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Pharmacology at the University of Sydney: a Brief History
PHARMACOLOGY AT THE UNIVERSITY OF SYDNEY: A BRIEF HISTORY Rudiments of pharmacology were first taught in of appointment be made to Adrien Albert (who was 1883 in the newly-founded medical school, whose later to become Professor of Medicinal Chemistry degrees of Bachelor of Medicine and Doctor of at the Australian National University). The offer of Medicine were established by Royal Charter in the Chair was declined, so the position was 1858. The discipline was described as Materia advertised, attracting thirteen applications, but was Medica, and its first lecturer was Thomas Storie then re-advertised at new salary rates in the hope Dixson, from 1883 to 1917. The establishment of of increasing the number of applicants. Meanwhile, a Chair of Pharmacology was then recommended, Dr Hales Wilson, another distinguished medical and, in 1918 the first Professor of Pharmacology, graduate of the University, was appointed to Henry George Chapman, was appointed. lecture in Pharmacology. Hales Wilson gave one Chapman had taught in the Department of lecture per week for one term in each of two years Physiology but was not a specialist in to medical students, largely ex-service personnel, pharmacology; he resigned to become Professor who were described as 'very likeable and keen to of Physiology in 1920. The Chair of Pharmacology learn'. then lapsed for twenty-eight years. The previous position of Lecturer in Materia Medica was re- Roland Thorp and the Department of established, and filled in 1921 by John Pharmacology MacPherson, a Sydney graduate who was a leading Australian authority on Materia Medica and Roland Thorp was selected from the therapeutics. -
Comprehensive Analysis of Different Contemporary Barley Genotypes Enhances and Expands the Scope of Barley Contributions to Beer Flavor
Journal of the American Society of Brewing Chemists The Science of Beer ISSN: (Print) (Online) Journal homepage: https://www.tandfonline.com/loi/ujbc20 Comprehensive Analysis of Different Contemporary Barley Genotypes Enhances and Expands the Scope of Barley Contributions to Beer Flavor S. Windes , H. M. Bettenhausen , K. R. Van Simaeys , J. Clawson , S. Fisk , A. L. Heuberger , J. Lim , S. H. Queisser , T. H. Shellhammer & P. M. Hayes To cite this article: S. Windes , H. M. Bettenhausen , K. R. Van Simaeys , J. Clawson , S. Fisk , A. L. Heuberger , J. Lim , S. H. Queisser , T. H. Shellhammer & P. M. Hayes (2020): Comprehensive Analysis of Different Contemporary Barley Genotypes Enhances and Expands the Scope of Barley Contributions to Beer Flavor, Journal of the American Society of Brewing Chemists To link to this article: https://doi.org/10.1080/03610470.2020.1843964 © 2020 The Author(s). Published with View supplementary material license by Taylor & Francis Group, LLC Published online: 01 Dec 2020. Submit your article to this journal View related articles View Crossmark data Full Terms & Conditions of access and use can be found at https://www.tandfonline.com/action/journalInformation?journalCode=ujbc20 JOURNAL OF THE AMERICAN SOCIETY OF BREWING CHEMISTS https://doi.org/10.1080/03610470.2020.1843964 Comprehensive Analysis of Different Contemporary Barley Genotypes Enhances and Expands the Scope of Barley Contributions to Beer Flavor S. Windesa , H. M. Bettenhausenb , K. R. Van Simaeysc, J. Clawsonc, S. Fiska , A. L. Heubergerb , J. Limc , S. H. Queisserc , T. H. Shellhammerc , and P. M. Hayesa aOregon State University, Department of Crop and Soil Science, Corvallis, OR, U.S.A.; bColorado State University, Horticulture and Landscape Architecture, Fort Collins, CO, U.S.A.; cOregon State University, Department of Food Science and Technology, Corvallis, OR, U.S.A. -
Painel 229|PN.229
