ISSUE 39 SPRING 2013 resource The Newsle2er of Scotland’s Na1onal Academy

Professor Peter Higgs CH FRS FRSE is pictured standing in a life-size model of part of the Large Hadron Collider (LHC) tunnel with some of the LHC researchers and physics students. The model was part of a travelling exhibiton on display at the Sco7sh Parliament in early February. More on back page.

Photograph by Andrew Walker, Sco7sh Parliament

Also featured in this issue: Enlightening the Constitutional Debate New RSE Fellows New Members of the Young Academy of Scotland resource SPRING 2013

Enlightening the Constitutional Debate

On 18 September 2014, the Sco7sh people will Introducing the series, be asked if Scotland should be an independent Professor Sir Adam country. The issue of Sco7sh independence is Roberts, President of the biggest cons5tu5onal issue facing the UK the Bri5sh Academy, at the moment, with far-reaching implica5ons commented: for all UK ci5zens. Our two organisa1ons The Royal Society of Edinburgh (RSE) and the Bri5sh chose to work together Academy (BA) have launched a series of ten events because the Sco3sh to ‘Enlighten the Cons5tu5onal Debate’ in advance referendum planned of this forthcoming referendum on Scotland’s future for Autumn 2014 has rela5onship with the rest of the United Kingdom. implica1ons for all ci1zens in all parts of the The first event in the series, organised by Professor United Kingdom. We see it as our joint responsibility Michael Kea5ng FRSE FBA and held at the RSE in March to ensure that academic exper1se and independent 2013, addressed the issue of Scotland and the EU. perspec1ves are brought to bear on ma2ers of historic The Scotland and the EU event was chaired by importance such as the UK's cons1tu1onal future. journalist Peter Jones, with speakers, Sir John Arbuthno6, President of the Royal Society • Neil Walker FRSE FBA, Regius Chair of Public of Edinburgh, added: Law, University of Edinburgh Scotland’s past, present and future rela1onship • Graham Avery, St. Antony’s College, University with the rest of the United Kingdom will have to of Oxford & European Policy Centre, Brussels be further explored and debated over the next few • Diana Panke, Professor of Poli5cal Science, years, including complex issues such as defence, University of Freiburg educa1on, tax and spending, and rela1ons with Subsequent events in Scotland will be on: the EU. With outstanding academics in the fields of cons1tu1onal law, poli1cs and government, • Defence and Interna5onal Rela5ons; economics, interna1onal rela1ons and history • The Real Economy; among their fellowships, the Bri1sh Academy • Culture & Broadcas5ng; and the Royal Society of Edinburgh are in a • Borders, Immigra5on and Ci5zenship; posi1on to offer first- class scholarly insight • Science and Higher Educa5on; and and academic exper1se on this topic. We hope • Public Services and Welfare. that this series of events will make a useful There will also be three smaller policy forums contribu1on to the debate about Scotland’s in London on: future rela1onship with the rest of the UK. • Tax and Spending; The purpose of the series is not to influence • Monetary Issues; and the referendum process in a par5cular way, • Historical, Legal & Cons5tu5onal Issues. but rather to encourage rich and informed debate A6endance at the London forums will be on a hugely important topic. Reports of the by invita5on only. proceedings will be published a%er each event.

Reports and video recordings of past events and details of events to come are available (and will be regularly updated) at: www.royalsoced.org.uk/1061_EnlighteningtheCons1tu1onalDebate.html

Scotland and the United Kingdom. Full ini5al report produced by the RSE and the BA in September 2012 is available online at: www/rse/org.uk/cms/files/advice-papers/2012/scotland_in_the_UK.pdf

2 resource SPRING 2013

Spreading the benefits of digital participation

In February, the RSE launched its Inquiry into Digital Par5cipa5on in Scotland. The aim of this Inquiry is to ensure that digital technologies help to narrow the social divide, rather than widen it, and that the opportuni5es for economic development presented by digital technologies can be realised across Scotland. The ways we communicate, work, consume, grow our economy, are ac5ve in our communi5es, deliver and access public services, community planning, educa5on and healthcare, are evolving. Digital informa5on and communica5ons technologies are changing the ways we live, work and play, and the pace of change will con5nue; but many individuals, businesses and communi5es are not engaged.

Our Inquiry will focus on communi5es, including social, economic and cultural communi5es, and ask three key ques5ons: • How can digital technologies benefit our communi5es? • What do communi5es, businesses and organisa5ons need to be able to fully par5cipate in this changing society? • How can we ensure that digital technologies help to narrow the social divide, rather than widen it, and that the economic opportuni5es they provide are best realised to support sustainable, flourishing communi5es across Scotland?

The benefits of digital par5cipa5on for individuals, communi5es, public bodies, businesses and voluntary organisa5ons are well documented. Our Inquiry will start by taking stock of social, economic and cultural communi5es across Scotland that are not yet enjoying these benefits to the full. We will engage with these communi5es to understand the barriers to engagement, and develop strategies to overcome them and ensure that the increasingly central role digital technology plays in society contributes to a narrowing of social divides.

Visit the dedicated website and blog and follow progress of the Inquiry at: h2p://engagingdigitalscotland.wordpress.com/

3 resource SPRING 2013

Dr Margaret Anne Craig – Clyde Biosciences Ltd

Dr Margaret Anne Craig Dr Margaret Anne Craig has been interested in science, especially in the human physiology, since she was at high school. She graduated from the University of Glasgow in 1993 with a degree in immunology and pharmacology and con5nued at Glasgow, comple5ng an MSc and then a PhD in 2004 (during which 5me she also had two children). Margaret Anne carried on her research at Glasgow un5l she found out about the RSE/BBSRC Enterprise Fellowship awards programme and successfully submi6ed an applica5on. She commenced her Fellowship in October 2011 and the spin-out company, Clyde Biosciences Ltd, was born.

