mine the neurobiological mechanisms that mediate Discovery Guide. Ben continues to aim for his life’s the increased risk for depression in individuals who goal: “Make humanity smile.” were victims of child abuse. He has also contributed to the burgeoning area of research concerning the relationship of depression to cardiovascular disease.

page 7 Spring, 2014 Publications Albrecht, D. S., Kareken, D. A., Chung, M. K., Hanson, J. L., Lee, medial Prefrontal Cortex Activity’, J Christian, B. T., Dzemidzic, M. and H., Adluru, N., Alexander, A. L., Cogn Neurosci. Yoder, K. K. (2014) ‘Cortical dopa- Davidson, R. J. and Pollak, S. D. mine release during a behavioral (2013) ‘Persistent homological Hillmer, A. T., Tudorascu, D. L., response inhibition task’, Synapse, sparse network approach to de- Wooten, D. W., Lao, P. J., Barn- 68(6), 266-74. tecting white matter abnormality hart, T. E., Ahlers, E. O., Resch, L. in maltreated children: MRI and M., Larson, J. A., Converse, A. K., Armstrong, J. M., Ruttle, P. L., DTI multimodal study’, Med Im- Moore, C. F., Schneider, M. L. and Klein, M. H., Essex, M. J. and age Comput Comput Assist Interv, Christian, B. T. (2014) ‘Changes in Benca, R. M. (2014) ‘Associations 16(Pt 1), 300-7. the alpha4beta2* nicotinic ace- of child insomnia, sleep movement, tylcholine system during chronic and their persistence with mental Converse, A. K., Ahlers, E. O., controlled alcohol exposure in health symptoms in childhood and Travers, B. G. and Davidson, R. nonhuman primates’, Drug Alcohol adolescence’, Sleep, 37(5), 901-9. J. (2014) ‘Tai chi training reduces Depend, 138, 216-9. self-report of inattention in healthy Baisley, S. K., Bremer, Q. Z., young adults’, Front Hum Neuros- Hosseinbor, A. P., Chung, M. K., Bakshi, V. P. and Baldo, B. A. ci, 8, 13. Schaefer, S. M., van Reekum, C. (2014) ‘Antipsychotic-like actions M., Peschke-Schmitz, L., Sutterer, of the satiety peptide, amylin, in de Vivo, L., Faraguna, U., Nel- M., Alexander, A. L. and Davidson, ventral striatal regions marked by son, A. B., Pfister-Genskow, M., R. J. (2013a) ‘4D hyperspherical overlapping calcitonin receptor Klapperich, M. E., Tononi, G. and harmonic (HyperSPHARM) repre- and RAMP-1 gene expression’, J Cirelli, C. (2014) ‘Developmental sentation of multiple disconnected Neurosci, 34(12), 4318-25. patterns of sleep slow wave activity brain subcortical structures’, Med and synaptic density in adoles- Image Comput Comput Assist Barrineau, M. J., Zarit, S. H., King, cent mice’, Sleep, 37(4), 689-700, Interv, 16(Pt 1), 598-605. H. A., Costanzo, E. S. and Almei- 700a-700b. da, D. M. (2014) ‘Daily well-being Hosseinbor, A. P., Chung, M. K., of cancer survivors: the role of so- Farmer, C., Butter, E., Mazurek, M. Wu, Y. C., Alexander, A. L. and matic amplification’, Psychooncol- O., Cowan, C., Lainhart, J., Cook, Bendlin, B. B. (2013b) ‘A 4D hyper- ogy. E. H., Dewitt, M. B. and Aman, M. spherical interpretation of q-space’, (2014) ‘Aggression in children with Med Image Comput Comput Assist Benjamin, S., Travis, M. J., Coo- autism spectrum disorders and a Interv, 16(Pt 3), 501-9. per, J. J., Dickey, C. C. and Rear- clinic-referred comparison group’, don, C. L. (2014) ‘Neuropsychiatry Autism. Ingram, D. G., Matthews, C. K. and neuroscience education of and Plante, D. T. (2014) ‘Seasonal psychiatry trainees: attitudes and Gaffey, A. E., Wirth, M. M., Hoks, trends in sleep-disordered breath- barriers’, Acad Psychiatry, 38(2), R. M., Jahn, A. L. and Abercrom- ing: evidence from Internet search 135-40. bie, H. C. (2014) ‘Circulating corti- engine query data’, Sleep Breath. sol levels after exogenous cortisol Birn, R. M., Shackman, A. J., Oler, administration are higher in women Jones, S. G., Riedner, B. A., Smith, J. A., Williams, L. E., McFarlin, using hormonal contraceptives: R. F., Ferrarelli, F., Tononi, G., D. R., Rogers, G. M., Shelton, S. Data from two preliminary studies’, Davidson, R. J. and Benca, R. E., Alexander, A. L., Pine, D. S., Stress. M. (2014) ‘Regional reductions Slattery, M. J., Davidson, R. J., in sleep electroencephalography Fox, A. S. and Kalin, N. H. (2014) Heller, A. S., Lapate, R. C., May- power in obstructive sleep apnea: ‘Evolutionarily conserved pre- er, K. and Davidson, R. J. (2014) a high-density EEG study’, Sleep, frontal-amygdalar dysfunction in ‘The Face of Negative Affect: Tri- 37(2), 399-407. early-life anxiety’, Mol Psychiatry. al-by-Trial Corrugator Responses to Negative Pictures Are Positively Carrera, E. and Tononi, G. (2014) Associated with Amygdala and ‘Diaschisis: past, present, future’, Negatively Associated with Ventro- Continued on page 8 Brain. page 8 Spring, 2014