Painel 229|PN.229 12 a 17/Nov, 2017, Águas de Lindóia/SP, Brasil DFT study of the self-aggregation of asphaltene model compounds Kassem K. Negea(IC), Mateus R. Lageb(PQ), Stanislav R. Stoyanovc,d(PQ), José W. de M. Carneiroa(PQ) aInstituto de Química, UFF, Outeiro de São João Batista s/n, Centro, Niterói, RJ, 24020-141, Brazil bUniversidade Federal do Maranhão, Campus Balsas, Rua José Leão, 484, Centro, Balsas, MA, 65800-000, Brazil c Natural Resources Canada, Canmet ENERGY-Devon, 1 Oil Patch Drive, Devon, Alberta T9G 1A8, Canada d Department of Chemical and Materials Engineering, University of Alberta, Edmonton, Alberta T6G 2 V4, Canada Abstract: Asphaltenes are compounds found in the heavier fractions of the oil as a supramolecular aggregates [1]. The chemical complexity of these fractions of oil creates difficulties for their understanding and the prediction of their behavior. However, many authors have performed studies related to their chemical structure and properties, proposing molecules as asphaltene models, mainly based on data obtained by nuclear magnetic resonance (NMR), elemental analysis and molecular weight [2]. Asphaltenes can cause serious problems in oil exploration, triggered mainly to their deposition that is due to the level of molecular aggregation. The problems caused by the deposition of asphaltenes are present from the exploration to the refining of the petroleum. Thus, it is extremely important to know the mechanisms of aggregation of asphaltenes. In this work, we performed a theoretical study of the homodimerization and self- aggregation of asphaltene model compounds A and B (Figure 1). These model compounds contain fused aromatic rings and heterocyclic fragments representative of asphaltenes tethered with butyl linkers to represent archipelago asphaltenes [3]. -
Thermal Hydraulics Analysis of the Distribution Zone in Small Modular Dual Fluid Reactor
metals Article Thermal Hydraulics Analysis of the Distribution Zone in Small Modular Dual Fluid Reactor Chunyu Liu 1,* , Xiaodong Li 1 , Run Luo 1,2 and Rafael Macian-Juan 1 1 Chair of Nuclear Technology, Department of Mechanical Engineering, Technical University of Munich (TUM), Boltzmannstr. 15, 85748 Garching, Germany; [email protected] (X.L.); [email protected] or [email protected] (R.L.); [email protected] (R.M.-J.) 2 School of Resource & Environment and Safety Engineering, University of South China, No. 28, Changsheng West Road, Hengyang 421001, China * Correspondence: [email protected] or [email protected] Received: 29 June 2020; Accepted: 4 August 2020; Published: 6 August 2020 Abstract: The Small Modular Dual Fluid Reactor (SMDFR) is a novel molten salt reactor based on the dual fluid reactor concept, which employs molten salt as fuel and liquid lead/lead-bismuth eutectic (LBE) as coolant. A unique design of this reactor is the distribution zone, which locates under the core and joins the core region with the inlet pipes of molten salt and coolant. Since the distribution zone has a major influence on the heat removal capacity in the core region, the thermal hydraulics characteristics of the distribution zone have to be investigated. This paper focuses on the thermal hydraulics analysis of the distribution zone, which is conducted by the numerical simulation using COMSOL Multiphysics with the CFD (Computational Fluid Dynamics) module and the Heat Transfer module. The energy loss and heat exchange in the distribution zone are also quantitatively analyzed. The velocity and temperature distributions of both molten salt and coolant at the outlet of the distribution zone, as inlet of the core region, are produced. -
Hemistry N E W S L E T T E R
University of Michigan Chemistry N E W S L E T T E R Letter from the Chair I am pleased to send greetings and to fullerene, was a very engaging keynote Contents highlight the activities of the Chemistry speaker for this event. Before his talk, the Department this past year. The Depart- Department was awarded a 2006 Citation Letter from the Chair ........................ 1 ment is continuing to make enormous for Chemical Breakthroughs from the Di- New Faculty ..................................... 3 strides towards accomplishing its goal of vision of the History of Chemistry of the becoming one of the top Chemistry De- American Chemical Society in recognition Faculty News.................................... 4 partments in the nation. The most recent of work by Moses Gomberg. Additionally, I 150th Birthday ...................................4 US News and World Report ranking of have enjoyed meeting departmental alumni Graduate Program News Chemistry Departments listed Michigan and alumnae as well as prospective faculty as 16th in the nation; the analytical cluster candidates at the University of Michigan Graduate Awards .......................... 7 was ranked 9th, biochemistry 13th, organic reception that is held at every American Graduate Degrees........................ 10 th th 13 , and inorganic 15 . These are the Chemical Society National meeting. Please GS Council News .........................12 highest rankings for these clusters in many plan on attending this reception at the next years. We anticipate that our standing in ACS meeting. Undergraduate Program News the community will continue to rise, in REU Program ...............................12 Over the past year the department has view of the tremendous success that we recruited Dr. Anne McNeil, an outstand- Undergraduate Awards ............... -