The RSE/BBSRC Enterprise Fellowship Scheme Dr Craig explains how the Enterprise Fellowship helped her: About Clyde Biosciences Ltd “It gave me a whole year of salary Clyde Biosciences Ltd was founded to commercialise drug toxicity innova5on. It and 5me to work on the business produces both instrumenta5on and biological products which are aimed at the large and nothing else. It provided pharma companies and contract research organisa5ons for drug discovery purposes. business training for 2–3 days a Novel technologies are designed to pick up the preclinical stage toxic effects of drugs month and it was ideal being able screened on normal heart physiology. par5cipate in everything you need All new compounds going through the screening process are tested to ensure that for business: how to set up a they don't upset normal electrophysiology of the heart, or cause arrhythmias business, sales and nego5a5ons, [abnormal rhythms] that could be life threatening. This is not simply for heart drugs. ge7ng investor-ready, and working All drugs – no ma6er their target – are tested this way. and networking with the people who are essen5al to building a Novel compounds will go through extensive preclinical tes5ng, but then at clinical business. trials around 40% fail because of toxicity to the heart. The whole drug discovery process takes 10–12 years and costs around $1.2Bn per drug, but the success rate for “The training was provided by the GO late clinical trials is about 3–5 compounds out of 5–10,000 poten5al drugs, which Group, based in Glasgow as well as at represents a huge expense, especially with late-stage clinical trials. the Royal Society of Edinburgh, which also administers the fellowship scheme. At the early stage there exists the opportunity to remove failures in the process such that they are not taken too far down the development pipeline. Technologies do exist “Lots of people I met then are s5ll to detect cardiac toxicity but they have many limita5ons. helping and guiding me in such ma6ers as intellectual property (IP) and the “We have a novel instrument called CellOPTIQ which op5cally measures true legal side; for example, shareholders transmembrane cardiac electrophysiology in cardiac cells using voltage sensi5ve dyes. agreements. It's a really broad This is a pla4orm that can be used on adult heart cells, animal cells, stem cells – no introduc5on, which was perfect”. other pla4orm exists on the market that can do that. When asked if she had had any “A strength of our system is that normal electrophysiology of single heart cells is very previous interest in business, labour intensive – it needs highly skilled people, is very 5me consuming and the Dr Craig said, “I never knew anything number of tests you can do in a day is very low. We have a long history in Professor about it or thought it was something Godfrey Smith's laboratory at the University of Glasgow, measuring the I'd find myself involved in, but I love it electrophysiology of single cells, and whole hearts. We realised we could apply our and I don't think I could do anything knowledge to design a much needed pla4orm for drug discovery. else now...... “We also write our own so%ware. Ac5on poten5al changes are millisecond events “Now I have a major job to do, in that I and data have to be sampled 20,000 5mes per second. We have so%ware to acquire am se7ng out to build a world-leading and interpret the data, which has been developed by Dr Francis Burton, who is a bioscience company. No easy task!” cardiovascular physiologist as well as an excellent so%ware engineer. “

4 resource SPRING 2013 “A new system to improve drug discovery has won its creator a major entrepreneurship award. Now she aims to build a world-leading bioscience company....” About the Royal Academy of Engineering ERA Founda1on Entrepreneurship Award In June 2012 the RAEng announced: “A cu7ng-edge system to improve the drug discovery process, which could save companies and research ins5tutes significant 5me and cost, as well as improve the probability of success from R&D ac5vi5es, has won its creator a leading engineering entrepreneurship award. “Dr Margaret Anne Craig from Glasgow University scooped the £40,000 Royal Academy of Engineering ERA Founda5on Entrepreneurship Award for her research into new op5cal instrumenta5on, bespoke so%ware and microsystems technologies for evalua5ng new drugs valida5on and tes5ng their toxicity.” Dr Craig a6ended the Royal Academy of Engineering's annual Academy Awards Ceremony at London's Royal Opera House in June 2012. She collected a £10,000 personal prize, and a further £30,000 to invest in the development of her winning idea. The award recognises efforts to extract entrepreneurial promise from academic research, specifically in the field of electro-technology.

[This ar1cle is extracted from a profile feature on Margaret Craig on the BBSRC website 7 January 2013: www.bbsrc.ac.uk/news/people-skills-training/2013/130107-f-profile-margaret-craig.aspx]

The RSE administers funding that supports researchers based in Scotland in many and varied fields. Funding is provided by the Sco7sh Government, BP, Lloyds TSB Founda5on for Scotland and the Caledonian Research Fund, as well as from several bequests and legacies. The programmes through which this funding is made available aim to support Scotland’s cultural, economic and social wellbeing and more specifically to: • a6ract and retain those with outstanding poten5al to establish their Science, Technology, Engineering & Mathema5cs (STEM), as well as Arts & Humani5es careers in Scotland, and to make long-term contribu5ons in these areas and in their applica5on in Scotland; • encourage enterprise and innova5on and the commercialisa5on of technology-based ideas coming from academic research; and • develop interna5onal collabora5ve links and enable par5cipa5on in interna5onal research programmes. Full details of all funding administered by the RSE are available on the website at: www.rse.org.uk/180_FundingAwards.html

