Anti-MUC5B Monoclonal Antibody, Clone 7G20-F5 (CABT-35479MH) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-MUC5B monoclonal antibody, clone 7G20-F5 (CABT-35479MH) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Mouse monoclonal antibody to Human MUC5B.

Antigen Description This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.

Specificity Non glycosylated domain of mucin MUC5B.

Immunogen Synthetic peptide RNREQVGKF from 4 of the cysteine domains of the tandem repeat region of Human MUC5B conjugated to KLH.

Isotype IgG1, κ

Source/Host Mouse

Species Reactivity Human

Clone 7G20-F5

Purification Protein A purified

Conjugate Unconjugated

Applications ELISA, WB

Sequence Similarities Contains 1 CTCK (C-terminal cystine knot-like) domain.Contains 3 HAT repeats.Contains 3 TIL (trypsin inhibitory-like) domains.Contains 3 VWFC domains.Contains 4 VWFD domains.

Format Liquid

Concentration 1.000 mg/ml

Size 100 μg

Buffer Preservative: NoneConstituents: PBS

Preservative None

Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Gene Name MUC5B mucin 5B, oligomeric mucus/gel-forming [ Homo sapiens ]

Official Symbol MUC5B

Synonyms MUC5B; mucin 5B, oligomeric mucus/gel-forming; MUC5,mucin 5, subtype B, tracheobronchial; mucin-5B; MG1; tracheobronchial; Cervical mucin; Cervical mucin MUC5B; High molecular weight salivary mucin MG1; MG1; MUC-5B; MUC5; MUC5B; MUC5B_HUMAN; MUC9; Mucin 5 subtype B, tracheobronchial; Mucin 5B; Mucin 5B oligomeric mucus/gel forming; Mucin-5 subtype B; Mucin-5B; Sublingual gland mucin; OTTHUMP00000233052; cervical mucin MUC5B; sublingual gland mucin; mucin-5 subtype B, tracheobronchial; mucin 5, subtype B, tracheobronchial; high molecular weight salivary mucin MG1; MUC5; MUC9; MUC-5B;

Entrez Gene ID 727897

Protein Refseq NP_002449

UniProt ID Q9HC84

Chromosome Location 11p15.5

Pathway Salivary secretion, organism-specific biosystem; Salivary secretion, conserved biosystem;

Function extracellular matrix structural constituent; protein binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]