Publications (continued) Kaliman, P., Alvarez-Lopez, M. J., correlates of age effects on ver- Peng, Y., Li, M., Clarkson, B. D., Cosin-Tomas, M., Rosenkranz, M. bal-spatial binding in working Pehar, M., Lao, P. J., Hillmer, A. A., Lutz, A. and Davidson, R. J. memory’, Behav Brain Res, 266, T., Barnhart, T. E., Christian, B. (2014) ‘Rapid changes in histone 146-52. T., Mitchell, H. A., Bendlin, B. B., deacetylases and inflammatory Sandor, M. and Puglielli, L. (2014) gene expression in expert medita- Michelson, D., Snyder, E., Paradis, ‘Deficient Import of Acetyl-CoA into tors’, Psychoneuroendocrinology, E., Chengan-Liu, M., Snavely, D. the ER Lumen Causes Neurode- 40, 96-107. B., Hutzelmann, J., Walsh, J. K., generation and Propensity to Infec- Krystal, A. D., Benca, R. M., Cohn, tions, Inflammation, and Cancer’, J Kamasak, M. E., Christian, B. T., M., Lines, C., Roth, T. and Herring, Neurosci, 34(20), 6772-89. Bouman, C. A. and Morris, E. D. W. J. (2014) ‘Safety and efficacy (2014) ‘Quality and precision of of suvorexant during 1-year treat- Philippi, C. L. and Koenigs, M. parametric images created from ment of insomnia with subsequent (2014) ‘The neuropsychology of PET sinogram data by direct abrupt treatment discontinuation: a self-reflection in psychiatric illness’, reconstruction: proof of concept’, phase 3 randomised, double-blind, J Psychiatr Res, 54c, 55-63. IEEE Trans Med Imaging, 33(3), placebo-controlled trial’, Lancet 695-707. Neurol, 13(5), 461-71. Pisano, E. D., Golden, R. N. and Schweitzer, L. (2014) ‘Conflict Lapate, R. C., van Reekum, C. Motzkin, J. C., Baskin-Sommers, of interest policies for academic M., Schaefer, S. M., Greischar, A., Newman, J. P., Kiehl, K. A. health system leaders who work L. L., Norris, C. J., Bachhuber, D. and Koenigs, M. (2014a) ‘Neural with outside corporations’, Jama, R., Ryff, C. D. and Davidson, R. J. correlates of substance abuse: 311(11), 1111-2. (2014) ‘Prolonged marital stress is Reduced functional connectivity associated with short-lived re- between areas underlying reward Pitula, C. E., Thomas, K. M., Arm- sponses to positive stimuli’, Psy- and cognitive control’, Hum Brain strong, J. M., Essex, M. J., Crick, chophysiology, 51(6), 499-509. Mapp. N. R. and Gunnar, M. R. (2014) ‘Peer Victimization and Internaliz- Li, C. T., Palotti, M., Holden, J. E., Motzkin, J. C., Philippi, C. L., Wolf, ing Symptoms Among Post-Institu- Oh, J., Okonkwo, O., Christian, R. C., Baskaya, M. K. and Koe- tionalized, Internationally Adopted B. T., Bendlin, B. B., Buyan-Dent, nigs, M. (2014b) ‘Ventromedial Youth’, J Abnorm Child Psychol. L., Harding, S. J., Stone, C. K., Prefrontal Cortex Is Critical for the Dejesus, O. T., Nickles, R. J. and Regulation of Amygdala Activity in Plante, D. T. (2014) ‘Leg actig- Gallagher, C. L. (2014) ‘A du- Humans’, Biol Psychiatry. raphy to quantify periodic limb al-tracer study of extrastriatal 6-[ movements of sleep: A systematic F]fluoro-m-tyrosine and 6-[ F]-flu- Nielsen, J. A., Zielinski, B. A., review and meta-analysis’, Sleep oro-l-dopa Uptake in Parkinson’s Fletcher, P. T., Alexander, A. L., Med Rev. disease’, Synapse. Lange, N., Bigler, E. D., Lainhart, J. E. and Anderson, J. S. (2014) Schaefer, H. S., Larson, C. L., Marceau, K., Ruttle, P. L., Shirtcliff, ‘Abnormal lateralization of function- Davidson, R. J. and Coan, J. A. E. A., Essex, M. J. and Susman, E. al connectivity between language (2014) ‘Brain, body, and cogni- J. (2014) ‘Developmental and con- and default mode regions in au- tion: Neural, physiological and textual considerations for