5 resource SPRING 2013

Douglas Maxwell – PAL Technologies Ltd

“While convincing demonstra5ons of walking assisted by electrical s5mula5on could be demonstrated in the laboratory,” said Douglas, “it was clear this told us li6le about what people did when they were at home. Did they sit and watch TV all day or get out for a walk?” It became apparent to Douglas that a measure of the benefit of these new mobility enhancing technologies to the pa5ent (although Galvani had first demonstrated ‘animal electricity’ using frog’s legs in 1771) was needed. He began to conceive of a simple measure of what free-living ac5vi5es people got up to, star5ng with the primary ac5vi5es of si7ng, standing and stepping. “I had the germ of an idea for an instrument that I thought would be well received, but had no real idea how to take this forward in business terms,” he said. The opportunity to a6end a night class in entrepreneurship delivered by Dr Jonathan Levie at the University of Strathclyde culminated in Douglas a6ending the University of California’s Summer School in Innova5on and Entrepreneurship in San Diego. On returning, Douglas presented his business case at the launch of the Models demonstra1ng thigh-worn ac1vPAL™ accelerometer (Tom Finnie Photography) Hunter Centre for Entrepreneurship, speaking between Tom Hunter Former Enterprise Fellow Douglas Maxwell discovered his enthusiasm for the human and Tony Blair. condi5on while an undergraduate in the Physiology Laboratory at Glasgow University. A%er gradua5on, he embarked on a peripate5c academic career, in which Winning a pres5gious Royal opportuni5es took him to centres of excellence in Holland and Ireland and, closer Society of Edinburgh Sco7sh to home, both Glasgow and Strathclyde Universi5es. Enterprise Enterprise Fellowship in 2000 allowed Douglas to put While based in the renowned Bioengineering Unit at the University of Strathclyde, his learning into prac5ce. It also Douglas was part of a mul5-disciplinary team specialising in restoring walking abili5es gave him the resources and 5me to people with paralysis. The team worked in close partnership with the Spinal Injuries required to pull together a Unit at Glasgow’s Southern General Hospital and other local and interna5onal clinical funding case jus5fying the centres. commercial poten5al of the From the 1970s, the miniaturisa5on of electronic components had impacted on patent technology and, ul5mately, medicine, resul5ng in the prac5cal development of systems to electronically s5mulate founding PAL (Physical Ac5vi5es paralysed muscles. Logging) Technologies Ltd in 2001.

6 resource SPRING 2013

“The Fellowship Award was really a turning point for me in my career,” said Douglas. “I had enjoyed my academic research opportuni5es but I was less than enthusias5c about lecturing. The short-term contract working dictated by the projects made it difficult to se6le down and, Vancouver apart, the West of Scotland seemed as good a place to se6le as any. Star5ng my own business 5cked all the right boxes and the Fellowship gave me an invaluable insight into the commercialisa5on process. Aided by a mul5-disciplinary group of colleagues from Strathclyde’s Bioengineering Unit, PAL Technologies’ first product was developed.”

First featured on BBC Tomorrow’s World and developed originally for rehabilita5on research, PAL's ac5vPAL™ instruments are typically used by researchers around the The latest version of ac1vPAL™ shown in world who wish to accurately quan5fy a person’s free-living ac5vi5es; i.e., 5me spent charging unit (Tom Finnie Photography) sedentary (si7ng and lying), upright (standing) and ambulatory (walking/running). The ac5vPAL™ is small and lightweight – think of a thin book of matches – and is worn discretely on the thigh for a week, with the pa6ern and intensity of the wearer's physical ac5vi5es being captured and downloaded at the end of the period using custom-designed so%ware. The results are then analysed by researchers inves5ga5ng the correla5on between physical behaviours and chronic disease, in order to provide clinically-relevant evidence to help build healthier lives. In 2005, the ac5vPAL™ won the Nexxus Innova5on Award and, to date, the instrument has featured in over 300 academic journal ar5cles and conference presenta5ons.

A par5cular focus for Douglas in building the business has been his desire to understand his customers’ needs and to work with them to generate genuinely useful solu5ons. This included the development of a Long-Term Ambulatory Monitor (LAM) for prosthe5c limb Receiving Nexxus Innova1on Award manufacturers, Charles A Blatchford from Chris Packard, Nexxus Chair and Sons Ltd, providing both clinician (Tom Finnie Photography) and amputee with an objec5ve measure of prosthe5c limb use over periods of For more informa1on visit: up to 24 months. www.paltechnologies.com Inser1ng the LAM monitor into a prosthe1c limb (photograph University of Strathclyde) This willingness to work closely with customers to deliver RSE Research Awards Currently Available clinically-relevant measures to support and inform RSE/BBSRC Enterprise Fellowships pa5ent-centred treatment approaches has meant that These enable researchers, based across UK Universi5es demand for the Glasgow-based company's core ac5vPAL™ and BBSRC-funded Research Ins5tutes, to commercialise product has con5nued to increase, par5cularly from their research through a one-year programme that researchers in Europe, North America and Australia. includes business training, salary costs and a business “Sta5s5cs such that, on average, every hour si7ng watching development fund. Next deadline: Friday 17 May 2013. television over the age of 25 reduces life expectancy by 22 RSE/STFC Enterprise Fellowships minutes (Veerman et al., Bri1sh Journal of Sports Medicine These enable researchers, based across UK Universi5es, 2011) are really star5ng to have an impact on public health STFC-funded Research Insitutes and CERN, to advance the policy,” Douglas explained, “and much more research is now commercialisa5on of exis5ng research results or being done into the dangers of what has become known as technological developments through a one-year programme the ‘si7ng disease’.” that includes business training, salary costs and a business In response to this, PAL’s latest device, the Ac5vator, pro- development fund. Next deadline: Friday 17 May 2013. vides real-5me feedback to the subject on their sedentary The Interna1onal Exchange Bilateral Programme behaviour by gently reminding them for how long they have This programme supports short-term visits to and from been si7ng. Self-monitoring is a key concept in achieving Scotland, to enhance the research capabili5es of individual behaviour change and research using these new behaviour researchers, develop interna5onal collabora5ve links, and modifica5on tools has already begun. Results of the first enable par5cipa5on in interna5onal research programmes. studies are expected in the Summer of 2013. Next deadline: Friday 31 May 2013. “I have no regrets, but launching and keeping afloat a young Full details of these awards are available at: innova5ve company in Scotland hasn’t always been smooth www.rse.org.uk/635_AvailableNow.html sailing,” smiled Douglas, “as someone once said ‘uncertainty is the price of freedom’.” 7 resource SPRING 2013 RSE Fellows Honoured