Novel Triadius-Like N4 Specie of Iron Nitride Compounds Under High
www.nature.com/scientificreports OPEN Novel triadius-like N4 specie of iron nitride compounds under high pressure Received: 11 May 2018 Yuanzheng Chen1, Xinyong Cai1, Hongyan Wang1, Hongbo Wang2 & Hui Wang2 Accepted: 2 July 2018 Various nitrogen species in nitrides are fascinating since they often appear with these nitride as Published: xx xx xxxx superconductors, hard materials, and high-energy density. As a typical complex, though iron nitride has been intensively studied, nitrogen species in the iron–nitrogen (Fe-N) compounds only have been confned to single atom (N) or molecule nitrogen (N2). Using a structure search method based on the CALYPSO methodology, unexpectedly, we here revealed two new stable high pressure (HP) states at 1:2 and 1:4 compositions with striking nitrogen species. The results show that the proposed FeN2 stabilizes by a break up of molecule N2 into a novel planar N4 unit (P63/mcm, >228 GPa) while FeN4 stabilizes by a infnite 1D linear nitrogen chains N∞ (P-1, >50 GPa; Cmmm, >250 GPa). In the intriguing N4 specie of P63/mcm-FeN2, we fnd that it possesses three equal N = N covalent bonds and forms a perfect triadius-like confguration being never reported before. This uniqueness gives rise to a set of remarkable properties for the crystal phase: it is identifed to have a good mechanical property and a potential for phonon-mediated superconductivity with a Tc of 4–8 K. This discovery puts the Fe-N system into a new class of desirable materials combining advanced mechanical properties and superconductivity. Nitrogen (N) is the most abundant element in the earth’s atmosphere and is one of the least studied elements regarding the composition of the Earth1. -
小型飛翔体/海外 [Format 2] Technical Catalog Category
小型飛翔体/海外 [Format 2] Technical Catalog Category Airborne contamination sensor Title Depth Evaluation of Entrained Products (DEEP) Proposed by Create Technologies Ltd & Costain Group PLC 1.DEEP is a sensor analysis software for analysing contamination. DEEP can distinguish between surface contamination and internal / absorbed contamination. The software measures contamination depth by analysing distortions in the gamma spectrum. The method can be applied to data gathered using any spectrometer. Because DEEP provides a means of discriminating surface contamination from other radiation sources, DEEP can be used to provide an estimate of surface contamination without physical sampling. DEEP is a real-time method which enables the user to generate a large number of rapid contamination assessments- this data is complementary to physical samples, providing a sound basis for extrapolation from point samples. It also helps identify anomalies enabling targeted sampling startegies. DEEP is compatible with small airborne spectrometer/ processor combinations, such as that proposed by the ARM-U project – please refer to the ARM-U proposal for more details of the air vehicle. Figure 1: DEEP system core components are small, light, low power and can be integrated via USB, serial or Ethernet interfaces. 小型飛翔体/海外 Figure 2: DEEP prototype software 2.Past experience (plants in Japan, overseas plant, applications in other industries, etc) Create technologies is a specialist R&D firm with a focus on imaging and sensing in the nuclear industry. Createc has developed and delivered several novel nuclear technologies, including the N-Visage gamma camera system. Costainis a leading UK construction and civil engineering firm with almost 150 years of history. -
Nuclear Reactors' Construction Costs