adrenal tism’, Mol Autism, 5(1), 8. self-report correlates of phobic and and gonadal hormone functioning normative fear’, Biol Psychol, 98, during adolescence: Implications Oizumi, M., Albantakis, L. and 59-69. for adolescent mental health’, Dev Tononi, G. (2014) ‘From the phe- Psychobiol. nomenology to the mechanisms of Reardon, C., May, M. and Williams, consciousness: integrated informa- K. (2014) ‘Psychiatry Resident Meier, T. B., Nair, V. A., Meyer- tion theory 3.0’, PLoS Comput Biol, Outpatient Clinic Supervision: How and, M. E., Birn, R. M. and Pra- 10(5), e1003588. Training Directors Are Balancing bhakaran, V. (2014) ‘The neural Patient Care, Education, and Re- imbursement’, Acad Psychiatry. page 9 Spring, 2014 Events - Save the Date Publications continued Monday, June 23: Seminar, 3:30- Friday, September 12: Grand Sridharan, A., Bendlin, B. B., Gal- 4:30pm, HERI Classroom, “TBA”, Rounds, 12:00 - 1:00pm, WisPIC lagher, C. L., Oh, J. M., Willette, Roxann Roberson-Nay, PhD room 1616. “Defining the role of A. A., Alexander, A. L., Kemnitz, epigenetics in the development Friday, June 27: Psychiatry J. W., Colman, R. J., Weindruch, of anxiety and depression”, Reid Psumer Psunset, 5:30pm, Memo- Alisch, PhD, Assistant Professor, R. H. and Johnson, S. C. (2014) rial Union Terrace. ‘Effect of age and calorie restriction Psychiatry, University of Wiscon- on corpus callosal integrity in rhe- Friday, July 4: Holiday, Depart- sin sus macaques: A fiber tractography ment of Psychiatry will be closed. Thursday, September 18: Green- study’, Neurosci Lett, 569, 38-42. Tuesday, July 8: Welcome Re- field Memorial Lecture, 5:30pm, WisPIC room 1616. “TBA”, Helen Taber-Thomas, B. C., Asp, E. W., ception, 5:30pm, WisPIC 1616 Mayberg, MD, Professor of Psy- Koenigs, M., Sutterer, M., Ander- Wednesday, July 23: Dedication chiatry, Neurology, and Radiology, son, S. W. and Tranel, D. (2014) of the Anderson Audubon Room, Emory University. Refreshments ‘Arrested development: early 5:30pm, WisPIC 1219. Refresh- will be served. prefrontal lesions impair the matu- ments will be served. ration of moral judgement’, Brain, Sunday, October 5: NAMI Walk, 137(Pt 4), 1254-61. Friday, July 25: Grand Rounds, 12:00pm, Olin Turville Park 12:00 - 1:00pm, WisPIC 1616. Wolf, R. C., Philippi, C. L., Motzkin, Katherine J. Perreth, author of Tuesday, October 7: Focus on J. C., Baskaya, M. K. and Koenigs, “Making Lemonade With Ben: The Mental Health public lecture fea- M. (2014) ‘Ventromedial prefron- Audacity to Cope” and Ben Per- turing Dr. Ron Diamond and Dr. talcortex mediates visual attention reth Ned Kalin, 6:30pm, room 1616 during facial emotion recognition’, Thursday, October 9: National Brain, 137(Pt 6), 1772-80. Friday, August 29: Grand Rounds, 12:00 - 1:00pm, WisPIC Depression Screening Day event, 11:00am - 1:00pm, Madison Cen- Zielinski, B. A., Prigge, M. B., 1616. “TBA”, Charles B. Nemeroff, tral Library, 201 W Mifflin St. Con- Nielsen, J. A., Froehlich, A. L., MD, PhD, the Leonard M. Miller tact Vanessa Balchen to volunteer Abildskov, T. J., Anderson, J. S., Professor and Chair of Psychiatry and Behavioral Sciences, Univer- Fletcher, P. T., Zygmunt, K. M., Tra- Friday, October 10 - Saturday, sity of Miami, Florida vers, B. G., Lange, N., Alexander, October 11: Annual Updates and A. L., Bigler, E. D. and Lainhart, J. Monday, September 1: Labor Advances in Psychiatry, Monona E. (2014) ‘Longitudinal changes Day holiday, Department of Psy- Terrace in cortical thickness in autism and chiatry will be closed. typical development’, Brain, 137), 1799-812.