The RSE offers its congratula5ons to the following Fellows who recently have been honoured in various ways: In Her Majesty The Queen’s New Year Honours List: Sir Philip Cohen FRS FMedSci was awarded the Medical Research Council's Millennium Medal at a ceremony in the Member of the Order of the Companions of Honour House of Commons in February. The medal is presented Professor Peter Higgs FRS, University of Edinburgh every two years to an outstanding scien5st who has made Knights Bachelor a major contribu5on towards the MRC's goal of improving Professor Ian Diamond FBA, University of Aberdeen human health through medical research. John Leighton, Na5onal Galleries of Scotland Professor Hew Strachan DL, All Souls Oxford Professor Richard Thomson, Watson Gordon Professor of Fine Art at the University of Edinburgh, has been awarded Order of the Bri5sh Empire; Commander (CBE) Officier dans l'Ordre des Arts et des Le6res by the French Dr Magnus Linklater, Columnist and Former Ministry of Culture. Sco7sh Editor, The Times in Scotland Order of the Bri5sh Empire; Officers (OBE) HRH The Duchess of Rothesay was appointed Chancellor Professor John Bu2 FBA, University of Glasgow of the University of Aberdeen in February 2013, Professor David Porteous, University of Edinburgh succeeding former RSE President, Lord Wilson of Tillyorn KT Professor James Prosser, University of Aberdeen GCMG, who stepped down from the role at the end of December. The Very Rev Professor Iain Torrance was Order of the Bri5sh Empire; Member (MBE) appointed to the new post of Pro-Chancellor to enable him Professor Peter Buneman FRS, University of Edinburgh to provide support to The Duchess in her new role. New RSE Fellows 2013

The names of the 47 new Fellows, elected by ballot to the Fellowship in January this year, were announced at an Ordinary Mee5ng of the RSE on 19 March 2013. These Fellows will be formally welcomed to the Society at an Induc5on Ceremony on Monday 20 May. Sir John Arbuthnott said, “Every year the competition for places is intense and this year is no different, so I am delighted to welcome all of these new Fellows to the Royal Society of Edinburgh”. HONORARY FELLOWS CORRESPONDING FELLOWS

COX, Sir David MACMILLAN, David William Cross Honorary Fellow, Nuffield College, University of Oxford James S McDonnell Distinguished University Professor of Chemistry; Chair, Department of Chemistry; DIJKGRAAF, Robbert Henricus Director, Merck Center for Catalysis, Director and Leon Levy Professor, Institute for Advanced Study; Princeton University, USA Past President, Royal Netherlands Academy of Arts and Sciences MUIR, Thomas William Van Zandt Williams, Class of 1965, Professor of Chemistry, TIROLE, Jean Marcel Princeton University, USA Scientific Director, Institut d’Economie Industrielle (IDEI), NDUNG’U, Joseph Mathu Toulouse, France Head of Human African Trypanosomiasis and Other Neglected Diseases Programme, Foundation for Innovative New Diagnostics, Geneva, Switzerland

POOR, Harold Vincent Michael Henry Strater University Professor of Electrical Engineering & Dean of School, Princeton University, USA

VIRLOGEUX, Michel Private Consultant, Bonnelles, France

8 resource SPRING 2013

FELLOWS

BALL, Keith Martin HUGHES, Peter T OBE Scientific Director, International Centre for Mathematical Sciences Former Chief Executive, Scottish Engineering (ICMS); Professor of Mathematics, University of Warwick HUTCHISON, Douglas Chalmers BARRETT, Michael Peter Portfolio Non-Executive Director/Angel Investor Professor of Biochemical Parasitology, University of Glasgow JARDINE, Moira Mary BINGHAM, Robert Professor of Astrophysics, University of St Andrews Professor of Physics, University of Strathclyde; Individual Merit Scientist, Rutherford Appleton Laboratory JENKINS, Gareth Islwyn BLOOMER, Keir Professor of Plant Cell and Molecular Biology, University of Glasgow Independent Education Consultant MACINNES, Allan Iain BRECHIN, Euan Kenneth Professor of Early Modern History, University of Strathclyde Professor of Coordination Chemistry, University of Edinburgh MACLEAN, Margaret Ruth Professor of Pulmonary Pharmacology, Dean of Graduate Studies, BROUN, Dauvit University of Glasgow Professor of Scottish History, University of Glasgow MARCHANT, Ian Derek BROWN, Gordon Douglas Chief Executive, Scottish & Southern Energy Professor of Immunology, University of Aberdeen MILLAR, Andrew John McWalter CAMERON, Peter Duncanson Professor of Systems Biology, University of Edinburgh Professor of International Energy Law and Director of The Centre REID, Elspeth Christie for Energy, Petroleum & Mineral Law & Policy, University of Dundee Professor of Scottish Private Law, University of Edinburgh CAMPBELL, Marion Kay SCHAAP, Pauline Director, Health Services Research Unit, University of Aberdeen Personal Professor of Development Signalling, University of Dundee