Nuclear reactors’ construction costs: The role of lead-time, standardization and technological progress Lina Escobar Rangel and Michel Berthélemy Mines ParisTech - Centre for Industrial Economics CERNA International WPNE Workshop Project and Logistics Management in Nuclear New Build NEA Headquarters - Issy les Moulineaux, 11th March 2014 Growing demand for nuclear power... Demand for nuclear power has increased in the past years and it is likely to keep on rising. Experienced countries: US, UK, Russia, South Korea According with UK’s Department of Energy & Climate Change nuclear industry plans to develop around 16 gigawatts (GW) of new nuclear EDF → 4 EPRs (6.4GW) at Hinkley Point and Sizewell Hitachi → 2 or 3 new nuclear reactors at Wylfa and Oldbury NuGeneration → 3.6GW of new nuclear capacity at Moorside Fast-growing economies: China, India China has 28 reactors under construction and it is planned a three-fold increase in nuclear capacity to at least 58 GWe by 2020, then some 150 GWe by 2030 16 AP1000 reactors are planned to start to be constructed from 2014-2018 At least 6 ACC1000 in 4 different locations 2 EPRs in Guangdong Other technologies like VVER-1000, VVER-1200, CNP-600, etc are also envisioned Growing demand for nuclear power... Demand for nuclear power has increased in the past years and it is likely to keep on rising. Experienced countries: US, UK, Russia, South Korea According with UK’s Department of Energy & Climate Change nuclear industry plans to develop around 16 gigawatts (GW) of new nuclear EDF → 4 EPRs (6.4GW) at -
Radiation Hazard Location
Radiation Hazard Location Radiation Detector JS Stanley US Patent 8,399.859 B2 March 19, 2013 Using semi spherical PRESAGE with a lead collimator to detect contaminated Hot Cells Improving the Presage Polymer Radiosensitivity for Hot Cell and Glovebox 3D Characterization Adamovics, John; Farfan, Eduardo B.; Coleman, J. Rusty Health Physics (2013), 104(1), 63-67. RadBall is a novel, passive, radiation detection device that provides 3D mapping of radiation from areas where measurements have not been possible previously due to lack of access or extremely high radiation doses. This kind of technol. is beneficial when decommissioning and decontamination of nuclear facilities occur. The key components of the RadBall technol. include a tungsten outer shell that houses a radiosensitive PRESAGE polymer. The 1.0-cm-thick tungsten shell has a no. of holes that allow photons to reach the polymer, thus generating radiation tracks that are analyzed. Submerged RadBall Deployments in Hanford Site Hot Cells Containing 137CsCl Capsules Farfan, Eduardo B.; Coleman, J. Rusty; Stanley, Steven; Adamovics, John; Oldham, Mark; Thomas, Andrew Health Physics 103:100-106 (2012) The overall objective of this study was to demonstrate that a new technol., known as RadBall, could locate submerged radiol. hazards. RadBall is a novel, passive, radiation detection device that provides a 3-D visualization of radiation from areas where measurements have not been previously possible due to lack of access or extremely high radiation doses. This technol. has been under development during recent years, and all of its previous tests have included dry deployments. This study involved, for the first time, underwater RadBall deployments in hot cells contg. -
Compuestos Funcionales Presentes En La Cerveza Y Su Influencia En La Salud. Functional Compounds Present in Beer and Its Influen
Artículo científico Ordoñez, et al. COMPUESTOS FUNCIONALES PRESENTES EN LA CERVEZA Y SU INFLUENCIA EN LA SALUD. FUNCTIONAL COMPOUNDS PRESENT IN BEER AND ITS INFLUENCE ON HEALTH. Ordoñez-Araque Roberto1, Rodriguez-Villacres Johnny2, Urresto-Villegas Julio2 Narváez-Aldáz Christian1. 1Facultad de Salud y Bienestar. Escuela de Nutrición y Dietética. Universidad Iberoamericana del Ecuador, Quito, Ecuador. 2 Facultad de Ciencias Agrarias. Carrera de Ingeniería Agrícola mención Agroindustrial. Universidad Agraria del Ecuador, Guayaquil, Ecuador. Autor corresponsal: [email protected] Manuscrito recibido 03 de mayo de 2019. Aceptado para publicación, tras proceso de revisión, el 02 julio de 2019 Resumen La cerveza es una bebida milenaria elaborada a partir de varios procesos biotecnológicos a base de agua, cebada, lúpulo y levadura. Estos elementos otorgan a la cerveza una gran variedad de compuestos funcionales o bioactivos los cuales han sido de interés científico por su efectividad para el tratamiento de enfermedades causadas por estrés oxidativo como el cáncer y la ateroesclerosis. El presente artículo tiene como objetivo identificar los principales componentes bioactivos en la cerveza y su influencia en la salud humana. Se realizó una revisión sistemática consultando en 53 artículos de las principales bases de datos entre los años 2012-2019. Los resultados más importantes encontrados fueron que los compuestos funcionales en la cerveza provienen en un Qualitas, Vol. 17, 105-125. Julio 2019. ISSN: 1390-6569 105 Compuestos funcionales presentes en la cerveza y su influencia en la salud. 