Postle Lab Connects with Edgewood College

Mike Starret (left), Research Assistant and Brad Pos- tle (middle), Professor of Psychiatry demonstrated the TMS equipment to an undergraduate Psychol- ogy class taught by Edgewood Assistant Professor, Ferrine Spector, PhD (far right).

page 10 Spring, 2014 Ben’s Ride Raises $9k to Fund Health Emotions Research

When Ben Sullivan died of suicidal depression in 2009, his family established Ben’s Ride to Fund Depression & Anxiety Research. Sue, Ted and Tim Sullivan wanted to extend Ben’s legacy by celebrating his life, funding depression and anxiety research, and encouraging conversations about mental illness. The 2014 Ride was held on a May 17 and UW Psychiatry Outreach Specialist, Va- nessa Balchen attended to help explain the Kalin Lab research and to discuss how to start conversations about mental illness. Ben’s family and friends shared their rememberances about Ben and his love of cycling and science. The ride raised $9,000 to help fund the research of the Kalin Lab. The Sullivans believe it is crucial to encourage the open discussion of mental illness in order to lessen stigma and help people feel more at ease in seeking the help they need. Pictured above: group photo of all the volunteers, family and friends; a group of riders enjoying the day; Vanessa Balchen, Sue Sullivan, and a volunteer talking about mental illness.

Update and Advances in Psychiatry Conference October 10-11, 2014

The annual Updates and Advances in Psychiatry conference will be Friday, October 10 and Saturday, October 11 at Monona Terrace. Speakers will be:

Maria Oquendo, MD, Professor of Clinical Psychiatry, Director, Clinical Studies in Molecular Imaging and Neuropathology Division, NYS Psychiatric Institute and Columbia University - Update on the Neuro- biology, Assessment and Treatment of Suicidality

Zachary Stowe, MD, Professor of Psychiatry, Medical Director, Women’s Mental Health Program, Uni- versity of Arkansas Psychiatric Research Institute - Update on the Treatment of Mood Disorders During Pregnancy and Postpartum

Ken Towbin, MD, Chief, Clinical Child and Adolescent Psychiatry, Emotion and Development Branch, National Institute of Mental Health - Overview of Disruptive Mood Dysregulation Disorder

Roger McIntyre, MD, FRCPC, Professor of Psychiatry and Pharmacology at the University of Toronto - Update on the Treatment of Bipolar Depression

Ned Kalin, MD - Update on the Neurobiology of Depression

Art Walaszek, MD - Update on the Assessment and Treatment of Late-Life Depression

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