CARRUTHERS, Gerard Charles SLOAN, William Taylor Chair of Scottish Literature since 1700 and Deputy Head, Professor of Environmental Engineering, University of Glasgow School of Critical Studies, University of Glasgow STAMPS, Robert Leon Professor of Solid State Physics, University of Glasgow CAWOOD, Peter Anthony Chair in Geology and Head of Department of Earth Sciences, STOW, Dorrik Andrew Vincent University of St Andrews Head of Institute, Institute of Petroleum Engineering, Heriot-Watt Uni- versity; Former Ecosse Chair and Director, Heriot-Watt University DE BORST, Rene SUTHERLAND, Alan James Regius Chair of Civil Engineering and Mechanics, University of Glasgow Professor of Economics, University of St Andrews

FRANK, John William TOUYZ, Rhian Merry Director, Scottish Collaboration for Public Health Research and Policy, Director, Institute of Cardiovascular and Medical Sciences, Centre for Population Health Sciences, University of Edinburgh University of Glasgow VIJAYAKUMAR, Sethu GARDEN, Olivier James Professor of Robotics and Director, IPAB, University of Edinburgh Regius Professor of Clinical Surgery, University of Edinburgh; Honorary Consultant, NHS Lothian WADDELL, John McLaren Ogilvie Chief Executive, Archangel Informal Investments GILLESPIE, Iain Miles Macgregor WALL, Ian James Professor, ESRC Innogen Centre, University of Edinburgh Chair, Science and Engineering Education Advisory Group

GOULSON, David WAUGH, Robbie Professor of Biological Sciences, University of Stirling Principal Investigator, The James Hutton Institute WEBB, Robert HANSON, Vicki Lynne Chief Executive and Principal, SRUC – King’s Buildings Campus, Professor of Inclusive Technologies, University of Dundee Edinburgh WYATT, Paul Graham HEGERL, Gabriele Clarissa Professor of Drug Discovery, Head of Drug Discovery Unit, Professor of Climate System Science, University of Edinburgh University of Dundee

9 resource SPRING 2013

Monday 15 April 2013 FULLJDAY CONFERENCE The Interna1onal Launch of HCR:V3 This joint one-day conference is hosted by The Royal Society of Edinburgh and organised by Violence Risk Assessment Training. It marks the interna5onal launch of Version 3 of the HCR–20. The HCR–20 is the premier approach to the evalua5on of violence risk. This procedure is evidence-based. It has been evaluated in 32 different countries and there are currently 18 Monday 22 April 2013 at 6 pm transla5ons. The last edi5on was published in 1997. PART OF THE EDINBURGH LECTURES SERIES Following a comprehensive interna5onal research endeavour, the new edi5on, Dr John Rae – Forgo2en Arc1c Hero? HCR:V3, is about to be launched. The authors have chosen to launch the new Ken McGoogan version in Edinburgh prior to the annual The award-winning author of ten books, Violence Risk Training Workshops. Ken McGoogan is best known for Fatal Scotland is recognised as a centre of Passage: The Untold Story of John Rae, excellence for evidence-based approaches the Arc1c explorer who discovered the to these problems. The MacLean fate of Franklin. That work won literary Commi6ee on Serious Violent and Sexual awards in Canada and the United States, Offenders established a new approach and became the basis of an acclaimed to the assessment of violence which has docudrama called Passage (BBC Scotland). been recognised interna5onally. Ken recently published How the Scots The authors of the new HCR:V3, Invented Canada, a Canadian bestseller. Professor Christopher Webster, Professor He writes a column for Canada’s History Stephen Hart and Dr Kevin Douglas, will magazine and teaches an online wri5ng all describe the research base of the course through the University of Toronto. new instrument and its u5lity in the Last August, he revisited the loca5on in the High Arc5c where, in 1999, he erected prac5ce of violence risk assessment. a plaque to mark the spot where Sco7sh explorer John Rae discovered the final Full rate: £150 link in the Northwest Passage. (Ken McGoogan pictured above at the plaque). Fellows/Academics: £75* Everyone is welcome to our lectures, but please note that you must prebook a Student/Concession: £50* 5cket through the Usher Hall Box Office. Price £5 – (refundable up to three days *limited places available prior to lecture (personal callers only)). To register, visit the website: There is a £1 nonrefundable transac5on fee for telephone and online bookings. www.violenceriskassessment.com/ Online: www.usherhall.co.uk For more informa5on In person: Usher Hall Box Office, Lothian Road, Edinburgh EH1 2EA phone: 01355 244 966 or email: or telephone: 0131 228 1155 [email protected] Monday–Friday 10am–5.30pm

10 Tuesday 30 April 2013 at 6 pm Monday 24 June 2013 at 6 pm LECTURE LECTURE From Gannets to Pandas – Vaccines to Prevent 100 Years of Progress at and Treat Cancer Edinburgh Zoo Professor Ian Frazer AC FRS CEO and Director of Research, Chris West, CEO, Royal the Transla5onal Research Ins5tute, Zoological Society of Scotland Brisbane, Australia

Virus infec5ons are responsible for about one in five human cancers. In his lecture, Professor Frazer will discuss how this knowledge has been used to develop vaccines for the preven5on of cervical cancer, and how they have been shown to be effec5ve. The challenge is to see them used in the developing world, where the majority of cervical cancers occur. In 2013, Edinburgh Zoo will be 100 years old. There is This is a joint lecture with the Sco7sh Cancer jus5fiable pride in achievements that echo the evolu5on Founda5on, supported by the Cruden Founda5on. of zoos globally. This lecture forms part of an RSE Ordinary Mee5ng New CEO, Chris West, is a highly respected and experienced and so will be preceded by Society business, such vet and conserva5onist with interna5onal experience. as Fellows signing the Roll. He will reflect on future challenges and diverse ac5vi5es of zoos as they conduct scien5fic field programmes and RSE Lectures and Discussions forums are open to all educa5on outreach in addi5on to breeding endangered and normally free to a6end, but registra5on is required. species – and running major visitor a6rac5ons. To register, please contact the Events Team – 0131 240 2780 In a world that is increasingly crowded, warming and – [email protected] or visit www.rse.org.uk/events/ damaged, the role of zoos is even more relevant as ‘refugee Events o%en run to capacity, so if you are unable to a6end camps’ and as centres for environmental awareness. an event you have booked, please inform the Events Team so that your 5cket can be reallocated.