70% de la malta de cebada y el 30% del lúpulo, los principales son los compuestos fenólicos (Flavonoles, cumarinas, catequinas, proantocianidinas di y tri-oligoméricas, chalconas preniladas, isoxanthohumol, xanthohumol, desmetilxanthohumol, 6 y 8- prenilnaringenina. -
VERBAL BEHAVIOR by B. F. Skinner William James Lectures Harvard
VERBAL BEHAVIOR by B. F. Skinner William James Lectures Harvard University 1948 To be published by Harvard University Press. Reproduced by permission of B. F. Skinner† Preface In 1930, the Harvard departments of psychology and philosophy began sponsoring an endowed lecture series in honor of William James and continued to do so at irregular intervals for nearly 60 years. By the time Skinner was invited to give the lectures in 1947, the prestige of the engagement had been established by such illustrious speakers as John Dewey, Wolfgang Köhler, Edward Thorndike, and Bertrand Russell, and there can be no doubt that Skinner was aware that his reputation would rest upon his performance. His lectures were evidently effective, for he was soon invited to join the faculty at Harvard, where he was to remain for the rest of his career. The text of those lectures, possibly somewhat edited and modified by Skinner after their delivery, was preserved as an unpublished manuscript, dated 1948, and is reproduced here. Skinner worked on his analysis of verbal behavior for 23 years, from 1934, when Alfred North Whitehead announced his doubt that behaviorism could account for verbal behavior, to 1957, when the book Verbal Behavior was finally published, but there are two extant documents that reveal intermediate stages of his analysis. In the first decade of this period, Skinner taught several courses on language, literature, and behavior at Clark University, the University of Minnesota, and elsewhere. According to his autobiography, he used notes from these classes as the foundation for a class he taught on verbal behavior in the summer of 1947 at Columbia University. -
The Physical Basis of the Direction of Time (The Frontiers Collection), 5Th
the frontiers collection the frontiers collection Series Editors: A.C. Elitzur M.P. Silverman J. Tuszynski R. Vaas H.D. Zeh The books in this collection are devoted to challenging and open problems at the forefront of modern science, including related philosophical debates. In contrast to typical research monographs, however, they strive to present their topics in a manner accessible also to scientifically literate non-specialists wishing to gain insight into the deeper implications and fascinating questions involved. Taken as a whole, the series reflects the need for a fundamental and interdisciplinary approach to modern science. Furthermore, it is intended to encourage active scientists in all areas to ponder over important and perhaps controversial issues beyond their own speciality. Extending from quantum physics and relativity to entropy, consciousness and complex systems – the Frontiers Collection will inspire readers to push back the frontiers of their own knowledge. InformationandItsRoleinNature The Thermodynamic By J. G. Roederer Machinery of Life By M. Kurzynski Relativity and the Nature of Spacetime By V. Petkov The Emerging Physics of Consciousness Quo Vadis Quantum Mechanics? Edited by J. A. Tuszynski Edited by A. C. Elitzur, S. Dolev, N. Kolenda Weak Links Life – As a Matter of Fat Stabilizers of Complex Systems The Emerging Science of Lipidomics from Proteins to Social Networks By O. G. Mouritsen By P. Csermely Quantum–Classical Analogies Mind, Matter and the Implicate Order By D. Dragoman and M. Dragoman By P.T.I. Pylkkänen Knowledge and the World Quantum Mechanics at the Crossroads Challenges Beyond the Science Wars New Perspectives from History, Edited by M.