bioRxiv preprint doi: https://doi.org/10.1101/2020.05.03.075382; this version posted May 4, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY 4.0 International license. 1 Spatiotemporal contribution of neuromesodermal progenitor-derived neural cells in the 2 elongation of developing mouse spinal cord 3 Running title: NMPs generate mouse spinal cord. 4 Mohammed R Shaker1+, Ju-Hyun Lee1, Kyung Hyun Kim2,3, Veronica Jihyun Kim3, Joo Yeon 5 Kim1, Ji Yeoun Lee 2,3, Woong Sun1* 6 1 Department of Anatomy and Division of Brain, Korea 21 Plus Program for Biomedical 7 Science, Korea University College of Medicine, 73, Inchon-ro, Seongbuk-gu, Seoul 02841, 8 Republic of Korea. 9 2 Division of Pediatric Neurosurgery, Pediatric Clinical Neuroscience Center, Seoul National 10 University Children’s Hospital, Seoul National University College of Medicine, 101 Daehakro, 11 Jongno-gu, Seoul, 110-769, Republic of Korea. 12 3 Neural Development and Anomaly Laboratory, Department of Anatomy and Cell Biology, 13 Seoul National University College of Medicine, 101 Daehakro, Jongno-gu, Seoul, 110-769, 14 Republic of Korea. 15 +Current address: Australian Institute for Bioengineering and Nanotechnology (AIBN), The 16 University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia. 17 18 *Corresponding author: 19 Woong Sun, PhD 20 Professor, Department of Anatomy 21 Brain Korea 21 Program, 22 Korea University College of Medicine, 23 Seoul, 02841, Korea 24
[email protected] 25 26 bioRxiv preprint doi: https://doi.org/10.1101/2020.05.03.075382; this version posted May 4, 2020.