11 resource SPRING 2013

2013 Spring Masterclasses Twice a year, the RSE and partner universi5es deliver a series of free Science Masterclasses across Scotland. At these Masterclasses, S1 and S2 students get up to all sorts of scien5fic mischief and mayhem, dissec5ons and designs, crea5ng things from bagpipes to perfume and breaking down plant DNA, exploring the bug world around us, learning how to design things, from planes to bridges, and even indulging in a round of chemical cluedo! The Spring 2013 Masterclasses are now taking place, running across four consecu5ve Saturdays during March, April and May, being held in Glasgow, Edinburgh, St Andrews and Dundee. Topics covered in this session are: Glasgow University How to be a Bridge Builder – Joanna Cholewa How to be an Astrophysicist – Lewis Mackenzie How to be an Aeroplane Designer – Peter Murray How to be a Rocket Scien1st – Alasdair Wilson Dundee University The Ma1ng Game – Asser1ve Ma1ng in Humans – Dr S Hubbard The Genome Detec1ves – Dr D Booth and Dr D Mar5n The Magical and Mysterious World of Chemistry – Dr N Brewer Be a Hogwart’s Wizard Grader – Dr L Morris Heriot-Wa6 University DNA Extrac1on using Kitchen Chemistry – Dr Lynn Paterson Chemical Cluedo – Dr Magnus Bebbington Mystery of Magne1sm – Dr Bill MacPherson Gizmo Lab – Dr Jim Herd St Andrews University Bagpipes and Electronics – Bruce Sinclair Chemical Cluedo – Dr Sharon Ashbrook It’s a Wonderful Life – Ruth Robinson and Stuart Allison Marine Biodiversity – Rebecca Aspden

All of the above speakers are experts in their fields, covering a range of subject areas. Many are willing to work with the teachers to tailor their talks to areas most relevant to class curriculums, and to different age-groups and class sizes. We are grateful to each of them for the 5me and effort they give in providing these talks on behalf of the RSE.

For full details on this series of masterclasses and other informa5on about our Schools Programme, visit our website at: www.rse.org.uk/707_SchoolsEvents.html or contact Events Officer Rachel Steele, tel: 01312405035; email: [email protected]

12 resource SPRING 2013

This programme of high-quality ac5vi5es for young people and the public is currently taking place across the region of Lochaber. The varied programme of inspira5onal educa5onal talks, discussion forums and workshops for school-aged children and the wider public will run un5l June 2013. The RSE @ Lochaber ini5a5ve follows similar successful RSE projects in Arbroath (2008/2009) and the Dumfries and Galloway region (2010/2011). As Scotland’s Na5onal Academy, it is the role of the Royal Society of Edinburgh ac5vely to promote the educa5on of young people throughout Scotland, and it aims to s5mulate and develop interest in science, society, culture and the arts across all age groups. Whilst the programme is designed to appeal to all age groups, one key aim of the RSE@ ini5a5ves is to enhance the understanding and apprecia5on that school children have of their local community by encouraging a sense of belonging to an area rich in cultural and human resources. The programmes draw on the Place Names – Professor Jeremy Smith • Appin Murder Project exper5se of the RSE’s highly • Glencoe Primary School • Event on Canna dis5nguished Fellows and other • Duror Primary School • Primary Workshops – delivered experts from a variety of disciplines. • Ben Nevis Hotel, Fort William by members of RSE staff. • Kilchoan Primary School • The Sco7sh Associa5on of Marine Below is a list of some of the events • Kilchoan (West Highland College) Science (SAMS) has offered to that are being organised over the deliver workshops for primary next two months. Most of the talks June schools – these would be seabed will be presented to school pupils Feeding Nine Billion People – mapping workshops, focusing on during the day and repeated at night Professor Maggie Gill FRSE the Loch Linnhe area and providing for the general public. (NB: Details • Lochaber High School an overview of general and seabed have not all been finalised, so what • Ben Nevis Hotel, Fort William mapping and techniques and uses is shown is subject to change). Making Scotland’s Landscape – for these maps. These could also May Professor Iain Stewart include some work on marine life in Gaelic Culture of Lochaber – • Lochaber High School the area by showing habitat maps. Professor Hugh Cheape and • Ben Nevis Hotel, Fort William This could be adapted for older Professor Donald Meek FRSE pupils, focusing on the careers • The Sunart Centre (Ardnamurchan involved in SAMS seabed mapping High School), Stron5an In addi5on to these events, other projects, expanding to cover other Women In Science – Antarc1ca – ideas are currently ‘in the pipeline’. careers available through SAMS and Alison McLure, Ins5tute of Physics (IoP) • The Sco7sh Book Trust has granted providing an insight into the SAMS • Kinlochleven High School (to coincide funding for five sessions of story degree course in marine science. with the IoP’s ‘Lab in a Lorry’ visit) telling/author visits. Contact has • Lochaber High School (to coincide been made with Lochaber libraries The RSE@Lochaber Programme runs un1l June 2013. For details of events visit: with the IoP’s ‘Lab in a Lorry’ visit) to host these events and interest www.rse.org.uk/1007_RSELochaber.html has been expressed. Lochaber – Bandit Country or Jacobite Summary reports of all the talks are • Dragons’ Den – Kinlochleven, Stronghold? – Professor Allan available at: Ardnamurchan and Lochaber High Mcinnes www.rse.org.uk/506_PastEventsReports.html Schools have expressed interest. • The Sunart Centre, Stron5an

13 resource SPRING 2013

The RSE Young Academy of Scotland was pleased to announce the appointment of 50 new members. They will join the 68 exis5ng members from 1 April 2013. Almost two hundred applica5ons were received for membership. These were considered by a panel including RSE Fellows and members of the exis5ng Young Academy. The new members, 26 women and 24 men, range in ages from 28 to 43. Prac55oners and academics are represented and a variety of subject areas are covered, including: photography; government; archaeology; astrobiology; robo5c systems; obesity; and human rights.

