Advancing Research at Virginia Tech

Department of Science www.cs.vt.edu

Computational Biology and

https://bioinformatics.cs.vt.edu/cbb

Contact Information: Selected Research Programs:

Christopher L. Barrett, (540) 231-1745, [email protected], Simulation science • xMotif software package for extracting subtle patterns of Vicky Choi, (540) 231-2919, [email protected], in gene co-expression from gene expression data bioinformatics, , , • New physics-based computational methodologies used to computational , and discrete Roger W. Ehrich, (540) 231-5420, [email protected], Digital picture understand dynamics of large biomolecular systems processing and image analysis • Applying the "implicit solvation methodology" for Lenwood Heath, (540) 231-4352, [email protected], Expresso, promoter effectively representing solvation effects in biological analysis, multimodal models, experimental data analysis and mining, system modeling and rational drug design, vs. protein experimental design folding, assembly of protein-protein and protein-DNA Madhav Marathe, (540) 231-8832, [email protected], Modeling and simulation of large scale socio-technical and biological complexes systems, computational complexity theory, combinatorial optimization • Fluid dynamics of blood flow, protein folding and T.M. Murali, (540) 231-8534, [email protected], Computational molecular docking, microarray image analysis, and functional genomics and computational systems biology modeling of microarray experimental processes Chris North, (540) 231-2458, [email protected], Human-computer • interaction, information , software Problem solving environments and biochemical reaction Alexey Onufriev, (540) 231-4237, [email protected], Dynamics of large networks (JigCell) are being developed with funding from biomolecular systems, biomolecular electrostatics, molecular biophysics. DARPA, NIH, and NSF Naren Ramakrishnan, (540) 231-8451, [email protected], Software • Automatic whole-genome functional annotation using problem solving environments, recommender systems, , and functional linkage graphs personalization Adrian Sandu, (540) 231-2193, [email protected], Multi-step methods for • Understanding conservation and divergence of function in biomolecular modeling plant gene orthologs using heterogeneous functional Eunice Santos, (540) 231-6931, [email protected], Parallel and distributed genomic data processing, scientific , computational biology, algorithms, • The Expresso Research Group, a multi-disciplnary group and complexity designing and implementing a system for microarray João Carlos Setubal, (540) 231-9464, [email protected], Bioinformatics, computational biology, genomics, algorithms, combinatorial experiment management optimization • Computational tools for genome annotation and analysis, Cliff Shaffer, (540) 231-4354, [email protected], Problem solving expecially bacterial genomes environments, visualization, data structures and algorithms, user • Investigate the nature and mechanisms of molecular interface design Layne Watson, (540) 231-7540, [email protected], , evolution in the human genome nonlinear programming, fluid mechanics, solid mechanics, image • Design and implement accurate and efficient algorithms processing, parallel computation for molecule structural comparison and molecular docking, Liqing Zhang, (540) 231-9413, [email protected], Computational biology, which is the computational prediction of the three- comparative evolutionary genomics, functional genomics, molecular dimensional structure of binding complexes evolution

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