Chris O’Sullivan, one of the four Young Academy co-chairs commented, FROW, Emma I speak for all members of the Young Academy in welcoming the successful Lecturer, University of Edinburgh applicants. The new members are based in ins1tu1ons and organisa1ons across Science/social science policy development Scotland, and come from a range of disciplines. The quality of applica1ons was HAGENDORFF, Jens extremely high, from both academic and professional fields, and it is exci1ng to Professor, University of Edinburgh see the Young Academy growing. Governance & regula5on of financial ins5tu5ons Over the past eighteen months, the Young Academy has developed work streams in health, educa1on, equality and cons1tu1onal reform; areas in which many HAMILTON, Andrea applicants felt they had a contribu1on to make. NERC Research Fellow, University of Edinburgh Physical sciences applied to material We look forward to the added value that the new members will bring to the work conserva5on programmes we have, and to the new ideas and experiences they will contribute. HARKNESS, Patrick George Lecturer, University of Glasgow For more informa1on and latest news of the Young Academy of Scotland, Space systems engineering/deployable systems visit the website at: www.youngacademyofscotland.org.uk/ HEVIA, Eva Reader/Royal Society Research Fellow, University of Strathclyde ANTIZAR?LADISLAB, Blanca DALGLISH, Christopher James Mixed metal chemistry Senior Lecturer, University of Edinburgh Lecturer, University of Glasgow Environmental engineering Archaeology HILD, Stefan BELL, Donna DEWAR, Michaela Tanya Lecturer, University of Glasgow Head of Early Years Quality Improvement Unit, Research Fellow, University of Edinburgh Detec5on of gravita5onal waves Sco7sh Government Neuropsychology/memory impairment HUTCHINSON, Sharon June Early years policy DOHERTY, Mary Kathleen Professor, Glasgow Caledonian University BISBY, Luke Graham Lecturer, University of the Highlands Public health/addic5ons and health inequali5es Professor, University of Edinburgh and Islands JONES, Christopher Stuart Fire safety engineering Mass spectrometry/proteomics Senior Lecturer, University of St Andrews BOCK, Adam DWECK, Marc Richard Middle English language and literature Lecturer, University of Edinburgh Lecturer/BHF Clinical Fellow, KAGANSKY, Alexander Entrepreneurship/commercialisa5on University of Edinburgh Programme Leader, MRC Human Gene5cs Unit, Cardiology BRIDLE, Helen Louise University of Edinburgh RAEng/EPSRC Research Fellow, ELLISON, Sophie Jane Epigene5cs Heriot-Wa6 University Senior Consultant, Blake Stevenson Ltd KEHOE, Sara Karly Water monitoring Social research Lecturer, Glasgow Caledonian University BROMILEY, Geoffrey David FAIRLEY, Elizabeth Anne Religiosity, na5onal iden5ty, ethnicity in the Lecturer, University of Edinburgh Scien5fic Consultant Bri5sh world Deep-earth geology EFB Services KELLY, Tobias CALDWELL, Chris1ne Anna FERGUSON, Heather Margaret Reader, University of Edinburgh Senior Lecturer, University of S5rling Lecturer, University of Glasgow Human rights, humanitarianism and poli5cal Social learning & cultural evolu5on Infec5ous disease ecology/malaria violence CAZIN, Catherine Suzanne Julienne FORGAN, Duncan Hugh KOZLOVA, Olga Royal Society Research Fellow, Post-doc Research Fellow, Enterprise Crea5on Manager,Heriot-Wa6 University of St Andrews University of Edinburgh University, Enterprise development/business Organic & inorganic synthe5c chemistry Astrophysics & astrobiology development, commercialisa5on

14 resource SPRING 2013

KRISTENSSON, Per Ola O’ROURKE, Bernade2e SKAFIDA, Valeria SICSA Lecturer. EPSRC Research Fellow, Lecturer, Heriot-Wa6 University Bri5sh Academy Post-doc Research University of St Andrews Role of language in social difference & inequality Fellow, University of Edinburgh Health and food inequali5es in Scotland Human–computer interac5on technologies PATTON, Elizabeth LALLI, Gurjit Singh MRC Human Gene5cs Unit. Programme SMITH, Stewart Leader, Medical & Developmental Gene5cs, Director, Power of Youth RCUK Academic Fellow/Lecturer University of Edinburgh University of Edinburgh Event organisa5on/ development and Melanoma/drug development communica5on of ideas Biomedical engineering PERKINS, Kate SMITH, David LOGUE, Jennifer Private Secretary, Sco7sh Government Teaching Fellow, University Clinical Senior Lecturer/ CSO/NES Clinician Administra5on/management Scien5st Fellow, Glasgow BHF of Aberdeen RAMAMOORTHY, Subramanian Cardiovascular Research Centre Educa5on policy Lecturer, University of Edinburgh Obesity, metabolic medicine Intelligent and autonomous robo5c systems TETZLAFF, Doerthe MACDONALD, Malcolm Professor, University of Aberdeen RUTZ, Chris1an Catchments and river systems Deputy Head of Department, Reader/BBSRC David Phillips Fellow, University of Strathclyde University of St Andrews TIMMING, Andrew Richard Space technology, UK space policy Tool use in non-human animals Reader, University of St Andrews defini5on SCHWAN, Anne Employee involvement and MACKENZIE, Simon Ross Maclean Reader, Edinburgh Napier University par5cipa5on Professor, University of Glasgow History of crime and punishment/Literary UNCITIT?BROCETA, Asier Transna5onal crime, white-collar crime, study in present-day prisons IGMM Academic Fellow. organised crime, policing University of Edinburgh, MCNEILL, Fiona Jennet Edinburgh Cancer Research Research Fellow, University UK Centre of Edinburgh Chemical biology, medicinal chemistry Ar5ficial intelligence VIDAL, Marcos MERSINIS, Michail Group Leader, Lecturer. Ar5st/Glasgow School of Art Beatson Ins5tute for Cancer Research Fine art/photography Cancer metastasis NAUMANN, Ingela Kris1na WOOD, Tiffany Anne2e Lecturer, University of Edinburgh Industrial Research Liaison, Edinburgh Early-years policy and educa5on Complex Fluids Partnership governance in welfare states First cohort of Young Academy in debate in 2011 So% ma6er physics

FRIENDS OF THE SOCIETY CORPORATE PARTNERS OF THE ROYAL SOCIETY OF EDINBURGH

If you would like to know more about the Royal Society of Edinburgh’s Friends of the Society initiative, or if your organisation may be interested in joining the scheme, please contact: Gordon Adam, Director of Business Development and Communications – 0131 240 2781 – [email protected]

15 resource SPRING 2013

Visit by President of the Institute of Electrical and Electronics Engineers (IEEE)

In January 2013, the President of the IEEE, Dr Peter Staecker, visited the RSE. The IEEE and the RSE, with funding from Wolfson Microelectronics plc, award an annual joint prize to recognise groundbreaking contribu5ons that have had an excep5onal impact on the development of electronics and electrical engineering or related fields, the IEEE/RSE/Wolfson, James Clerk Maxwell Award.

Pictured right (l–r) Sir John Arbuthno6, President of the RSE, Dr Staecker and Dr David Milne, Chairman of the James Clerk Maxwell Founda5on Dr Staecker is pictured (above le%) with Professor Higgs and Sir John at the From Maxwell to Higgs Exhibi5on currently on display in the RSE Upper Gallery. The LHC visits the Scottish Parliament

A travelling exhibi5on showcasing the Large Hadron Collider (LHC), the world’s largest science experiment, was on public display in the Main Hall of the Sco7sh Parliament from 2nd to 8th February 2013. Visitors were able to walk through a life-size model of part of the LHC tunnel and learn more about science from interac5ve exhibits. The exhibi5on helped create a sense of what it's like to be a par5cle physicist working on the largest science experiment of our genera5on. Visitors also had the opportunity to meet some of the UK's top LHC researchers and physics students who are working at the LHC. The Large Hadron Collider (LHC) is the most powerful par5cle accelerator ever built, its 27-km circular course lying 100 m below the ground at the European par5cle physics laboratory CERN, near Geneva in Switzerland. Professor Peter Higgs CH FRS FRSE (centre) beside the life-size CERN is dedicated to the pursuit of fundamental science. model of the LHC, with Chief Execu5ve of STFC, John Womersley (right) Through the Science and Technology Facili5es Council’s and Deputy Presiding Officer, John Sco6 MSP (STFC) subscrip5on, the UK is one of the biggest investors In recogni5on of his outstanding work that led in CERN and, through its membership, UK companies can to these findings, Professor Higgs was awarded bid for high-tech contracts. In addi5on, UK scien5sts, a specially-commissioned medal by the RSE in with funding from STFC, have contributed vital hardware, October 2012 and named a Member of the compu5ng and exper5se to the LHC. Order of the Companions of Honour in Her Majesty Professor Peter Higgs first suggested the existence of The Queen’s New Years Honours List 2013 (page 8). a par5cle crucial for understanding why objects in the He was also awarded the 2013 Edinburgh Medal universe have mass – subsequently named the Higgs boson jointly with CERN. In March 2013, Professor Higgs – in 1964 and on 4 July 2012, CERN announced the discovery and Professor Rolf-Dieter Heuer, Director General of a new par5cle, consistent with the Higgs boson. In the of CERN, delivered the Edinburgh Medal Address months following, physicists grew increasingly confident in the Signet Library, Edinburgh, when the Medal that the ‘Higgs-like’ par5cle discovered then, actually is was presented, at the beginning of the Edinburgh the long-sought Higgs boson. Interna5onal Science Fes5val 2013. COPY ADDRESS INFORMATION Please send any copy to the Editor (Jenny Liddell) 22–26 GEORGE STREET website: www.royalsoced.org.uk at the Society – [email protected] EDINBURGH, SCOTLAND www.rsescotlandfoundation.org.uk ReSourcE: ISSN No 1473-7841 EH2 2PQ e-mail: [email protected] Any opinions expressed in this newsletter are not necessarily those of all RSE Fellows Tel: 0131 240 5000 Fax: 0131 240 5024 The Royal Society of Edinburgh, Scotland’s National Academy, is Scottish Charity No. SC000470 The RSE Scotland Foundation is a connected charity, registered in Scotland as Scottish Charity No. SC024636 Events ticketline: 0131 240 2780 The RSE Scotland SCIO is a connected charity, registered in Scotland as Scottish Charity No. SC043194